| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Qiliang Li, Wenqi Song, Ze Tian, Peichang Wan. Aminoguanidine alleviated MMA-induced impairment of cognitive ability in rats by downregulating oxidative stress and inflammatory reaction. Neurotoxicology. vol 59. 2017-11-22. PMID:28223158. |
the ag-treated rats had a decreased level of apoptosis of the hippocampal neurons, which could be the structural basis of the observed neural behavior protection. |
2017-11-22 |
2023-08-13 |
rat |
| Giuseppe Musumeci, Paola Castrogiovanni, Marta Anna Szychlinska, Rosa Imbesi, Carla Loreto, Sergio Castorina, Salvatore Giunt. Protective effects of high Tryptophan diet on aging-induced passive avoidance impairment and hippocampal apoptosis. Brain research bulletin. vol 128. 2017-11-21. PMID:27889579. |
protective effects of high tryptophan diet on aging-induced passive avoidance impairment and hippocampal apoptosis. |
2017-11-21 |
2023-08-13 |
rat |
| Giuseppe Musumeci, Paola Castrogiovanni, Marta Anna Szychlinska, Rosa Imbesi, Carla Loreto, Sergio Castorina, Salvatore Giunt. Protective effects of high Tryptophan diet on aging-induced passive avoidance impairment and hippocampal apoptosis. Brain research bulletin. vol 128. 2017-11-21. PMID:27889579. |
altogether, our data suggest that enhanced trp intake, and in consequence a potential increase in 5-ht neurotransmission, might be beneficial in preventing age-related detrimental features by inhibition of hippocampal apoptosis. |
2017-11-21 |
2023-08-13 |
rat |
| Huaihai Lu, Kun Ma, Liwei Jin, He Zhu, Ruiqi Ca. 17β-estradiol rescues damages following traumatic brain injury from molecule to behavior in mice. Journal of cellular physiology. vol 233. issue 2. 2017-11-21. PMID:28681915. |
apoptosis in the hippocampus was assayed with fluoro-jade b staining and tunel staining. |
2017-11-21 |
2023-08-13 |
mouse |
| Huaihai Lu, Kun Ma, Liwei Jin, He Zhu, Ruiqi Ca. 17β-estradiol rescues damages following traumatic brain injury from molecule to behavior in mice. Journal of cellular physiology. vol 233. issue 2. 2017-11-21. PMID:28681915. |
additionally, e2 improved many aspects of deleterious effects of tbi on the hippocampus, including neuronal apoptosis, dysfunction in spatial memory, reduction in nr2b, enhancement of oxidative stress, and activation of erk1/2 pathway. |
2017-11-21 |
2023-08-13 |
mouse |
| Yueqi Zhang, Qiliang Li, Chengeng Liu, Shichao Gao, Hong Ping, Jinling Wang, Peichang Wan. MiR-214-3p attenuates cognition defects via the inhibition of autophagy in SAMP8 mouse model of sporadic Alzheimer's disease. Neurotoxicology. vol 56. 2017-11-20. PMID:27397902. |
taken together, these results suggest that mir-214-3p suppresses autophagy and alleviates hippocampal neuron apoptosis, which indicates that mir-214-3p represents a new potential neuroprotective factor for sad. |
2017-11-20 |
2023-08-13 |
mouse |
| Jennifer L Walters, John J Chelonis, Charles M Fogle, Beverley A Orser, Merle G Paul. Single and repeated exposures to the volatile anesthetic isoflurane do not impair operant performance in aged rats. Neurotoxicology. vol 56. 2017-11-20. PMID:27498192. |
volatile anesthetics have been shown to increase cellular inflammation and apoptosis within the hippocampus of aged rodents, while producing corresponding impairments in hippocampal-dependent brain functions. |
2017-11-20 |
2023-08-13 |
rat |
| Blair C Weig, Jason R Richardson, Herbert E Lowndes, Kenneth R Reuh. Trimethyltin intoxication induces the migration of ventricular/subventricular zone cells to the injured murine hippocampus. Neurotoxicology. vol 54. 2017-11-17. PMID:27045884. |
sublethal exposure to the neurotoxicant trimethyltin (tmt) causes dose-dependent necrosis and apoptosis in the hippocampus dentate gyrus and increases sgz stem cell proliferation to generate new granule cells. |
2017-11-17 |
2023-08-13 |
mouse |
| Yang Yang, Xi Li, Qinwei Sun, Bin He, Yimin Jia, Demin Cai, Ruqian Zha. Folate deprivation induces cell cycle arrest at G0/G1 phase and apoptosis in hippocampal neuron cells through down-regulation of IGF-1 signaling pathway. The international journal of biochemistry & cell biology. vol 79. 2017-11-17. PMID:27592453. |
folate deprivation induces cell cycle arrest at g0/g1 phase and apoptosis in hippocampal neuron cells through down-regulation of igf-1 signaling pathway. |
2017-11-17 |
2023-08-13 |
Not clear |
| Yang Yang, Xi Li, Qinwei Sun, Bin He, Yimin Jia, Demin Cai, Ruqian Zha. Folate deprivation induces cell cycle arrest at G0/G1 phase and apoptosis in hippocampal neuron cells through down-regulation of IGF-1 signaling pathway. The international journal of biochemistry & cell biology. vol 79. 2017-11-17. PMID:27592453. |
here we use ht-22 hippocampal neuron cells as model to investigate the effect of folate deprivation (fd) on cell proliferation and apoptosis, and to elucidate the underlying mechanism. |
2017-11-17 |
2023-08-13 |
Not clear |
| Yang Yang, Xi Li, Qinwei Sun, Bin He, Yimin Jia, Demin Cai, Ruqian Zha. Folate deprivation induces cell cycle arrest at G0/G1 phase and apoptosis in hippocampal neuron cells through down-regulation of IGF-1 signaling pathway. The international journal of biochemistry & cell biology. vol 79. 2017-11-17. PMID:27592453. |
taken together, down-regulation of igf-1 expression and signaling is involved in fd-induced cell cycle arrest and apoptosis in ht-22 hippocampal neuron cells, which is associated with an abnormal activation of methyl transfer pathway and hypermethylation of igf-1 gene promoter. |
2017-11-17 |
2023-08-13 |
Not clear |
| S Yu, I Zutshi, R Stoffel, J Zhang, A P Ventura-Silva, N Sousa, P S Costa, F Holsboer, A Patchev, O F X Almeid. Antidepressant responsiveness in adulthood is permanently impaired after neonatal destruction of the neurogenic pool. Translational psychiatry. vol 7. issue 1. 2017-11-16. PMID:28045461. |
interestingly, although nd depletes the neurogenic pool, it does not permanently abolish the proliferative machinery of the residual npc population; however, nd increases the susceptibility of hippocampal granule neurons to apoptosis. |
2017-11-16 |
2023-08-13 |
rat |
| S Yuliani, S Widyarini, Mustofa, G Partadiredj. Turmeric extract inhibits apoptosis of hippocampal neurons of trimethyltin-exposed rats. Bratislavske lekarske listy. vol 118. issue 3. 2017-11-16. PMID:28319408. |
turmeric extract inhibits apoptosis of hippocampal neurons of trimethyltin-exposed rats. |
2017-11-16 |
2023-08-13 |
rat |
| Tae-Woon Kim, Yun-Hee Sun. Regular exercise promotes memory function and enhances hippocampal neuroplasticity in experimental autoimmune encephalomyelitis mice. Neuroscience. vol 346. 2017-11-09. PMID:28108255. |
we found decreased memory ability in eae mice, accompanied by impaired myelination, increased apoptosis and cell proliferation, and decreased bdnf in the hippocampus. |
2017-11-09 |
2023-08-13 |
mouse |
| Hang Cao, Rosi Bissinger, Anja T Umbach, Meinrad Gawaz, Florian Lan. Temsirolimus Sensitive Stimulation of Platelet Activity, Apoptosis and Aggregation by Collagen Related Peptide. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. vol 42. issue 3. 2017-11-07. PMID:28693022. |
on the other hand, temsirolimus has been shown to protect against apoptosis of hippocampal neurons. |
2017-11-07 |
2023-08-13 |
Not clear |
| K E Boschen, A Y Klintsov. Neurotrophins in the Brain: Interaction With Alcohol Exposure During Development. Vitamins and hormones. vol 104. 2017-11-02. PMID:28215296. |
these areas of overlap include formation of long-term potentiation, oxidative stress processes, neuroinflammation, apoptosis and cell loss, hippocampal adult neurogenesis, dendritic morphology and spine density, vasculogenesis and angiogenesis, and behaviors related to spatial memory, anxiety, and depression. |
2017-11-02 |
2023-08-13 |
Not clear |
| Xiang Lv, Jia Yan, Jue Jiang, Xuhui Zhou, Yi Lu, Hong Jian. MicroRNA-27a-3p suppression of peroxisome proliferator-activated receptor-γ contributes to cognitive impairments resulting from sevoflurane treatment. Journal of neurochemistry. vol 143. issue 3. 2017-11-02. PMID:28881034. |
down-regulation of mir-27a-3p expression decreased sevoflurane-induced hippocampal neuron apoptosis by decreasing inflammation and oxidative stress-related protein expression through the up-regulation of ppar-γ. |
2017-11-02 |
2023-08-13 |
mouse |
| Deyan Kong, Qian Liu, Guangxu Xu, Zhenhua Huang, Ning Luo, Yuanheng Huang, Keshu Ca. Synergistic effect of tanshinone IIA and mesenchymal stem cells on preventing learning and memory deficits via anti-apoptosis, attenuating tau phosphorylation and enhancing the activity of central cholinergic system in vascular dementia. Neuroscience letters. vol 637. 2017-10-31. PMID:27845241. |
the combined administration of tsa and mscs demonstrated a synergistic effect on suppressing neuronal apoptosis in the hippocampus, attenuating tau phosphorylation and enhancing the activity of central cholinergic system. |
2017-10-31 |
2023-08-13 |
rat |
| Sehee Kim, Chanyang Kim, Seungjoon Par. Ghrelin gene products rescue cultured adult rat hippocampal neural stem cells from high glucose insult. Journal of molecular endocrinology. vol 57. issue 3. 2017-10-26. PMID:27530317. |
treatment of hippocampal nscs with ag, uag or ob inhibited hg-induced cell death and apoptosis. |
2017-10-26 |
2023-08-13 |
rat |
| Jingquan Gao, Hongmei Wu, Yonggang Cao, Shuang Liang, Caihong Sun, Peng Wang, Ji Wang, Hongli Sun, Lijie W. Maternal DHA supplementation protects rat offspring against impairment of learning and memory following prenatal exposure to valproic acid. The Journal of nutritional biochemistry. vol 35. 2017-10-23. PMID:27469996. |
the results showed that maternal feeding of dha to the prenatal exposed to vpa (1) prevented vpa-induced learning and memory impairment but did not change social-related behavior, (2) increased total dha content in offspring plasma and hippocampus, (3) rescued vpa-induced neuronal loss and apoptosis of pyramidal cells in hippocampal ca1, (4) influenced the content of malondialdehyde and glutathione and the activities of superoxide dismutase and glutathione in the hippocampus, (5) altered levels of apoptosis-related proteins (bcl-2, bax and caspase-3) and inhibited the activity of caspase-3 in offspring hippocampus and (6) enhanced relative levels of p-camkii and p-creb proteins in the hippocampus. |
2017-10-23 |
2023-08-13 |
rat |