| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Maha Moussa, Marina Pozzolini, Sara Ferrando, Asma Mannai, Eleonora Tassara, Marco Giovine, Khaled Sai. Insight on thermal stress response of demosponge Chondrosia reniformis (Nardo, 1847). The Science of the total environment. 2023-12-30. PMID:38159772. |
however, exposure to 30 °c at both periods of time resulted in indication of hsp, antioxidant enzymes, the gene involved in the apoptosis process (bcl-2: b-cell lymphoma 2), the gene involved in inflammation (tnf: tumor necrosis factor), as well as the aquaporin gene, involved in h |
2023-12-30 |
2024-01-05 |
Not clear |
| Hema Priya Manivannan, Vishnu Priya Veeraraghavan, Arul Prakash Franci. Identification of molecular targets of Trigonelline for treating breast cancer through network pharmacology and bioinformatics-based prediction. Molecular diversity. 2023-12-25. PMID:38145425. |
at the same time, parp1, ddit3, bax, and tnf were associated with the apoptosis pathway according to kegg pathway enrichment analyses. |
2023-12-25 |
2023-12-27 |
Not clear |
| Sandeep Paudel, Neha Mishra, Rajesh Agarwa. Phytochemicals as Immunomodulatory Molecules in Cancer Therapeutics. Pharmaceuticals (Basel, Switzerland). vol 16. issue 12. 2023-12-23. PMID:38139779. |
phytochemicals and their products have demonstrated immune regulation, such as macrophage migration, nitric oxide synthase inhibition, lymphocyte, t-cell, and cytokine stimulation, natural killer cell augmentation, and nfκb, tnf, and apoptosis regulation. |
2023-12-23 |
2023-12-25 |
Not clear |
| Rui Chen, Chao Song, Junjie Qiu, Qifan Su, Xiaoqiang Wang, Guanghui Deng, Kang Cheng, Xiaoyu Chen, Wei Xiang, Tao Liu, Xiaojun Chen, Jiaqi W. Exploring the potential mechanism of Taohong Siwu decoction in the treatment of avascular necrosis of the femoral head based on network pharmacology and molecular docking. Medicine. vol 102. issue 50. 2023-12-20. PMID:38115279. |
the kyoto encyclopedia of genes and genomes signaling pathway mainly involves tnf signaling pathway, il-17 signaling pathway, and the recactome pathway mainly involves signaling by interleukins, apoptosis, and intrinsic pathway for apoptosis. |
2023-12-20 |
2023-12-23 |
Not clear |
| Aoife Costigan, Emilie Hollville, Seamus J Marti. Discriminating Between Apoptosis, Necrosis, Necroptosis, and Ferroptosis by Microscopy and Flow Cytometry. Current protocols. vol 3. issue 12. 2023-12-19. PMID:38112058. |
numerous physiological as well as pathological stimuli trigger apoptosis, such as engagement of plasma-membrane-associated fas, trail, or tnf receptors, growth factor deprivation, hypoxia, radiation, and exposure to diverse cytotoxic drugs. |
2023-12-19 |
2023-12-21 |
Not clear |
| Juan Pablo Robles, Magdalena Zamora, Jose F Garcia-Rodrigo, Alma Lorena Perez, Thomas Bertsch, Gonzalo Martinez de la Escalera, Jakob Triebel, Carmen Clap. Vasoinhibin apoptotic, inflammatory, and fibrinolytic actions are in a motif different from its antiangiogenic HGR motif. Endocrinology. 2023-12-06. PMID:38057149. |
instead, the incubation of human umbilical vein endothelial cells with oligopeptides containing the sequence hnlssem, corresponding to residues 30 to 36 of vasoinhibin, induced apoptosis, nuclear translocation of nf-κb, expression of genes encoding leukocyte adhesion molecules (vcam1 and icam1) and proinflammatory cytokines (il1b, il6, tnf), and adhesion of peripheral blood leukocytes. |
2023-12-06 |
2023-12-10 |
mouse |
| Ying Wang, Xueying Chen, Yan Wang, Hong Zhong, Liqin Liu, Yang Y. Network pharmacology integrated with molecular docking technology to reveal the potential mechanism of Shuganfang against drug-induced liver injury. Medicine. vol 102. issue 48. 2023-12-05. PMID:38050247. |
kegg analysis revealed that the treatment of dili with sgf mainly acted through apoptosis, the pi3k-akt signaling pathway, and the tumor necrosis factor (tnf) signaling pathway. |
2023-12-05 |
2023-12-10 |
Not clear |
| Gang Liu, Bowen Deng, Luyao Huo, Shengyuan Jiang, Xiao Fan, Yanjun Mo, Jingpei Ren, Yi Zhao, Lin Xu, Xiaohong M. Temporal Profiling and Validation of Oxidative Stress-Related Genes in Spinal Cord Injury. Brain research bulletin. 2023-12-02. PMID:38042503. |
notably, kegg enrichment analysis revealed a pronounced enrichment of pivotal pathways, namely mapk, foxo, apoptosis, nf-κb, tnf, hif-1, and chemokine across distinct phases of sci. |
2023-12-02 |
2023-12-10 |
rat |
| Rebekka Lambrecht, M Eugenia Delgado, Vincent Gloe, Karina Schuetz, Anna Pia Plazzo, Barbara Franke, Truong San Phan, Jennifer Fleming, Olga Mayans, Thomas Brunne. Liver receptor homolog-1 (NR5A2) orchestrates hepatic inflammation and TNF-induced cell death. Cell reports. vol 42. issue 12. 2023-12-01. PMID:38039134. |
hepatocyte-specific deletion of lrh-1 causes mild steatosis and inflammation but unexpectedly shields female mice from tumor necrosis factor (tnf)-induced hepatocyte apoptosis and associated hepatitis. |
2023-12-01 |
2023-12-10 |
mouse |
| Allen Caobi, Jesenia Bonilla, Mario Gomez, Mickensone Andre, Adriana Yndart, Francisco A Fernandez-Lima, Madhavan P Nair, Andrea D Raymon. HIV-1 and opiates modulate miRNA profiles in extracellular vesicles. Frontiers in immunology. vol 14. 2023-12-01. PMID:38022533. |
overall, hiv-1 and morphine induced differential mirna expression in pbmc-derived exosomes, potentially identifying mechanisms of action or novel therapeutic targets involved in opiate use disorder, hiv neuropathology, tnf signaling pathway, nf-κb signaling pathway, autophagy, and apoptosis in context of hiv infection. |
2023-12-01 |
2023-12-07 |
Not clear |
| Allen Caobi, Jesenia Bonilla, Mario Gomez, Mickensone Andre, Adriana Yndart, Francisco A Fernandez-Lima, Madhavan P Nair, Andrea D Raymon. HIV-1 and opiates modulate miRNA profiles in extracellular vesicles. Frontiers in immunology. vol 14. 2023-12-01. PMID:38022533. |
overall, hiv-1 and morphine induced differential mirna expression in pbmc-derived exosomes, potentially identifying mechanisms of action or novel therapeutic targets involved in opiate use disorder, hiv neuropathology, tnf signaling pathway, nf-κb signaling pathway, autophagy, and apoptosis in context of hiv infection. |
2023-11-29 |
2023-12-07 |
Not clear |
| Yu Wang, Hidekatsu Ih. The Novel Link between Gene Expression Profiles of Adult T-Cell Leukemia/Lymphoma Patients' Peripheral Blood Lymphocytes and Ferroptosis Susceptibility. Genes. vol 14. issue 11. 2023-11-25. PMID:38002949. |
autophagy-related degs are linked to autophagy, apoptosis, nod-like receptor signaling, tnf signaling, and the insulin resistance pathway. |
2023-11-25 |
2023-11-28 |
Not clear |
| Yi Wen, Xiaohan Lu, Jamie R Privratsky, Jiafa Ren, Saba Ali, Bo Yang, Nathan P Rudemiller, Jiandong Zhang, Sergei A Nedospasov, Steven D Crowle. TNF-α From the Proximal Nephron Exacerbates Aristolochic Acid Nephropathy. Kidney360. 2023-11-21. PMID:37986166. |
although tumor necrosis factor-α (tnf) regulates cell apoptosis and inflammatory responses, the effects of tubular tnf in the progression of aan require elucidation. |
2023-11-21 |
2023-11-29 |
Not clear |
| Hoa Dinh, Zsuzsanna Z A Kovács, Merse Kis, Klaudia Kupecz, Anita Sejben, Gergő Szűcs, Fanni Márványkövi, Andrea Siska, Marah Freiwan, Szonja Polett Pósa, Zsolt Galla, Katalin Eszter Ibos, Éva Bodnár, Gülsüm Yilmaz Lauber, Ana Isabel Antunes Goncalves, Eylem Acar, András Kriston, Ferenc Kovács, Péter Horváth, Zsolt Bozsó, Gábor Tóth, Imre Földesi, Péter Monostori, Gábor Cserni, Bruno K Podesser, Andrea Lehoczki, Peter Pokreisz, Attila Kiss, László Dux, Krisztina Csabafi, Márta Sárköz. Role of the kisspeptin-KISS1R axis in the pathogenesis of chronic kidney disease and uremic cardiomyopathy. GeroScience. 2023-11-21. PMID:37987885. |
in contrast, the higher kp-13 dose correlated with reduced posterior and anterior wall thickness, coupled with diminished cardiomyocyte cross-sectional areas and concurrent elevation of inflammatory (il6, tnf), fibrosis (col1), and apoptosis markers (bax/bcl2) relative to the ckd group. |
2023-11-21 |
2023-11-29 |
rat |
| Laura Boswell, Antonio J Amor, Enrique Montagud-Marrahi, Gregori Casals, Daniela Díaz-Catalan, Elisenda Banon-Maneus, María José Ramírez-Bajo, Natalia Hierro, Fritz Diekmann, Mireia Musquera, Tonet Serés-Noriega, Enric Esmatjes, Joana Ferrer-Fàbrega, Pedro Ventura-Aguiar, Felicia A Hanz. Midnight Cortisol is Associated with Changes in Systolic Blood Pressure and Diabetic Neuropathy in Subjects with Type 1 Diabetes Undergoing Simultaneous Kidney-Pancreas Transplantation. Diabetes therapy : research, treatment and education of diabetes and related disorders. 2023-11-02. PMID:37917327. |
lower circulating levels of the cytokine soluble tumor necrosis factor (tnf)-like weak inducer of apoptosis (stweak) have been found in t1d and eskd and associated with cardiovascular (cv) events in the latter. |
2023-11-02 |
2023-11-08 |
human |
| Vishal Devarkonda, Shravya Balmuri, Maria Antonia Costa Cruz Akabane, Hugo Akaban. Adalimumab-associated Philadelphia chromosome positive acute lymphoblastic leukaemia in a patient with Crohn's disease. BMJ case reports. vol 16. issue 10. 2023-10-25. PMID:37879713. |
however, these inhibitors can potentially increase the risk of secondary blood malignancies due to tnf alpha's role in various cellular processes such as angiogenesis, cell cycle proliferation, apoptosis and differentiation. |
2023-10-25 |
2023-11-08 |
human |
| Xiaobo Yan, Weibin Huang, Xiangxiang Suo, Simiao Pan, Tao Li, Hao Liu, Beiping Tan, Shuang Zhang, Yuanzhi Yang, Xiaohui Don. Integrated analysis of microbiome and host transcriptome reveals the damage/protective mechanism of corn oil and olive oil on the gut health of grouper (♀ Epinephelus fuscoguttatus × ♂ E. lanceolatu). International journal of biological macromolecules. 2023-10-21. PMID:37865354. |
transcriptome sequencing further revealed co could activated complement and coagulation cascades, staphylococcus aureus infection, systemic lupus erythematosus, and tuberculosis pathways; conversely, oo activated b-cell signaling receptors, promoted b-cell proliferation and apoptosis, and thus activated b-cell signaling pathways to enhance immunity, whereas oo can regulate il17 signaling pathway and tnf signaling pathway to inhibit nf-κb signaling pathway to reduce pro-inflammatory response. |
2023-10-21 |
2023-11-08 |
Not clear |
| Xiqoqiang Wang, Hongtao Li, Longhai Long, Chao Song, Rui Chen, Hongyu Pan, Junjie Qiu, Bing Liu, Zongchao Li. Mechanism of Liuwei Dihuang Pills in treating osteoporosis based on network pharmacology. Medicine. vol 102. issue 42. 2023-10-20. PMID:37861542. |
specifically, it mainly involves tnf, il17, and hif-1 signaling pathways and helps regulate biological processes such as angiogenesis, apoptosis, hypoxia, and gene expression. |
2023-10-20 |
2023-11-08 |
rat |
| Madhana Vigneshwari Gopal Samy, Sasidharan Peruma. Systems pharmacology and multi-scale mechanism of Enicostema axillare bioactives in treating Alzheimer disease. Inflammopharmacology. 2023-10-16. PMID:37845599. |
in brief, we bring to light the three active compounds of ea and seven potential molecular targets of ad, which are mainly implicated in four signaling pathways, i.e., mapk, apoptosis, neurodegeneration, and the tnf pathway. |
2023-10-16 |
2023-11-08 |
Not clear |
| Tanmoy Mondal, Himanshu Gaur, Brice E N Wamba, Abby Grace Michalak, Camryn Stout, Matthew R Watson, Sophia L Aleixo, Arjun Singh, Salvatore Condello, Roland Faller, Gary Scott Leiserowitz, Sanchita Bhatnagar, Jogender Tushir-Sing. Characterizing the regulatory Fas (CD95) epitope critical for agonist antibody targeting and CAR-T bystander function in ovarian cancer. Cell death and differentiation. 2023-10-14. PMID:37838774. |
receptor clustering is the most critical step to activate extrinsic apoptosis by death receptors belonging to the tnf superfamily. |
2023-10-14 |
2023-11-08 |
Not clear |