Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Leinweih Andrew Tseng, John L Bixb. Interaction of an intracellular pentraxin with a BTB-Kelch protein is associated with ubiquitylation, aggregation and neuronal apoptosis. Molecular and cellular neurosciences. vol 47. issue 4. 2011-12-06. PMID:21549840. |
overexpression of npcd in hippocampal neurons led to cell death and apoptosis; this effect was exacerbated by klhl2 co-expression. |
2011-12-06 |
2023-08-12 |
Not clear |
D Filipović, J Zlatković, D Inta, I Bjelobaba, M Stojiljkovic, P Gas. Chronic isolation stress predisposes the frontal cortex but not the hippocampus to the potentially detrimental release of cytochrome c from mitochondria and the activation of caspase-3. Journal of neuroscience research. vol 89. issue 9. 2011-12-05. PMID:21656845. |
to define better the proapoptotic role of p53 under various stress conditions, we investigated the protein levels of p53 and cytochrome c in mitochondrial and cytosolic fractions, as well as caspase-3 activation and apoptosis, in the prefrontal cortex and hippocampus of male wistar rats subjected to acute, chronic, or combined stressors. |
2011-12-05 |
2023-08-12 |
rat |
Shuang Yu, Silei Yang, Florian Holsboer, Nuno Sousa, Osborne F X Almeid. Glucocorticoid regulation of astrocytic fate and function. PloS one. vol 6. issue 7. 2011-12-05. PMID:21811605. |
thus, unlike hippocampal granule neurons, astrocytes are resistant to gc-induced apoptosis; this resistance is due to lower production of reactive oxygen species (ros) and a greater buffering capacity against the cytotoxic actions of ros. |
2011-12-05 |
2023-08-12 |
rat |
Zhi-ying Hu, Jian-ying Huang, Ma-rong Fang, Jing Wang, Yan Li, Lin-zhen Wu, Ling Liu, Li Chen, Shu Ha. [Alterations of glial fibrillary acidic protein expression and neural apoptosis in brain of rat offspring born by cesarean section]. Zhonghua fu chan ke za zhi. vol 45. issue 11. 2011-11-28. PMID:21211284. |
to study changes of glial fibrillary acidic protein (gfap) expression and neural apoptosis in rat hippocampus and cortex of cesarean delivered offspring. |
2011-11-28 |
2023-08-12 |
rat |
Deepti Nair, Ehab A Dayyat, Shelley X Zhang, Yang Wang, David Goza. Intermittent hypoxia-induced cognitive deficits are mediated by NADPH oxidase activity in a murine model of sleep apnea. PloS one. vol 6. issue 5. 2011-11-28. PMID:21625437. |
in rodents, exposure to intermittent hypoxia (ih), a hallmark of obstructive sleep apnea (osa), is associated with neurobehavioral impairments, increased apoptosis in the hippocampus and cortex, as well as increased oxidant stress and inflammation. |
2011-11-28 |
2023-08-12 |
Not clear |
Bodo C Melni. Isotretinoin and FoxO1: A scientific hypothesis. Dermato-endocrinology. vol 3. issue 3. 2011-11-23. PMID:22110774. |
isotretinoin is regarded as a prodrug which after isomerizisation to all-trans-retinoic acid (atra) induces apoptosis in cells cultured from human sebaceous glands, meibomian glands, neuroblastoma cells, hypothalamic cells, hippocampus cells, dalton's lymphoma ascites cells, b16f-10 melanoma cells, and neuronal crest cells and others. |
2011-11-23 |
2023-08-12 |
human |
Ying Wu, You-liang Wen, Li D. [Effect of Shengmaisan on learning and memory abilities and hippocampal nitric oxide synthase expression and neuronal apoptosis in rats with vascular dementia]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University. vol 30. issue 6. 2011-11-22. PMID:20584669. |
[effect of shengmaisan on learning and memory abilities and hippocampal nitric oxide synthase expression and neuronal apoptosis in rats with vascular dementia]. |
2011-11-22 |
2023-08-12 |
rat |
Ying Wu, You-liang Wen, Li D. [Effect of Shengmaisan on learning and memory abilities and hippocampal nitric oxide synthase expression and neuronal apoptosis in rats with vascular dementia]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University. vol 30. issue 6. 2011-11-22. PMID:20584669. |
to observe the effect of shengmaisan on the learning and memory abilities and the expression of nitric oxide synthase and neuron apoptosis in the hippocampus of rats with vascular dementia (vd), and explore the mechanism of shengmaisan for treatment of vd. |
2011-11-22 |
2023-08-12 |
rat |
Junji Moriya, Rui Chen, Jun-ichi Yamakawa, Kenroh Sasaki, Yasuhito Ishigaki, Takashi Takahash. Resveratrol improves hippocampal atrophy in chronic fatigue mice by enhancing neurogenesis and inhibiting apoptosis of granular cells. Biological & pharmaceutical bulletin. vol 34. issue 3. 2011-11-22. PMID:21372384. |
resveratrol improves hippocampal atrophy in chronic fatigue mice by enhancing neurogenesis and inhibiting apoptosis of granular cells. |
2011-11-22 |
2023-08-12 |
mouse |
Junji Moriya, Rui Chen, Jun-ichi Yamakawa, Kenroh Sasaki, Yasuhito Ishigaki, Takashi Takahash. Resveratrol improves hippocampal atrophy in chronic fatigue mice by enhancing neurogenesis and inhibiting apoptosis of granular cells. Biological & pharmaceutical bulletin. vol 34. issue 3. 2011-11-22. PMID:21372384. |
furthermore, resveratrol inhibited neuronal apoptosis and expression of hippocampal acetylated p53 in the fatigue mice. |
2011-11-22 |
2023-08-12 |
mouse |
Junji Moriya, Rui Chen, Jun-ichi Yamakawa, Kenroh Sasaki, Yasuhito Ishigaki, Takashi Takahash. Resveratrol improves hippocampal atrophy in chronic fatigue mice by enhancing neurogenesis and inhibiting apoptosis of granular cells. Biological & pharmaceutical bulletin. vol 34. issue 3. 2011-11-22. PMID:21372384. |
resveratrol may be effective for improving fatigue symptoms and enlarging the atrophic hippocampus by repressing apoptosis and promoting neurogenesis. |
2011-11-22 |
2023-08-12 |
mouse |
Christopher A McPherson, Andrew D Kraft, G Jean Harr. Injury-induced neurogenesis: consideration of resident microglia as supportive of neural progenitor cells. Neurotoxicity research. vol 19. issue 2. 2011-11-09. PMID:20524106. |
we examined the induction of neurogenesis in the sgz at 72 h following an injection of the hippocampal toxicant, trimethyltin (tmt; 2 mg/kg, ip) inducing apoptosis in dentate granule neurons. |
2011-11-09 |
2023-08-12 |
mouse |
Guang-Qian Li, Hai-Ping Wang, Chun-Ming Jian. [Effects of edaravone on the expression of GRP78, Caspase-12, and neuron apoptosis in juvenile rat hippocampus after status convulsive]. Zhonghua er ke za zhi = Chinese journal of pediatrics. vol 49. issue 1. 2011-11-03. PMID:21429313. |
[effects of edaravone on the expression of grp78, caspase-12, and neuron apoptosis in juvenile rat hippocampus after status convulsive]. |
2011-11-03 |
2023-08-12 |
rat |
Guang-Qian Li, Hai-Ping Wang, Chun-Ming Jian. [Effects of edaravone on the expression of GRP78, Caspase-12, and neuron apoptosis in juvenile rat hippocampus after status convulsive]. Zhonghua er ke za zhi = Chinese journal of pediatrics. vol 49. issue 1. 2011-11-03. PMID:21429313. |
to observe the expression of grp78 (glucose regulated protein, grp78), caspase-12 and the change of neuron apoptosis in the juvenile rat hippocampus after status convulsive (sc), and to explore the effect of edaravone on them. |
2011-11-03 |
2023-08-12 |
rat |
Rikako Sanuki, Akishi Onishi, Chieko Koike, Rieko Muramatsu, Satoshi Watanabe, Yuki Muranishi, Shoichi Irie, Shinji Uneo, Toshiyuki Koyasu, Ryosuke Matsui, Yoan Chérasse, Yoshihiro Urade, Dai Watanabe, Mineo Kondo, Toshihide Yamashita, Takahisa Furukaw. miR-124a is required for hippocampal axogenesis and retinal cone survival through Lhx2 suppression. Nature neuroscience. vol 14. issue 9. 2011-10-24. PMID:21857657. |
we also observed that lhx2 downregulation by mir-124a is required for the prevention of apoptosis in the developing retina and proper axonal development of hippocampal neurons. |
2011-10-24 |
2023-08-12 |
mouse |
J Bustamante, S Lores-Arnaiz, S Tallis, D M Roselló, N Lago, A Lemberg, A Boveris, J C Perazz. Mitochondrial dysfunction as a mediator of hippocampal apoptosis in a model of hepatic encephalopathy. Molecular and cellular biochemistry. vol 354. issue 1-2. 2011-10-21. PMID:21505893. |
mitochondrial dysfunction as a mediator of hippocampal apoptosis in a model of hepatic encephalopathy. |
2011-10-21 |
2023-08-12 |
Not clear |
J Bustamante, S Lores-Arnaiz, S Tallis, D M Roselló, N Lago, A Lemberg, A Boveris, J C Perazz. Mitochondrial dysfunction as a mediator of hippocampal apoptosis in a model of hepatic encephalopathy. Molecular and cellular biochemistry. vol 354. issue 1-2. 2011-10-21. PMID:21505893. |
in this study, we describe the presence of apoptosis, associated with a mitochondrial dysfunction in the hippocampus of animals in an experimental model defined as minimal hepatic encephalopathy (mhe). |
2011-10-21 |
2023-08-12 |
Not clear |
J Bustamante, S Lores-Arnaiz, S Tallis, D M Roselló, N Lago, A Lemberg, A Boveris, J C Perazz. Mitochondrial dysfunction as a mediator of hippocampal apoptosis in a model of hepatic encephalopathy. Molecular and cellular biochemistry. vol 354. issue 1-2. 2011-10-21. PMID:21505893. |
the molecular mechanisms here proposed indicate the presence of apoptotic intrinsic pathways that point to hippocampal mitochondria as an important mediator of apoptosis in this experimental model. |
2011-10-21 |
2023-08-12 |
Not clear |
C A McPherson, M Aoyama, G J Harr. Interleukin (IL)-1 and IL-6 regulation of neural progenitor cell proliferation with hippocampal injury: differential regulatory pathways in the subgranular zone (SGZ) of the adolescent and mature mouse brain. Brain, behavior, and immunity. vol 25. issue 5. 2011-10-12. PMID:20833246. |
to produce acute apoptosis of hippocampal dentate granule cells. |
2011-10-12 |
2023-08-12 |
mouse |
Hao Li, Lin-lin Cai, Jian-gang Liu, Long-tao Liu, Jie Guan, Ming-fang Liu, Jia Hu, Yun We. Effect of early intervention with extract of Huannao Yicong Decoction (还脑益聪方) on the pathologic picture of hippocampus and neurocyte apoptosis in APP transgenic mice model of dementia. Chinese journal of integrative medicine. vol 17. issue 6. 2011-09-30. PMID:21660677. |
effect of early intervention with extract of huannao yicong decoction (还脑益聪方) on the pathologic picture of hippocampus and neurocyte apoptosis in app transgenic mice model of dementia. |
2011-09-30 |
2023-08-12 |
mouse |