| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sarita Nehra, Varun Bhardwaj, Namita Kalra, Lilly Ganju, Anju Bansal, Shweta Saxena, Deepika Saraswa. Nanocurcumin protects cardiomyoblasts H9c2 from hypoxia-induced hypertrophy and apoptosis by improving oxidative balance. Journal of physiology and biochemistry. vol 71. issue 2. 2016-02-17. PMID:25846484. |
h9c2 cardiomyoblasts were challenged with 0.5 % oxygen, for 24 h to assess hypoxia-induced oxidative damage, hypertrophy and consequent apoptosis. |
2016-02-17 |
2023-08-13 |
Not clear |
| Sarita Nehra, Varun Bhardwaj, Namita Kalra, Lilly Ganju, Anju Bansal, Shweta Saxena, Deepika Saraswa. Nanocurcumin protects cardiomyoblasts H9c2 from hypoxia-induced hypertrophy and apoptosis by improving oxidative balance. Journal of physiology and biochemistry. vol 71. issue 2. 2016-02-17. PMID:25846484. |
nanocurcumin ameliorated hypoxia-induced hypertrophy and apoptosis in h9c2 cells significantly (p ≤ 0.01), by downregulating atrial natriuretic factor expression, caspase-3/-7 activation, oxidative stress and stabilizing hypoxia-inducible factor-1α (hif-1α) better than curcumin. |
2016-02-17 |
2023-08-13 |
Not clear |
| Ping Li, Quan-Yong He, Cheng-Qun Lu. Overexpression of miR-200b inhibits the cell proliferation and promotes apoptosis of human hypertrophic scar fibroblasts in vitro. The Journal of dermatology. vol 41. issue 10. 2016-02-16. PMID:25228082. |
overexpression of mir-200b inhibits the cell proliferation and promotes apoptosis of human hypertrophic scar fibroblasts in vitro. |
2016-02-16 |
2023-08-13 |
human |
| Ping Li, Quan-Yong He, Cheng-Qun Lu. Overexpression of miR-200b inhibits the cell proliferation and promotes apoptosis of human hypertrophic scar fibroblasts in vitro. The Journal of dermatology. vol 41. issue 10. 2016-02-16. PMID:25228082. |
we also found that mir-200b affected hypertrophic scarring through regulating the cell proliferation and apoptosis of human hypertrophic scar fibroblasts by affecting the collagen i and iii synthesis, fibronectin expression and tgf-β1/α-sma signaling. |
2016-02-16 |
2023-08-13 |
human |
| Subbiah Ramasamy, Ganesan Velmurugan, K Shanmugha Rajan, Tharmarajan Ramprasath, Krishnan Kalpan. MiRNAs with apoptosis regulating potential are differentially expressed in chronic exercise-induced physiologically hypertrophied hearts. PloS one. vol 10. issue 3. 2016-02-09. PMID:25793527. |
chronic swimming protocol continuously for eight weeks resulted in induction of physiological hypertrophy in rats and histopathology revealed the absence of tissue damage, apoptosis or fibrosis. |
2016-02-09 |
2023-08-13 |
rat |
| Subbiah Ramasamy, Ganesan Velmurugan, K Shanmugha Rajan, Tharmarajan Ramprasath, Krishnan Kalpan. MiRNAs with apoptosis regulating potential are differentially expressed in chronic exercise-induced physiologically hypertrophied hearts. PloS one. vol 10. issue 3. 2016-02-09. PMID:25793527. |
in summary, our data indicates that regulation of these mirnas with apoptosis regulating potential can be one of the major key factors in determining pathological or physiological hypertrophy by controlling fibrosis, apoptosis and cell death mechanisms. |
2016-02-09 |
2023-08-13 |
rat |
| Dennis Jine-Yuan Hsieh, Wei-Wen Kuo, Yi-Ping Lai, Marthandam Asokan Shibu, Chia-Yao Shen, Peiying Pai, Yu-Lan Yeh, Jing-Ying Lin, Vijaya Padma Viswanadha, Chih-Yang Huan. 17β-Estradiol and/or Estrogen Receptor β Attenuate the Autophagic and Apoptotic Effects Induced by Prolonged Hypoxia Through HIF-1α-Mediated BNIP3 and IGFBP-3 Signaling Blockage. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. vol 36. issue 1. 2016-02-09. PMID:25967966. |
we previously demonstrated that 17β-estradiol (e2) prevents cardiomyocyte hypertrophy, autophagy and apoptosis via estrogen receptor α (erα), but the effects of erβ on myocardial injury remained elusive. |
2016-02-09 |
2023-08-13 |
Not clear |
| J Fuentes-Antrás, B Picatoste, A Gómez-Hernández, J Egido, J Tuñón, Ó Lorenz. Updating experimental models of diabetic cardiomyopathy. Journal of diabetes research. vol 2015. 2016-02-09. PMID:25973429. |
inflammation, hypertrophy, fibrosis, steatosis, and apoptosis in the myocardium have been studied in numerous diabetic experimental models in animals, mostly rodents. |
2016-02-09 |
2023-08-13 |
human |
| Yuanyuan Qian, Peng Zhong, Dandan Liang, Zheng Xu, Melissa Skibba, Chunlai Zeng, Xiaokun Li, Tiemin Wei, Lianpin Wu, Guang Lian. A newly designed curcumin analog Y20 mitigates cardiac injury via anti-inflammatory and anti-oxidant actions in obese rats. PloS one. vol 10. issue 3. 2016-02-08. PMID:25786209. |
in high fat diet-fed rats, oral administration of y20 at 20 mg/kg or curcumin at 50 mg/kg significantly decreased the cardiac inflammation and oxidative stress and eventually improved the cardiac remodeling by mitigating cardiac disorganization, hypertrophy, fibrosis and apoptosis. |
2016-02-08 |
2023-08-13 |
human |
| Kun Yin, Liang Zhao, Dan Feng, Wenya Ma, Yu Liu, Yang Wang, Jing Liang, Fan Yang, Chongwei Bi, Hongyang Chen, Xingda Li, Yanjie Lu, Benzhi Ca. Resveratrol Attenuated Low Ambient Temperature-Induced Myocardial Hypertrophy via Inhibiting Cardiomyocyte Apoptosis. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. vol 35. issue 6. 2016-02-08. PMID:25967874. |
resveratrol attenuated low ambient temperature-induced myocardial hypertrophy via inhibiting cardiomyocyte apoptosis. |
2016-02-08 |
2023-08-13 |
mouse |
| Shouji Matsushima, Junichi Sadoshim. The role of sirtuins in cardiac disease. American journal of physiology. Heart and circulatory physiology. vol 309. issue 9. 2016-02-08. PMID:26232232. |
sirt6 has also recently been demonstrated to attenuate cardiac hypertrophy, and sirt7 is known to regulate apoptosis and stress responses in the heart. |
2016-02-08 |
2023-08-13 |
Not clear |
| Heng Zeng, Lanfang Li, Jian-Xiong Che. Loss of Sirt3 limits bone marrow cell-mediated angiogenesis and cardiac repair in post-myocardial infarction. PloS one. vol 9. issue 9. 2016-02-04. PMID:25192254. |
bmc treatment also attenuated nadph oxidase subunits p47phox and gp91phox expression, and significantly reduced ros formation, apoptosis, fibrosis and hypertrophy in post-mi mice. |
2016-02-04 |
2023-08-13 |
mouse |
| Shaon Naskar, Kaberi Datta, Arkadeep Mitra, Kanchan Pathak, Ritwik Datta, Trisha Bansal, Sagartirtha Sarka. Differential and conditional activation of PKC-isoforms dictates cardiac adaptation during physiological to pathological hypertrophy. PloS one. vol 9. issue 8. 2016-02-02. PMID:25116170. |
pkc-δ activation during pathological hypertrophy resulted in cardiomyocyte apoptosis leading to compromised cardiac function and on the other hand, activation of pkc-α during physiological hypertrophy promoted cardiomyocyte growth but down regulated cellular apoptotic load resulting in improved cardiac function. |
2016-02-02 |
2023-08-13 |
mouse |
| Kuan-Ho Lin, Chia-Hua Kuo, Wei-Wen Kuo, Tsung-Jung Ho, Peiying Pai, Wei-Kung Chen, Lung-Fa Pan, Chien-Cheng Wang, V Vijaya Padma, Chih-Yang Huan. NFIL3 suppresses hypoxia-induced apoptotic cell death by targeting the insulin-like growth factor 2 receptor. Journal of cellular biochemistry. vol 116. issue 6. 2016-01-25. PMID:25536374. |
the igf2r is not only an igf2 clearance receptor, but it also triggers signal transduction, resulting in cardiac hypertrophy, apoptosis and fibrosis. |
2016-01-25 |
2023-08-13 |
rat |
| Young Woo Eom, Ha Yun Jung, Ji-Eun Oh, Jun-Won Lee, Min-Soo Ahn, Young Jin Youn, Sung Gyun Ahn, Jang Young Kim, Seung-Hwan Lee, Junghan Yoon, Byung-Su Yo. Isoproterenol Enhances Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand-Induced Apoptosis in Human Embryonic Kidney Cells through Death Receptor 5 up-Regulation. Korean circulation journal. vol 46. issue 1. 2016-01-22. PMID:26798390. |
chronic impairment of β-adrenergic receptor signaling increases cardiac apoptosis, hypertrophy and fibrosis. |
2016-01-22 |
2023-08-13 |
human |
| Yingying Sun, Tong Zhang, Li Li, Ji Wan. Induction of apoptosis by hypertension via endoplasmic reticulum stress. Kidney & blood pressure research. vol 40. issue 1. 2016-01-15. PMID:25791362. |
however, the mechanisms by which er stress leads to apoptosis remain enigmatic, particularly in the progression from cardiac hypertrophy to diastolic heart failure due to hypertension. |
2016-01-15 |
2023-08-13 |
Not clear |
| Wei Lv, Jingqiu Lou, Yan Zhang, Peiwen Lian, Dong Qi, Jianping Wan. Mycophenolate mofetil inhibits hypertrophy and apoptosis of podocyte in vivo and in vitro. International journal of clinical and experimental medicine. vol 8. issue 10. 2016-01-15. PMID:26770644. |
mycophenolate mofetil inhibits hypertrophy and apoptosis of podocyte in vivo and in vitro. |
2016-01-15 |
2023-08-13 |
Not clear |
| Wei Lv, Jingqiu Lou, Yan Zhang, Peiwen Lian, Dong Qi, Jianping Wan. Mycophenolate mofetil inhibits hypertrophy and apoptosis of podocyte in vivo and in vitro. International journal of clinical and experimental medicine. vol 8. issue 10. 2016-01-15. PMID:26770644. |
the present study aimed to examine the effect of mycophenolate mofetil (mmf), a new immunosuppressive agent, on hypertrophy and apoptosis of podocyte, and investigate the underlying mechanisms. |
2016-01-15 |
2023-08-13 |
Not clear |
| Poli Mara Spritzer, Sheila B Lecke, Fabíola Satler, Debora M Morsc. Adipose tissue dysfunction, adipokines, and low-grade chronic inflammation in polycystic ovary syndrome. Reproduction (Cambridge, England). vol 149. issue 5. 2016-01-12. PMID:25628442. |
hypertrophic adipocytes are more susceptible to inflammation, apoptosis, fibrosis, and release of free fatty acids. |
2016-01-12 |
2023-08-13 |
Not clear |
| Mathias Mericska. [MicroRNAs: what cardiologists should know about them?]. Presse medicale (Paris, France : 1983). vol 44. issue 7-8. 2016-01-10. PMID:26163829. |
mirnas regulate most cellular processes involved in the cardiovascular pathophysiology including apoptosis, proliferation and migration, left ventricle hypertrophy, cardiac fibrosis and conduction. |
2016-01-10 |
2023-08-13 |
human |