Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Wei Zhu, Honghua Zheng, Xinli Shao, Wei Wang, Qing Yao, Zhengli L. Excitotoxicity of TNFalpha derived from KA activated microglia on hippocampal neurons in vitro and in vivo. Journal of neurochemistry. vol 114. issue 2. 2010-08-23. PMID:20438614. |
we use electrophysiological techniques, elisa, western-blot, rt-pcr assay and tunel method to explore whether over-produced tumor necrosis factor alpha (tnfalpha) released from activated microglia results in neuronal injuries, and further causes apoptosis through increasing excitotoxicity of hippocampal neurons. |
2010-08-23 |
2023-08-12 |
rat |
Wei Zhu, Honghua Zheng, Xinli Shao, Wei Wang, Qing Yao, Zhengli L. Excitotoxicity of TNFalpha derived from KA activated microglia on hippocampal neurons in vitro and in vivo. Journal of neurochemistry. vol 114. issue 2. 2010-08-23. PMID:20438614. |
these studies suggest that tnfalpha derived from ka activated microglia increases excitotoxicity of hippocampal neurons, and might induce neuronal apoptosis in vitro and in vivo. |
2010-08-23 |
2023-08-12 |
rat |
Myoung-Sub Song, Joong-Sun Kim, Miyoung Yang, Sung-Ho Kim, Jong-Choon Kim, Soo Hyun Park, Taekyun Shin, Changjong Moo. Gamma-ray susceptibility of immature and mature hippocampal cultured cells. The Journal of veterinary medical science. vol 72. issue 5. 2010-08-20. PMID:20103993. |
in addition, gamma-irradiation may induce caspase-dependent apoptosis in immature hippocampal cells. |
2010-08-20 |
2023-08-12 |
rat |
Hui-guo Liu, Zhi-feng Zhang, Zhen-xiang Zhang, Yong-ping Gao, Ru-ji Ni. [The change and mechanism of apoptosis in the hippocampal CA1 region of rats exposed to intermittent hypoxia]. Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases. vol 30. issue 5. 2010-08-17. PMID:17651645. |
to investigate the effect of intermittent hypoxia on rat hippocampal oxidative stress and neuron apoptosis in the hippocampal ca1 region. |
2010-08-17 |
2023-08-12 |
rat |
Rong-guo Liu, Na Song, Jie-meng Li, Xiang Cui, Yan-qing Che. [Akt involved in diazoxide preconditioning against rat hippocampal neuronal apoptosis induced by anoxia-reoxygenation injury]. Zhonghua yi xue za zhi. vol 90. issue 7. 2010-08-17. PMID:20368077. |
[akt involved in diazoxide preconditioning against rat hippocampal neuronal apoptosis induced by anoxia-reoxygenation injury]. |
2010-08-17 |
2023-08-12 |
rat |
Carrie L Yochum, Prianka Bhattacharya, Laryssa Patti, Oleg Mirochnitchenko, George C Wagne. Animal model of autism using GSTM1 knockout mice and early post-natal sodium valproate treatment. Behavioural brain research. vol 210. issue 2. 2010-08-10. PMID:20178820. |
vpa treatment caused significant increases in apoptosis in granule cells of the hippocampus and cerebellum. |
2010-08-10 |
2023-08-12 |
mouse |
Carrie L Yochum, Prianka Bhattacharya, Laryssa Patti, Oleg Mirochnitchenko, George C Wagne. Animal model of autism using GSTM1 knockout mice and early post-natal sodium valproate treatment. Behavioural brain research. vol 210. issue 2. 2010-08-10. PMID:20178820. |
collectively, these studies indicate that vpa-treatment causes cerebellar and hippocampal apoptosis and that having the wild-type gstm1 genotype may confer protection against vpa-induced neuronal death in female mice. |
2010-08-10 |
2023-08-12 |
mouse |
Maria-Leonor Lopez-Meraz, Jerome Niquet, Claude G Wasterlai. Distinct caspase pathways mediate necrosis and apoptosis in subpopulations of hippocampal neurons after status epilepticus. Epilepsia. vol 51 Suppl 3. 2010-08-03. PMID:20618402. |
distinct caspase pathways mediate necrosis and apoptosis in subpopulations of hippocampal neurons after status epilepticus. |
2010-08-03 |
2023-08-12 |
rat |
Andrew A Pieper, Shanhai Xie, Emanuela Capota, Sandi Jo Estill, Jeannie Zhong, Jeffrey M Long, Ginger L Becker, Paula Huntington, Shauna E Goldman, Ching-Han Shen, Maria Capota, Jeremiah K Britt, Tiina Kotti, Kerstin Ure, Daniel J Brat, Noelle S Williams, Karen S MacMillan, Jacinth Naidoo, Lisa Melito, Jenny Hsieh, Jef De Brabander, Joseph M Ready, Steven L McKnigh. Discovery of a proneurogenic, neuroprotective chemical. Cell. vol 142. issue 1. 2010-08-02. PMID:20603013. |
prolonged administration of p7c3 to npas3(-/-) mice corrected these deficits by normalizing levels of apoptosis of newborn hippocampal neurons. |
2010-08-02 |
2023-08-12 |
mouse |
Qiao Niu, Lin-ping Wang, Yi-lan Chen, Hong-mei Zhan. [Relationship between apoptosis of rat hippocampus cells induced by aluminum and the copy of the bcl-2 as well as bax mRNA]. Wei sheng yan jiu = Journal of hygiene research. vol 34. issue 6. 2010-07-29. PMID:16535832. |
[relationship between apoptosis of rat hippocampus cells induced by aluminum and the copy of the bcl-2 as well as bax mrna]. |
2010-07-29 |
2023-08-12 |
rat |
Qiao Niu, Lin-ping Wang, Yi-lan Chen, Hong-mei Zhan. [Relationship between apoptosis of rat hippocampus cells induced by aluminum and the copy of the bcl-2 as well as bax mRNA]. Wei sheng yan jiu = Journal of hygiene research. vol 34. issue 6. 2010-07-29. PMID:16535832. |
to explore the effects of aluminum chloride (alcl3) on the apoptosis of rat hippocampus cells and the relationship between the apoptosis and the expression of the bcl-2 as well as bax mrna. |
2010-07-29 |
2023-08-12 |
rat |
Yu-Qing Li, Isabelle Aubert, C Shun Won. Abrogation of early apoptosis does not alter late inhibition of hippocampal neurogenesis after irradiation. International journal of radiation oncology, biology, physics. vol 77. issue 4. 2010-07-27. PMID:20610042. |
abrogation of early apoptosis does not alter late inhibition of hippocampal neurogenesis after irradiation. |
2010-07-27 |
2023-08-12 |
Not clear |
Juan Perucho, Isabel Rubio, Maria J Casarejos, Ana Gomez, Jose A Rodriguez-Navarro, Rosa M Solano, Justo Garcia De Yébenes, Maria A Men. Anesthesia with isoflurane increases amyloid pathology in mice models of Alzheimer's disease. Journal of Alzheimer's disease : JAD. vol 19. issue 4. 2010-07-22. PMID:20308791. |
we have investigated the effects of repetitive anesthesia, twice a week, for 3 months, from 7 to 10 months of age, with isoflurane on survival, behavior, apoptosis in hippocampal cells, amyloid-beta (abeta) peptide and tau patterns, chaperones and autophagy in wt and abetapp{swe} mice. |
2010-07-22 |
2023-08-12 |
mouse |
J-Q Tian, Y Wang, N Lin, Y-J Guo, S-H Sun, D-J Zo. Active immunization with glucose-dependent insulinotropic polypeptide vaccine influences brain function and behaviour in rats. Scandinavian journal of immunology. vol 72. issue 1. 2010-07-21. PMID:20591069. |
data indicated that gip-klh-immunized rats showed decreased spontaneous activity in the open field test, decreased cerebral glucose utilization assessed by 18f-fluorodeoxyglucose-positron emission tomography/computed tomography (pet/ct), and increased apoptosis and proliferation of hippocampal granule cells marked by the terminal deoxynucleotidyl transferase-mediated dutp nick end labelling (tunel) or proliferating cell nuclear antigen method. |
2010-07-21 |
2023-08-12 |
rat |
Sung-Eun Kim, Il-Gyu Ko, Bo-Kyun Kim, Mal-Soon Shin, Sehyung Cho, Chang-Ju Kim, Sang-Hun Kim, Seung-Soo Baek, Eun-Kyu Lee, Yong-Seok Je. Treadmill exercise prevents aging-induced failure of memory through an increase in neurogenesis and suppression of apoptosis in rat hippocampus. Experimental gerontology. vol 45. issue 5. 2010-07-06. PMID:20156544. |
treadmill exercise prevents aging-induced failure of memory through an increase in neurogenesis and suppression of apoptosis in rat hippocampus. |
2010-07-06 |
2023-08-12 |
rat |
Sung-Eun Kim, Il-Gyu Ko, Bo-Kyun Kim, Mal-Soon Shin, Sehyung Cho, Chang-Ju Kim, Sang-Hun Kim, Seung-Soo Baek, Eun-Kyu Lee, Yong-Seok Je. Treadmill exercise prevents aging-induced failure of memory through an increase in neurogenesis and suppression of apoptosis in rat hippocampus. Experimental gerontology. vol 45. issue 5. 2010-07-06. PMID:20156544. |
apoptosis in the hippocampus also disturbs cognitive functions. |
2010-07-06 |
2023-08-12 |
rat |
Sung-Eun Kim, Il-Gyu Ko, Bo-Kyun Kim, Mal-Soon Shin, Sehyung Cho, Chang-Ju Kim, Sang-Hun Kim, Seung-Soo Baek, Eun-Kyu Lee, Yong-Seok Je. Treadmill exercise prevents aging-induced failure of memory through an increase in neurogenesis and suppression of apoptosis in rat hippocampus. Experimental gerontology. vol 45. issue 5. 2010-07-06. PMID:20156544. |
in this study, we examined the effect of treadmill exercise on memory in relation to neurogensis and apoptosis in the hippocampal dentate gyrus of old-aged rats. |
2010-07-06 |
2023-08-12 |
rat |
Sung-Eun Kim, Il-Gyu Ko, Bo-Kyun Kim, Mal-Soon Shin, Sehyung Cho, Chang-Ju Kim, Sang-Hun Kim, Seung-Soo Baek, Eun-Kyu Lee, Yong-Seok Je. Treadmill exercise prevents aging-induced failure of memory through an increase in neurogenesis and suppression of apoptosis in rat hippocampus. Experimental gerontology. vol 45. issue 5. 2010-07-06. PMID:20156544. |
the present results showed that loss of memory by aging was associated with a decrease in neurogenesis and an increase in apoptosis in the hippocampal dentate gyrus. |
2010-07-06 |
2023-08-12 |
rat |
Sung-Eun Kim, Il-Gyu Ko, Bo-Kyun Kim, Mal-Soon Shin, Sehyung Cho, Chang-Ju Kim, Sang-Hun Kim, Seung-Soo Baek, Eun-Kyu Lee, Yong-Seok Je. Treadmill exercise prevents aging-induced failure of memory through an increase in neurogenesis and suppression of apoptosis in rat hippocampus. Experimental gerontology. vol 45. issue 5. 2010-07-06. PMID:20156544. |
treadmill exercise improved short-term and spatial memories by enhancing neurogenesis and suppressing apoptosis in the hippocampal dentate gyrus of old-aged rats. |
2010-07-06 |
2023-08-12 |
rat |
Jicheng Liu, Chengchong Li, Guihua Xing, Li Zhou, Miaoxian Dong, Yutao Geng, Xueyan Li, Jiaming Li, Gang Wang, Dejia Zou, Yingcai Ni. Beta-asarone attenuates neuronal apoptosis induced by Beta amyloid in rat hippocampus. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. vol 130. issue 5. 2010-07-01. PMID:20460873. |
beta-asarone attenuates neuronal apoptosis induced by beta amyloid in rat hippocampus. |
2010-07-01 |
2023-08-12 |
rat |