| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jie Zheng, Su Min, Bin Hu, Qin Liu, Yunqiang Wa. Nrdp1 is involved in hippocampus apoptosis in cardiopulmonary bypass-induced cognitive dysfunction via the regulation of ErbB3 protein levels. International journal of molecular medicine. vol 43. issue 4. 2019-07-30. PMID:30720051. |
the results revealed that nrdp1 is associated with hippocampus neuronal apoptosis and pocd following cpb in rats. |
2019-07-30 |
2023-08-13 |
rat |
| Jie Zheng, Su Min, Bin Hu, Qin Liu, Yunqiang Wa. Nrdp1 is involved in hippocampus apoptosis in cardiopulmonary bypass-induced cognitive dysfunction via the regulation of ErbB3 protein levels. International journal of molecular medicine. vol 43. issue 4. 2019-07-30. PMID:30720051. |
the overexpression of nrdp1 altered the cognitive function of the rats which was inhibited by cpb, and additionally inhibited the viability and increased the apoptosis of primary hippocampus neuron cells under h/r treatment. |
2019-07-30 |
2023-08-13 |
rat |
| Jie Zheng, Su Min, Bin Hu, Qin Liu, Yunqiang Wa. Nrdp1 is involved in hippocampus apoptosis in cardiopulmonary bypass-induced cognitive dysfunction via the regulation of ErbB3 protein levels. International journal of molecular medicine. vol 43. issue 4. 2019-07-30. PMID:30720051. |
furthermore, knockdown of nrdp1 promoted the viability of primary hippocampus neuron cells and decreased the apoptosis of cells under h/r treatment. |
2019-07-30 |
2023-08-13 |
rat |
| Jie Zheng, Su Min, Bin Hu, Qin Liu, Yunqiang Wa. Nrdp1 is involved in hippocampus apoptosis in cardiopulmonary bypass-induced cognitive dysfunction via the regulation of ErbB3 protein levels. International journal of molecular medicine. vol 43. issue 4. 2019-07-30. PMID:30720051. |
the results of the present study suggested that cpb may induce apoptosis in the hippocampus of aged rats. |
2019-07-30 |
2023-08-13 |
rat |
| Lu Xu, Ling Ding, Yuanqi Su, Ruyue Shao, Jie Liu, Yan Huan. Neuroprotective effects of curcumin against rats with focal cerebral ischemia-reperfusion injury. International journal of molecular medicine. vol 43. issue 4. 2019-07-30. PMID:30816425. |
transmission electron microscope was utilized to observe morphological changes of hippocampal neurons; hematoxylin and eosin staining was used to observe morphological changes of brain tissue; and the terminal deoxynucleotidyl transferase (tdt)‑mediated dutp nick end labeling method detected neurons apoptosis of hippocampal ca1. |
2019-07-30 |
2023-08-13 |
rat |
| Yuichiro Fujieda, Simone Mader, Venkatesh Jeganathan, Yoshiyuki Arinuma, Yuka Shimizu, Masaru Kato, Kenji Oku, Akiko Minami, Chikara Shimizu, Shinsuke Yasuda, Tatsuya Atsum. Clinical significance of anti-DNA/N-methyl-D-aspartate receptor 2 antibodies in de novo and post-steroid cases with neuropsychiatric systemic lupus erythematosus. International journal of rheumatic diseases. vol 22. issue 3. 2019-07-29. PMID:30358102. |
these antibodies induce apoptosis of hippocampus neurons and psychiatric disorder in mice and humans. |
2019-07-29 |
2023-08-13 |
mouse |
| Ping Sun, Jun-Bo Yin, Li-Hua Liu, Jian Guo, Sheng-Hai Wang, Chun-Hui Qu, Chun-Xia Wan. Protective role of Dihydromyricetin in Alzheimer's disease rat model associated with activating AMPK/SIRT1 signaling pathway. Bioscience reports. vol 39. issue 1. 2019-07-26. PMID:30498091. |
then, the inflammatory cytokines expressions were determined by radioimmunoassay while expressions of ampk/sirt1 pathway-related proteins by western blot; and the apoptosis of hippocampal cells was detected by tdt-mediated dutp nick end labeling assay. |
2019-07-26 |
2023-08-13 |
rat |
| Ping Sun, Jun-Bo Yin, Li-Hua Liu, Jian Guo, Sheng-Hai Wang, Chun-Hui Qu, Chun-Xia Wan. Protective role of Dihydromyricetin in Alzheimer's disease rat model associated with activating AMPK/SIRT1 signaling pathway. Bioscience reports. vol 39. issue 1. 2019-07-26. PMID:30498091. |
meanwhile, the apoptosis of hippocampal cells was significantly up-regulated with decreased bcl-2 and increased bax, as compared with sham rats (all |
2019-07-26 |
2023-08-13 |
rat |
| Morgan E Stevenson, Nicole A Lensmire, Rodney A Swai. Astrocytes and radial glia-like cells, but not neurons, display a nonapoptotic increase in caspase-3 expression following exercise. Brain and behavior. vol 8. issue 10. 2019-07-22. PMID:30240148. |
interestingly, there have also been reports of apoptosis in the hippocampus following aerobic exercise. |
2019-07-22 |
2023-08-13 |
Not clear |
| Morgan E Stevenson, Nicole A Lensmire, Rodney A Swai. Astrocytes and radial glia-like cells, but not neurons, display a nonapoptotic increase in caspase-3 expression following exercise. Brain and behavior. vol 8. issue 10. 2019-07-22. PMID:30240148. |
this experiment aimed to identify which population of hippocampal cells undergoes apoptosis after an acute bout of exercise. |
2019-07-22 |
2023-08-13 |
Not clear |
| Biao Cai, Shu Ye, Yan Wang, Ting-Ting Wang, Liang Wang, Ai-Juan Jiang, Zheng-Qing Fang, Guo-Ming Shen, Dao-Jun Xi. [Effects of Huangpu Tongqiao capsule on apoptosis of Alzheimer's disease cell model]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 43. issue 11. 2019-07-18. PMID:29945394. |
the loss of hippocampal neurons is one of the main pathological features of alzheimer's disease (ad), which is related to the apoptosis of hippocampal neurons. |
2019-07-18 |
2023-08-13 |
Not clear |
| Biao Cai, Shu Ye, Yan Wang, Ting-Ting Wang, Liang Wang, Ai-Juan Jiang, Zheng-Qing Fang, Guo-Ming Shen, Dao-Jun Xi. [Effects of Huangpu Tongqiao capsule on apoptosis of Alzheimer's disease cell model]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 43. issue 11. 2019-07-18. PMID:29945394. |
this study is to investigate the mechanism of neuroprotective effect of huangpu tongqiao capsule in the treatment of ad, through observing the effect of huangpu tongqiao capsule containing serum on cell injury of primary cultured hippocampal neurons induced by aβ₂₅₋₃₅ via inhibiting the cell apoptosis. |
2019-07-18 |
2023-08-13 |
Not clear |
| Biao Cai, Shu Ye, Yan Wang, Ting-Ting Wang, Liang Wang, Ai-Juan Jiang, Zheng-Qing Fang, Guo-Ming Shen, Dao-Jun Xi. [Effects of Huangpu Tongqiao capsule on apoptosis of Alzheimer's disease cell model]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 43. issue 11. 2019-07-18. PMID:29945394. |
after primary cultured hippocampal neurons ad cell model was induced by aβ₂₅₋₃₅, cell survival rate was detected by mtt, cell apoptosis rate was assayed by flow cytometry, and protein expressions of bax, cyt c and caspase-3 were determined by western blot analysis. |
2019-07-18 |
2023-08-13 |
Not clear |
| Biao Cai, Shu Ye, Yan Wang, Ting-Ting Wang, Liang Wang, Ai-Juan Jiang, Zheng-Qing Fang, Guo-Ming Shen, Dao-Jun Xi. [Effects of Huangpu Tongqiao capsule on apoptosis of Alzheimer's disease cell model]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 43. issue 11. 2019-07-18. PMID:29945394. |
the results showed that the primary cultured hippocampal neurons were cultured successfully, and cells grew mature at seventh days; compared with normal group, the survival rate of hippocampal neurons in ad cell model group was decreased, the apoptosis rate of hippocampal neurons was increased, and the protein expressions of bax, cyt c and caspase-3 were increased ( |
2019-07-18 |
2023-08-13 |
Not clear |
| Wen-Tao Fan, Qian Wan. [Mechanism of Acori Tatarinowii Rhizoma-Curcumae Radix treating depression based on network pharmacology]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 43. issue 12. 2019-07-18. PMID:29950083. |
gene kegg pathway enrichment analysis showed associations with misfolded protein, secretory hormone secretion, and apoptosis of hippocampal neurons. |
2019-07-18 |
2023-08-13 |
Not clear |
| Wen-Tao Fan, Qian Wan. [Mechanism of Acori Tatarinowii Rhizoma-Curcumae Radix treating depression based on network pharmacology]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 43. issue 12. 2019-07-18. PMID:29950083. |
the possible mechanism for treating depression is the adjustment of wrong folding protein, sex hormone secretion and apoptosis of hippocampal neurons. |
2019-07-18 |
2023-08-13 |
Not clear |
| Tanzhen Xu, Lingling Sun, Xiaoyan Shen, Yali Chen, Yanyan Yin, Junyan Zhang, Dake Huang, Weiping Li, Weizu L. NADPH oxidase 2-mediated NLRP1 inflammasome activation involves in neuronal senescence in hippocampal neurons in vitro. International immunopharmacology. vol 69. 2019-07-18. PMID:30677569. |
the results showed that, compared with 6 d group, the neuronal apoptosis and β-galactosidase (β-gal) expression were significantly increased, and the microtubule-associated protein 2 (map2) expression significantly decreased in primary hippocampal neurons cultured for 12 d. |
2019-07-18 |
2023-08-13 |
Not clear |
| Liyuan Zhang, Ping Huang, Hui Chen, Wen Tan, Jiawei Lu, Wei Liu, Jingdong Wang, Shuyu Zhang, Wei Zhu, Jianping Cao, Ye Tian, Hongying Yan. The inhibitory effect of minocycline on radiation-induced neuronal apoptosis via AMPKα1 signaling-mediated autophagy. Scientific reports. vol 7. issue 1. 2019-07-12. PMID:29180765. |
our previous study has found that minocycline, a clinical available antibiotics that can easily cross the blood brain barrier, mitigates radiation-induced long-term memory loss in rats, accompanied by decreased hippocampal neuron apoptosis. |
2019-07-12 |
2023-08-13 |
mouse |
| Huilin Wang, Zheng Li, Jingyan Gao, Qingwu Lia. Circular RNA circPTK2 regulates oxygen-glucose deprivation-activated microglia-induced hippocampal neuronal apoptosis via miR-29b-SOCS-1-JAK2/STAT3-IL-1β signaling. International journal of biological macromolecules. vol 129. 2019-07-12. PMID:30742923. |
circular rna circptk2 regulates oxygen-glucose deprivation-activated microglia-induced hippocampal neuronal apoptosis via mir-29b-socs-1-jak2/stat3-il-1β signaling. |
2019-07-12 |
2023-08-13 |
Not clear |
| Huilin Wang, Zheng Li, Jingyan Gao, Qingwu Lia. Circular RNA circPTK2 regulates oxygen-glucose deprivation-activated microglia-induced hippocampal neuronal apoptosis via miR-29b-SOCS-1-JAK2/STAT3-IL-1β signaling. International journal of biological macromolecules. vol 129. 2019-07-12. PMID:30742923. |
il-1β was confirmed to be an apoptosis inducer of hippocampal neurons. |
2019-07-12 |
2023-08-13 |
Not clear |