| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Viktoria Weixler, Razvan Lapusca, Gernot Grangl, Alvise Guariento, Mossab Y Saeed, Douglas B Cowan, Pedro J Del Nido, James D McCully, Ingeborg Frieh. Autogenous mitochondria transplantation for treatment of right heart failure. The Journal of thoracic and cardiovascular surgery. vol 162. issue 1. 2021-07-12. PMID:32919774. |
a key event in the progression to right ventricular hypertrophy and failure is cardiomyocyte apoptosis due to mitochondrial dysfunction. |
2021-07-12 |
2023-08-13 |
Not clear |
| M Bastin, F Andreell. The gut microbiota and diabetic cardiomyopathy in humans. Diabetes & metabolism. vol 46. issue 3. 2021-07-07. PMID:31678397. |
in patients with dt2, diabetic cardiomyopathy is a recognized cause of cardiac insufficiency secondary to chronic hyperglycaemia and myocardial lipotoxicity, which promotes cardiomyocyte hypertrophy (and, frequently, apoptosis of these cells), interstitial fibrosis and a decrease in myocardial contractile performance. |
2021-07-07 |
2023-08-13 |
Not clear |
| Maria-Madălina Bostan, Cristian Stătescu, Larisa Anghel, Ionela-Lăcrămioara Șerban, Elena Cojocaru, Radu Sască. Post-Myocardial Infarction Ventricular Remodeling Biomarkers-The Key Link between Pathophysiology and Clinic. Biomolecules. vol 10. issue 11. 2021-07-06. PMID:33238444. |
there are six main processes that promote the remodeling and each of them has specific biomarkers that can be used in predicting the evolution (myocardial necrosis, neurohormonal activation, inflammatory reaction, hypertrophy and fibrosis, apoptosis, mixed processes). |
2021-07-06 |
2023-08-13 |
Not clear |
| Syeda Thabassum Akhtar Iqbal, Pichiah Balasubramanian Tirupathi Pichiah, Sudhakaran Raja, Sankarganesh Arunachala. Paeonol Reverses Adriamycin Induced Cardiac Pathological Remodeling through Notch1 Signaling Reactivation in H9c2 Cells and Adult Zebrafish Heart. Chemical research in toxicology. vol 33. issue 2. 2021-07-02. PMID:31307187. |
adriamycin induces pathological remodeling in cardiac cells by promoting apoptosis, hypertrophy, and fibrosis. |
2021-07-02 |
2023-08-13 |
zebrafish |
| Syeda Thabassum Akhtar Iqbal, Pichiah Balasubramanian Tirupathi Pichiah, Sudhakaran Raja, Sankarganesh Arunachala. Paeonol Reverses Adriamycin Induced Cardiac Pathological Remodeling through Notch1 Signaling Reactivation in H9c2 Cells and Adult Zebrafish Heart. Chemical research in toxicology. vol 33. issue 2. 2021-07-02. PMID:31307187. |
we used paeonol, a notch1 activator, and analyzed the markers of apoptosis, hypertrophy, and fibrosis in h9c2 cells |
2021-07-02 |
2023-08-13 |
zebrafish |
| Min Liu, Zhe Qiao, Yang Zhang, Ping Zhan, Fan Y. Histone Deacetylases Take Center Stage on Regulation of Podocyte Function. Kidney diseases (Basel, Switzerland). vol 6. issue 4. 2021-07-02. PMID:32903938. |
podocytes (highly specialized and terminally differentiated epithelial cells) are integral components of the glomerular filtration barrier that are vulnerable to a variety of injuries and, as a result, they undergo a series of changes ranging from hypertrophy to detachment and apoptosis. |
2021-07-02 |
2023-08-13 |
Not clear |
| Yu Zhao, Wei-Wei Jia, San Ren, Wei Xiao, Guang-Wei Li, Li Jin, Yan Li. Difluoromethylornithine attenuates isoproterenol-induced cardiac hypertrophy by regulating apoptosis, autophagy and the mitochondria-associated membranes pathway. Experimental and therapeutic medicine. vol 22. issue 2. 2021-07-02. PMID:34194548. |
difluoromethylornithine attenuates isoproterenol-induced cardiac hypertrophy by regulating apoptosis, autophagy and the mitochondria-associated membranes pathway. |
2021-07-02 |
2023-08-13 |
rat |
| Yu Zhao, Wei-Wei Jia, San Ren, Wei Xiao, Guang-Wei Li, Li Jin, Yan Li. Difluoromethylornithine attenuates isoproterenol-induced cardiac hypertrophy by regulating apoptosis, autophagy and the mitochondria-associated membranes pathway. Experimental and therapeutic medicine. vol 22. issue 2. 2021-07-02. PMID:34194548. |
the expression of atrial natriuretic peptide (anp) mrna,heart parameters, apoptosis rate, fibrotic area and protein expressions of cleaved caspase3/9, grp75, mfn2, cypd and vdac1 were measured to confirm the development of cardiac hypertrophy, apoptosis and autophagy induced by iso. |
2021-07-02 |
2023-08-13 |
rat |
| Lin Yang, Changdong Fan, Taipengfei Shu, Shujun Wan. Punicalin alleviates TNF-α- and IL-1β-induced chondrocyte dysfunction and cartilage metabolism via mediating FOXO3 signaling axis. Journal of food biochemistry. 2021-06-30. PMID:33974280. |
punicalin treatment improved il-1β and tnf-α-induced growth inhibition and apoptosis of chondrocyte and the abnormal expansion of growth plate and hypertrophic zone. |
2021-06-30 |
2023-08-13 |
mouse |
| Fang Xie, Zhu-Song Mei, Xue Wang, Tao Zhang, Yun Zhao, Shi-Da Wang, Ling-Jia Qia. Loss of nuclear ARC contributes to the development of cardiac hypertrophy in rats. Acta physiologica (Oxford, England). vol 228. issue 2. 2021-06-25. PMID:31257698. |
cardiac hypertrophy and myocardial apoptosis are two major factors in heart failure. |
2021-06-25 |
2023-08-13 |
rat |
| Fang Xie, Zhu-Song Mei, Xue Wang, Tao Zhang, Yun Zhao, Shi-Da Wang, Ling-Jia Qia. Loss of nuclear ARC contributes to the development of cardiac hypertrophy in rats. Acta physiologica (Oxford, England). vol 228. issue 2. 2021-06-25. PMID:31257698. |
as a classical regulator of apoptosis, apoptosis repressor with caspase recruitment domain (arc) has recently also been found to have a protective effect against hypertrophy. |
2021-06-25 |
2023-08-13 |
rat |
| Jun Tang, Jianing Yang, Hua Hu, Ying Cen, Junjie Che. miR-211-5p inhibits the proliferation, migration, invasion, and induces apoptosis of human hypertrophic scar fibroblasts by regulating TGFβR2 expression. Annals of translational medicine. vol 9. issue 10. 2021-06-25. PMID:34164498. |
mir-211-5p inhibits the proliferation, migration, invasion, and induces apoptosis of human hypertrophic scar fibroblasts by regulating tgfβr2 expression. |
2021-06-25 |
2023-08-13 |
human |
| Ling Gao, Lu Wang, Yuhua Wei, Prasanna Krishnamurthy, Gregory P Walcott, Philippe Menasché, Jianyi Zhan. Exosomes secreted by hiPSC-derived cardiac cells improve recovery from myocardial infarction in swine. Science translational medicine. vol 12. issue 561. 2021-06-23. PMID:32938792. |
in vivo, measurements of left ventricular ejection fraction, wall stress, myocardial bioenergetics, cardiac hypertrophy, scar size, cell apoptosis, and angiogenesis in the infarcted region were better in the mi + cell, mi + fra, and mi + exo groups than in the mi group 4 weeks after infarction. |
2021-06-23 |
2023-08-13 |
mouse |
| Fangfang Li, Yiming Yang, Chuanyou Xue, Mengtong Tan, Lu Xu, Jianbo Gao, Luhong Xu, Jing Zong, Wenhao Qia. Zinc Finger Protein ZBTB20 protects against cardiac remodelling post-myocardial infarction via ROS-TNFα/ASK1/JNK pathway regulation. Journal of cellular and molecular medicine. vol 24. issue 22. 2021-06-21. PMID:33063955. |
then four weeks after mi, vehicle-treated mice with left ventricular (lv) remodelling underwent deterioration of cardiac function, with symptoms of hypertrophy, interstitial fibrosis, inflammation and apoptosis. |
2021-06-21 |
2023-08-13 |
mouse |
| Xuan Xiao, Yi-Zhang Liu, Zhe-Bin Cheng, Jia-Xiang Sun, Yi-Duo Shao, Shun-Lin Qu, Liang Huang, Chi Zhan. Adipokines in vascular calcification. Clinica chimica acta; international journal of clinical chemistry. vol 516. 2021-06-21. PMID:33476587. |
the chronic hypoxia in at, caused by the adipocyte hypertrophy, is able to trigger imbalanced adipokine generation, which leads to apoptosis, osteogenic differentiation of vascular smooth muscle cells (vsmcs), vascular inflammation, and abnormal deposition of calcium and phosphorus in the vessel wall. |
2021-06-21 |
2023-08-13 |
Not clear |
| Ganesh Kumar Raut, Sairam Manchineela, Moumita Chakrabarti, Chaitanya Kumar Bhukya, Raju Naini, A Venkateshwari, V D Reddy, Jolly Janette Mendonza, Y Suresh, Pratibha Nallari, Manika Pal Bhadr. Imine stilbene analog ameliorate isoproterenol-induced cardiac hypertrophy and hydrogen peroxide-induced apoptosis. Free radical biology & medicine. vol 153. 2021-06-18. PMID:32311492. |
imine stilbene analog ameliorate isoproterenol-induced cardiac hypertrophy and hydrogen peroxide-induced apoptosis. |
2021-06-18 |
2023-08-13 |
rat |
| Ganesh Kumar Raut, Sairam Manchineela, Moumita Chakrabarti, Chaitanya Kumar Bhukya, Raju Naini, A Venkateshwari, V D Reddy, Jolly Janette Mendonza, Y Suresh, Pratibha Nallari, Manika Pal Bhadr. Imine stilbene analog ameliorate isoproterenol-induced cardiac hypertrophy and hydrogen peroxide-induced apoptosis. Free radical biology & medicine. vol 153. 2021-06-18. PMID:32311492. |
the present study was aimed at designing and synthesizing a series of imine stilbene analogs and investigate its anti hypertrophic effects and regulatory mechanism in cardiac hypertrophy and apoptosis. |
2021-06-18 |
2023-08-13 |
rat |
| Fuyang Zhang, Kai Wang, Shumiao Zhang, Juan Li, Rong Fan, Xiyao Chen, Jianming Pe. Accelerated FASTK mRNA degradation induced by oxidative stress is responsible for the destroyed myocardial mitochondrial gene expression and respiratory function in alcoholic cardiomyopathy. Redox biology. vol 38. 2021-06-18. PMID:33197770. |
compared to wild type control, alcohol-related myocardial morphological (hypertrophy, fibrosis and cardiomyocyte apoptosis) and functional (reduced ejection fraction and compromised cardiomyocyte contraction) anomalies were worsened in fastk deficient mice. |
2021-06-18 |
2023-08-13 |
mouse |
| Fu Chen, Xueling Li, Jinxuan Zhao, Jin Geng, Jun Xie, Biao X. Bone marrow mesenchymal stem cell-derived exosomes attenuate cardiac hypertrophy and fibrosis in pressure overload induced remodeling. In vitro cellular & developmental biology. Animal. vol 56. issue 7. 2021-06-10. PMID:32748023. |
mscs-derived exosomes significantly protected myocardium against cardiac hypertrophy, attenuated myocardial apoptosis, and fibrosis and preserved heart function when pressure overload. |
2021-06-10 |
2023-08-13 |
mouse |
| Lili Zhang, Zhige Wen, Lin Han, Yujiao Zheng, Yu Wei, Xinmiao Wang, Qing Wang, Xinyi Fang, Linhua Zhao, Xiaolin Ton. Research Progress on the Pathological Mechanisms of Podocytes in Diabetic Nephropathy. Journal of diabetes research. vol 2020. 2021-06-09. PMID:32695831. |
a series of morphological changes after podocyte injury in dn mainly include podocyte hypertrophy, podocyte epithelial-mesenchymal transdifferentiation, podocyte detachment, and podocyte apoptosis; functional changes mainly involve podocyte autophagy. |
2021-06-09 |
2023-08-13 |
Not clear |