Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Tamami Haraguchi, Katsunori Iwasaki, Kotaro Takasaki, Kanako Uchida, Tetsuya Naito, Ai Nogami, Kaori Kubota, Taro Shindo, Naoki Uchida, Shutaro Katsurabayashi, Kenichi Mishima, Ryoji Nishimura, Michihiro Fujiwar. Telmisartan, a partial agonist of peroxisome proliferator-activated receptor gamma, improves impairment of spatial memory and hippocampal apoptosis in rats treated with repeated cerebral ischemia. Brain research. vol 1353. 2010-12-20. PMID:20637184. |
telmisartan, a partial agonist of peroxisome proliferator-activated receptor gamma, improves impairment of spatial memory and hippocampal apoptosis in rats treated with repeated cerebral ischemia. |
2010-12-20 |
2023-08-12 |
rat |
Tamami Haraguchi, Katsunori Iwasaki, Kotaro Takasaki, Kanako Uchida, Tetsuya Naito, Ai Nogami, Kaori Kubota, Taro Shindo, Naoki Uchida, Shutaro Katsurabayashi, Kenichi Mishima, Ryoji Nishimura, Michihiro Fujiwar. Telmisartan, a partial agonist of peroxisome proliferator-activated receptor gamma, improves impairment of spatial memory and hippocampal apoptosis in rats treated with repeated cerebral ischemia. Brain research. vol 1353. 2010-12-20. PMID:20637184. |
repeated cerebral ischemia (ri: 10 min x 2) significantly induced impairment of spatial memory and hippocampal apoptosis in rats. |
2010-12-20 |
2023-08-12 |
rat |
Xiao Ming Li, Fang Han, Dong Juan Liu, Yu Xiu Sh. Single-prolonged stress induced mitochondrial-dependent apoptosis in hippocampus in the rat model of post-traumatic stress disorder. Journal of chemical neuroanatomy. vol 40. issue 3. 2010-12-10. PMID:20624456. |
single-prolonged stress induced mitochondrial-dependent apoptosis in hippocampus in the rat model of post-traumatic stress disorder. |
2010-12-10 |
2023-08-12 |
rat |
Xiao Ming Li, Fang Han, Dong Juan Liu, Yu Xiu Sh. Single-prolonged stress induced mitochondrial-dependent apoptosis in hippocampus in the rat model of post-traumatic stress disorder. Journal of chemical neuroanatomy. vol 40. issue 3. 2010-12-10. PMID:20624456. |
the aim of this study was to reveal the possible mechanisms involved in apoptosis induced by single-prolonged stress (sps) in hippocampus of ptsd rats. |
2010-12-10 |
2023-08-12 |
rat |
Xiao Ming Li, Fang Han, Dong Juan Liu, Yu Xiu Sh. Single-prolonged stress induced mitochondrial-dependent apoptosis in hippocampus in the rat model of post-traumatic stress disorder. Journal of chemical neuroanatomy. vol 40. issue 3. 2010-12-10. PMID:20624456. |
the results indicate that sps-induced apoptosis in hippocampus of ptsd rats, and the mitochondrial pathway was involved in the process of sps-induced apoptosis. |
2010-12-10 |
2023-08-12 |
rat |
T V Nguyen, A Jayaraman, A Quaglino, C J Pik. Androgens selectively protect against apoptosis in hippocampal neurones. Journal of neuroendocrinology. vol 22. issue 9. 2010-12-06. PMID:20561156. |
androgens selectively protect against apoptosis in hippocampal neurones. |
2010-12-06 |
2023-08-12 |
Not clear |
T V Nguyen, A Jayaraman, A Quaglino, C J Pik. Androgens selectively protect against apoptosis in hippocampal neurones. Journal of neuroendocrinology. vol 22. issue 9. 2010-12-06. PMID:20561156. |
pretreatment of hippocampal neurones with testosterone or dihydrotestosterone attenuated cell death induced by beta-amyloid, staurosporine and apoptosis activator ii, but none of the other insults. |
2010-12-06 |
2023-08-12 |
Not clear |
Qun Wang, Theodore J Kalogeris, Meifang Wang, Allan W Jones, Ronald J Korthui. Antecedent ethanol attenuates cerebral ischemia/reperfusion-induced leukocyte-endothelial adhesive interactions and delayed neuronal death: role of large conductance, Ca2+-activated K+ channels. Microcirculation (New York, N.Y. : 1994). vol 17. issue 6. 2010-12-06. PMID:20690981. |
the extent of dnd, apoptosis and glial activation in hippocampus were assessed four days after i/r. |
2010-12-06 |
2023-08-12 |
mouse |
Qun Wang, Theodore J Kalogeris, Meifang Wang, Allan W Jones, Ronald J Korthui. Antecedent ethanol attenuates cerebral ischemia/reperfusion-induced leukocyte-endothelial adhesive interactions and delayed neuronal death: role of large conductance, Ca2+-activated K+ channels. Microcirculation (New York, N.Y. : 1994). vol 17. issue 6. 2010-12-06. PMID:20690981. |
compared with sham, i/r elicited increases in lr and la in pial venules and dnd and apoptosis as well as glial activation in the hippocampus. |
2010-12-06 |
2023-08-12 |
mouse |
Hai-ping Wang, Xiao-long Deng, Guang-qian L. [Effects of edaravone on the expression of interleukin-1beta, nuclear factor-kappaB and neuron apoptosis in juvenile rat hippocampus after status convulsion]. Zhonghua er ke za zhi = Chinese journal of pediatrics. vol 47. issue 8. 2010-12-02. PMID:19951488. |
[effects of edaravone on the expression of interleukin-1beta, nuclear factor-kappab and neuron apoptosis in juvenile rat hippocampus after status convulsion]. |
2010-12-02 |
2023-08-12 |
rat |
Hai-ping Wang, Xiao-long Deng, Guang-qian L. [Effects of edaravone on the expression of interleukin-1beta, nuclear factor-kappaB and neuron apoptosis in juvenile rat hippocampus after status convulsion]. Zhonghua er ke za zhi = Chinese journal of pediatrics. vol 47. issue 8. 2010-12-02. PMID:19951488. |
to investigate the effect of edaravone on expression of interleukin-1beta (il-1beta), nuclear factor-kappab (nf-kappab) and neuron apoptosis in the juvenile rat hippocampus after status convulsion (sc). |
2010-12-02 |
2023-08-12 |
rat |
Iu V Lebid', V Ie Dosenko, H H Skyb. [Expression of proteasome subunits PSMB5 and PSMB9 mRNA in hippocampal neurons in experimental diabetes mellitus: link with apoptosis and necrosis]. Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994). vol 56. issue 4. 2010-11-30. PMID:20968039. |
[expression of proteasome subunits psmb5 and psmb9 mrna in hippocampal neurons in experimental diabetes mellitus: link with apoptosis and necrosis]. |
2010-11-30 |
2023-08-12 |
Not clear |
Iu V Lebid', V Ie Dosenko, H H Skyb. [Expression of proteasome subunits PSMB5 and PSMB9 mRNA in hippocampal neurons in experimental diabetes mellitus: link with apoptosis and necrosis]. Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994). vol 56. issue 4. 2010-11-30. PMID:20968039. |
the goal of this work was to investigate the expression of proteasome subunits psmb5 and psmb9 mrna in ca1, ca2 and ca3 areas of hippocampus in parallel with processes of cell death (apoptosis and necrosis) in development dynamics of streptozotocine-induced diabetes. |
2010-11-30 |
2023-08-12 |
Not clear |
Omar I Khan, Qian Zhao, Forrest Miller, Gregory L Holme. Interictal spikes in developing rats cause long-standing cognitive deficits. Neurobiology of disease. vol 39. issue 3. 2010-11-16. PMID:20452427. |
early-life interictal spikes resulted in impaired new cell formation and decreased cell counts in the hippocampus but did not cause an increase in apoptosis. |
2010-11-16 |
2023-08-12 |
rat |
Min Fu, Zhao-Hui Sun, Huan-Cong Zu. Neuroprotective effect of piperine on primarily cultured hippocampal neurons. Biological & pharmaceutical bulletin. vol 33. issue 4. 2010-11-12. PMID:20410592. |
moreover, pretreatment with pip expects protective effect on glutamate-induced decrease of cell viability and apoptosis of hippocampal neurons. |
2010-11-12 |
2023-08-12 |
rat |
Caroline L Bellac, Roney S Coimbra, Stephan Christen, Stephen L Lei. Inhibition of the kynurenine-NAD+ pathway leads to energy failure and exacerbates apoptosis in pneumococcal meningitis. Journal of neuropathology and experimental neurology. vol 69. issue 11. 2010-11-12. PMID:20940631. |
we previously demonstrated that in an infant rat model of pneumococcal meningitis, there is activation of the kynurenine (kyn) pathway in the hippocampus, and that there was a positive correlation between the concentration of 3-hydroxykynurenine and the extent of hippocampal apoptosis. |
2010-11-12 |
2023-08-12 |
rat |
Caroline L Bellac, Roney S Coimbra, Stephan Christen, Stephen L Lei. Inhibition of the kynurenine-NAD+ pathway leads to energy failure and exacerbates apoptosis in pneumococcal meningitis. Journal of neuropathology and experimental neurology. vol 69. issue 11. 2010-11-12. PMID:20940631. |
to clarify the role of the kyn pathway in the pathogenesis of hippocampal apoptosis in pneumococcal meningitis, we specifically inhibited 2 key enzymes of the kyn pathway and assessed hippocampal apoptosis, kyn pathway metabolites, and nicotinamide adenine dinucleotide (nad) concentrations by high-performance liquid chromatography. |
2010-11-12 |
2023-08-12 |
rat |
Caroline L Bellac, Roney S Coimbra, Stephan Christen, Stephen L Lei. Inhibition of the kynurenine-NAD+ pathway leads to energy failure and exacerbates apoptosis in pneumococcal meningitis. Journal of neuropathology and experimental neurology. vol 69. issue 11. 2010-11-12. PMID:20940631. |
pharmacological inhibition of kynurenine 3-hydroxylase and kynureninase led to decreased cellular nad levels and increased apoptosis in the hippocampus. |
2010-11-12 |
2023-08-12 |
rat |
Caroline L Bellac, Roney S Coimbra, Stephan Christen, Stephen L Lei. Inhibition of the kynurenine-NAD+ pathway leads to energy failure and exacerbates apoptosis in pneumococcal meningitis. Journal of neuropathology and experimental neurology. vol 69. issue 11. 2010-11-12. PMID:20940631. |
our data suggest that activation of the kyn pathway in pneumococcal meningitis is neuroprotective by compensating for an increased nad demand caused by infection and inflammation;this mechanism may prevent energy failure and apoptosis in the hippocampus. |
2010-11-12 |
2023-08-12 |
rat |
Hyun Ju Lee, Jong Kil Lee, Hyun Lee, Ji-woong Shin, Janet E Carter, Toshiro Sakamoto, Hee Kyung Jin, Jae-sung Ba. The therapeutic potential of human umbilical cord blood-derived mesenchymal stem cells in Alzheimer's disease. Neuroscience letters. vol 481. issue 1. 2010-11-08. PMID:20600610. |
we confirmed that hucb-mscs co-culture reduced the hippocampal apoptosis induced by abeta treatment. |
2010-11-08 |
2023-08-12 |
mouse |