| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Junhao Yan, Li Li, Nikan H Khatibi, Lei Yang, Ke Wang, Weiguang Zhang, Robert D Martin, Jingyan Han, John Zhang, Changman Zho. Blood-brain barrier disruption following subarchnoid hemorrhage may be faciliated through PUMA induction of endothelial cell apoptosis from the endoplasmic reticulum. Experimental neurology. vol 230. issue 2. 2011-08-15. PMID:21586287. |
immunohistochemical staining and western blot analysis demonstrated an increased expression of puma, bax, bak, grp78 and drp1 in the microvascular endothelial cells of the hippocampus, which was accompanied with endothelium apoptosis. |
2011-08-15 |
2023-08-12 |
rat |
| Guo-Hua Wang, Xiang-Gen Zhang, Zheng-Lin Jiang, Xia Li, Liang-Liang Peng, Yong-Cai Li, Yong Wan. Neuroprotective effects of hyperbaric oxygen treatment on traumatic brain injury in the rat. Journal of neurotrauma. vol 27. issue 9. 2011-08-08. PMID:20568957. |
neurological behavior score, brain water content, neuronal loss in the hippocampus, and cell apoptosis in brain tissue surrounding the primary injury site were examined to determine brain damage severity. |
2011-08-08 |
2023-08-12 |
rat |
| Xiao-Jun Cai, Hui-Qin Xu, Yi L. C-peptide and diabetic encephalopathy. Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih. vol 26. issue 2. 2011-08-04. PMID:21703121. |
administration of c-peptide partially improves the condition of the igf system in the brain and prevents neuronal apoptosis in the hippocampus of diabetic patients. |
2011-08-04 |
2023-08-12 |
Not clear |
| Ting Yang, Lei Zhuang, Niccolò Terrando, Xinmin Wu, Mark R Jonhson, Mervyn Maze, Daqing M. A clinically relevant model of perinatal global ischemic brain damage in rats. Brain research. vol 1383. 2011-08-02. PMID:21281606. |
apoptosis was increased with the duration of hypoxia with neuronal loss and cell shrinkage in the ca1 of hippocampus. |
2011-08-02 |
2023-08-12 |
rat |
| Jian-Lin Shao, Xiao-Hong Wan, Yan Chen, Chun Bi, Hong-Mei Chen, Ying Zhong, Xin-Hua Heng, Jin-Qiao Qia. H2S protects hippocampal neurons from anoxia-reoxygenation through cAMP-mediated PI3K/Akt/p70S6K cell-survival signaling pathways. Journal of molecular neuroscience : MN. vol 43. issue 3. 2011-07-21. PMID:20967511. |
h(2)s acted via camp-mediated pi3k/akt/p70s6k signal transduction pathways to inhibit hippocampal neuronal apoptosis and protect neurons from ogd/r-induced injury. |
2011-07-21 |
2023-08-12 |
rat |
| Margarita C Dinamarca, Juan P Sagal, Rodrigo A Quintanilla, Juan A Godoy, Macarena S Arrázola, Nibaldo C Inestros. Amyloid-beta-Acetylcholinesterase complexes potentiate neurodegenerative changes induced by the Abeta peptide. Implications for the pathogenesis of Alzheimer's disease. Molecular neurodegeneration. vol 5. 2011-07-14. PMID:20205793. |
we report here that treatment of rat hippocampal neurons with abeta-acetylcholinesterase (abeta-ache) complexes induced neurite network dystrophia and apoptosis. |
2011-07-14 |
2023-08-12 |
rat |
| Hiroya Sato, Takeyuki Takahashi, Kazumi Sumitani, Hirokatsu Takatsu, Shiro Uran. Glucocorticoid Generates ROS to Induce Oxidative Injury in the Hippocampus, Leading to Impairment of Cognitive Function of Rats. Journal of clinical biochemistry and nutrition. vol 47. issue 3. 2011-07-14. PMID:21103031. |
furthermore, pyramidal cell apoptosis was observed to accompany the loss of glucocorticoid receptors at the cornus ammonis 1 region of the hippocampus. |
2011-07-14 |
2023-08-12 |
rat |
| Zhi-bin Liu, Wen-min Niu, Xiao-bang Yang, Xiao-mei Niu, Wang Yua. [Effect of "Xiusanzhen"on expression of hippocampal Bcl-2 and Bax proteins in Alzheimer disease rats]. Zhen ci yan jiu = Acupuncture research. vol 36. issue 1. 2011-07-12. PMID:21585051. |
to observe the effect of electroacupuncture (ea) of "xiusanzhen" [3 acupoints, i.e., bilateral "yingxiang" (li 20) and "yintang" (ex-hn 3)] on expression of b-cell lymphoma/leukemia-2 (bcl-2, an antiapoptosis protein) and bax (a protein for promoting apoptosis) in the hippocampus in alzheimer disease (ad) rats, so as to explore its clinical mechanisms underlying relieving ad. |
2011-07-12 |
2023-08-12 |
rat |
| Cornelia Blaser, Matthias Wittwer, Denis Grandgirard, Stephen L Lei. Adjunctive dexamethasone affects the expression of genes related to inflammation, neurogenesis and apoptosis in infant rat pneumococcal meningitis. PloS one. vol 6. issue 3. 2011-07-05. PMID:21412436. |
separately for the cortex and the hippocampus, gene ontology analysis identified clusters of biological processes which were assigned to the predefined categories "inflammation", "growth", "apoptosis" and others. |
2011-07-05 |
2023-08-12 |
rat |
| Fei Yin, Jianhui Liu, Xuxu Zheng, Lixia Guo, He Xia. Geniposide induces the expression of heme oxygenase-1 via PI3K/Nrf2-signaling to enhance the antioxidant capacity in primary hippocampal neurons. Biological & pharmaceutical bulletin. vol 33. issue 11. 2011-06-29. PMID:21048309. |
in this study, geniposide upregulates the expression of heme oxygenase-1 (ho-1) to attenuate the cell apoptosis induced by 3-morpholinosydnonimine hydrochloride (sin-1) in primary cultured hippocampal neurons. |
2011-06-29 |
2023-08-12 |
Not clear |
| Karin van der Borght, Rickard Köhnke, Nathanael Göransson, Tomas Deierborg, Patrik Brundin, Charlotte Erlanson-Albertsson, Andreas Lindqvis. Reduced neurogenesis in the rat hippocampus following high fructose consumption. Regulatory peptides. vol 167. issue 1. 2011-06-29. PMID:21115071. |
this reduction in hippocampal neurogenesis was accompanied by increased apoptosis in the hippocampus and increased circulating levels of tnf-α. |
2011-06-29 |
2023-08-12 |
rat |
| Karin van der Borght, Rickard Köhnke, Nathanael Göransson, Tomas Deierborg, Patrik Brundin, Charlotte Erlanson-Albertsson, Andreas Lindqvis. Reduced neurogenesis in the rat hippocampus following high fructose consumption. Regulatory peptides. vol 167. issue 1. 2011-06-29. PMID:21115071. |
therefore, we hypothesize that the reduction in hippocampal neurogenesis may be due to the increased apoptosis induced by tnf-α. |
2011-06-29 |
2023-08-12 |
rat |
| Mark L Dallas, John P Boyle, Carol J Milligan, Rachael Sayer, Talitha L Kerrigan, Connor McKinstry, Peiyuan Lu, Jamel Mankouri, Mark Harris, Jason L Scragg, Hugh A Pearson, Chris Peer. Carbon monoxide protects against oxidant-induced apoptosis via inhibition of Kv2.1. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 25. issue 5. 2011-06-28. PMID:21248240. |
in hippocampal neurons, co selectively inhibits k(v)2.1, reverses the dramatic oxidant-induced increase in k(+) current density, and provides marked protection against oxidant-induced apoptosis. |
2011-06-28 |
2023-08-12 |
Not clear |
| X Chen, J Zhang, C Che. Endocannabinoid 2-arachidonoylglycerol protects neurons against β-amyloid insults. Neuroscience. vol 178. 2011-06-27. PMID:21256197. |
here, we demonstrate that exogenous application of 2-ag significantly protected hippocampal neurons in culture against aβ-induced neurodegeneration and apoptosis. |
2011-06-27 |
2023-08-12 |
Not clear |
| Hai-Ping Wang, Xiao-Long Deng, Guang-Qian L. [Effects of edaravone on glial fibrillary acidic protein and interleukin-lβ expression and neuronal apoptosis in juvenile rat hippocampus after status convulsion]. Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics. vol 13. issue 3. 2011-06-09. PMID:21426644. |
[effects of edaravone on glial fibrillary acidic protein and interleukin-lβ expression and neuronal apoptosis in juvenile rat hippocampus after status convulsion]. |
2011-06-09 |
2023-08-12 |
rat |
| Hai-Ping Wang, Xiao-Long Deng, Guang-Qian L. [Effects of edaravone on glial fibrillary acidic protein and interleukin-lβ expression and neuronal apoptosis in juvenile rat hippocampus after status convulsion]. Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics. vol 13. issue 3. 2011-06-09. PMID:21426644. |
to study the effects of edaravone on glial fibrillary acidic protein (gfap) and interleukin-1β (il-lβ) expression and neuronal apoptosis in the juvenile rat hippocampus after status convulsion (sc). |
2011-06-09 |
2023-08-12 |
rat |
| Sheng-Jia Zhang, Bettina Buchthal, David Lau, Stefanie Hayer, Oliver Dick, Markus Schwaninger, Roland Veltkamp, Ming Zou, Ursula Weiss, Hilmar Badin. A signaling cascade of nuclear calcium-CREB-ATF3 activated by synaptic NMDA receptors defines a gene repression module that protects against extrasynaptic NMDA receptor-induced neuronal cell death and ischemic brain damage. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 13. 2011-05-30. PMID:21451036. |
acting as a transcriptional repressor, atf3 protects cultured hippocampal neurons from apoptosis and extrasynaptic nmda receptor-induced cell death triggered by bath application of nmda or oxygen-glucose deprivation. |
2011-05-30 |
2023-08-12 |
mouse |
| Baojun Liu, Hongying Zhang, Changqing Xu, Guang Yang, Jiang Tao, Jianhua Huang, Jinfeng Wu, Xiaohong Duan, Yuxue Cao, Jingcheng Don. Neuroprotective effects of icariin on corticosterone-induced apoptosis in primary cultured rat hippocampal neurons. Brain research. vol 1375. 2011-05-23. PMID:21182828. |
neuroprotective effects of icariin on corticosterone-induced apoptosis in primary cultured rat hippocampal neurons. |
2011-05-23 |
2023-08-12 |
rat |
| Baojun Liu, Hongying Zhang, Changqing Xu, Guang Yang, Jiang Tao, Jianhua Huang, Jinfeng Wu, Xiaohong Duan, Yuxue Cao, Jingcheng Don. Neuroprotective effects of icariin on corticosterone-induced apoptosis in primary cultured rat hippocampal neurons. Brain research. vol 1375. 2011-05-23. PMID:21182828. |
in the present study the neuroprotective effects of icariin, an active natural ingredient from the chinese plant epimedium sagittatum maxim against corticosterone-induced apoptosis were examined in primary cultured rat hippocampal neuronal cells. |
2011-05-23 |
2023-08-12 |
rat |
| Baojun Liu, Hongying Zhang, Changqing Xu, Guang Yang, Jiang Tao, Jianhua Huang, Jinfeng Wu, Xiaohong Duan, Yuxue Cao, Jingcheng Don. Neuroprotective effects of icariin on corticosterone-induced apoptosis in primary cultured rat hippocampal neurons. Brain research. vol 1375. 2011-05-23. PMID:21182828. |
taken together, the present results suggest that the protective effects of icariin on apoptosis in hippocampal neuronal cells are potentially mediated through blockade of p38 mapk phosphorylation. |
2011-05-23 |
2023-08-12 |
rat |