| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hüseyin Anıl Korkmaz, Raja Padidela, Behzat Ozka. Approach to nutritional rickets. Journal of pediatric endocrinology & metabolism : JPEM. 2023-02-27. PMID:36843296. |
rickets is the disease of a growing skeleton and results from impaired apoptosis of hypertrophic chondrocytes and mineralization of the growth plate. |
2023-02-27 |
2023-08-14 |
Not clear |
| Lifen Xu, Yuxia Zhou, Guifang Wang, Li Bo, Bangming Jin, Lujun Dai, Qinli Lu, Xueni Cai, Laying Hu, Lu Liu, Yixuan Wu, Xuebing Chang, Yali Huang, Lingyu Song, Tian Zhang, Yuanyuan Wang, Ying Xiao, Fan Zhang, Lingling Liu, Mingjun Shi, Tuanlao Wang, Bing Gu. The UDPase ENTPD5 regulates ER stress-associated renal injury by mediating protein N-glycosylation. Cell death & disease. vol 14. issue 2. 2023-02-27. PMID:36849424. |
overexpression of entpd5 relieved er stress in renal tubular cells, leading to compensatory cell proliferation that resulted in hypertrophy, while entpd5 knockdown aggravated er stress to induce cell apoptosis, leading to renal tubular atrophy and interstitial fibrosis. |
2023-02-27 |
2023-08-14 |
mouse |
| Jingyun Li, Yiliang Yin, Enyuan Zhang, Mang Gui, Ling Chen, Jun L. Peptide deregulated in hypertrophic scar-1 alleviates hypertrophic scar fibrosis by targeting focal adhesion kinase and pyruvate kinase M2 and remodeling the metabolic landscape. International journal of biological macromolecules. 2023-02-24. PMID:36828096. |
here, we demonstrate that a skin-derived endogenous peptide, peptide deregulated in hypertrophic scar-1 (pdhs1), with the sequence iatttasaataaaigatprak, inhibits cell proliferation, promotes apoptosis, decreases the proportion of cells in s phase, and decreases collagen synthesis in hypertrophic scar fibroblasts. |
2023-02-24 |
2023-08-14 |
rabbit |
| Anfal F Bin Dayel, Asma S Alonazi, Tahani K Alshammari, Nouf M Alrashee. P2X7 purinergic receptor: A potential target in heart diseases (Review). Molecular medicine reports. vol 27. issue 3. 2023-02-17. PMID:36799169. |
activation of these receptors can also contribute to the development of different types of cardiomyopathies including diabetic cardiomyopathy, dilated cardiomyopathy and hypertrophic cardiomyopathy by inducing cardiac hypertrophy, fibrosis and apoptosis. |
2023-02-17 |
2023-08-14 |
Not clear |
| Ya-Wen Deng, Fei Liu, Zhi-Tong Li, Jing-Han Gao, Yong Zhao, Xiao-Lei Yang, Yun-Long Xi. Hyperglycemia promotes myocardial dysfunction via the ERS-MAPK10 signaling pathway in db/db mice. Laboratory investigation; a journal of technical methods and pathology. vol 102. issue 11. 2023-02-12. PMID:36775445. |
similarly, tail vein injection of raav9-sh-mapk10 reversed the phenotype of the heart in db/db mice including cardiac hypertrophy and apoptosis in db/db mice. |
2023-02-12 |
2023-08-14 |
mouse |
| Xi He, Si Yang, Juan Deng, Qing Wu, Wei-Jin Zan. Amelioration of circadian disruption and calcium-handling protein defects by choline alleviates cardiac remodeling in abdominal aorta coarctation rats. Laboratory investigation; a journal of technical methods and pathology. vol 101. issue 7. 2023-02-12. PMID:36775558. |
the key pathophysiological process leading to heart failure is cardiac remodeling, a term referring to cardiac hypertrophy, fibrosis, and apoptosis. |
2023-02-12 |
2023-08-14 |
rat |
| Ruiqi Hao, Chun Wang, Chen Yang, Jiang Chang, Xiqiao Wang, Bo Yuan, Haiting Xu, Sen Zhou, Chen Fan, Zhiming L. Transdermal delivery of Protocatechuic aldehyde using hyaluronic acid/gelatin-based microneedles for the prevention and treatment of hypertrophic scars. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 2023-02-11. PMID:36773724. |
the formation of hypertrophic scar (hs) involves many pathological processes, such as reduced apoptosis in fibroblasts, excessive collagen deposition by fibroblasts, over-abundant angiogenesis, etc. |
2023-02-11 |
2023-08-14 |
human |
| Ilitch Aquino Marcondes-de-Castro, Thamiris Ferreira Oliveira, Renata Spezani, Thatiany Souza Marinho, Luiz Macedo Cardoso, Marcia Barbosa Aguila, Carlos Alberto Mandarim-de-Lacerd. Cotadutide effect in liver and adipose tissue in obese mice. Journal of molecular endocrinology. 2023-02-08. PMID:36753306. |
in addition, cotadutide improved lipid metabolism genes in ewat, fatty acid synthase, peroxisome proliferator-activated receptor gamma, and mitigates adipocyte hypertrophy and apoptosis. |
2023-02-08 |
2023-08-14 |
mouse |
| Ilitch Aquino Marcondes-de-Castro, Thamiris Ferreira Oliveira, Renata Spezani, Thatiany Souza Marinho, Luiz Macedo Cardoso, Marcia Barbosa Aguila, Carlos Alberto Mandarim-de-Lacerd. Cotadutide effect in liver and adipose tissue in obese mice. Journal of molecular endocrinology. 2023-02-08. PMID:36753306. |
besides, in adipocytes, cotadutide decreases hypertrophy and reduces apoptosis. |
2023-02-08 |
2023-08-14 |
mouse |
| Qiaoling Li, Bowei Zhang, Jie Lu, Qingbiao Wa, Mei He, Lixia Xie, Lei Zhan. SNHG1 functions as a ceRNA in hypertrophic scar fibroblast proliferation and apoptosis through miR-320b/CTNNB1 axis. Archives of dermatological research. 2023-02-08. PMID:36754869. |
snhg1 functions as a cerna in hypertrophic scar fibroblast proliferation and apoptosis through mir-320b/ctnnb1 axis. |
2023-02-08 |
2023-08-14 |
Not clear |
| Yiman Chen, Huihui Deng, Liya Yang, Ling Guo, Min Fen. Desferrioxamine enhances 5-aminolaevulinic acid- induced protoporphyrin IX accumulation and therapeutic efficacy for hypertrophic scar. Journal of pharmaceutical sciences. 2023-01-22. PMID:36682488. |
in vitro experiments showed that 5-ala/dfo could increase more ros generation by increasing the accumulation of ppix, resulting in the apoptosis of hypertrophic scar fibroblasts. |
2023-01-22 |
2023-08-14 |
Not clear |
| Ruifang Chi, Chanjuan Chai, Gaizhen Liu, Huili Cao, Bin Yan. Chronic intermittent hypoxia-induced BNIP3 expression mitigates contractile dysfunction and myocardial injury in animal and cell model via modulating autophagy. Human cell. 2023-01-10. PMID:36627546. |
knockout of bnip3 significantly aggravated the impairment in cardiac function, apoptosis, oxidative stress, and hypertrophy of cih rats, while significantly reducing autophagy. |
2023-01-10 |
2023-08-14 |
rat |
| Guoqing Li, Su Liu, Huihui Xu, Yixiao Chen, Jiapeng Deng, Ao Xiong, Deli Wang, Jian Weng, Fei Yu, Liang Gao, Changhai Ding, Hui Zen. Potential effects of teriparatide (PTH (1-34)) on osteoarthritis: a systematic review. Arthritis research & therapy. vol 25. issue 1. 2023-01-07. PMID:36609338. |
in vitro studies (n = 11) concluded that pth (1-34) was important for chondrocytes via increasing the proliferation and matrix synthesis but preventing apoptosis or hypertrophy. |
2023-01-07 |
2023-08-14 |
Not clear |
| Shiyi Li, Jinxiu Yang, Jiachen Sun, Minliang Che. Adipose-Derived Mesenchymal Stem Cells Alleviate Hypertrophic Scar by Inhibiting Bioactivity and Inducing Apoptosis in Hypertrophic Scar Fibroblasts. Cells. vol 11. issue 24. 2022-12-23. PMID:36552789. |
adipose-derived mesenchymal stem cells alleviate hypertrophic scar by inhibiting bioactivity and inducing apoptosis in hypertrophic scar fibroblasts. |
2022-12-23 |
2023-08-14 |
Not clear |
| Yanxia Zhu, Qi Jiang, Zhaokui Jin, Danyang Chen, Qingqing Xu, Jinchun Chen, Yue Zeng, Shengqiang Chen, Qianjun H. Two-Dimensional Mg Advanced healthcare materials. 2022-12-22. PMID:36546774. |
two-dimensional mg unexpected temporal and spatial extension of inflammation in severely burned patients frequently causes cellular apoptosis, wound deepening, and serious fibroplasia, leading to the difficulty of wound healing and the formation of hypertrophic scar. |
2022-12-22 |
2023-08-14 |
Not clear |
| Wang Gu, Qiang Bao, Kaiqi Weng, Jinlu Liu, Shuwen Luo, Jianzhou Chen, Zheng Li, Zhengfeng Cao, Yu Zhang, Yang Zhang, Guohong Chen, Qi X. Effects of T-2 toxin on growth performance, feather quality, tibia development and blood parameters in Yangzhou goslings. Poultry science. vol 102. issue 2. 2022-12-19. PMID:36535114. |
we also found that hypertrophic chondrocytes of the tibial growth plate exhibited abnormal morphology and nuclear consolidation or loss, accompanied by necrosis and excessive apoptosis under 2.0 mg/kg t-2 toxin exposure. |
2022-12-19 |
2023-08-14 |
Not clear |
| Zhencheng Yu, Yun Li, Rao Fu, Yaxin Xue, Danyang Zhao, Dong Ha. Platycodin D inhibits the proliferation and migration of hypertrophic scar-derived fibroblasts and promotes apoptosis through a caspase-dependent pathway. Archives of dermatological research. 2022-12-16. PMID:36526799. |
platycodin d inhibits the proliferation and migration of hypertrophic scar-derived fibroblasts and promotes apoptosis through a caspase-dependent pathway. |
2022-12-16 |
2023-08-14 |
human |
| Juin Maity, Tiyasa Dey, Adrita Banerjee, Aindrila Chattopadhyay, Asish R Das, Debasish Bandyopadhya. Melatonin ameliorates myocardial infarction in obese diabetic individuals: the possible involvement of macrophage apoptotic factors. Journal of pineal research. 2022-12-01. PMID:36456538. |
the accelerated oxidative stress and pro-inflammatory response induced cardiomyocyte hypertrophy, followed by apoptosis in obese diabetic individuals causes progression of athero-thrombotic vascular disease. |
2022-12-01 |
2023-08-14 |
Not clear |
| Grażyna Sygitowicz, Dariusz Sitkiewic. Involvement of circRNAs in the Development of Heart Failure. International journal of molecular sciences. vol 23. issue 22. 2022-11-26. PMID:36430607. |
recent studies indicate a key role of circrna in cardiomyocyte hypertrophy, fibrosis, autophagy and apoptosis. |
2022-11-26 |
2023-08-14 |
Not clear |
| Runran Miao, Libo Wang, Zhigang Chen, Shiqi Ge, Li Li, Kai Zhang, Yingen Chen, Wenjing Guo, Xulei Duan, Mingyang Zhu, Guoan Zhao, Fei Li. Advances in the study of nicotinamide adenine dinucleotide phosphate oxidase in myocardial remodeling. Frontiers in cardiovascular medicine. vol 9. 2022-11-21. PMID:36407440. |
during chronic stress, the heart undergoes myocardial remodeling, mainly manifested by cardiomyocyte hypertrophy, apoptosis, interstitial fibrosis, chamber enlargement, and cardiac dysfunction. |
2022-11-21 |
2023-08-14 |
human |