| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shu-Ting Yin, Ming-Liang Tang, Hong-Min Deng, Tai-Ran Xing, Ju-Tao Chen, Hui-Li Wang, Di-Yun Rua. Epigallocatechin-3-gallate induced primary cultures of rat hippocampal neurons death linked to calcium overload and oxidative stress. Naunyn-Schmiedeberg's archives of pharmacology. vol 379. issue 6. 2010-02-16. PMID:19221718. |
furthermore, treatment of hippocampal neurons with egcg resulted in an elevation of caspase-3 and caspase-9 activities with no significant accompaniment of lactate dehydrogenase release, which provided further evidence that apoptosis was the dominant mode of egcg-induced cell death in cultures of hippocampal neurons. |
2010-02-16 |
2023-08-12 |
rat |
| Shouping Wang, Kelly Peretich, Yifan Zhao, Ge Liang, Qingcheng Meng, Huafeng We. Anesthesia-induced neurodegeneration in fetal rat brains. Pediatric research. vol 66. issue 4. 2010-02-05. PMID:20016413. |
fetal brains were then evaluated for apoptosis, using caspase-3 immunohistochemistry in the ca1 region of the hippocampus and the retrosplenial cortex (rs). |
2010-02-05 |
2023-08-12 |
rat |
| Simon J Fung, Ming-Chu Xi, Jian-Hua Zhang, Jack Yamuy, Sharon Sampogna, Kevin L Tsai, Vincent Lim, Francisco R Morales, Michael H Chas. Eszopiclone prevents excitotoxicity and neurodegeneration in the hippocampus induced by experimental apnea. Sleep. vol 32. issue 12. 2010-02-04. PMID:20041595. |
this study was designed to determine the effects of eszopiclone on apnea-induced excitotoxic synaptic processes and apoptosis in the hippocampus. |
2010-02-04 |
2023-08-12 |
Not clear |
| Hao Li, Mingjiang Yao, Li Xu, Jiangang Liu, Wenming Zha. [Effects of Huannao Yicong decoction on cognitive function and expression of Bcl-2 and Bax protein of hippocampus in cognitive impairment rats]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 34. issue 20. 2010-01-29. PMID:20069907. |
to observe the intervention effects of huannao yicong decoction on cognitive function and apoptosis and expression of relative regulative gene of hippocampus in cognitive impairment rats induced by complex factors. |
2010-01-29 |
2023-08-12 |
rat |
| Tomomi Michiue, Li Quan, Takaki Ishikawa, Bao-Li Zhu, Hitoshi Maed. Quantitative analysis of single-stranded DNA immunoreactivity as a marker of neuronal apoptosis in hippocampus with regard to the causes of death in medicolegal autopsy. Legal medicine (Tokyo, Japan). vol 11 Suppl 1. 2010-01-26. PMID:19278886. |
quantitative analysis of single-stranded dna immunoreactivity as a marker of neuronal apoptosis in hippocampus with regard to the causes of death in medicolegal autopsy. |
2010-01-26 |
2023-08-12 |
Not clear |
| Tomomi Michiue, Li Quan, Takaki Ishikawa, Bao-Li Zhu, Hitoshi Maed. Quantitative analysis of single-stranded DNA immunoreactivity as a marker of neuronal apoptosis in hippocampus with regard to the causes of death in medicolegal autopsy. Legal medicine (Tokyo, Japan). vol 11 Suppl 1. 2010-01-26. PMID:19278886. |
the present study immunohistochemically investigated single-stranded dna (ssdna) as a marker of dna injury during apoptosis and programmed cell death to evaluate neuronal damage in the hippocampus with regard to the cause of death in serial medicolegal autopsy cases (n=335, <48 h postmortem). |
2010-01-26 |
2023-08-12 |
Not clear |
| Kerry-Ann da Costa, Kiranmai S Rai, Corneliu N Craciunescu, Komal Parikh, Mihai G Mehedint, Lisa M Sanders, Audrey McLean-Pottinger, Steven H Zeise. Dietary docosahexaenoic acid supplementation modulates hippocampal development in the Pemt-/- mouse. The Journal of biological chemistry. vol 285. issue 2. 2010-01-26. PMID:19889625. |
also, they had 60% more neural progenitor cell proliferation (p < 0.05), 60% more neuronal apoptosis (p < 0.01), and 30% less calretinin expression (p < 0.05; a marker of neuronal differentiation) in the hippocampus compared with wt. |
2010-01-26 |
2023-08-12 |
mouse |
| Hui-Ling Gao, Wei Zheng, Na Xin, Zhi-Hong Chi, Zhen-Yu Wang, Jie Chen, Zhan-You Wan. Zinc deficiency reduces neurogenesis accompanied by neuronal apoptosis through caspase-dependent and -independent signaling pathways. Neurotoxicity research. vol 16. issue 4. 2010-01-22. PMID:19548052. |
meanwhile, the apoptosis proteins, including fas, fas ligand (fasl), apoptosis inducing factor (aif), and caspase-3, were significantly activated in zinc-deficient mouse hippocampus. |
2010-01-22 |
2023-08-12 |
mouse |
| Hui-Ling Gao, Wei Zheng, Na Xin, Zhi-Hong Chi, Zhen-Yu Wang, Jie Chen, Zhan-You Wan. Zinc deficiency reduces neurogenesis accompanied by neuronal apoptosis through caspase-dependent and -independent signaling pathways. Neurotoxicity research. vol 16. issue 4. 2010-01-22. PMID:19548052. |
these data suggest that chronic treatment with zinc-deficient diet results in reduction in hippocampal neurogenesis and increases neuronal apoptosis, indicating that zinc deficiency is associated with destroying structural plasticity in the hippocampus. |
2010-01-22 |
2023-08-12 |
mouse |
| D A Lanshakov, V V Bulygina, I V Romanova, N N Dygal. Immunohistochemical analysis of active caspase-3 expression in structures of neonatal brain. Bulletin of experimental biology and medicine. vol 147. issue 5. 2010-01-20. PMID:19907758. |
taking into account the role of caspase-3 in apoptosis, these differences can indicate different intensity of programmed cell death in different fields of the forming hippocampus. |
2010-01-20 |
2023-08-12 |
rat |
| T Yawno, J J Hirst, M Castillo-Melendez, D W Walke. Role of neurosteroids in regulating cell death and proliferation in the late gestation fetal brain. Neuroscience. vol 163. issue 3. 2010-01-14. PMID:19591903. |
thus, steroids such as ap appear to influence the constitutive rate of apoptosis and proliferation in the hippocampus and cerebellum of the fetal brain, and suggest an important role for neurosteroids in the development of the brain. |
2010-01-14 |
2023-08-12 |
Not clear |
| Adama Diarra, Thangiah Geetha, Pamella Potter, Jeganathan Ramesh Bab. Signaling of the neurotrophin receptor p75 in relation to Alzheimer's disease. Biochemical and biophysical research communications. vol 390. issue 3. 2009-12-29. PMID:19818333. |
here, it is demonstrated that all neurotrophins that activated p75, without co-activation of the relevant trk co-receptor, mediated apoptosis in hippocampal neurons. |
2009-12-29 |
2023-08-12 |
Not clear |
| Adama Diarra, Thangiah Geetha, Pamella Potter, Jeganathan Ramesh Bab. Signaling of the neurotrophin receptor p75 in relation to Alzheimer's disease. Biochemical and biophysical research communications. vol 390. issue 3. 2009-12-29. PMID:19818333. |
thus, proneurotrophins and amyloid beta peptides (abeta) can induce p75-mediated apoptosis in hippocampal neurons since they do not bind or activate trk receptors. |
2009-12-29 |
2023-08-12 |
Not clear |
| Xin Chen, Ke-Li Zhang, Shu-Yuan Yang, Jing-Fei Dong, Jian-Ning Zhan. Glucocorticoids aggravate retrograde memory deficiency associated with traumatic brain injury in rats. Journal of neurotrauma. vol 26. issue 2. 2009-12-17. PMID:19236166. |
we hypothesize that glucocorticoids promote post-traumatic hippocampal apoptosis, resulting in retrograde memory deficiency associated with traumatic brain injury (tbi). |
2009-12-17 |
2023-08-12 |
rat |
| Xin Chen, Ke-Li Zhang, Shu-Yuan Yang, Jing-Fei Dong, Jian-Ning Zhan. Glucocorticoids aggravate retrograde memory deficiency associated with traumatic brain injury in rats. Journal of neurotrauma. vol 26. issue 2. 2009-12-17. PMID:19236166. |
in the present study, we tested this hypothesis by measuring spatial memory deficiency in rats subjected to fluid percussion injury (fpi) and receiving dexamethasone (dxm at 0.5-10 mg/kg) or methylprednisolone (mp at 5-30 mg/kg); we also examined neuronal apoptosis in hippocampus. |
2009-12-17 |
2023-08-12 |
rat |
| Xin Chen, Ke-Li Zhang, Shu-Yuan Yang, Jing-Fei Dong, Jian-Ning Zhan. Glucocorticoids aggravate retrograde memory deficiency associated with traumatic brain injury in rats. Journal of neurotrauma. vol 26. issue 2. 2009-12-17. PMID:19236166. |
the data suggest that glucocorticoid therapy for tbi may increase neuronal apoptosis in hippocampus and, as a result, aggravate retrograde memory deficits induced by tbi. |
2009-12-17 |
2023-08-12 |
rat |
| Heather N Richardson, Stephanie H Chan, Elena F Crawford, Youn Kyung Lee, Cindy K Funk, George F Koob, Chitra D Mandya. Permanent impairment of birth and survival of cortical and hippocampal proliferating cells following excessive drinking during alcohol dependence. Neurobiology of disease. vol 36. issue 1. 2009-12-07. PMID:19501165. |
increased hippocampal apoptosis and neuronal degeneration following alcohol exposure suggest a loss in neuronal turnover and indicate that the hippocampal neurogenic niche is highly vulnerable to alcohol. |
2009-12-07 |
2023-08-12 |
Not clear |
| Mihai D Niculescu, Daniel S Lup. High fat diet-induced maternal obesity alters fetal hippocampal development. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 27. issue 7. 2009-12-01. PMID:19695321. |
apoptosis in the hippocampus was decreased (ammon's horn and fimbria). |
2009-12-01 |
2023-08-12 |
Not clear |
| Mihai D Niculescu, Daniel S Lup. High fat diet-induced maternal obesity alters fetal hippocampal development. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 27. issue 7. 2009-12-01. PMID:19695321. |
these data indicate that, under the influence of a maternal high-fat diet administered prior and during gestation, fetal hippocampal development is altered at embryonic day 17, as indicated by region-specific changes in proliferation of neural precursors, decreased apoptosis, and by decreased neuronal differentiation within the dentate gyrus. |
2009-12-01 |
2023-08-12 |
Not clear |
| Masayuki Fukui, Ji-Hoon Song, Jinyoung Choi, Hye Joung Choi, Bao Ting Zh. Mechanism of glutamate-induced neurotoxicity in HT22 mouse hippocampal cells. European journal of pharmacology. vol 617. issue 1-3. 2009-11-30. PMID:19580806. |
there is considerable controversy in the literature with regard to whether glutamate-induced cell death in cultured ht22 cells (an immortalized mouse hippocampal cell line) is apoptosis, necrosis, or a new form of cell death. |
2009-11-30 |
2023-08-12 |
mouse |