| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Penny Clarke, J David Beckham, J Smith Leser, Cristen C Hoyt, Kenneth L Tyle. Fas-mediated apoptotic signaling in the mouse brain following reovirus infection. Journal of virology. vol 83. issue 12. 2009-05-28. PMID:19321603. |
caspase 8, the initiator caspase associated with fas-mediated apoptosis, is activated in the cortex and hippocampal regions of both t3d- and t3a-infected mice. |
2009-05-28 |
2023-08-12 |
mouse |
| Matthias D Sury, Claudia Agarinis, Hans-Rudolf Widmer, Stephen L Leib, Stephan Christe. JNK is activated but does not mediate hippocampal neuronal apoptosis in experimental neonatal pneumococcal meningitis. Neurobiology of disease. vol 32. issue 1. 2009-05-21. PMID:18703144. |
jnk is activated but does not mediate hippocampal neuronal apoptosis in experimental neonatal pneumococcal meningitis. |
2009-05-21 |
2023-08-12 |
rat |
| Matthias D Sury, Claudia Agarinis, Hans-Rudolf Widmer, Stephen L Leib, Stephan Christe. JNK is activated but does not mediate hippocampal neuronal apoptosis in experimental neonatal pneumococcal meningitis. Neurobiology of disease. vol 32. issue 1. 2009-05-21. PMID:18703144. |
pneumococcal meningitis is associated with caspase 3-dependent apoptosis of recently post-mitotic immature neurons in the dentate gyrus of the hippocampus. |
2009-05-21 |
2023-08-12 |
rat |
| Matthias D Sury, Claudia Agarinis, Hans-Rudolf Widmer, Stephen L Leib, Stephan Christe. JNK is activated but does not mediate hippocampal neuronal apoptosis in experimental neonatal pneumococcal meningitis. Neurobiology of disease. vol 32. issue 1. 2009-05-21. PMID:18703144. |
however, whether jnk is involved in hippocampal apoptosis caused by pneumococcal meningitis has so far not been investigated. |
2009-05-21 |
2023-08-12 |
rat |
| Matthias D Sury, Claudia Agarinis, Hans-Rudolf Widmer, Stephen L Leib, Stephan Christe. JNK is activated but does not mediate hippocampal neuronal apoptosis in experimental neonatal pneumococcal meningitis. Neurobiology of disease. vol 32. issue 1. 2009-05-21. PMID:18703144. |
these findings suggested that jnk may not be involved in pneumococcal meningitis-induced hippocampal apoptosis. |
2009-05-21 |
2023-08-12 |
rat |
| Matthias D Sury, Claudia Agarinis, Hans-Rudolf Widmer, Stephen L Leib, Stephan Christe. JNK is activated but does not mediate hippocampal neuronal apoptosis in experimental neonatal pneumococcal meningitis. Neurobiology of disease. vol 32. issue 1. 2009-05-21. PMID:18703144. |
indeed, although intracerebroventricular administration of d-jnki-1 or as601245 (two highly specific jnk inhibitors) inhibited c-jun phosphorylation and protein expression in the hippocampus, hippocampal apoptosis was unaffected. |
2009-05-21 |
2023-08-12 |
rat |
| Matthias D Sury, Claudia Agarinis, Hans-Rudolf Widmer, Stephen L Leib, Stephan Christe. JNK is activated but does not mediate hippocampal neuronal apoptosis in experimental neonatal pneumococcal meningitis. Neurobiology of disease. vol 32. issue 1. 2009-05-21. PMID:18703144. |
collectively, these results demonstrate that jnk does not mediate hippocampal apoptosis in pneumococcal meningitis, and that jnk may be involved in processes unrelated to apoptosis in this disease. |
2009-05-21 |
2023-08-12 |
rat |
| Nan Sang, Li Hou, Yang Yun, Guangke L. SO(2) inhalation induces protein oxidation, DNA-protein crosslinks and apoptosis in rat hippocampus. Ecotoxicology and environmental safety. vol 72. issue 3. 2009-05-07. PMID:18722661. |
so(2) inhalation induces protein oxidation, dna-protein crosslinks and apoptosis in rat hippocampus. |
2009-05-07 |
2023-08-12 |
rat |
| Nan Sang, Li Hou, Yang Yun, Guangke L. SO(2) inhalation induces protein oxidation, DNA-protein crosslinks and apoptosis in rat hippocampus. Ecotoxicology and environmental safety. vol 72. issue 3. 2009-05-07. PMID:18722661. |
in the present study, so(2) inhalation-induced effects on the protein oxidation, dna-protein crosslinks and apoptosis in rat hippocampus were studied, by exposing wistar rats to so(2) at 14, 28 and 56mg/m(3). |
2009-05-07 |
2023-08-12 |
rat |
| Il-Gyu Ko, Mal-Soon Shin, Bo-Kyun Kim, Sung-Eun Kim, Yun-Hee Sung, Tae-Soo Kim, Min-Chul Shin, Han-Jin Cho, Sin-Chul Kim, Sang-Hoon Kim, Khae-Hawn Kim, Dong-Hoon Shin, Chang-Ju Ki. Tadalafil improves short-term memory by suppressing ischemia-induced apoptosis of hippocampal neuronal cells in gerbils. Pharmacology, biochemistry, and behavior. vol 91. issue 4. 2009-04-23. PMID:19010346. |
tadalafil improves short-term memory by suppressing ischemia-induced apoptosis of hippocampal neuronal cells in gerbils. |
2009-04-23 |
2023-08-12 |
Not clear |
| Dalma Ménesi, Klára Kitajka, Eszter Molnár, Zoltán Kis, Jérome Belleger, Michael Narce, Jing X Kang, László G Puskás, Undurti N Da. Gene and protein expression profiling of the fat-1 mouse brain. Prostaglandins, leukotrienes, and essential fatty acids. vol 80. issue 1. 2009-04-17. PMID:19138887. |
gene expression profile, rt-pcr and protein microarray studies in the hippocampus and whole brain of wild-type and fat-1 transgenic mice revealed that genes and proteins concerned with inflammation, apoptosis, neurotransmission, and neuronal growth and synapse formation are specifically modulated in fat-1 mice. |
2009-04-17 |
2023-08-12 |
mouse |
| Zhong Dai, Jian Xiao, Si-Yu Liu, Liao Cui, Gao-Yun Hu, De-Jian Jian. Rutaecarpine inhibits hypoxia/reoxygenation-induced apoptosis in rat hippocampal neurons. Neuropharmacology. vol 55. issue 8. 2009-04-15. PMID:18809421. |
rutaecarpine inhibits hypoxia/reoxygenation-induced apoptosis in rat hippocampal neurons. |
2009-04-15 |
2023-08-12 |
rat |
| Zhong Dai, Jian Xiao, Si-Yu Liu, Liao Cui, Gao-Yun Hu, De-Jian Jian. Rutaecarpine inhibits hypoxia/reoxygenation-induced apoptosis in rat hippocampal neurons. Neuropharmacology. vol 55. issue 8. 2009-04-15. PMID:18809421. |
the present study was to investigate the effect of rut on hypoxia/reoxygenation (h/r)-induced apoptosis in primary rat hippocampal neurons. |
2009-04-15 |
2023-08-12 |
rat |
| Zhong Dai, Jian Xiao, Si-Yu Liu, Liao Cui, Gao-Yun Hu, De-Jian Jian. Rutaecarpine inhibits hypoxia/reoxygenation-induced apoptosis in rat hippocampal neurons. Neuropharmacology. vol 55. issue 8. 2009-04-15. PMID:18809421. |
in summary, the present data suggest that rut inhibits h/r-induced apoptosis of hippocampal neurons via trpv1-[ca2+]i-dependent and pi3k/akt signaling pathway, which is related to inhibiting oxidative stress and caspase-3 activation. |
2009-04-15 |
2023-08-12 |
rat |
| Tong Wang, Cun-Zhi Liu, Jian-Chun Yu, Wen Jiang, Jing-Xian Ha. Acupuncture protected cerebral multi-infarction rats from memory impairment by regulating the expression of apoptosis related genes Bcl-2 and Bax in hippocampus. Physiology & behavior. vol 96. issue 1. 2009-04-15. PMID:18938189. |
acupuncture protected cerebral multi-infarction rats from memory impairment by regulating the expression of apoptosis related genes bcl-2 and bax in hippocampus. |
2009-04-15 |
2023-08-12 |
rat |
| Tong Wang, Cun-Zhi Liu, Jian-Chun Yu, Wen Jiang, Jing-Xian Ha. Acupuncture protected cerebral multi-infarction rats from memory impairment by regulating the expression of apoptosis related genes Bcl-2 and Bax in hippocampus. Physiology & behavior. vol 96. issue 1. 2009-04-15. PMID:18938189. |
in this paper, we observed the effect of acupuncture on memory impairment, apoptosis and expression of bcl-2 and bax in hippocampus of cerebral multi-infarction rats. |
2009-04-15 |
2023-08-12 |
rat |
| Miao He, Lin Zhao, Min-Jie Wei, Wei-Fan Yao, Hai-Shan Zhao, Fu-Jun Che. Neuroprotective effects of (-)-epigallocatechin-3-gallate on aging mice induced by D-galactose. Biological & pharmaceutical bulletin. vol 32. issue 1. 2009-04-15. PMID:19122281. |
tdt-mediated dutp-biotin nick end labeling (tunel) staining method was used to detect neuronal apoptosis, and the activation and expression of proapoptotic protein caspase-3 in the hippocampus were observed and analyzed using immunohistochemical staining and the western blot method to evaluate apoptosis in the brain. |
2009-04-15 |
2023-08-12 |
mouse |
| Miao He, Lin Zhao, Min-Jie Wei, Wei-Fan Yao, Hai-Shan Zhao, Fu-Jun Che. Neuroprotective effects of (-)-epigallocatechin-3-gallate on aging mice induced by D-galactose. Biological & pharmaceutical bulletin. vol 32. issue 1. 2009-04-15. PMID:19122281. |
the results indicated that subcutaneous injection of d-gal induced learning and memory impairment in mice, decreased t-sod and gsh-px activities, increased mda contents in the hippocampus, and increased the cell apoptosis index and cleaved caspase-3 protein expression in the hippocampus. |
2009-04-15 |
2023-08-12 |
mouse |
| Miao He, Lin Zhao, Min-Jie Wei, Wei-Fan Yao, Hai-Shan Zhao, Fu-Jun Che. Neuroprotective effects of (-)-epigallocatechin-3-gallate on aging mice induced by D-galactose. Biological & pharmaceutical bulletin. vol 32. issue 1. 2009-04-15. PMID:19122281. |
oral administration of egcg (2 mg/kg or 6 mg/kg) for 4 weeks significantly improved the cognitive deficits in mice and elevated t-sod and gsh-px activities, decreased mda contents in the hippocampus, and reduced the cell apoptosis index and expression of cleaved caspase-3 in the mouse hippocampus. |
2009-04-15 |
2023-08-12 |
mouse |
| Jian-Hua Zhang, Simon J Fung, Mingchu Xi, Sharon Sampogna, Michael H Chas. Recurrent apnea induces neuronal apoptosis in the guinea pig forebrain. Experimental neurology. vol 216. issue 2. 2009-04-15. PMID:19124019. |
the present data indicate that recurrent apnea results in cell death in the hippocampus and related forebrain regions via mechanisms of apoptosis, which may represent the basis for the clinical complications of obstructive sleep apnea and sleep-disordered breathing. |
2009-04-15 |
2023-08-12 |
Not clear |