| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Junxiao Liu, Dai Han, Yan Li, Liangkai Zheng, Chengwu Gu, Zhongxian Piao, William W Au, Xijin Xu, Xia Hu. Lead affects apoptosis and related gene XIAP and Smac expression in the hippocampus of developing rats. Neurochemical research. vol 35. issue 3. 2010-04-30. PMID:19911273. |
to replicate aspects of this neurotoxicity, we examined the effect of lead on the expression of apoptosis and of apoptosis-related genes, xiap (x chromosome-linked inhibitor of apoptosis protein) and smac (second mitochondrial activator of caspase), in the hippocampus of developing rats. |
2010-04-30 |
2023-08-12 |
rat |
| Junxiao Liu, Dai Han, Yan Li, Liangkai Zheng, Chengwu Gu, Zhongxian Piao, William W Au, Xijin Xu, Xia Hu. Lead affects apoptosis and related gene XIAP and Smac expression in the hippocampus of developing rats. Neurochemical research. vol 35. issue 3. 2010-04-30. PMID:19911273. |
pb content was determined in blood, and the apoptosis indexes and xiap and smac gene expression were analyzed in the hippocampus. |
2010-04-30 |
2023-08-12 |
rat |
| Junxiao Liu, Dai Han, Yan Li, Liangkai Zheng, Chengwu Gu, Zhongxian Piao, William W Au, Xijin Xu, Xia Hu. Lead affects apoptosis and related gene XIAP and Smac expression in the hippocampus of developing rats. Neurochemical research. vol 35. issue 3. 2010-04-30. PMID:19911273. |
our data indicate that exposure to pb(ac)2 caused a dose-dependent and significant increase of apoptosis in the hippocampus of developing rats through depressing the expression of the xiap but not the smac genes. |
2010-04-30 |
2023-08-12 |
rat |
| Hei-Jen Huang, Keng-Chen Liang, Yen-Yu Chang, Hsing-Chieh Ke, Jia-Yu Lin, Hsiu Mei Hsieh-L. The interaction between acute oligomer Abeta(1-40) and stress severely impaired spatial learning and memory. Neurobiology of learning and memory. vol 93. issue 1. 2010-04-29. PMID:19660564. |
therefore, apoptosis and synaptic dysfunction in the hippocampus severely induced the impairment of spatial learning and memory. |
2010-04-29 |
2023-08-12 |
mouse |
| Xin-Wen Huang, Zheng-Yan Zhao, Chai J. [Effects of hypothyroidism on apoptosis and the expression of Bcl-2 and Bax gene in the neonatal rat hippocampus neurons]. Zhonghua er ke za zhi = Chinese journal of pediatrics. vol 43. issue 1. 2010-04-26. PMID:15796810. |
[effects of hypothyroidism on apoptosis and the expression of bcl-2 and bax gene in the neonatal rat hippocampus neurons]. |
2010-04-26 |
2023-08-12 |
rat |
| Xin-Wen Huang, Zheng-Yan Zhao, Chai J. [Effects of hypothyroidism on apoptosis and the expression of Bcl-2 and Bax gene in the neonatal rat hippocampus neurons]. Zhonghua er ke za zhi = Chinese journal of pediatrics. vol 43. issue 1. 2010-04-26. PMID:15796810. |
this study was designed to investigate the effects of hypothyroidism on apoptosis and the expression of bcl-2 and bax gene in the developing rat hippocampus neurons and to explore the mechanism of brain development regulated by thyroid hormone. |
2010-04-26 |
2023-08-12 |
rat |
| Chun Lai Nie, Yan Wei, Xinyong Chen, Yan Ying Liu, Wen Dui, Ying Liu, Martyn C Davies, Saul J B Tendler, Rong Giao H. Formaldehyde at low concentration induces protein tau into globular amyloid-like aggregates in vitro and in vivo. PloS one. vol 2. issue 7. 2010-04-23. PMID:17637844. |
our previous results show that neuronal tau aggregates in formaldehyde solution and that aggregated tau induces apoptosis of sh-sy5y and hippocampal cells. |
2010-04-23 |
2023-08-12 |
cattle |
| Yun-Hee Sung, Mal-Soon Shin, Sehyung Cho, Hyung-Hwan Baik, Byung-Kwan Jin, Hyun-Kyung Chang, Eun-Kyu Lee, Chang-Ju Ki. Depression-like state in maternal rats induced by repeated separation of pups is accompanied by a decrease of cell proliferation and an increase of apoptosis in the hippocampus. Neuroscience letters. vol 470. issue 1. 2010-04-06. PMID:20043974. |
depression-like state in maternal rats induced by repeated separation of pups is accompanied by a decrease of cell proliferation and an increase of apoptosis in the hippocampus. |
2010-04-06 |
2023-08-12 |
rat |
| Yun-Hee Sung, Mal-Soon Shin, Sehyung Cho, Hyung-Hwan Baik, Byung-Kwan Jin, Hyun-Kyung Chang, Eun-Kyu Lee, Chang-Ju Ki. Depression-like state in maternal rats induced by repeated separation of pups is accompanied by a decrease of cell proliferation and an increase of apoptosis in the hippocampus. Neuroscience letters. vol 470. issue 1. 2010-04-06. PMID:20043974. |
based on the present results, it is suggested that separation of pups might induce a depressed-like state in the maternal rats with reduced cell proliferation and increased apoptosis in the hippocampus, resulting in memory impairment of maternal rats. |
2010-04-06 |
2023-08-12 |
rat |
| Wei-Zu Li, Wei-Ping Li, Yu-You Yao, Wen Zhang, Yan-Yan Yin, Guo-Cui Wu, Hui-Ling Gon. Glucocorticoids increase impairments in learning and memory due to elevated amyloid precursor protein expression and neuronal apoptosis in 12-month old mice. European journal of pharmacology. vol 628. issue 1-3. 2010-04-05. PMID:19948164. |
furthermore, dexamethasone treatment induced cortex and hippocampus neuron apoptosis as well as increasing the activity of caspase-9 and caspase-3. |
2010-04-05 |
2023-08-12 |
mouse |
| Ting-Ting Yang, Chao-Tien Hsu, Yu-Min Ku. Cell-derived soluble oligomers of human amyloid-beta peptides disturb cellular homeostasis and induce apoptosis in primary hippocampal neurons. Journal of neural transmission (Vienna, Austria : 1996). vol 116. issue 12. 2010-04-02. PMID:19809865. |
cell-derived soluble oligomers of human amyloid-beta peptides disturb cellular homeostasis and induce apoptosis in primary hippocampal neurons. |
2010-04-02 |
2023-08-12 |
human |
| Hongmei Shen, Ying Yuan, Fei Ding, Nan Hu, Jie Liu, Xiaosong G. Achyranthes bidentata polypeptides confer neuroprotection through inhibition of reactive oxygen species production, Bax expression, and mitochondrial dysfunction induced by overstimulation of N-methyl-D-aspartate receptors. Journal of neuroscience research. vol 88. issue 3. 2010-03-30. PMID:19774671. |
achyranthes bidentata polypeptides (abpp), the important constituents separated from the aqueous extract of achyranthes bidentata, have been shown to attenuate n-methyl-d-aspartate (nmda)-induced cell apoptosis in cultured hippocampal neurons through differential modulation of nr2a- and nr2b-containing nmda receptors. |
2010-03-30 |
2023-08-12 |
rat |
| Shuang Yu, Alexandre V Patchev, Yan Wu, Jie Lu, Florian Holsboer, Jing-Zhong Zhang, Nuno Sousa, Osborne F X Almeid. Depletion of the neural precursor cell pool by glucocorticoids. Annals of neurology. vol 67. issue 1. 2010-03-25. PMID:20186952. |
preclinical studies have demonstrated that gcs have a major influence on hippocampal cell turnover by inhibiting neurogenesis and stimulating apoptosis of mature neurons. |
2010-03-25 |
2023-08-12 |
Not clear |
| Christian Østergaard, Stephen L Leib, Ian Rowland, Christian T Brand. Bacteremia causes hippocampal apoptosis in experimental pneumococcal meningitis. BMC infectious diseases. vol 10. 2010-03-12. PMID:20044936. |
bacteremia causes hippocampal apoptosis in experimental pneumococcal meningitis. |
2010-03-12 |
2023-08-12 |
Not clear |
| Ping He, Ai-guo Wang, Tao Xia, Ping Gao, Qiang Niu, Li-juan Guo, Xue-min Che. Mechanisms underlying the developmental neurotoxic effect of PBDE-47 and the enhanced toxicity associated with its combination with PCB153 in rats. Neurotoxicology. vol 30. issue 6. 2010-03-09. PMID:19576244. |
to explore the mechanisms underlying the developmental neurotoxic effect of pbde-47 and its interaction with pcb153, expression levels of mrna and proteins of the x-chromosome-linked inhibitor of apoptosis protein (xiap), death associated protein kinase (dapk), caspase3, caspase12 and cytochrome c in the hippocampus of 2-month-old rats exposed to a single oral dose of pbde-47 and/or pcb153 on post natal day (pnd) 10 were examined. |
2010-03-09 |
2023-08-12 |
rat |
| S Steiger-Barraissoul, A Ram. Serum deprivation induced autophagy and predominantly an AIF-dependent apoptosis in hippocampal HT22 neurons. Apoptosis : an international journal on programmed cell death. vol 14. issue 11. 2010-03-09. PMID:19757066. |
serum deprivation induced autophagy and predominantly an aif-dependent apoptosis in hippocampal ht22 neurons. |
2010-03-09 |
2023-08-12 |
Not clear |
| S Steiger-Barraissoul, A Ram. Serum deprivation induced autophagy and predominantly an AIF-dependent apoptosis in hippocampal HT22 neurons. Apoptosis : an international journal on programmed cell death. vol 14. issue 11. 2010-03-09. PMID:19757066. |
the results of the current study suggest that sd induced predominantly caspase-independent apoptosis in hippocampal ht22 cells and that inhibition of autophagy is rather deleterious than protective. |
2010-03-09 |
2023-08-12 |
Not clear |
| Kerstin Göbel, Nico Melzer, Alexander M Herrmann, Michael K Schuhmann, Stefan Bittner, Chi Wang Ip, Thomas Hünig, Sven G Meuth, Heinz Wiend. Collateral neuronal apoptosis in CNS gray matter during an oligodendrocyte-directed CD8(+) T cell attack. Glia. vol 58. issue 4. 2010-03-08. PMID:19780193. |
we studied mechanisms and kinetics of oligodendroglial and neuronal apoptosis in the neocortex and hippocampus, using multicolor staining for different cell types and activated caspase-3. |
2010-03-08 |
2023-08-12 |
mouse |
| Yuanjie Sun, Ju-Suk Nam, Dong-Hoon Han, Nam-Ho Kim, Ho-Kyew Choi, Jeong Kug Lee, Hae Jin Rhee, Sung-Oh Hu. Lysophosphatidic acid induces upregulation of Mcl-1 and protects apoptosis in a PTX-dependent manner in H19-7 cells. Cellular signalling. vol 22. issue 3. 2010-03-08. PMID:19913093. |
to explore how lpa regulates cell survival or apoptosis in a developing neuron, mechanisms for cell survival and signaling cascades by lpa were investigated in h19-7 hippocampal progenitor cells. |
2010-03-08 |
2023-08-12 |
Not clear |
| Xia Chen, Qi Zhang, Qiong Cheng, Fei Din. Protective effect of salidroside against H2O2-induced cell apoptosis in primary culture of rat hippocampal neurons. Molecular and cellular biochemistry. vol 332. issue 1-2. 2010-03-04. PMID:19554425. |
protective effect of salidroside against h2o2-induced cell apoptosis in primary culture of rat hippocampal neurons. |
2010-03-04 |
2023-08-12 |
rat |