| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zhaohui Liu, Li Gong, Xiaofang Li, Lin Ye, Bin Wang, Jing Liu, Jianyong Qiu, Huiduo Jiao, Wendong Zhang, Jingzao Chen, Jiuping Wan. Infrasound increases intracellular calcium concentration and induces apoptosis in hippocampi of adult rats. Molecular medicine reports. vol 5. issue 1. 2012-02-27. PMID:21946944. |
meanwhile, apoptosis in hippocampal neurons was found to increase on day 7 following 90 db spl infrasound exposure, and significantly increased on day 14. |
2012-02-27 |
2023-08-12 |
rat |
| Zhaohui Liu, Li Gong, Xiaofang Li, Lin Ye, Bin Wang, Jing Liu, Jianyong Qiu, Huiduo Jiao, Wendong Zhang, Jingzao Chen, Jiuping Wan. Infrasound increases intracellular calcium concentration and induces apoptosis in hippocampi of adult rats. Molecular medicine reports. vol 5. issue 1. 2012-02-27. PMID:21946944. |
these results demonstrate that a period of infrasonic exposure induced apoptosis and upregulated [ca²⁺]i levels in hippocampal neurons, suggesting that infrasound may cause damage to the central nervous system (cns) through the ca²⁺‑mediated apoptotic pathway in hippocampal neurons. |
2012-02-27 |
2023-08-12 |
rat |
| Kutay Deniz Atabay, Arzu Karaba. Pin1 inhibition activates cyclin D and produces neurodegenerative pathology. Journal of neurochemistry. vol 120. issue 3. 2012-02-24. PMID:21443524. |
here, we show that inhibition of pin1 by its selective inhibitor juglone leads to up-regulation of cyclind1, phospho-tau, and caspase 3, producing apoptosis in cultured rat hippocampal neurons. |
2012-02-24 |
2023-08-12 |
rat |
| Alexandra Heyden, Mihai-Constantin S Ionescu, Stefano Romorini, Bettina Kracht, Veronica Ghiglieri, Paolo Calabresi, Constanze Seidenbecher, Frank Angenstein, Eckart D Gundelfinge. Hippocampal enlargement in Bassoon-mutant mice is associated with enhanced neurogenesis, reduced apoptosis, and abnormal BDNF levels. Cell and tissue research. vol 346. issue 1. 2012-02-21. PMID:21935677. |
hippocampal enlargement in bassoon-mutant mice is associated with enhanced neurogenesis, reduced apoptosis, and abnormal bdnf levels. |
2012-02-21 |
2023-08-12 |
mouse |
| Alexandra Heyden, Mihai-Constantin S Ionescu, Stefano Romorini, Bettina Kracht, Veronica Ghiglieri, Paolo Calabresi, Constanze Seidenbecher, Frank Angenstein, Eckart D Gundelfinge. Hippocampal enlargement in Bassoon-mutant mice is associated with enhanced neurogenesis, reduced apoptosis, and abnormal BDNF levels. Cell and tissue research. vol 346. issue 1. 2012-02-21. PMID:21935677. |
these data show that hippocampal overgrowth in bassoon-mutant mice arises from a dysregulation of neurogenesis and apoptosis that might be associated with unbalanced bdnf levels. |
2012-02-21 |
2023-08-12 |
mouse |
| I Rondeau, S Picard, T M Bah, L Roy, R Godbout, G Roussea. Effects of different dietary ω-6/3 polyunsaturated fatty acids ratios on infarct size and the limbic system after myocardial infarction. Canadian journal of physiology and pharmacology. vol 89. issue 3. 2012-02-13. PMID:21423290. |
therefore, we hypothesized that a decrease in the dietary omega-6/3 pufa ratio, without altering the diet content in total fat, proteins, or carbohydrates, will result in a reduction of infarct size and a diminution of postreperfusion apoptosis observed in the amygdala and hippocampus. |
2012-02-13 |
2023-08-12 |
rat |
| I Rondeau, S Picard, T M Bah, L Roy, R Godbout, G Roussea. Effects of different dietary ω-6/3 polyunsaturated fatty acids ratios on infarct size and the limbic system after myocardial infarction. Canadian journal of physiology and pharmacology. vol 89. issue 3. 2012-02-13. PMID:21423290. |
apoptosis was evaluated in the hippocampus and the amygdala. |
2012-02-13 |
2023-08-12 |
rat |
| Qingsong Li, Shan Bian, Janet Hong, Yoko Kawase-Koga, Edwin Zhu, Yongri Zheng, Lizhuang Yang, Tao Su. Timing specific requirement of microRNA function is essential for embryonic and postnatal hippocampal development. PloS one. vol 6. issue 10. 2012-02-06. PMID:21991391. |
conditionally ablating the rnaase iii enzyme dicer at different embryonic time points utilizing three cre mouse lines causes abnormal hippocampal morphology and affects the number of hippocampal progenitors due to altered proliferation and increased apoptosis. |
2012-02-06 |
2023-08-12 |
mouse |
| Roberta Pennucci, Stefania Tavano, Diletta Tonoli, Sara Gualdoni, Ivan de Curti. Rac1 and Rac3 GTPases regulate the development of hilar mossy cells by affecting the migration of their precursors to the hilus. PloS one. vol 6. issue 9. 2012-01-30. PMID:21949760. |
we found that apoptosis was equally low in the hippocampus of both control and double knockout mice. |
2012-01-30 |
2023-08-12 |
mouse |
| Peter-Christian Klöhn, Michael Farmer, Jacqueline M Linehan, Catherine O'Malley, Mar Fernandez de Marco, William Taylor, Mark Farrow, Azy Khalili-Shirazi, Sebastian Brandner, John Colling. PrP antibodies do not trigger mouse hippocampal neuron apoptosis. Science (New York, N.Y.). vol 335. issue 6064. 2012-01-25. PMID:22223800. |
prp antibodies do not trigger mouse hippocampal neuron apoptosis. |
2012-01-25 |
2023-08-12 |
mouse |
| Marta Kubera, Ewa Obuchowicz, Lisa Goehler, Joanna Brzeszcz, Michael Mae. In animal models, psychosocial stress-induced (neuro)inflammation, apoptosis and reduced neurogenesis are associated to the onset of depression. Progress in neuro-psychopharmacology & biological psychiatry. vol 35. issue 3. 2012-01-06. PMID:20828592. |
the chronic mild stress (cms) and learned helplessness (lh) models show that depression-like behaviors are accompanied by peripheral and central inflammation, neuronal cell damage, decreased neurogenesis and apoptosis in the hippocampus. |
2012-01-06 |
2023-08-12 |
Not clear |
| Hai-peng Zhou, Ming-shan Wang, Fei Shi, Shi-long Ma, Hai-ou Li, Yan-lin Bi, Yu-qiu Liu, Hong Li. [Effects of acupuncture pre-conditioning on apoptosis in hippocampal neurons following ischemia-reperfusion injury in aged rats]. Zhonghua yi xue za zhi. vol 91. issue 17. 2012-01-05. PMID:21756776. |
[effects of acupuncture pre-conditioning on apoptosis in hippocampal neurons following ischemia-reperfusion injury in aged rats]. |
2012-01-05 |
2023-08-12 |
rat |
| Hai-peng Zhou, Ming-shan Wang, Fei Shi, Shi-long Ma, Hai-ou Li, Yan-lin Bi, Yu-qiu Liu, Hong Li. [Effects of acupuncture pre-conditioning on apoptosis in hippocampal neurons following ischemia-reperfusion injury in aged rats]. Zhonghua yi xue za zhi. vol 91. issue 17. 2012-01-05. PMID:21756776. |
to investigate the effects of acupuncture pre-conditioning on apoptosis in hippocampal neurons following ischemia-reperfusion injury in aged rats. |
2012-01-05 |
2023-08-12 |
rat |
| Kai Hu, Shu-Yu Li, Bo Xiao, Fang-fang Bi, Xiao-Qin Lu, Xiao-Mei W. Protective effects of quercetin against status epilepticus induced hippocampal neuronal injury in rats: involvement of X-linked inhibitor of apoptosis protein. Acta neurologica Belgica. vol 111. issue 3. 2012-01-04. PMID:22141284. |
protective effects of quercetin against status epilepticus induced hippocampal neuronal injury in rats: involvement of x-linked inhibitor of apoptosis protein. |
2012-01-04 |
2023-08-12 |
rat |
| Kai Hu, Shu-Yu Li, Bo Xiao, Fang-fang Bi, Xiao-Qin Lu, Xiao-Mei W. Protective effects of quercetin against status epilepticus induced hippocampal neuronal injury in rats: involvement of X-linked inhibitor of apoptosis protein. Acta neurologica Belgica. vol 111. issue 3. 2012-01-04. PMID:22141284. |
apoptosis and necrosis are two forms of neuronal death in post status epilepticus hippocampus, and the former has been widely studied and believed to be a major factor contributing to formation of abnormal excitatory circuit leading to refractory epileptic events. |
2012-01-04 |
2023-08-12 |
rat |
| Kai Hu, Shu-Yu Li, Bo Xiao, Fang-fang Bi, Xiao-Qin Lu, Xiao-Mei W. Protective effects of quercetin against status epilepticus induced hippocampal neuronal injury in rats: involvement of X-linked inhibitor of apoptosis protein. Acta neurologica Belgica. vol 111. issue 3. 2012-01-04. PMID:22141284. |
we investigated protective effects of quercetin on status epilepticus induced hippocampal neuronal injuries in rats and focused on two major proteins, the x-linked inhibitor of apoptosis protein, a key member of the inhibitor of apoptosis protein family, and the caspase-3 protein, a common effector for the execution-phase of cell signaling apoptotic pathways. |
2012-01-04 |
2023-08-12 |
rat |
| Kai Hu, Shu-Yu Li, Bo Xiao, Fang-fang Bi, Xiao-Qin Lu, Xiao-Mei W. Protective effects of quercetin against status epilepticus induced hippocampal neuronal injury in rats: involvement of X-linked inhibitor of apoptosis protein. Acta neurologica Belgica. vol 111. issue 3. 2012-01-04. PMID:22141284. |
we found expression alterations of x-linked inhibitor of apoptosis protein and caspase-3 protein in post status epilepticus hippocampus, along with an alteration in the number of apoptotic and surviving neurons. |
2012-01-04 |
2023-08-12 |
rat |
| Kai Hu, Shu-Yu Li, Bo Xiao, Fang-fang Bi, Xiao-Qin Lu, Xiao-Mei W. Protective effects of quercetin against status epilepticus induced hippocampal neuronal injury in rats: involvement of X-linked inhibitor of apoptosis protein. Acta neurologica Belgica. vol 111. issue 3. 2012-01-04. PMID:22141284. |
furthermore, quercetin treatment in rats undergoing status epilepticus led to an interventional effect on expression of x-linked inhibitor of apoptosis protein and the caspase-3 protein, with a corresponding positive change on the number of hippocampal apoptotic and surviving neurons. |
2012-01-04 |
2023-08-12 |
rat |
| Kai Hu, Shu-Yu Li, Bo Xiao, Fang-fang Bi, Xiao-Qin Lu, Xiao-Mei W. Protective effects of quercetin against status epilepticus induced hippocampal neuronal injury in rats: involvement of X-linked inhibitor of apoptosis protein. Acta neurologica Belgica. vol 111. issue 3. 2012-01-04. PMID:22141284. |
together, the study suggests neuroprotective effects of quercetin on hippocampal injury post status epilepticus and the effects may be associated with regulation of the x-linked inhibitor of apoptosis protein and the caspase-3 protein, which can be a decisive factor for apoptosis and survival of neurons in hippocampus. |
2012-01-04 |
2023-08-12 |
rat |
| Lin Ye, Feng Wang, Rui-Hua Yan. Diabetes impairs learning performance and affects the mitochondrial function of hippocampal pyramidal neurons. Brain research. vol 1411. 2011-12-21. PMID:21798520. |
release of cyt-c from mitochondria into cytoplasm may play a role in apoptosis of the ca1 pyramidal neurons, which resulted in a decrease of the number of neurons in hippocampus and impaired the performance function. |
2011-12-21 |
2023-08-12 |
rat |