| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J Robertson, J M Beaulieu, M M Doroudchi, H D Durham, J P Julien, W E Mushynsk. Apoptotic death of neurons exhibiting peripherin aggregates is mediated by the proinflammatory cytokine tumor necrosis factor-alpha. The Journal of cell biology. vol 155. issue 2. 2001-12-04. PMID:11604419. |
apoptosis of drg neurons containing peripherin aggregates was dependent on the proinflammatory central nervous system environment of spinal cultures, rich in activated microglia, and required tnf-alpha. |
2001-12-04 |
2023-08-12 |
mouse |
| H Nakanishi, J Zhang, M Koike, T Nishioku, Y Okamoto, E Kominami, K von Figura, C Peters, K Yamamoto, P Saftig, Y Uchiyam. Involvement of nitric oxide released from microglia-macrophages in pathological changes of cathepsin D-deficient mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 19. 2001-10-11. PMID:11567042. |
these results suggest that no production via inos activity in microglia and peripheral macrophages contributes to secondary tissue damages such as neuronal apoptosis and intestinal necrosis, respectively. |
2001-10-11 |
2023-08-12 |
mouse |
| L Zheng, M A Calenoff, M C Dal Cant. Astrocytes, not microglia, are the main cells responsible for viral persistence in Theiler's murine encephalomyelitis virus infection leading to demyelination. Journal of neuroimmunology. vol 118. issue 2. 2001-09-20. PMID:11498260. |
in microglia, on the other hand, viral replication is restricted since only minimal amounts of negative rna copies can be demonstrated, while there are clear signs that some of these cells undergo apoptosis. |
2001-09-20 |
2023-08-12 |
mouse |
| J Y Wang, J M Yang, J Y Wang, P L Tao, S N Yan. Synergistic apoptosis induced by bacterial endotoxin lipopolysaccharide and high glucose in rat microglia. Neuroscience letters. vol 304. issue 3. 2001-08-30. PMID:11343831. |
synergistic apoptosis induced by bacterial endotoxin lipopolysaccharide and high glucose in rat microglia. |
2001-08-30 |
2023-08-12 |
rat |
| J Y Wang, J M Yang, J Y Wang, P L Tao, S N Yan. Synergistic apoptosis induced by bacterial endotoxin lipopolysaccharide and high glucose in rat microglia. Neuroscience letters. vol 304. issue 3. 2001-08-30. PMID:11343831. |
synergistic apoptosis of microglia was seen by lps in the presence of increased levels of d-glucose. |
2001-08-30 |
2023-08-12 |
rat |
| J Y Wang, J M Yang, J Y Wang, P L Tao, S N Yan. Synergistic apoptosis induced by bacterial endotoxin lipopolysaccharide and high glucose in rat microglia. Neuroscience letters. vol 304. issue 3. 2001-08-30. PMID:11343831. |
collectively, the present results suggest that increased ambient levels of glucose rendered microglia vulnerable to lps insults, and led to a synergistic apoptosis. |
2001-08-30 |
2023-08-12 |
rat |
| R S Nicholas, M G Wing, A Compsto. Nonactivated microglia promote oligodendrocyte precursor survival and maturation through the transcription factor NF-kappa B. The European journal of neuroscience. vol 13. issue 5. 2001-07-12. PMID:11264668. |
media conditioned by nonactivated microglia increase the number of surviving galactocerebroside(+) (galc(+)) oligodendrocytes in vitro at 48 h by inhibiting the apoptosis of opcs and stimulating their maturation to galc+ oligodendrocytes. |
2001-07-12 |
2023-08-12 |
rat |
| R S Nicholas, M G Wing, A Compsto. Nonactivated microglia promote oligodendrocyte precursor survival and maturation through the transcription factor NF-kappa B. The European journal of neuroscience. vol 13. issue 5. 2001-07-12. PMID:11264668. |
the use of antisense to the inhibitor of kappa binding (i kappa b) induces p65 subunit activation in opcs and, in common with medium conditioned by nonactivated microglia, also inhibits opc apoptosis and promotes cell maturation. |
2001-07-12 |
2023-08-12 |
rat |
| S Holman, P Collad. Postnatal cell proliferation and death in a lateralized, gender-related, asymmetric nucleus. Journal of neurobiology. vol 47. issue 2. 2001-06-21. PMID:11291103. |
we suggest that apoptosis, rather than neurogenesis, differentiates and lateralizes sdapc organization, and proliferating cells are microglia, phagocytosing debris. |
2001-06-21 |
2023-08-12 |
Not clear |
| H Kubová, R Druga, K Lukasiuk, L Suchomelová, R Haugvicová, I Jirmanová, A Pitkäne. Status epilepticus causes necrotic damage in the mediodorsal nucleus of the thalamus in immature rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 10. 2001-06-21. PMID:11331388. |
the presence of silver and fluoro-jade b-positive degenerating neurons in the mediodorsal thalamic nucleus was associated with the appearance of ox-42-immunopositive activated microglia but not with the expression of markers of programmed cell death, caspase-3, or cytochrome c. electron microscopy revealed necrosis of the ultrastructure of damaged neurons, providing further evidence that the mechanism of ste-induced damage in the mediodorsal thalamic nucleus at postnatal day 12 is necrosis rather than apoptosis. |
2001-06-21 |
2023-08-12 |
rat |
| C K Combs, J C Karlo, S C Kao, G E Landret. beta-Amyloid stimulation of microglia and monocytes results in TNFalpha-dependent expression of inducible nitric oxide synthase and neuronal apoptosis. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 4. 2001-06-07. PMID:11160388. |
beta-amyloid stimulation of microglia and monocytes results in tnfalpha-dependent expression of inducible nitric oxide synthase and neuronal apoptosis. |
2001-06-07 |
2023-08-12 |
mouse |
| D S Im, C E Heise, T Nguyen, B F O'Dowd, K R Lync. Identification of a molecular target of psychosine and its role in globoid cell formation. The Journal of cell biology. vol 153. issue 2. 2001-05-24. PMID:11309421. |
globoid cell leukodystrophy (gld) is characterized histopathologically by apoptosis of oligodendrocytes, progressive demyelination, and the existence of large, multinuclear (globoid) cells derived from perivascular microglia. |
2001-05-24 |
2023-08-12 |
Not clear |
| M Kaul, G A Garden, S A Lipto. Pathways to neuronal injury and apoptosis in HIV-associated dementia. Nature. vol 410. issue 6831. 2001-05-21. PMID:11309629. |
hiv-1 infects macrophages and microglia, but not neurons, although neurons are injured and die by apoptosis. |
2001-05-21 |
2023-08-12 |
human |
| B Liu, K Wang, H M Gao, B Mandavilli, J Y Wang, J S Hon. Molecular consequences of activated microglia in the brain: overactivation induces apoptosis. Journal of neurochemistry. vol 77. issue 1. 2001-05-03. PMID:11279274. |
molecular consequences of activated microglia in the brain: overactivation induces apoptosis. |
2001-05-03 |
2023-08-12 |
rat |
| B Liu, K Wang, H M Gao, B Mandavilli, J Y Wang, J S Hon. Molecular consequences of activated microglia in the brain: overactivation induces apoptosis. Journal of neurochemistry. vol 77. issue 1. 2001-05-03. PMID:11279274. |
furthermore, overactivation-induced apoptosis of microglia may be a fundamental self-regulatory mechanism devised to limit bystander killing of vulnerable neurons. |
2001-05-03 |
2023-08-12 |
rat |
| K A Jellinger, C H Stadelman. The enigma of cell death in neurodegenerative disorders. Journal of neural transmission. Supplementum. issue 60. 2001-04-12. PMID:11205141. |
apoptosis mainly involves reactive microglia and oligodendroglia, the latter often involved by deposits of insoluble fibrillary proteins, while alternative mechanisms of neuronal death may occur. |
2001-04-12 |
2023-08-12 |
human |
| P J Kingham, J M Pococ. Microglial secreted cathepsin B induces neuronal apoptosis. Journal of neurochemistry. vol 76. issue 5. 2001-04-05. PMID:11238732. |
conditioned medium from activated microglia or cathepsin b alone induced neuronal apoptosis and caspase 3 activation. |
2001-04-05 |
2023-08-12 |
Not clear |
| P J Kingham, J M Pococ. Microglial secreted cathepsin B induces neuronal apoptosis. Journal of neurochemistry. vol 76. issue 5. 2001-04-05. PMID:11238732. |
our data indicate that cga-activated microglia can trigger neuronal apoptosis and that this may be mediated through the secretion of cathepsin b. |
2001-04-05 |
2023-08-12 |
Not clear |
| M S Beattie, A A Farooqui, J C Bresnaha. Review of current evidence for apoptosis after spinal cord injury. Journal of neurotrauma. vol 17. issue 10. 2001-03-01. PMID:11063057. |
apoptosis occurs in populations of neurons, oligodendrocytes, microglia, and, perhaps, astrocytes. |
2001-03-01 |
2023-08-12 |
Not clear |
| M S Beattie, A A Farooqui, J C Bresnaha. Review of current evidence for apoptosis after spinal cord injury. Journal of neurotrauma. vol 17. issue 10. 2001-03-01. PMID:11063057. |
the mediators of apoptosis after sci are not well understood, but there is a close relationship between microglia and dying oligodendrocytes, suggesting that microglial activation may be involved. |
2001-03-01 |
2023-08-12 |
Not clear |