| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sandra Garoby-Salom, Myriam Rouahi, Elodie Mucher, Nathalie Auge, Robert Salvayre, Anne Negre-Salvayr. Hyaluronan synthase-2 upregulation protects smpd3-deficient fibroblasts against cell death induced by nutrient deprivation, but not against apoptosis evoked by oxidized LDL. Redox biology. vol 4. 2016-06-10. PMID:25555205. |
these mice exhibit a severe neonatal dysplasia, a lack of long bone mineralization and delayed apoptosis patterns of hypertrophic chondrocytes in the growth plate. |
2016-06-10 |
2023-08-13 |
mouse |
| Sandra Garoby-Salom, Myriam Rouahi, Elodie Mucher, Nathalie Auge, Robert Salvayre, Anne Negre-Salvayr. Hyaluronan synthase-2 upregulation protects smpd3-deficient fibroblasts against cell death induced by nutrient deprivation, but not against apoptosis evoked by oxidized LDL. Redox biology. vol 4. 2016-06-10. PMID:25555205. |
taken together, these results highlight the role of nsmase2 in apoptosis evoked by nutrient starvation that could contribute to the delayed apoptosis of hypertrophic chondrocytes in the growth plate, and emphasize the antiapoptotic properties of has2. |
2016-06-10 |
2023-08-13 |
mouse |
| Qianqian Gao, Lina Guan, Shanshan Hu, Yanwei Yao, Xiaolin Ren, Zhenwei Zhang, Canling Cheng, Yi Liu, Chun Zhang, Jinpeng Huang, Dongmei Su, Xu M. Study on the mechanism of HIF1a-SOX9 in glucose-induced cardiomyocyte hypertrophy. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 74. 2016-06-08. PMID:26349963. |
the results showed that cardiomyocytes cultured with 25mm glucose tended to show a hypertrophic phenotype, while cardiomyocytes cultured with 35mm glucose tended to undergo apoptosis. |
2016-06-08 |
2023-08-13 |
Not clear |
| Eva S Liu, Adalbert Raimann, Byongsoo Timothy Chae, Janaina S Martins, Manuela Baccarini, Marie B Dema. c-Raf promotes angiogenesis during normal growth plate maturation. Development (Cambridge, England). vol 143. issue 2. 2016-05-23. PMID:26657770. |
extracellular phosphate plays a key role in growth plate maturation by inducing erk1/2 (mapk3/1) phosphorylation, leading to hypertrophic chondrocyte apoptosis. |
2016-05-23 |
2023-08-13 |
mouse |
| Eva S Liu, Adalbert Raimann, Byongsoo Timothy Chae, Janaina S Martins, Manuela Baccarini, Marie B Dema. c-Raf promotes angiogenesis during normal growth plate maturation. Development (Cambridge, England). vol 143. issue 2. 2016-05-23. PMID:26657770. |
in vivo studies demonstrated that loss of c-raf in chondrocytes leads to expansion of the hypertrophic layer of the growth plate, with decreased phospho-erk1/2 immunoreactivity and impaired hypertrophic chondrocyte apoptosis. |
2016-05-23 |
2023-08-13 |
mouse |
| Aramita Ray, Santanu Rana, Durba Banerjee, Arkadeep Mitra, Ritwik Datta, Shaon Naskar, Sagartirtha Sarka. Improved bioavailability of targeted Curcumin delivery efficiently regressed cardiac hypertrophy by modulating apoptotic load within cardiac microenvironment. Toxicology and applied pharmacology. vol 290. 2016-05-10. PMID:26612707. |
cardiomyocyte apoptosis acts as a prime modulator of cardiac hypertrophy leading to heart failure, a major cause of human mortality worldwide. |
2016-05-10 |
2023-08-13 |
human |
| Lorna Daniels, James R Bell, Lea M D Delbridge, Fiona J McDonald, Regis R Lamberts, Jeffrey R Erickso. The role of CaMKII in diabetic heart dysfunction. Heart failure reviews. vol 20. issue 5. 2016-05-09. PMID:26198034. |
camkiiδ activity is up-regulated in the myocardium of diabetic patients and mouse models of diabetes, where it promotes pathological signaling that includes hypertrophy, fibrosis and apoptosis. |
2016-05-09 |
2023-08-13 |
mouse |
| Lorna Daniels, James R Bell, Lea M D Delbridge, Fiona J McDonald, Regis R Lamberts, Jeffrey R Erickso. The role of CaMKII in diabetic heart dysfunction. Heart failure reviews. vol 20. issue 5. 2016-05-09. PMID:26198034. |
pharmacological inhibition and knockout models of camkiiδ have shown some promise of a potential therapeutic benefit of camkiiδ inhibition, with protection against cardiac hypertrophy and apoptosis reported. |
2016-05-09 |
2023-08-13 |
mouse |
| Serkan Kemer, Ferhan Karademir, Gokhan Aydemir, Zafer Kucukodaci, Ozgur Pirgon, F Alparslan Genc, Secil Aydino. Effects of Inhaled Corticosteroids on the Growth Plates of Infant Rats. Fetal and pediatric pathology. vol 34. issue 4. 2016-05-03. PMID:26035745. |
growth cartilage chondrocyte proliferation and apoptosis rates; igf-1 and glucocorticoid receptor levels; and resting, proliferative, hypertrophic, and total zone (tz) measurements were compared using immunohistochemical-staining methods. |
2016-05-03 |
2023-08-13 |
rat |
| Wei-Wei Wang, Fei-Long Zhang, Jian-Hua Chen, Xue-Hai Chen, Fa-Yuan Fu, Mi-Rong Tang, Liang-Long Che. Telmisartan reduces atrial arrhythmia susceptibility through the regulation of RAS-ERK and PI3K-Akt-eNOS pathways in spontaneously hypertensive rats. Canadian journal of physiology and pharmacology. vol 93. issue 8. 2016-05-03. PMID:26158699. |
arrhythmogenic atrial remodeling, including enlargement of the left atrium, myocyte hypertrophy, interstitial fibrosis, and myocyte apoptosis, was observed in the shr group, and was accompanied by activated ras-erk signaling and suppressed pi3k-akt-enos signaling. |
2016-05-03 |
2023-08-13 |
rat |
| Nakshi Sinha, Pradeep Kumar Dabl. Oxidative stress and antioxidants in hypertension-a current review. Current hypertension reviews. vol 11. issue 2. 2016-04-27. PMID:26022210. |
oxidative stress is found to be associated with endothelial dysfunction, inflammation, hypertrophy, apoptosis, cell migration, fibrosis, and angiogenesis in relation to vascular remodelling of hypertension. |
2016-04-27 |
2023-08-13 |
Not clear |
| Mario Notari, Julián Pulecio, Ángel Ray. Update on the Pathogenic Implications and Clinical Potential of microRNAs in Cardiac Disease. BioMed research international. vol 2015. 2016-04-21. PMID:26221581. |
for instance, acute myocardial infarction induces cardiac tissue necrosis and apoptosis but also initiates a pathological remodelling response of the left ventricle that includes hypertrophic growth of cardiomyocytes and fibrotic deposition of extracellular matrix components. |
2016-04-21 |
2023-08-13 |
Not clear |
| J H Park, J H Lee, J-W Par. Attenuated SAG expression exacerbates 4-hydroxy-2-nonenal-induced apoptosis and hypertrophy of H9c2 cardiomyocytes. Free radical research. vol 49. issue 8. 2016-04-18. PMID:25850934. |
attenuated sag expression exacerbates 4-hydroxy-2-nonenal-induced apoptosis and hypertrophy of h9c2 cardiomyocytes. |
2016-04-18 |
2023-08-13 |
Not clear |
| J H Park, J H Lee, J-W Par. Attenuated SAG expression exacerbates 4-hydroxy-2-nonenal-induced apoptosis and hypertrophy of H9c2 cardiomyocytes. Free radical research. vol 49. issue 8. 2016-04-18. PMID:25850934. |
in the present study, we showed that the transfection of h9c2 clonal myoblastic cells with small interfering rna (sirna) specific for sag markedly attenuated sag expression and exacerbates hne-induced apoptosis and hypertrophy. |
2016-04-18 |
2023-08-13 |
Not clear |
| J H Park, J H Lee, J-W Par. Attenuated SAG expression exacerbates 4-hydroxy-2-nonenal-induced apoptosis and hypertrophy of H9c2 cardiomyocytes. Free radical research. vol 49. issue 8. 2016-04-18. PMID:25850934. |
taken together, our results showed that the suppression of sag expression by sirna enhanced hne-induced apoptosis and hypertrophy of cultured cardiomyocytes via the disruption of the cellular redox balance. |
2016-04-18 |
2023-08-13 |
Not clear |
| Chen Fan, Yan Xie, Ying Dong, Yonghua Su, Zee Upto. Investigating the potential of Shikonin as a novel hypertrophic scar treatment. Journal of biomedical science. vol 22. 2016-04-18. PMID:26275605. |
our previous studies indicated that shikonin, an active component extracted from radix arnebiae, induces apoptosis and reduces collagen production in hypertrophic scar-derived fibroblasts. |
2016-04-18 |
2023-08-13 |
Not clear |
| Merih Önal, Taner Yılmaz, Elif Bilgiç, Sevda Müftüoğlu, Tevfik Sözen, Münir Demir Baji. Possible role of apoptosis in pathogenesis of adenoid hypertrophy and chronic adenoiditis: Prospective case-control study. Auris, nasus, larynx. vol 42. issue 6. 2016-04-14. PMID:26003878. |
possible role of apoptosis in pathogenesis of adenoid hypertrophy and chronic adenoiditis: prospective case-control study. |
2016-04-14 |
2023-08-13 |
Not clear |
| Merih Önal, Taner Yılmaz, Elif Bilgiç, Sevda Müftüoğlu, Tevfik Sözen, Münir Demir Baji. Possible role of apoptosis in pathogenesis of adenoid hypertrophy and chronic adenoiditis: Prospective case-control study. Auris, nasus, larynx. vol 42. issue 6. 2016-04-14. PMID:26003878. |
the aim of this study is to investigate the role of apoptosis in chronic adenoiditis and adenoid hypertrophy. |
2016-04-14 |
2023-08-13 |
Not clear |
| Merih Önal, Taner Yılmaz, Elif Bilgiç, Sevda Müftüoğlu, Tevfik Sözen, Münir Demir Baji. Possible role of apoptosis in pathogenesis of adenoid hypertrophy and chronic adenoiditis: Prospective case-control study. Auris, nasus, larynx. vol 42. issue 6. 2016-04-14. PMID:26003878. |
this is the first study in the literature about apoptosis in adenoid hypertrophy and chronic adenoiditis. |
2016-04-14 |
2023-08-13 |
Not clear |
| Dong Zheng, Jian Ma, Yong Yu, Minghui Li, Rui Ni, Grace Wang, Ruizhen Chen, Jianmin Li, Guo-Chang Fan, James C Lacefield, Tianqing Pen. Silencing of miR-195 reduces diabetic cardiomyopathy in C57BL/6 mice. Diabetologia. vol 58. issue 8. 2016-04-13. PMID:25994075. |
inhibition of mir-195 prevents apoptosis in cardiomyocytes stimulated with palmitate and transgenic overexpression of mir-195 induces cardiac hypertrophy and heart failure. |
2016-04-13 |
2023-08-13 |
mouse |