| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jingquan Gao, Hongmei Wu, Yonggang Cao, Shuang Liang, Caihong Sun, Peng Wang, Ji Wang, Hongli Sun, Lijie W. Maternal DHA supplementation protects rat offspring against impairment of learning and memory following prenatal exposure to valproic acid. The Journal of nutritional biochemistry. vol 35. 2017-10-23. PMID:27469996. |
these findings suggest that maternal feeding with dha may prevent prenatal vpa-induced impairment of learning and memory, normalize several different molecules associated with oxidative stress and apoptosis in the hippocampus of offspring, and exert preventive effects on prenatal vpa-induced brain dysfunction. |
2017-10-23 |
2023-08-13 |
rat |
| Hong-Feng Gu, Hai-Zhe Li, Xue-Jiao Xie, Ya-Ling Tang, Xiao-Qing Tang, Ya-Xiong Nie, Duan-Fang Lia. Oxidized low-density lipoprotein induced mouse hippocampal HT-22 cell damage via promoting the shift from autophagy to apoptosis. CNS neuroscience & therapeutics. vol 23. issue 4. 2017-10-18. PMID:28233453. |
oxidized low-density lipoprotein induced mouse hippocampal ht-22 cell damage via promoting the shift from autophagy to apoptosis. |
2017-10-18 |
2023-08-13 |
mouse |
| Fanny Pineau, Geoffrey Canet, Catherine Desrumaux, Hazel Hunt, Nathalie Chevallier, Matthias Ollivier, Joseph K Belanoff, Laurent Givaloi. New selective glucocorticoid receptor modulators reverse amyloid-β peptide-induced hippocampus toxicity. Neurobiology of aging. vol 45. 2017-10-17. PMID:27459932. |
we confirm the expected properties of the nonselective gr antagonist (mifepristone) because in addition to restoring basal circulating glucocorticoids levels, mifepristone totally reverses synaptic deficits and hippocampal apoptosis processes. |
2017-10-17 |
2023-08-13 |
Not clear |
| Dragana Filipović, Nevena Todorović, Rick E Bernardi, Peter Gas. Oxidative and nitrosative stress pathways in the brain of socially isolated adult male rats demonstrating depressive- and anxiety-like symptoms. Brain structure & function. vol 222. issue 1. 2017-10-16. PMID:27033097. |
this review also highlights the differential susceptibility of prefrontal cortex and hippocampus to oxidative stress following csis and suggests a possible cellular pathway of stress tolerance that preserves the hippocampus from molecular damage and apoptosis. |
2017-10-16 |
2023-08-13 |
rat |
| Ehsan Pourmemar, Alireza Majdi, Morteza Haramshahi, Mahnaz Talebi, Pouran Karimi, Saeed Sadigh-Etegha. Intranasal Cerebrolysin Attenuates Learning and Memory Impairments in D-galactose-Induced Senescence in Mice. Experimental gerontology. vol 87. issue Pt A. 2017-10-16. PMID:27894939. |
apoptosis rate in the hippocampus was evaluated by tunel staining of brain tissue. |
2017-10-16 |
2023-08-13 |
mouse |
| Samira Hajheidari, Hamid Reza Sameni, Ahmad Reza Bandegi, Hossein Miladi-Gorj. Effects of prolonged abstinence from METH on the hippocampal BDNF levels, neuronal numbers and apoptosis in methamphetamine-sensitized rats. Neuroscience letters. vol 645. 2017-10-10. PMID:28249787. |
effects of prolonged abstinence from meth on the hippocampal bdnf levels, neuronal numbers and apoptosis in methamphetamine-sensitized rats. |
2017-10-10 |
2023-08-13 |
rat |
| Samira Hajheidari, Hamid Reza Sameni, Ahmad Reza Bandegi, Hossein Miladi-Gorj. Effects of prolonged abstinence from METH on the hippocampal BDNF levels, neuronal numbers and apoptosis in methamphetamine-sensitized rats. Neuroscience letters. vol 645. 2017-10-10. PMID:28249787. |
this study evaluated serum and hippocampal bdnf levels, neuronal numbers and apoptosis in meth-sensitized and abstinent rats. |
2017-10-10 |
2023-08-13 |
rat |
| Xian T Lu, Yun Ma, Hang J Zhang, Mei Q Jin, Jun H Tan. Enantioselective apoptosis and oxidative damage induced by individual isomers of profenofos in primary hippocampal neurons. Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes. vol 52. issue 7. 2017-10-10. PMID:28541776. |
enantioselective apoptosis and oxidative damage induced by individual isomers of profenofos in primary hippocampal neurons. |
2017-10-10 |
2023-08-13 |
Not clear |
| Na Jin, Huazhang Zhu, Xiao Liang, Wei Huang, Qingguo Xie, Peng Xiao, Jiazuan Ni, Qiong Li. Sodium selenate activated Wnt/β-catenin signaling and repressed amyloid-β formation in a triple transgenic mouse model of Alzheimer's disease. Experimental neurology. vol 297. 2017-10-05. PMID:28711506. |
increased aβ generation, tau hyperphosphorylation and neuronal apoptosis were found in the hippocampus of ad model mouse. |
2017-10-05 |
2023-08-13 |
mouse |
| Shuli Liang, Limin Zhang, Xiaoman Yu, Shaohui Zhang, Guojun Zhang, Ping Din. Neuroprotective Effect of Electric Conduction Treatment on Hippocampus Cell Apoptosis in KA Induced Acute Temporal Lobe Epileptic Rats. Brain stimulation. vol 9. issue 6. 2017-10-04. PMID:27553886. |
neuroprotective effect of electric conduction treatment on hippocampus cell apoptosis in ka induced acute temporal lobe epileptic rats. |
2017-10-04 |
2023-08-13 |
rat |
| Mei Qiu, Yang-Ping Shentu, Ji Zeng, Xiao-Chuan Wang, Xiong Yan, Xin-Wen Zhou, Xiao-Peng Jing, Qun Wang, Heng-Ye Man, Jian-Zhi Wang, Rong Li. Zinc mediates the neuronal activity-dependent anti-apoptotic effect. PloS one. vol 12. issue 8. 2017-10-04. PMID:28787459. |
using cultured hippocampal slices and primary neurons we show that a typical apoptosis inducer-staurosporine (stp) was able to cause concentration-dependent apoptotic cell death in brain slices; enhanced synaptic activity by bicuculline (bic)/4-aminopyridine (ap) treatment effectively prevented neurons from stp-induced cell apoptosis, as indicated by increased cell survival and suppressed caspase-3 activity. |
2017-10-04 |
2023-08-13 |
Not clear |
| Majid Motaghinejad, Manijeh Motevalian, Mohammad Abdollahi, Mansour Heidari, Zahra Madj. Topiramate Confers Neuroprotection Against Methylphenidate-Induced Neurodegeneration in Dentate Gyrus and CA1 Regions of Hippocampus via CREB/BDNF Pathway in Rats. Neurotoxicity research. vol 31. issue 3. 2017-10-02. PMID:28078543. |
the current study evaluates in vivo role of creb/bdnf in tpm protection of the rat hippocampal cells from methylphenidate-induced apoptosis, oxidative stress, and inflammation. |
2017-10-02 |
2023-08-13 |
rat |
| Junhong Guan, Xiangtai Wei, Shengtao Qu, Tao Lv, Qiang Fu, Ye Yua. Osthole prevents cerebral ischemia-reperfusion injury via the Notch signaling pathway. Biochemistry and cell biology = Biochimie et biologie cellulaire. vol 95. issue 4. 2017-10-02. PMID:28257582. |
in this study, we established a rat model of middle cerebral artery occlusion/reperfusion (mcao/r) in vivo and found that mcao/r caused cerebral infarction, hippocampus neuronal injury and apoptosis, and also activated the notch 1 signaling pathway. |
2017-10-02 |
2023-08-13 |
rat |
| Junhong Guan, Xiangtai Wei, Shengtao Qu, Tao Lv, Qiang Fu, Ye Yua. Osthole prevents cerebral ischemia-reperfusion injury via the Notch signaling pathway. Biochemistry and cell biology = Biochimie et biologie cellulaire. vol 95. issue 4. 2017-10-02. PMID:28257582. |
however, treatment with osthole further enhanced the activity of notch 1 signaling and reduced the cerebral infarction as well as the hippocampus neuronal injury and apoptosis induced by mcao/r in a dose-dependent manner. |
2017-10-02 |
2023-08-13 |
rat |
| Nasra Naeim Ayuo. Evaluation of the antidepressant-like effect of musk in an animal model of depression: how it works. Anatomical science international. vol 92. issue 4. 2017-09-28. PMID:27444866. |
it reduced the hippocampal neuronal apoptosis and stimulated neurogenesis in the dentate gyrus. |
2017-09-28 |
2023-08-13 |
mouse |
| Piangkwan Sa-Nguanmoo, Pongpan Tanajak, Sasiwan Kerdphoo, Pattarapong Satjaritanun, Xiaojie Wang, Guang Liang, Xiaokun Li, Chao Jiang, Wasana Pratchayasakul, Nipon Chattipakorn, Siriporn C Chattipakor. FGF21 improves cognition by restored synaptic plasticity, dendritic spine density, brain mitochondrial function and cell apoptosis in obese-insulin resistant male rats. Hormones and behavior. vol 85. 2017-09-26. PMID:27566237. |
we hypothesized that fgf21 prevented cognitive decline in obese-insulin resistant rats by improving hippocampal synaptic plasticity, dendritic spine density, brain mitochondrial function and brain fgf21 signaling as well as decreasing brain cell apoptosis. |
2017-09-26 |
2023-08-13 |
human |
| Piangkwan Sa-Nguanmoo, Pongpan Tanajak, Sasiwan Kerdphoo, Pattarapong Satjaritanun, Xiaojie Wang, Guang Liang, Xiaokun Li, Chao Jiang, Wasana Pratchayasakul, Nipon Chattipakorn, Siriporn C Chattipakor. FGF21 improves cognition by restored synaptic plasticity, dendritic spine density, brain mitochondrial function and cell apoptosis in obese-insulin resistant male rats. Hormones and behavior. vol 85. 2017-09-26. PMID:27566237. |
at the end of the treatment, cognitive function, metabolic parameters, pro-inflammatory markers, brain mitochondrial function, cell apoptosis, hippocampal synaptic plasticity, dendritic spine density and brain fgf21 signaling were determined. |
2017-09-26 |
2023-08-13 |
human |
| Piangkwan Sa-Nguanmoo, Pongpan Tanajak, Sasiwan Kerdphoo, Pattarapong Satjaritanun, Xiaojie Wang, Guang Liang, Xiaokun Li, Chao Jiang, Wasana Pratchayasakul, Nipon Chattipakorn, Siriporn C Chattipakor. FGF21 improves cognition by restored synaptic plasticity, dendritic spine density, brain mitochondrial function and cell apoptosis in obese-insulin resistant male rats. Hormones and behavior. vol 85. 2017-09-26. PMID:27566237. |
the results showed that vehicle-treated hfd-fed rats developed obese-insulin resistance and cognitive decline with impaired hippocampal synaptic plasticity, decreased dendritic spine density, brain mitochondrial dysfunction and increased brain cell apoptosis. |
2017-09-26 |
2023-08-13 |
human |
| Piangkwan Sa-Nguanmoo, Pongpan Tanajak, Sasiwan Kerdphoo, Pattarapong Satjaritanun, Xiaojie Wang, Guang Liang, Xiaokun Li, Chao Jiang, Wasana Pratchayasakul, Nipon Chattipakorn, Siriporn C Chattipakor. FGF21 improves cognition by restored synaptic plasticity, dendritic spine density, brain mitochondrial function and cell apoptosis in obese-insulin resistant male rats. Hormones and behavior. vol 85. 2017-09-26. PMID:27566237. |
fgf21-treated obese-insulin resistant rats had improved peripheral insulin sensitivity, increased hippocampal synaptic plasticity, increased dendritic spine density, restored brain mitochondrial function, attenuated brain cells apoptosis and increased brain fgf21 signaling, leading to a prevention of cognitive decline. |
2017-09-26 |
2023-08-13 |
human |
| Maria Camargo Moreno, Sandra M Mooney, Frank A Middleto. Heterogeneity of p53 dependent genomic responses following ethanol exposure in a developmental mouse model of fetal alcohol spectrum disorder. PloS one. vol 12. issue 7. 2017-09-26. PMID:28723918. |
we quantified apoptosis by active caspase-3 immunohistochemistry and apoptag™ labeling, then determined total rna expression levels in laminae of si and hippocampal subregions. |
2017-09-26 |
2023-08-13 |
mouse |