| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shinrye Lee, Jayoung Lee, Sangseop Kim, Jae-Yong Park, Won-Ha Lee, Kiyoshi Mori, Sang-Hyun Kim, In Kyeom Kim, Kyoungho Su. A dual role of lipocalin 2 in the apoptosis and deramification of activated microglia. Journal of immunology (Baltimore, Md. : 1950). vol 179. issue 5. 2007-11-20. PMID:17709539. |
the stable expression of lcn2 as well as the addition of rlcn2 protein augmented the sensitivity of microglia to the no-induced apoptosis, while knockdown of lcn2 expression using short hairpin rna attenuated the cell death. |
2007-11-20 |
2023-08-12 |
Not clear |
| Shinrye Lee, Jayoung Lee, Sangseop Kim, Jae-Yong Park, Won-Ha Lee, Kiyoshi Mori, Sang-Hyun Kim, In Kyeom Kim, Kyoungho Su. A dual role of lipocalin 2 in the apoptosis and deramification of activated microglia. Journal of immunology (Baltimore, Md. : 1950). vol 179. issue 5. 2007-11-20. PMID:17709539. |
thus, inflammatory activation of microglia may lead to up-regulation of lcn2 expression, which sensitizes microglia to the self-regulatory apoptosis. |
2007-11-20 |
2023-08-12 |
Not clear |
| Shinrye Lee, Jayoung Lee, Sangseop Kim, Jae-Yong Park, Won-Ha Lee, Kiyoshi Mori, Sang-Hyun Kim, In Kyeom Kim, Kyoungho Su. A dual role of lipocalin 2 in the apoptosis and deramification of activated microglia. Journal of immunology (Baltimore, Md. : 1950). vol 179. issue 5. 2007-11-20. PMID:17709539. |
taken together, our results suggest that activated microglia may secrete lcn2 protein, which act in an autocrine manner to sensitize microglia to the self-regulatory apoptosis and to endow microglia with an amoeboid form, a canonical morphology of activated microglia in vivo. |
2007-11-20 |
2023-08-12 |
Not clear |
| Rajagopal N Aravalli, Shuxian Hu, James R Lokensgar. Toll-like receptor 2 signaling is a mediator of apoptosis in herpes simplex virus-infected microglia. Journal of neuroinflammation. vol 4. 2007-11-05. PMID:17470292. |
toll-like receptor 2 signaling is a mediator of apoptosis in herpes simplex virus-infected microglia. |
2007-11-05 |
2023-08-12 |
Not clear |
| Aurel Popa-Wagner, Stanley Thomas Carmichael, Zaal Kokaia, Christof Kessler, Lary C Walke. The response of the aged brain to stroke: too much, too soon? Current neurovascular research. vol 4. issue 3. 2007-10-12. PMID:17691975. |
the early infarct in older rats is associated with a premature accumulation of brdu-positive microglia and astrocytes, persistence of activated oligodendrocytes, a high incidence of neuronal degeneration, and accelerated apoptosis. |
2007-10-12 |
2023-08-12 |
rat |
| Tracy Fischer-Smith, Jay Rappapor. Evolving paradigms in the pathogenesis of HIV-1-associated dementia. Expert reviews in molecular medicine. vol 7. issue 27. 2007-10-11. PMID:16321172. |
additionally, we explore mechanisms for neuronal injury and apoptosis, including the role of virus, viral and host proteins, oxidative stress and products of infected or uninfected activated microglia and astrocytes. |
2007-10-11 |
2023-08-12 |
Not clear |
| Kazuhide Inou. The function of microglia through purinergic receptors: neuropathic pain and cytokine release. Pharmacology & therapeutics. vol 109. issue 1-2. 2007-09-18. PMID:16169595. |
microglia are activated in threatened physiological homeostasis, including cns trauma, apoptosis, ischemia, inflammation, and infection. |
2007-09-18 |
2023-08-12 |
Not clear |
| Martin Wirenfeldt, Lasse Dissing-Olesen, Alicia Anne Babcock, Marianne Nielsen, Michael Meldgaard, Jens Zimmer, Iñigo Azcoitia, Robert Graham Quinton Leslie, Frederik Dagnaes-Hansen, Bente Finse. Population control of resident and immigrant microglia by mitosis and apoptosis. The American journal of pathology. vol 171. issue 2. 2007-09-13. PMID:17600121. |
population control of resident and immigrant microglia by mitosis and apoptosis. |
2007-09-13 |
2023-08-12 |
mouse |
| Martin Wirenfeldt, Lasse Dissing-Olesen, Alicia Anne Babcock, Marianne Nielsen, Michael Meldgaard, Jens Zimmer, Iñigo Azcoitia, Robert Graham Quinton Leslie, Frederik Dagnaes-Hansen, Bente Finse. Population control of resident and immigrant microglia by mitosis and apoptosis. The American journal of pathology. vol 171. issue 2. 2007-09-13. PMID:17600121. |
using bone marrow chimeric mice, we found that the lesion-induced proliferative capacity of resident microglia superseded that of immigrant microglia, whereas lesion-induced kinetics of apoptosis were comparable. |
2007-09-13 |
2023-08-12 |
mouse |
| Martin Wirenfeldt, Lasse Dissing-Olesen, Alicia Anne Babcock, Marianne Nielsen, Michael Meldgaard, Jens Zimmer, Iñigo Azcoitia, Robert Graham Quinton Leslie, Frederik Dagnaes-Hansen, Bente Finse. Population control of resident and immigrant microglia by mitosis and apoptosis. The American journal of pathology. vol 171. issue 2. 2007-09-13. PMID:17600121. |
these results broaden our understanding of the microglial response to neural damage by demonstrating that simultaneously occurring mitosis and apoptosis regulate expansion and reduction of both resident and immigrant microglial cell populations. |
2007-09-13 |
2023-08-12 |
mouse |
| Li-ping Yang, Ying Li, Xiu-an Zhu, Mark O M Ts. Minocycline delayed photoreceptor death in rds mice through iNOS-dependent mechanism. Molecular vision. vol 13. 2007-09-04. PMID:17653052. |
to elucidate the role of activated microglia and nitric oxide (no) in photoreceptor apoptosis in rds mice, and to investigate the effect of minocycline treatment on rds mice. |
2007-09-04 |
2023-08-12 |
mouse |
| Maoquan Li, Yanyan Wang, Ruiwei Guo, Yun Bai, Zhengping Y. Glucocorticoids impair microglia ability to induce T cell proliferation and Th1 polarization. Immunology letters. vol 109. issue 2. 2007-08-23. PMID:17360046. |
in addition, gc induced the apoptosis of microglia directly. |
2007-08-23 |
2023-08-12 |
Not clear |
| Tae Y Yune, Jee Y Lee, Gil Y Jung, Sun J Kim, Mei H Jiang, Young C Kim, Young J Oh, George J Markelonis, Tae H O. Minocycline alleviates death of oligodendrocytes by inhibiting pro-nerve growth factor production in microglia after spinal cord injury. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 29. 2007-08-23. PMID:17634369. |
here, we show that minocycline improves functional recovery after sci in part by reducing apoptosis of oligodendrocytes via inhibition of prongf production in microglia. |
2007-08-23 |
2023-08-12 |
Not clear |
| Nina Svoboda, Susanna Zierler, Hubert H Kerschbau. cAMP mediates ammonia-induced programmed cell death in the microglial cell line BV-2. The European journal of neuroscience. vol 25. issue 8. 2007-07-12. PMID:17445227. |
in the present study, we found that ammonia triggered mitosis at concentrations between 30 microm and 3.0 mm but apoptosis at concentrations >or= 1.0 mm in the murine microglial cell line bv-2. |
2007-07-12 |
2023-08-12 |
Not clear |
| Maarten Dewil, Vidal F dela Cruz, Ludo Van Den Bosch, Wim Robberech. Inhibition of p38 mitogen activated protein kinase activation and mutant SOD1(G93A)-induced motor neuron death. Neurobiology of disease. vol 26. issue 2. 2007-06-28. PMID:17346981. |
the p38 mapk-inhibitor, sb203580, completely inhibited mutant sod1-induced apoptosis of motor neurons and blocked lps-induced activation of microglia. |
2007-06-28 |
2023-08-12 |
mouse |
| Claudie Hooper, Jennifer M Pococ. Chromogranin A activates diverse pathways mediating inducible nitric oxide expression and apoptosis in primary microglia. Neuroscience letters. vol 413. issue 3. 2007-04-24. PMID:17267111. |
chromogranin a activates diverse pathways mediating inducible nitric oxide expression and apoptosis in primary microglia. |
2007-04-24 |
2023-08-12 |
rat |
| Claudie Hooper, Jennifer M Pococ. Chromogranin A activates diverse pathways mediating inducible nitric oxide expression and apoptosis in primary microglia. Neuroscience letters. vol 413. issue 3. 2007-04-24. PMID:17267111. |
in primary rat microglia, cga-mediated inducible nitric oxide (inos) expression, nitric oxide (no) production, mitochondrial depolarisation and apoptosis were inhibited by pp2 (src kinase inhibitor). |
2007-04-24 |
2023-08-12 |
rat |
| Ching-Liang Hsieh, Jyh-Jian Lin, Su-Yin Chiang, Shan-Yu Su, Nou-Ying Tang, Gaung-Geng Lin, I-Hsin Lin, Chung-Hsiang Liu, Chien-Yun Hsiang, Jaw-Chyun Chen, Tin-Yun H. Gastrodia elata modulated activator protein 1 via c-Jun N-terminal kinase signaling pathway in kainic acid-induced epilepsy in rats. Journal of ethnopharmacology. vol 109. issue 2. 2007-04-05. PMID:16934418. |
our previous study showed that gastrodia elata is able to reduce epileptic seizures, oxygen free radicals, microglia activation, and apoptosis in kainic acid (ka)-treated rats. |
2007-04-05 |
2023-08-12 |
rat |
| Rajagopal N Aravalli, Shuxian Hu, Timothy N Rowen, Genya Gekker, James R Lokensgar. Differential apoptotic signaling in primary glial cells infected with herpes simplex virus 1. Journal of neurovirology. vol 12. issue 6. 2007-01-30. PMID:17162665. |
the authors report that although apoptosis occurred rapidly in microglia, it was delayed during productive infection of astrocytes. |
2007-01-30 |
2023-08-12 |
Not clear |
| Bei Ping He, Jian Jun Wang, Xian Zhang, Yan Wu, Miao Wang, Boon-Huat Bay, Alex Yuang-Chi Chan. Differential reactions of microglia to brain metastasis of lung cancer. Molecular medicine (Cambridge, Mass.). vol 12. issue 7-8. 2007-01-26. PMID:17088948. |
the supernatant from lps-activated microglia induced apoptosis of metastatic lung cancer cells in vitro in a dose- and time-dependent manner. |
2007-01-26 |
2023-08-12 |
Not clear |