| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ershun Liang, Min Ma, Lei Wang, Xue Liu, Jinfeng Xu, Mingxiang Zhang, Ruixue Yang, Yuxia Zha. The BET/BRD inhibitor JQ1 attenuates diabetes-induced cognitive impairment in rats by targeting Nox4-Nrf2 redox imbalance. Biochemical and biophysical research communications. vol 495. issue 1. 2018-01-05. PMID:29113796. |
significant improvement of cognitive performance was observed after treatment with the bet/brd inhibitor jq1, accompanied by decreased oxidative stress, neuroinflammation and apoptosis in the hippocampus. |
2018-01-05 |
2023-08-13 |
rat |
| Yu-Xiang Wang, Feng Zhang, Xue-Ling Ma, Cong-Cong He, Kun Tian, Hong-Gang Wang, Di An, Bin Heng, Lai-Hua Xie, Yan-Qiang Li. Oxygen-glucose deprivation enhancement of cell death/apoptosis in PC12 cells and hippocampal neurons correlates with changes in neuronal excitatory amino acid neurotransmitter signaling and potassium currents. Neuroreport. vol 27. issue 8. 2018-01-04. PMID:27082843. |
our experimental results showed that ogd significantly decreased cell viability and markedly enhanced apoptosis in pc12 cells and hippocampal neurons. |
2018-01-04 |
2023-08-13 |
Not clear |
| Wanting Dong, Dan Xu, Zewen Hu, Xia He, Zijing Guo, Zhexiao Jiao, Ying Yu, Hui Wan. Low-functional programming of the CREB/BDNF/TrkB pathway mediates cognitive impairment in male offspring after prenatal dexamethasone exposure. Toxicology letters. vol 283. 2018-01-04. PMID:29111458. |
the adult pde male offspring rats exhibited cognitive impairment, decreased cell proliferation and increased cell apoptosis in the hippocampus, along with damaged synaptic plasticity and disrupted protein synthesis. |
2018-01-04 |
2023-08-13 |
rat |
| Yubin Liang, Min Huang, Xin Jiang, Qiong Liu, Xin Chang, Yi Gu. The neuroprotective effects of Berberine against amyloid β-protein-induced apoptosis in primary cultured hippocampal neurons via mitochondria-related caspase pathway. Neuroscience letters. vol 655. 2018-01-01. PMID:28668383. |
the neuroprotective effects of berberine against amyloid β-protein-induced apoptosis in primary cultured hippocampal neurons via mitochondria-related caspase pathway. |
2018-01-01 |
2023-08-13 |
Not clear |
| Ming-Hsiu Wu, Chung-Ching Chio, Kuen-Jer Tsai, Ching-Ping Chang, Nan-Kai Lin, Chao-Ching Huang, Mao-Tsun Li. Obesity Exacerbates Rat Cerebral Ischemic Injury through Enhancing Ischemic Adiponectin-Containing Neuronal Apoptosis. Molecular neurobiology. vol 53. issue 6. 2017-12-29. PMID:26126515. |
compared with cd rats, wd rats exhibited higher levels of brain infarct, neurologic deficits, brain edema, and apoptosis of apn-containing neurons; upregulation of both adr-1 and p38 mitogen-activated protein kinase (p38mapk); and downregulation of adr-2 in ischemic brain tissues including frontal cortex, striatum, and hippocampus. |
2017-12-29 |
2023-08-13 |
rat |
| Ukpong B Eyo, Samuel A Miner, Joshua A Weiner, Michael E Daile. Developmental changes in microglial mobilization are independent of apoptosis in the neonatal mouse hippocampus. Brain, behavior, and immunity. vol 55. 2017-12-29. PMID:26576723. |
developmental changes in microglial mobilization are independent of apoptosis in the neonatal mouse hippocampus. |
2017-12-29 |
2023-08-13 |
mouse |
| Ukpong B Eyo, Samuel A Miner, Joshua A Weiner, Michael E Daile. Developmental changes in microglial mobilization are independent of apoptosis in the neonatal mouse hippocampus. Brain, behavior, and immunity. vol 55. 2017-12-29. PMID:26576723. |
here, we assessed the extent to which microglial cell density, morphology, motility, and migration are regulated by developmental apoptosis, focusing on the first postnatal week in the mouse hippocampus when the density of apoptotic bodies peaks at postnatal day 4 and declines sharply thereafter. |
2017-12-29 |
2023-08-13 |
mouse |
| Yang Yu, Xiuquan Wu, Jingnan Pu, Peng Luo, Wenke Ma, Jiu Wang, Jialiang Wei, Yuanxin Wang, Zhou Fe. Lycium barbarum polysaccharide protects against oxygen glucose deprivation/reoxygenation-induced apoptosis and autophagic cell death via the PI3K/Akt/mTOR signaling pathway in primary cultured hippocampal neurons. Biochemical and biophysical research communications. vol 495. issue 1. 2017-12-28. PMID:29183728. |
lycium barbarum polysaccharide protects against oxygen glucose deprivation/reoxygenation-induced apoptosis and autophagic cell death via the pi3k/akt/mtor signaling pathway in primary cultured hippocampal neurons. |
2017-12-28 |
2023-08-13 |
Not clear |
| Bing Zhang, Jia-Wei Zhang, Wei-Ping Wang, Rui-Fang Dong, Shuang Tian, Chao Zhan. Effect of lamotrigine on epilepsy-induced cognitive impairment and hippocampal neuronal apoptosis in pentylenetetrazole-kindled animal model. Synapse (New York, N.Y.). vol 71. issue 2. 2017-12-22. PMID:27733018. |
effect of lamotrigine on epilepsy-induced cognitive impairment and hippocampal neuronal apoptosis in pentylenetetrazole-kindled animal model. |
2017-12-22 |
2023-08-13 |
Not clear |
| Chong Chen, Tie-Zhu Ma, Li-Na Wang, Jing-Jing Wang, Yue Tu, Ming-Liang Zhao, Sai Zhang, Hong-Tao Sun, Xiao-Hong L. Mild hypothermia facilitates the long-term survival of newborn cells in the dentate gyrus after traumatic brain injury by diminishing a pro-apoptotic microenvironment. Neuroscience. vol 335. 2017-12-21. PMID:27583772. |
although previous research has demonstrated that traumatic brain injury (tbi) accelerates the proliferation of neural stem cells in dentate gyrus of the hippocampus, most of these newborn cells undergo apoptosis in a traumatic microenvironment. |
2017-12-21 |
2023-08-13 |
rat |
| Yicong Chen, Leo Veenman, Sukhdev Singh, Fubing Ouyang, Jiahui Liang, Weixian Huang, Ilan Marek, Jinsheng Zeng, Moshe Gavis. 2-Cl-MGV-1 Ameliorates Apoptosis in the Thalamus and Hippocampus and Cognitive Deficits After Cortical Infarct in Rats. Stroke. vol 48. issue 12. 2017-12-19. PMID:29146879. |
2-cl-mgv-1 ameliorates apoptosis in the thalamus and hippocampus and cognitive deficits after cortical infarct in rats. |
2017-12-19 |
2023-08-13 |
rat |
| Yicong Chen, Leo Veenman, Sukhdev Singh, Fubing Ouyang, Jiahui Liang, Weixian Huang, Ilan Marek, Jinsheng Zeng, Moshe Gavis. 2-Cl-MGV-1 Ameliorates Apoptosis in the Thalamus and Hippocampus and Cognitive Deficits After Cortical Infarct in Rats. Stroke. vol 48. issue 12. 2017-12-19. PMID:29146879. |
focal cortical infarction causes neuronal apoptosis in the ipsilateral nonischemic thalamus and hippocampus, which is potentially associated with poststroke cognitive deficits. |
2017-12-19 |
2023-08-13 |
rat |
| Yicong Chen, Leo Veenman, Sukhdev Singh, Fubing Ouyang, Jiahui Liang, Weixian Huang, Ilan Marek, Jinsheng Zeng, Moshe Gavis. 2-Cl-MGV-1 Ameliorates Apoptosis in the Thalamus and Hippocampus and Cognitive Deficits After Cortical Infarct in Rats. Stroke. vol 48. issue 12. 2017-12-19. PMID:29146879. |
we examined the effects of the novel tspo ligand 2-(2-chlorophenyl) quinazolin-4-yl dimethylcarbamate (2-cl-mgv-1) on poststroke cognitive deficits, neuronal mitochondrial apoptosis, and secondary damage in the ipsilateral thalamus and hippocampus after cortical infarction. |
2017-12-19 |
2023-08-13 |
rat |
| Bhupesh Patel, Saroj Kumar Das, Manorama Patr. Neonatal Benzo[a]pyrene Exposure Induces Oxidative Stress and DNA Damage Causing Neurobehavioural Changes during the Early Adolescence Period in Rats. Developmental neuroscience. vol 38. issue 2. 2017-12-14. PMID:27271523. |
b[a]p significantly increased anxiolytic-like behaviour and oxidative dna damage in the hippocampus causing apoptosis that may lead to neurodegeneration in adolescence. |
2017-12-14 |
2023-08-13 |
rat |
| Li Xue, Wen-Lan Wang, Ya Li, Xu Gong, Jun-Xiang Bao, Hai-Jun Zhang, Xiao-Ping Xie, Yao-Ming Chang, Jin-Sheng L. Effects of hyperbaric oxygen on hippocampal neuronal apoptosis in rats with acute carbon monoxide poisoning. Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc. vol 44. issue 2. 2017-12-12. PMID:28777902. |
effects of hyperbaric oxygen on hippocampal neuronal apoptosis in rats with acute carbon monoxide poisoning. |
2017-12-12 |
2023-08-13 |
rat |
| Li Xue, Wen-Lan Wang, Ya Li, Xu Gong, Jun-Xiang Bao, Hai-Jun Zhang, Xiao-Ping Xie, Yao-Ming Chang, Jin-Sheng L. Effects of hyperbaric oxygen on hippocampal neuronal apoptosis in rats with acute carbon monoxide poisoning. Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc. vol 44. issue 2. 2017-12-12. PMID:28777902. |
this study aimed to investigate neuronal apoptosis and the effects of hyperbaric oxygen (hbo₂) on different regions of the rat hippocampus after co poisoning. |
2017-12-12 |
2023-08-13 |
rat |
| Yang Yu, Linjing Feng, Junnan Li, Xiaoxin Lan, Lixiang A, Xiaoyan Lv, Ming Zhang, Li Che. The alteration of autophagy and apoptosis in the hippocampus of rats with natural aging-dependent cognitive deficits. Behavioural brain research. vol 334. 2017-12-11. PMID:28688896. |
the alteration of autophagy and apoptosis in the hippocampus of rats with natural aging-dependent cognitive deficits. |
2017-12-11 |
2023-08-13 |
rat |
| Yang Yu, Linjing Feng, Junnan Li, Xiaoxin Lan, Lixiang A, Xiaoyan Lv, Ming Zhang, Li Che. The alteration of autophagy and apoptosis in the hippocampus of rats with natural aging-dependent cognitive deficits. Behavioural brain research. vol 334. 2017-12-11. PMID:28688896. |
the present study was aim to explore aging-dependent changes in hippocampal autophagy and apoptosis in a natural aging rat model from adult to old stages and to discover a suitable age for treating neurodegenerative diseases. |
2017-12-11 |
2023-08-13 |
rat |
| Zhang Qi, Yuan Tianbao, Li Yanan, Xin Xi, He Jinhua, Wang Qiuju. Pre-treatment with nimodipine and 7.5% hypertonic saline protects aged rats against postoperative cognitive dysfunction via inhibiting hippocampal neuronal apoptosis. Behavioural brain research. vol 321. 2017-11-29. PMID:28017853. |
pre-treatment with nimodipine and 7.5% hypertonic saline protects aged rats against postoperative cognitive dysfunction via inhibiting hippocampal neuronal apoptosis. |
2017-11-29 |
2023-08-13 |
rat |
| Mengmei Yin, Yali Chen, Hui Zheng, Tinglin Pu, Charles Marshall, Ting Wu, Ming Xia. Assessment of mouse cognitive and anxiety-like behaviors and hippocampal inflammation following a repeated and intermittent paradoxical sleep deprivation procedure. Behavioural brain research. vol 321. 2017-11-29. PMID:28043900. |
moreover, neuroinflammation, microglial activation and neuronal apoptosis were observed in the hippocampus of model mice even recovery for 3 weeks later. |
2017-11-29 |
2023-08-13 |
mouse |