| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Dae Young Jung, Heasuk Lee, Kyoungho Su. Pro-apoptotic activity of N-myc in activation-induced cell death of microglia. Journal of neurochemistry. vol 94. issue 1. 2005-08-08. PMID:15953367. |
taken together, lps/ifngamma-induced n-myc participated in the activation-induced cell death of microglia by sensitizing the cells to no-induced apoptosis; however, n-myc did not influence the processes of inflammatory activation of microglia. |
2005-08-08 |
2023-08-12 |
Not clear |
| Nancy R Nichols, David Agolley, Malgorzata Zieba, Nicole By. Glucocorticoid regulation of glial responses during hippocampal neurodegeneration and regeneration. Brain research. Brain research reviews. vol 48. issue 2. 2005-07-15. PMID:15850668. |
corticosterone treatment prevented apoptosis, and decreased glial activation and the influx of activated microglia. |
2005-07-15 |
2023-08-12 |
rat |
| Dae Young Jung, Heasuk Lee, Bo-Young Jung, Jiyeon Ock, Myung-Shik Lee, Won-Ha Lee, Kyoungho Su. TLR4, but not TLR2, signals autoregulatory apoptosis of cultured microglia: a critical role of IFN-beta as a decision maker. Journal of immunology (Baltimore, Md. : 1950). vol 174. issue 10. 2005-07-05. PMID:15879150. |
tlr4, but not tlr2, signals autoregulatory apoptosis of cultured microglia: a critical role of ifn-beta as a decision maker. |
2005-07-05 |
2023-08-12 |
mouse |
| Dae Young Jung, Heasuk Lee, Bo-Young Jung, Jiyeon Ock, Myung-Shik Lee, Won-Ha Lee, Kyoungho Su. TLR4, but not TLR2, signals autoregulatory apoptosis of cultured microglia: a critical role of IFN-beta as a decision maker. Journal of immunology (Baltimore, Md. : 1950). vol 174. issue 10. 2005-07-05. PMID:15879150. |
in this study, we present evidence that tlr4, but not tlr2, mediates an autoregulatory apoptosis of activated microglia. |
2005-07-05 |
2023-08-12 |
mouse |
| Dae Young Jung, Heasuk Lee, Bo-Young Jung, Jiyeon Ock, Myung-Shik Lee, Won-Ha Lee, Kyoungho Su. TLR4, but not TLR2, signals autoregulatory apoptosis of cultured microglia: a critical role of IFN-beta as a decision maker. Journal of immunology (Baltimore, Md. : 1950). vol 174. issue 10. 2005-07-05. PMID:15879150. |
brain microglia underwent apoptosis upon stimulation with tlr4 ligand (lps), but not tlr2 ligands (pam(3)cys-ser-lys(4), peptidoglycan, and lipoteichoic acid). |
2005-07-05 |
2023-08-12 |
mouse |
| G M Sarra, F G Sarra, F C Schlichtenbrede, P Trittibach, S Estermann, E Tsiroukis, R R Ali, P J Luthert, M B Reiche. Effect of steroidal and non-steroidal drugs on the microglia activation pattern and the course of degeneration in the retinal degeneration slow mouse. Ophthalmic research. vol 37. issue 2. 2005-06-07. PMID:15746562. |
although this inflammatory process is not likely to be responsible for the onset of photoreceptor apoptosis, cytotoxic substances secreted by activated microglia could potentially accelerate and perpetuate the degenerative process. |
2005-06-07 |
2023-08-12 |
mouse |
| G M Sarra, F G Sarra, F C Schlichtenbrede, P Trittibach, S Estermann, E Tsiroukis, R R Ali, P J Luthert, M B Reiche. Effect of steroidal and non-steroidal drugs on the microglia activation pattern and the course of degeneration in the retinal degeneration slow mouse. Ophthalmic research. vol 37. issue 2. 2005-06-07. PMID:15746562. |
in this study we wanted to test the impact of the most commonly used anti-inflammatory drugs (acetylsalicylate and prednisolone) on the microglia activation pattern, the rate of caspase-3-dependent photoreceptor apoptosis and the course of the degeneration in the retinal degeneration slow (rds) mouse retina. |
2005-06-07 |
2023-08-12 |
mouse |
| Fernando Leonardi-Essmann, Michael Emig, Yoshihisa Kitamura, Rainer Spanagel, Peter J Gebicke-Haerte. Fractalkine-upregulated milk-fat globule EGF factor-8 protein in cultured rat microglia. Journal of neuroimmunology. vol 160. issue 1-2. 2005-04-28. PMID:15710462. |
these data provide a much closer look into molecular mechanisms involved in apoptosis of neurons and their removal by microglia. |
2005-04-28 |
2023-08-12 |
rat |
| Nahed S Elsisi, Selina Darling-Reed, Eunsook Y Lee, Ebenezer T Oriaku, Karam F Solima. Ibuprofen and apigenin induce apoptosis and cell cycle arrest in activated microglia. Neuroscience letters. vol 375. issue 2. 2005-04-22. PMID:15670648. |
ibuprofen and apigenin induce apoptosis and cell cycle arrest in activated microglia. |
2005-04-22 |
2023-08-12 |
Not clear |
| Kohichi Kawahara, Masataka Mori, Hitoshi Nakayam. [NO-induced apoptosis and ER stress in microglia]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 124. issue 6. 2005-04-05. PMID:15572844. |
[no-induced apoptosis and er stress in microglia]. |
2005-04-05 |
2023-08-12 |
mouse |
| Kohichi Kawahara, Masataka Mori, Hitoshi Nakayam. [NO-induced apoptosis and ER stress in microglia]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 124. issue 6. 2005-04-05. PMID:15572844. |
overactivation-induced apoptosis may be an essential self-regulatory mechanism for microglia in order to limit bystander killing of vulnerable neurons. |
2005-04-05 |
2023-08-12 |
mouse |
| Kuo-Sheng Hung, Shiuh-Lin Hwang, Chung-Ling Liang, Yann-Jang Chen, Tsung-Hsing Lee, Jong-Kang Liu, Shen-Long Howng, Cheng-Haung Wan. Calpain inhibitor inhibits p35-p25-Cdk5 activation, decreases tau hyperphosphorylation, and improves neurological function after spinal cord hemisection in rats. Journal of neuropathology and experimental neurology. vol 64. issue 1. 2005-03-03. PMID:15715081. |
in conclusion, mdl28170 abated calpain i activation, inhibited apoptosis and neuron loss, quenched microglia and astrocyte activation, and significantly improved neurologic deficit one week after spinal cord hemisection. |
2005-03-03 |
2023-08-12 |
rat |
| Wei Wang, Mark Solc, Ping Ji, Kimberly E Do. Corticotropin-releasing hormone potentiates neural injury induced by oxygen-glucose deprivation: a possible involvement of microglia. Neuroscience letters. vol 371. issue 2-3. 2005-01-25. PMID:15519743. |
however, when neurons were co-cultured with microglia, crh alone at concentrations greater than 100 nm induced neuronal apoptosis and crh potentiated significant neuronal apoptosis following exposure to ogd. |
2005-01-25 |
2023-08-12 |
Not clear |
| Wei Wang, Mark Solc, Ping Ji, Kimberly E Do. Corticotropin-releasing hormone potentiates neural injury induced by oxygen-glucose deprivation: a possible involvement of microglia. Neuroscience letters. vol 371. issue 2-3. 2005-01-25. PMID:15519743. |
these results suggest that crh potentiates neuronal apoptosis induced by ogd in the presence of microglia and that this effect may be mediated through the induction of proinflammatory mediators in microglia. |
2005-01-25 |
2023-08-12 |
Not clear |
| Gwenn A Garden, Weiqun Guo, Suman Jayadev, Christina Tun, Stephanie Balcaitis, Jo Choi, Thomas J Montine, Thomas Möller, Richard S Morriso. HIV associated neurodegeneration requires p53 in neurons and microglia. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 18. issue 10. 2005-01-05. PMID:15155568. |
using neuron/microglia co-culture of mixed p53 genotype, we observed that both neurons and microglia require p53 for gp120 induced neuronal apoptosis. |
2005-01-05 |
2023-08-12 |
mouse |
| Gye Sun Jeon, Tae-Cheon Kang, Sang Wook Park, Dong Woon Kim, Je Hoon Seo, Sa Sun Ch. Microglial responses in the avascular quail retina following transection of the optic nerve. Brain research. vol 1023. issue 1. 2004-12-21. PMID:15364014. |
on the other hand, tunel-positive microglia appeared in the gcl/nfl at later time points indicate that the decrease of microglial numbers is in part due to apoptosis in these layers. |
2004-12-21 |
2023-08-12 |
Not clear |
| M A Cosenza, M-L Zhao, S C Le. HIV-1 expression protects macrophages and microglia from apoptotic death. Neuropathology and applied neurobiology. vol 30. issue 5. 2004-12-15. PMID:15488024. |
these results suggest that hiv-1-infected macrophages and microglia are resistant to apoptosis, and may contribute to the formation of a central nervous system viral reservoir. |
2004-12-15 |
2023-08-12 |
Not clear |
| Katsura Takano, Yoichi Nakamura, Yukio Yoned. [Microglial cell death induced by polyamines]. Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology. vol 24. issue 4. 2004-11-30. PMID:15484815. |
these results suggest that particular polyamines induce cell death through apoptosis at low concentrations in cultured microglia |
2004-11-30 |
2023-08-12 |
rat |
| J Emerit, M Edeas, F Bricair. Neurodegenerative diseases and oxidative stress. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 58. issue 1. 2004-09-28. PMID:14739060. |
its role is pivotal for the modulation of critical cellular functions, notably for neurons astrocytes and microglia, such as apoptosis program activation, and ion transport, calcium mobilization, involved in excitotoxicity. |
2004-09-28 |
2023-08-12 |
Not clear |
| Gaia Novarino, Cinzia Fabrizi, Raffaella Tonini, Michela A Denti, Fiorella Malchiodi-Albedi, Giuliana M Lauro, Benedetto Sacchetti, Silvia Paradisi, Arnaldo Ferroni, Paul M Curmi, Samuel N Breit, Michele Mazzant. Involvement of the intracellular ion channel CLIC1 in microglia-mediated beta-amyloid-induced neurotoxicity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 23. 2004-09-24. PMID:15190104. |
we demonstrate that reducing clic1 chloride conductance by a specific blocker [iaa-94 (r(+)-[(6,7-dichloro-2-cyclopentyl-2,3-dihydro-2-methyl-1-oxo-1h-inden-5yl)-oxy] acetic acid)] prevents neuronal apoptosis in neurons cocultured with abeta-treated microglia. |
2004-09-24 |
2023-08-12 |
rat |