| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kathrin Heiss, Luca Vanella, Paolo Murabito, Orazio Prezzavento, Agostino Marrazzo, Carlo Castruccio Castracani, Ignazio Barbagallo, Agata Zappalà, Emanuela Arena, Marinella Astuto, Antonino Giarratano, Giovanni Li Volt. Corrigendum to "(+)-Pentazocine reduces oxidative stress and apoptosis in microglia following hypoxia/reoxygenation injury" [Neurosci. Lett. 626 (2016) 142-148]. Neuroscience letters. vol 807. 2023-04-29. PMID:37119692. |
corrigendum to "(+)-pentazocine reduces oxidative stress and apoptosis in microglia following hypoxia/reoxygenation injury" [neurosci. |
2023-04-29 |
2023-08-14 |
Not clear |
| Jing Ren, Yuan Lv, Qiuyan Tian, Li Sun, Po Miao, Xiaofeng Yang, Li-Xiao Xu, Chen-Xi Feng, Mei Li, Qin Gu, Xing Feng, Xin Din. Suppression of Microglial ERO1a Alleviates Inflammation and Enhances the Efficacy of Rehabilitative Training After Ischemic Stroke. Molecular neurobiology. 2023-04-26. PMID:37100971. |
in contrast, suppression of microglial ero1a significantly reduced activation of both microglia and astrocyte, along with cell apoptosis. |
2023-04-26 |
2023-08-14 |
Not clear |
| Lei Xu, Xiaoxiong Zeng, Yanan Liu, Zufang Wu, Xiaojie Zheng, Xin Zhan. Effect of Dendrobium officinale polysaccharides on central nervous system disease: Based on gut microbiota. International journal of biological macromolecules. 2023-04-16. PMID:37062382. |
it can also inhibit the activation of astrocytes and microglia, further realizing the protective effect on neuronal apoptosis and apoptosis, thus exerting a significant alleviating effect on neurological diseases. |
2023-04-16 |
2023-08-14 |
human |
| Cheng-Long Zhu, Jian Xie, Qiang Liu, Yi Wang, Hui-Ru Li, Chang-Meng Yu, Peng Li, Xiao-Ming Deng, Jin-Jun Bian, Jia-Feng Wan. PD-L1 promotes GSDMD-mediated NET release by maintaining the transcriptional activity of Stat3 in sepsis-associated encephalopathy. International journal of biological sciences. vol 19. issue 5. 2023-04-14. PMID:37056920. |
here, we firstly show that in murine sepsis model, neutrophils and nets promote blood-brain barrier (bbb) disruption, neuronal apoptosis and microglia activation in hippocampus and induce hippocampus-dependent memory impairment. |
2023-04-14 |
2023-08-14 |
human |
| Su Jiang, Ying Xiong, Xinyan Wan. Engeletin ameliorates sevoflurane-induced cognitive impairment by activating PPAR-gamma in neonatal mice. Neuropathology : official journal of the Japanese Society of Neuropathology. 2023-04-10. PMID:37037475. |
the treatment of engeletin dramatically suppressed the activation of microglia and apoptosis induced by sev in the hippocampus of neonatal mice. |
2023-04-10 |
2023-08-14 |
mouse |
| Jian Liu, Jingyi Sun, Yanan Song, Mengyue Wang, Peng Zhao, Wendi Wang, Mingfeng Yang, Ying Wang, Yuqiang Song, Baoliang Su. Prussian Blue Nanozyme Treatment of Ischemic Brain Injury via Reducing Oxidative Stress Inhibits Inflammation, Suppresses Apoptosis, and Promotes Neurological Recovery. ACS chemical neuroscience. 2023-04-10. PMID:37038049. |
pbzyme inhibited the activation of macrophages and the release of inflammatory factors in the brain, promoted the polarization of microglia to m2, inhibited neuronal apoptosis, and promoted the recovery of neurological function after ischemic stroke. |
2023-04-10 |
2023-08-14 |
Not clear |
| Dongying Yan, Yuqing Yang, Jing Lang, Xiaobai Wang, Ying Huang, Jia Meng, Jie Wu, Xinning Zeng, Hong Li, Honglin Ma, Liang Ga. SIRT1/FOXO3-mediated autophagy signaling involved in manganese-induced neuroinflammation in microglia. Ecotoxicology and environmental safety. vol 256. 2023-04-07. PMID:37027942. |
the results of in vivo and in vitro experiments showed that overexposure to mn caused neuroinflammation impairment and autophagy dysfunction, accompanied by the increase of il-1β, il-6, and tnf-α mrna expression, and nerve cell apoptosis, microglia cell activation, nf-κb activation, poor neurobehavior performance. |
2023-04-07 |
2023-08-14 |
Not clear |
| Chia Bamshad, Mehryar Habibi Roudkenar, Mahmoud Abedinzade, Shahrokh Yousefzadeh Chabok, Zahra Pourmohammadi-Bejarpasi, Nima Najafi-Ghalehlou, Tomoaki Sato, Kazuo Tomita, Ali Jahanian-Najafabadi, Alireza Feizkhah, Amaneh Mohammadi Roushande. Human umbilical cord-derived mesenchymal stem cells-harvested mitochondrial transplantation improved motor function in TBI models through rescuing neuronal cells from apoptosis and alleviating astrogliosis and microglia activation. International immunopharmacology. vol 118. 2023-04-04. PMID:37015158. |
human umbilical cord-derived mesenchymal stem cells-harvested mitochondrial transplantation improved motor function in tbi models through rescuing neuronal cells from apoptosis and alleviating astrogliosis and microglia activation. |
2023-04-04 |
2023-08-14 |
human |
| Chia Bamshad, Mehryar Habibi Roudkenar, Mahmoud Abedinzade, Shahrokh Yousefzadeh Chabok, Zahra Pourmohammadi-Bejarpasi, Nima Najafi-Ghalehlou, Tomoaki Sato, Kazuo Tomita, Ali Jahanian-Najafabadi, Alireza Feizkhah, Amaneh Mohammadi Roushande. Human umbilical cord-derived mesenchymal stem cells-harvested mitochondrial transplantation improved motor function in TBI models through rescuing neuronal cells from apoptosis and alleviating astrogliosis and microglia activation. International immunopharmacology. vol 118. 2023-04-04. PMID:37015158. |
for this reason, in this study, we used this technique to transplant human umbilical cord-derived mesenchymal stem cells (huc-mscs)-derived mitochondria as a suitable source for mitochondrial isolation into rat models of tbi to examine its therapeutic benefit and the results showed that the successful mitochondrial internalisation in the neuronal cells significantly reduced the number of brain cells undergoing apoptosis, alleviated astrogliosis and microglia activation, retained normal brain morphology and cytoarchitecture, and improved sensorimotor functions in a rat model of tbi. |
2023-04-04 |
2023-08-14 |
human |
| Chia Bamshad, Mehryar Habibi Roudkenar, Mahmoud Abedinzade, Shahrokh Yousefzadeh Chabok, Zahra Pourmohammadi-Bejarpasi, Nima Najafi-Ghalehlou, Tomoaki Sato, Kazuo Tomita, Ali Jahanian-Najafabadi, Alireza Feizkhah, Amaneh Mohammadi Roushande. Human umbilical cord-derived mesenchymal stem cells-harvested mitochondrial transplantation improved motor function in TBI models through rescuing neuronal cells from apoptosis and alleviating astrogliosis and microglia activation. International immunopharmacology. vol 118. 2023-04-04. PMID:37015158. |
these data indicate that human umbilical cord-derived mesenchymal stem cells-isolated mitochondrial transplantation improves motor function in a rat model of tbi via rescuing neuronal cells from apoptosis and alleviating astrogliosis and microglia activation, maybe as a result of restoring the lost mitochondrial content. |
2023-04-04 |
2023-08-14 |
human |
| Wei Tang, Lu Liu, Yi Yan, Yongzhi Xi. Sodium houttuyfonate exerts its neuroprotection effect by inhibiting the M1 microglia polarization in a TLR4/NF-κB signal pathway. Brain research. 2023-04-03. PMID:37011720. |
in vitro, sh reduced tlr4/nf-κb expression in cultured primary microglia and decreased m1 microglial polarization and cell apoptosis in a lipopolysaccharide (lps)-pretreated microglia and neuron coculture system. |
2023-04-03 |
2023-08-14 |
rat |
| Anika Sood, Valencia Fernandes, Kumari Preeti, Dharmendra Kumar Khatri, Shashi Bala Sing. Sphingosine 1 phosphate lyase inhibition rescues cognition in diabetic mice by promoting anti-inflammatory microglia. Behavioural brain research. 2023-03-30. PMID:36997095. |
tigar, tp53-associated glycolysis and apoptosis regulator, is known to foster anti-inflammatory microglia and was found to be downregulated in the brain of type 2 diabetic mice. |
2023-03-30 |
2023-08-14 |
mouse |
| Yingwen Wang, Xiaomin Yang, Yunchuan Cao, Xiaoguo Li, Rui Xu, Jin Yan, Zongduo Guo, Shanquan Sun, Xiaochuan Sun, Yue W. Electroacupuncture alleviates early brain injury via modulating microglia polarization and suppressing neuroinflammation in a rat model of subarachnoid hemorrhage. Heliyon. vol 9. issue 3. 2023-03-27. PMID:36967957. |
data were gathered among sham group, sah-induced group, and ea-treated group of male sd rats, concerning mortality rates, weight loss, rotarod latencies, cerebral blood flow, cell apoptosis, pro-inflammatory cytokines releasing, apoptotic protein level, microglia activation and related signal pathway. |
2023-03-27 |
2023-08-14 |
rat |
| Yingwen Wang, Xiaomin Yang, Yunchuan Cao, Xiaoguo Li, Rui Xu, Jin Yan, Zongduo Guo, Shanquan Sun, Xiaochuan Sun, Yue W. Electroacupuncture alleviates early brain injury via modulating microglia polarization and suppressing neuroinflammation in a rat model of subarachnoid hemorrhage. Heliyon. vol 9. issue 3. 2023-03-27. PMID:36967957. |
these findings suggested that ea improved motor deficits and ameliorated early brain injury after sah probably via decreasing neuron apoptosis and anti-inflammation, which may involve modulation of microglia polarization. |
2023-03-27 |
2023-08-14 |
rat |
| Xiang-Ling Yuan, Shao-Lang Chen, Yanxuan Xu, Yao Yao, Jia-Jian Liang, Xi Zhuang, Eric S Hald, Tsz Kin N. Green tea extract enhances retinal ganglion cell survival and axonal regeneration in rats with optic nerve injury. The Journal of nutritional biochemistry. 2023-03-25. PMID:36965783. |
rna sequencing analysis identified the downregulation of inflammation, apoptosis, and microglia activation genes in the retina of rats with pre- or post-treatment with 275 mg/kg gte as compared to the saline-treated rats. |
2023-03-25 |
2023-08-14 |
rat |
| Vivekananda Budamagunta, Ashok Kumar, Asha Rani, Linda Bean, Sahana Manohar-Sindhu, Yang Yang, Daohong Zhou, Thomas C Foste. Effect of peripheral cellular senescence on brain aging and cognitive decline. Aging cell. 2023-03-24. PMID:36959691. |
relative to d + q, the abt-263 group exhibited increased expression of dg genes linked to cell death and negative regulation of apoptosis and microglial cell activation. |
2023-03-24 |
2023-08-14 |
rat |
| Yanfang Chen, Peng Ca. Circ-Bnc2 alleviates neuroinflammation in LPS-stimulated microglial cells to inhibit neuron cell apoptosis through regulating miR-497a-5p/HECTD1 axis. Brain and behavior. 2023-03-24. PMID:36960892. |
neuroinflammation caused by microglia cells activation and the apoptosis of neuron cells are associated with the occurrence of depression. |
2023-03-24 |
2023-08-14 |
mouse |
| Shengliang Peng, Yun Yu, Juan Li, Danling Jiang, Guohai Xu, Lidong Wu, Jialing H. Hsp22 pretreatment protection against LPS-induced hippocampal injury by alleviating neuroinflammation and apoptosis by regulating the NLRP3/Caspase1/IL-1β signaling pathway in mice. Aging. vol 15. 2023-03-19. PMID:36934348. |
preconditioning with the hsp22-overexpressing lentivirus attenuated lps-induced activation of hippocampal microglia, the expression of inflammatory factors and pathway proteins, and apoptosis, and improved cognitive impairment in mice. |
2023-03-19 |
2023-08-14 |
mouse |
| Moxin Wu, Zhiying Chen, Min Jiang, Bing Bao, Dongling Li, Xiaoping Yin, Xueren Wang, Dan Liu, Ling-Qiang Zh. Friend or foe: role of pathological tau in neuronal death. Molecular psychiatry. 2023-03-15. PMID:36918705. |
in contrast, pathological tau always detaches from microtubules and is implicated in a series of neurological disorders that are characterized by irreversible neuronal death, such as necrosis, apoptosis, necroptosis, pyroptosis, ferroptosis, autophagy-dependent neuronal death and phagocytosis by microglia. |
2023-03-15 |
2023-08-14 |
Not clear |
| Sepideh Ghazvineh, Morteza Salimi, Samaneh Dehghan, Azam Asemi-Rad, Kolsoum Dehdar, Alireza Salimi, Hamidreza Jamaati, Mohammad Reza Raouf. Stimulating olfactory epithelium mitigates mechanical ventilation-induced hippocampal inflammation and apoptosis. Hippocampus. 2023-03-03. PMID:36864704. |
we found that stimulating olfactory epithelium through applying rhythmic nasal ap, in association with reviving respiration-coupled brain rhythm, mitigates mv-induced hippocampal apoptosis and inflammation involving microglia and astrocytes. |
2023-03-03 |
2023-08-14 |
rat |