| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Adam Legradi, Szilvia Varszegi, Csaba Szigeti, Karoly Guly. Adult rat hippocampal slices as in vitro models for neurodegeneration: Studies on cell viability and apoptotic processes. Brain research bulletin. vol 84. issue 1. 2011-04-11. PMID:21056637. |
the present data show that in adult hippocampal slices a large number of pyramidal cells initiate apoptotic processes as a result of irreparable damage sustained during slice preparation and culture maintenance, and support the notion that apoptosis is an integral part of the neurodegenerative processes not only in vivo but also in vitro. |
2011-04-11 |
2023-08-12 |
rat |
| Qian Xiao, Chao Wang, Junchang Li, Qian Hou, Jinghua Li, Jing Ma, Wen Wang, Zongren Wan. Ginkgolide B protects hippocampal neurons from apoptosis induced by beta-amyloid 25-35 partly via up-regulation of brain-derived neurotrophic factor. European journal of pharmacology. vol 647. issue 1-3. 2011-04-01. PMID:20709055. |
ginkgolide b protects hippocampal neurons from apoptosis induced by beta-amyloid 25-35 partly via up-regulation of brain-derived neurotrophic factor. |
2011-04-01 |
2023-08-12 |
Not clear |
| Qian Xiao, Chao Wang, Junchang Li, Qian Hou, Jinghua Li, Jing Ma, Wen Wang, Zongren Wan. Ginkgolide B protects hippocampal neurons from apoptosis induced by beta-amyloid 25-35 partly via up-regulation of brain-derived neurotrophic factor. European journal of pharmacology. vol 647. issue 1-3. 2011-04-01. PMID:20709055. |
this study aims at investigating the neuroprotective effects of ginkgolide b against aβ25-35-induced apoptosis in cultured hippocampal neurons, and further exploring the possible mechanisms concerned. |
2011-04-01 |
2023-08-12 |
Not clear |
| Qian Xiao, Chao Wang, Junchang Li, Qian Hou, Jinghua Li, Jing Ma, Wen Wang, Zongren Wan. Ginkgolide B protects hippocampal neurons from apoptosis induced by beta-amyloid 25-35 partly via up-regulation of brain-derived neurotrophic factor. European journal of pharmacology. vol 647. issue 1-3. 2011-04-01. PMID:20709055. |
we first conducted the study of the aβ25-35-induced apoptosis characterized by the changes in cell viability, morphology, extracellular k(+) concentration, lactate dehydrogenase level, and the caspase-3 activity in hippocampal neurons. |
2011-04-01 |
2023-08-12 |
Not clear |
| Takuya Kaminuma, Yoshiyuki Suzuki, Katsuyuki Shirai, Toshiyuki Mizui, Shin-ei Noda, Yukari Yoshida, Tomoo Funayama, Takeo Takahashi, Yasuhiko Kobayashi, Tomoaki Shirao, Takashi Nakan. Effectiveness of carbon-ion beams for apoptosis induction in rat primary immature hippocampal neurons. Journal of radiation research. vol 51. issue 6. 2011-03-24. PMID:20940520. |
effectiveness of carbon-ion beams for apoptosis induction in rat primary immature hippocampal neurons. |
2011-03-24 |
2023-08-12 |
rat |
| Takuya Kaminuma, Yoshiyuki Suzuki, Katsuyuki Shirai, Toshiyuki Mizui, Shin-ei Noda, Yukari Yoshida, Tomoo Funayama, Takeo Takahashi, Yasuhiko Kobayashi, Tomoaki Shirao, Takashi Nakan. Effectiveness of carbon-ion beams for apoptosis induction in rat primary immature hippocampal neurons. Journal of radiation research. vol 51. issue 6. 2011-03-24. PMID:20940520. |
the apoptosis of hippocampal neurons increased in a dose-dependent manner following both x-ray and carbon-ion beams irradiation. |
2011-03-24 |
2023-08-12 |
rat |
| Takuya Kaminuma, Yoshiyuki Suzuki, Katsuyuki Shirai, Toshiyuki Mizui, Shin-ei Noda, Yukari Yoshida, Tomoo Funayama, Takeo Takahashi, Yasuhiko Kobayashi, Tomoaki Shirao, Takashi Nakan. Effectiveness of carbon-ion beams for apoptosis induction in rat primary immature hippocampal neurons. Journal of radiation research. vol 51. issue 6. 2011-03-24. PMID:20940520. |
carbon-ion beams were about 10-fold more effective than x-rays for apoptosis induction in immature hippocampal neurons. |
2011-03-24 |
2023-08-12 |
rat |
| Ji Hyun Choi, A Young Choi, Hana Yoon, Wonchae Choe, Kyung-Sik Yoon, Joohun Ha, Eui-Ju Yeo, Insug Kan. Baicalein protects HT22 murine hippocampal neuronal cells against endoplasmic reticulum stress-induced apoptosis through inhibition of reactive oxygen species production and CHOP induction. Experimental & molecular medicine. vol 42. issue 12. 2011-03-23. PMID:20959717. |
baicalein protects ht22 murine hippocampal neuronal cells against endoplasmic reticulum stress-induced apoptosis through inhibition of reactive oxygen species production and chop induction. |
2011-03-23 |
2023-08-12 |
mouse |
| Truong L X Nguyen, Chung Kwon Kim, Jun-Hee Cho, Kyung-Hoon Lee, Jee-Yin Ah. Neuroprotection signaling pathway of nerve growth factor and brain-derived neurotrophic factor against staurosporine induced apoptosis in hippocampal H19-7/IGF-IR [corrected]. Experimental & molecular medicine. vol 42. issue 8. 2011-03-14. PMID:20644345. |
neuroprotection signaling pathway of nerve growth factor and brain-derived neurotrophic factor against staurosporine induced apoptosis in hippocampal h19-7/igf-ir [corrected]. |
2011-03-14 |
2023-08-12 |
Not clear |
| Truong L X Nguyen, Chung Kwon Kim, Jun-Hee Cho, Kyung-Hoon Lee, Jee-Yin Ah. Neuroprotection signaling pathway of nerve growth factor and brain-derived neurotrophic factor against staurosporine induced apoptosis in hippocampal H19-7/IGF-IR [corrected]. Experimental & molecular medicine. vol 42. issue 8. 2011-03-14. PMID:20644345. |
here we report that activation of the phosphatidyl inositol 3 kinase (pi3k)/akt pathway is critical for protection of hippocampal cells from staurosporine (sts) induced apoptosis, characterized by nuclear condensation and activation of the caspase cascade. |
2011-03-14 |
2023-08-12 |
Not clear |
| b' M V Llorens-Mart\\xc3\\xadn, N Rueda, G S Tejeda, J Fl\\xc3\\xb3rez, J L Trejo, C Mart\\xc3\\xadnez-Cu\\xc3\\xa. Effects of voluntary physical exercise on adult hippocampal neurogenesis and behavior of Ts65Dn mice, a model of Down syndrome. Neuroscience. vol 171. issue 4. 2011-03-10. PMID:20875841.' |
10-12 month-old male ts and control (co) mice were submitted to voluntary physical exercise for 7 weeks and the effects of this protocol on hippocampal morphology, neurogenesis and apoptosis were evaluated. |
2011-03-10 |
2023-08-12 |
mouse |
| Hongmei Shen, Ying Yuan, Fei Ding, Jie Liu, Xiaosong G. The protective effects of Achyranthes bidentata polypeptides against NMDA-induced cell apoptosis in cultured hippocampal neurons through differential modulation of NR2A- and NR2B-containing NMDA receptors. Brain research bulletin. vol 77. issue 5. 2011-03-03. PMID:18765272. |
the protective effects of achyranthes bidentata polypeptides against nmda-induced cell apoptosis in cultured hippocampal neurons through differential modulation of nr2a- and nr2b-containing nmda receptors. |
2011-03-03 |
2023-08-12 |
rat |
| Hongmei Shen, Ying Yuan, Fei Ding, Jie Liu, Xiaosong G. The protective effects of Achyranthes bidentata polypeptides against NMDA-induced cell apoptosis in cultured hippocampal neurons through differential modulation of NR2A- and NR2B-containing NMDA receptors. Brain research bulletin. vol 77. issue 5. 2011-03-03. PMID:18765272. |
in this study, the neuroprotective effect of abpp against n-methyl-d-aspartate (nmda)-induced cell apoptosis was investigated in cultured rat hippocampal neurons. |
2011-03-03 |
2023-08-12 |
rat |
| Michelle E Schober, Benjamin Block, Joanna C Beachy, Kimberly D Statler, Christopher C Giza, Robert H Lan. Early and sustained increase in the expression of hippocampal IGF-1, but not EPO, in a developmental rodent model of traumatic brain injury. Journal of neurotrauma. vol 27. issue 11. 2011-03-03. PMID:20822461. |
we used the controlled cortical impact (cci) model and measured hippocampal mrna levels of epo, igf-1, epor, igf-1r, and markers of caspase-dependent apoptosis (bcl2, bax, and p53) at post-injury days (pid) 1, 2, 3, 7, and 14. |
2011-03-03 |
2023-08-12 |
rat |
| Jiaming Li, Gang Wang, Jicheng Liu, Li Zhou, Miaoxian Dong, Rui Wang, Xueyan Li, Xiaoming Li, Chunrong Lin, Yingcai Ni. Puerarin attenuates amyloid-beta-induced cognitive impairment through suppression of apoptosis in rat hippocampus in vivo. European journal of pharmacology. vol 649. issue 1-3. 2011-03-03. PMID:20868658. |
puerarin attenuates amyloid-beta-induced cognitive impairment through suppression of apoptosis in rat hippocampus in vivo. |
2011-03-03 |
2023-08-12 |
rat |
| Jiaming Li, Gang Wang, Jicheng Liu, Li Zhou, Miaoxian Dong, Rui Wang, Xueyan Li, Xiaoming Li, Chunrong Lin, Yingcai Ni. Puerarin attenuates amyloid-beta-induced cognitive impairment through suppression of apoptosis in rat hippocampus in vivo. European journal of pharmacology. vol 649. issue 1-3. 2011-03-03. PMID:20868658. |
the results show the intrahippocampal injection of aβ induced a spatial memory deficit, apoptosis, and caspase-9 activation in hippocampal neurons. |
2011-03-03 |
2023-08-12 |
rat |
| Jiaming Li, Gang Wang, Jicheng Liu, Li Zhou, Miaoxian Dong, Rui Wang, Xueyan Li, Xiaoming Li, Chunrong Lin, Yingcai Ni. Puerarin attenuates amyloid-beta-induced cognitive impairment through suppression of apoptosis in rat hippocampus in vivo. European journal of pharmacology. vol 649. issue 1-3. 2011-03-03. PMID:20868658. |
puerarin treatment ameliorated aβ(1-42)-induced cognitive impairment and reversed the increase of apoptosis in the hippocampus. |
2011-03-03 |
2023-08-12 |
rat |
| Wei Dai, Wei-Dong Li, Jun L. [Effect of electroacupuncture on hippocampal apoptosis and JNK signal pathway in chronic stress depression rats]. Zhen ci yan jiu = Acupuncture research. vol 35. issue 5. 2011-02-24. PMID:21235059. |
[effect of electroacupuncture on hippocampal apoptosis and jnk signal pathway in chronic stress depression rats]. |
2011-02-24 |
2023-08-12 |
rat |
| Wei Dai, Wei-Dong Li, Jun L. [Effect of electroacupuncture on hippocampal apoptosis and JNK signal pathway in chronic stress depression rats]. Zhen ci yan jiu = Acupuncture research. vol 35. issue 5. 2011-02-24. PMID:21235059. |
to observe the effect of electroacupuncture (ea) on hippocampal apoptosis and c-jun n-terminal kinase (jnk) signal pathway in chronic stress depression rats so as to study its mechanism underlying acupuncture-induced improvement of depression. |
2011-02-24 |
2023-08-12 |
rat |
| Zhian Liu, Weiwei Zhao, Tiejun Xu, Dongsheng Pei, Yuwen Pen. Alterations of NMDA receptor subunits NR1, NR2A and NR2B mRNA expression and their relationship to apoptosis following transient forebrain ischemia. Brain research. vol 1361. 2011-02-23. PMID:20850419. |
in this study, we applied in situ hybridization and tunel staining to investigate the expression of nmda receptor subunit mrna and apoptosis in hippocampus of rats after transient forebrain ischemia. |
2011-02-23 |
2023-08-12 |
rat |