| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Etrat Hooshmandi, Rasoul Ghasemi, Parisa Iloun, Maryam Moosav. The neuroprotective effect of agmatine against amyloid β-induced apoptosis in primary cultured hippocampal cells involving ERK, Akt/GSK-3β, and TNF-α. Molecular biology reports. vol 46. issue 1. 2019-07-02. PMID:30474774. |
the neuroprotective effect of agmatine against amyloid β-induced apoptosis in primary cultured hippocampal cells involving erk, akt/gsk-3β, and tnf-α. |
2019-07-02 |
2023-08-13 |
rat |
| Min-Seok Kim, Geun-Hee Lee, Yong-Min Kim, Byoung-Wook Lee, Hae Yun Nam, U-Cheol Sim, Suk-Jung Choo, Seong-Woon Yu, Jae-Joong Kim, Yunhee Kim Kwon, Seong Who Ki. Angiotensin II Causes Apoptosis of Adult Hippocampal Neural Stem Cells and Memory Impairment Through the Action on AMPK-PGC1α Signaling in Heart Failure. Stem cells translational medicine. vol 6. issue 6. 2019-06-27. PMID:28244243. |
angiotensin ii causes apoptosis of adult hippocampal neural stem cells and memory impairment through the action on ampk-pgc1α signaling in heart failure. |
2019-06-27 |
2023-08-13 |
rat |
| Ai-Hua Liu, Min Chu, Yu-Ping Wan. Up-Regulation of Trem2 Inhibits Hippocampal Neuronal Apoptosis and Alleviates Oxidative Stress in Epilepsy via the PI3K/Akt Pathway in Mice. Neuroscience bulletin. vol 35. issue 3. 2019-06-26. PMID:30684126. |
up-regulation of trem2 inhibits hippocampal neuronal apoptosis and alleviates oxidative stress in epilepsy via the pi3k/akt pathway in mice. |
2019-06-26 |
2023-08-13 |
mouse |
| Qihua Pang, Yanru Li, Lingxue Meng, Guanyong Li, Zhiwei Luo, Ruifang Fa. Neurotoxicity of BPA, BPS, and BPB for the hippocampal cell line (HT-22): An implication for the replacement of BPA in plastics. Chemosphere. vol 226. 2019-06-25. PMID:30953899. |
to investigate the toxicities of bpa and its analogs on neurons, reactive oxygen species (ros) assay, annexin v-fitc (fluorescein) apoptosis detection assay, lactate dehydrogenase (ldh) cytotoxicity assay, and cell counting kit-8 assay were conducted to comprehensively assess the influence of different concentrations of bpa, bpb, and bps on ros, apoptosis, damage, and proliferation for hippocampal ht-22 cells, respectively. |
2019-06-25 |
2023-08-13 |
Not clear |
| Yu Zhao, Jinquan Cai, Zichen Liu, Yansheng Li, Chunxiong Zheng, Yadan Zheng, Qun Chen, Hongyun Chen, Feihe Ma, Yingli An, Lehui Xiao, Chuanlu Jiang, Linqi Shi, Chunsheng Kang, Yang Li. Nanocomposites Inhibit the Formation, Mitigate the Neurotoxicity, and Facilitate the Removal of β-Amyloid Aggregates in Alzheimer's Disease Mice. Nano letters. vol 19. issue 2. 2019-06-24. PMID:30444372. |
with the reduction of the pathological aβ oligomers, the nanocomposites attenuated the aβ-induced neuron damages, regained endocranial microglia's capability to phagocytose aβ, and eventually protected hippocampal neurons against apoptosis. |
2019-06-24 |
2023-08-13 |
mouse |
| Mengmeng Wang, Yanmeng Bi, Shanmei Zeng, Yuan Liu, Meng Shao, Kai Liu, Yanjia Deng, Ge Wen, Xuegang Sun, Ping Zeng, Linlin Jing, Zhiping L. Modified Xiaoyao San ameliorates depressive-like behaviors by triggering autophagosome formation to alleviate neuronal apoptosis. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 111. 2019-06-21. PMID:30841419. |
it suppresses the apoptosis by downregulaing condensation of heterochromatin and reducing hippocampal tdt-mediated dutp nick-end labeling (tunel)-positive cells. |
2019-06-21 |
2023-08-13 |
mouse |
| Yaghoob Farbood, Shahab Ghaderi, Masome Rashno, Seyed Esmaeil Khoshnam, Layasadat Khorsandi, Alireza Sarkaki, Mohammad Rashn. Sesamin: A promising protective agent against diabetes-associated cognitive decline in rats. Life sciences. vol 230. 2019-06-21. PMID:31150685. |
hippocampal oxidative stress and apoptosis of ca1 neurons play significant roles in the pathophysiology of diabetes-associated cognitive decline (dacd). |
2019-06-21 |
2023-08-13 |
rat |
| Mengzhu Li, Enjie Liu, Qiuzhi Zhou, Shihong Li, Xin Wang, Yanchao Liu, Lin Wang, Dongsheng Sun, Jinwang Ye, Yuan Gao, Xifei Yang, Jianjun Liu, Ying Yang, Jian-Zhi Wan. TRPC1 Null Exacerbates Memory Deficit and Apoptosis Induced by Amyloid-β. Journal of Alzheimer's disease : JAD. vol 63. issue 2. 2019-06-18. PMID:29660945. |
further studies demonstrated that trpc1 deletion did not affect cell apoptosis in physiological condition, but it exacerbated the aβ-induced cell death in mouse hippocampus. |
2019-06-18 |
2023-08-13 |
mouse |
| Junhua Li, Minyan Guo, Yafang Liu, Guiyun Wu, Liping Miao, Jing Zhang, Zhiyi Zuo, Yujuan L. Both GSK-3β/CRMP2 and CDK5/CRMP2 pathways participate in the protection of dexmedetomidine against propofol-induced learning and memory impairment in neonatal rats. Toxicological sciences : an official journal of the Society of Toxicology. 2019-06-12. PMID:31187143. |
propofol induced apoptosis in the hippocampal neurons and astrocytes, inhibited neuronal proliferation in the dg region, down-regulated the level of γ-aminobutyric acid (gaba) and glutamate in the hippocampus, and impaired long-term cognitive function. |
2019-06-12 |
2023-08-13 |
rat |
| Jinli Wang, Yuan Zheng, Xu Cheng, Fenfen Xu, Piaopiao Zhang, Xiao Zhou, Hongyang Zha. Inhibition of microRNA-34a Suppresses Epileptiform Discharges Through Regulating Notch Signaling and Apoptosis in Cultured Hippocampal Neurons. Neurochemical research. vol 44. issue 5. 2019-06-11. PMID:30877521. |
inhibition of microrna-34a suppresses epileptiform discharges through regulating notch signaling and apoptosis in cultured hippocampal neurons. |
2019-06-11 |
2023-08-13 |
rat |
| Zahra Jahangiri, Zahra Gholamnezhad, Mahmoud Hossein. Neuroprotective effects of exercise in rodent models of memory deficit and Alzheimer's. Metabolic brain disease. vol 34. issue 1. 2019-06-06. PMID:30443769. |
neuroperotective effects of exercise on the hippocampus seem to be increasing in immediate-early gene c-fos expression in dentate gyrus; enhancing the wnt3 expression and inhibiting glycogen synthase kinase-3β expression; increasing the 5-bro-mo-2'-deoxyridine-positive and doublecortin-positive cells (dentate gyrus); increasing the level of astrocytes glial fibrillary acidic protein and decrease in s100b protein, increasing in blood brain barrier integrity; prevention of oxidative stress injury, inducing morphological changes in astrocytes in the stratum radiatum of cornu ammonis 1(ca1) area; increase in cell proliferation and suppress apoptosis in dentate gyrus; increase in brain-derived neurotrophic factor and tropomyosin receptor kinase b expressions; enhancing the glycogen levels and normalizing the monocarboxylate transporter 2 expression. |
2019-06-06 |
2023-08-13 |
Not clear |
| Song-Yun Zhang, Su-Xiao Ji, Xiao-Mei Bai, Fang Yuan, Li-Hui Zhang, Jie L. L-3-n-butylphthalide attenuates cognitive deficits in db/db diabetic mice. Metabolic brain disease. vol 34. issue 1. 2019-06-06. PMID:30506335. |
l-nbp significantly ameliorated cognitive decline in type 2 diabetic mice, and this effect was accompanied by an improvement in hippocampal plasticity and an amelioration of oxidative stress, inflammation and apoptosis cascades. |
2019-06-06 |
2023-08-13 |
mouse |
| Wenqi Gao, Wei Wang, Gang Liu, Jing Zhang, Jian Yang, Zhifang Den. Allicin attenuated chronic social defeat stress induced depressive-like behaviors through suppression of NLRP3 inflammasome. Metabolic brain disease. vol 34. issue 1. 2019-06-06. PMID:30515710. |
allicin attenuated depressive-like behaviors of csds mice through reducing neuroinflammation, ameliorating iron abnromal accumulation, balacing oxidative stress, and attenuation neuronal apoptosis in the hippocampus via suppression of nlrp3 inflammasome. |
2019-06-06 |
2023-08-13 |
mouse |
| Yi Xiang, Xiaoxuan Fan, Ming Zhao, Qiang Guo, Shiwen Gu. CKIP-1 alleviates oxygen-glucose deprivation/reoxygenation-induced apoptosis and oxidative stress in cultured hippocampal neurons by downregulating Keap1 and activating Nrf2/ARE signaling. European journal of pharmacology. vol 848. 2019-06-06. PMID:30658115. |
ckip-1 alleviates oxygen-glucose deprivation/reoxygenation-induced apoptosis and oxidative stress in cultured hippocampal neurons by downregulating keap1 and activating nrf2/are signaling. |
2019-06-06 |
2023-08-13 |
Not clear |
| Yusuf Hussain, Sunil K Jain, Puneet K Samaiy. Short-term westernized (HFFD) diet fed in adolescent rats: Effect on glucose homeostasis, hippocampal insulin signaling, apoptosis and related cognitive and recognition memory function. Behavioural brain research. vol 361. 2019-06-04. PMID:30584898. |
short-term westernized (hffd) diet fed in adolescent rats: effect on glucose homeostasis, hippocampal insulin signaling, apoptosis and related cognitive and recognition memory function. |
2019-06-04 |
2023-08-13 |
rat |
| Sevim Şahin, Seren Gülşen Gürgen, Uğur Yazar, İmran İnce, Tülay Kamaşak, Elif Acar Arslan, Betül Diler Durgut, Beril Dilber, Ali Cans. Vitamin D protects against hippocampal apoptosis related with seizures induced by kainic acid and pentylenetetrazol in rats. Epilepsy research. vol 149. 2019-06-04. PMID:30584976. |
vitamin d protects against hippocampal apoptosis related with seizures induced by kainic acid and pentylenetetrazol in rats. |
2019-06-04 |
2023-08-13 |
rat |
| Sevim Şahin, Seren Gülşen Gürgen, Uğur Yazar, İmran İnce, Tülay Kamaşak, Elif Acar Arslan, Betül Diler Durgut, Beril Dilber, Ali Cans. Vitamin D protects against hippocampal apoptosis related with seizures induced by kainic acid and pentylenetetrazol in rats. Epilepsy research. vol 149. 2019-06-04. PMID:30584976. |
the effect of vitamin d on hippocampal apoptosis related with seizures has not been reported. |
2019-06-04 |
2023-08-13 |
rat |
| Sevim Şahin, Seren Gülşen Gürgen, Uğur Yazar, İmran İnce, Tülay Kamaşak, Elif Acar Arslan, Betül Diler Durgut, Beril Dilber, Ali Cans. Vitamin D protects against hippocampal apoptosis related with seizures induced by kainic acid and pentylenetetrazol in rats. Epilepsy research. vol 149. 2019-06-04. PMID:30584976. |
therefore, in this study, it was aimed to evaluate the effects of vitamin d on hippocampal apoptosis related with seizures by using pentylenetetrazol (ptz) and kainic acid (ka) in rats. |
2019-06-04 |
2023-08-13 |
rat |
| Qingzhi Li, Pengcheng Wang, Chuixue Huang, Baozhi Chen, Jiabin Liu, Mingmei Zhao, Jiannong Zha. N-Acetyl Serotonin Protects Neural Progenitor Cells Against Oxidative Stress-Induced Apoptosis and Improves Neurogenesis in Adult Mouse Hippocampus Following Traumatic Brain Injury. Journal of molecular neuroscience : MN. vol 67. issue 4. 2019-05-29. PMID:30684239. |
n-acetyl serotonin protects neural progenitor cells against oxidative stress-induced apoptosis and improves neurogenesis in adult mouse hippocampus following traumatic brain injury. |
2019-05-29 |
2023-08-13 |
mouse |
| Shishuang Zhang, Yongle Zhi, Fei Li, Shan Huang, Huabin Gao, Zhaoli Han, Xintong Ge, Dai Li, Fanglian Chen, Xiaodong Kong, Ping Le. Transplantation of in vitro cultured endothelial progenitor cells repairs the blood-brain barrier and improves cognitive function of APP/PS1 transgenic AD mice. Journal of the neurological sciences. vol 387. 2019-05-28. PMID:29571873. |
we observed that aβ senile plaque deposition was decreased and hippocampal cell apoptosis was reduced after epcs transplantation. |
2019-05-28 |
2023-08-13 |
mouse |