| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jungang Huang, Zexiong Li, Weipeng Huang, Junbing He, Junmeng Zheng, Shaoru Jiang, Jun Lin, Mingwei X. Ablation of CCDC8 provides cardioprotection against cardiomyocyte apoptosis via TNF signaling pathway in myocardial ischemia reperfusion injury. Life sciences. 2024-10-18. PMID:39424266. |
ablation of ccdc8 provides cardioprotection against cardiomyocyte apoptosis via tnf signaling pathway in myocardial ischemia reperfusion injury. |
2024-10-18 |
2024-10-21 |
Not clear |
| Gareth Hazell, Eve McCallion, Nina Ahlskog, Emma R Sutton, Magnus Okoh, Emad I H Shaqoura, Joseph M Hoolachan, Taylor Scaife, Sara Iqbal, Amarjit Bhomra, Anna J Kordala, Frederique Scamps, Cedric Raoul, Matthew J A Wood, Melissa Bowerma. Exercise, disease state and sex influence the beneficial effects of Fn14-depletion on survival and muscle pathology in the SOD1 Skeletal muscle. vol 14. issue 1. 2024-10-13. PMID:39396990. |
we have previously reported that tumour necrosis factor (tnf)-like weak inducer of apoptosis (tweak) and fibroblast growth factor inducible 14 (fn14) are significantly upregulated in skeletal muscle of the sod1 |
2024-10-13 |
2024-10-16 |
Not clear |
| Ming-Tse Sung, Hsuan-En Huang, Ya-Chuan Chang, Chia-Ying Yu, Hao-Lun Luo, Wen-Wei Sun. Anticancer potential of isoalantolactone in testicular cancer: an analysis of cytotoxicity, apoptosis, and signaling pathways. Aging. vol 16. 2024-10-09. PMID:39382942. |
human apoptosis array analysis demonstrated iatl's influence on hif-1α and tnf r1 expression, implicating its role in cancer cell growth and death regulation. |
2024-10-09 |
2024-10-11 |
human |
| Kai Liu, Jing An, Jing Zhang, Jihu Zhao, Peng Sun, Zhaohui H. Network pharmacology combined with experimental validation show that apigenin as the active ingredient of Campsis grandiflora flower against Parkinson's disease by inhibiting the PI3K/AKT/NF-κB pathway. PloS one. vol 19. issue 10. 2024-10-09. PMID:39383141. |
the primary routes implicated were identified as pi3k/akt, apoptosis, tnf, and nf-κb pathways. |
2024-10-09 |
2024-10-12 |
Not clear |
| Annie Wai Yeeng Chai, Yee Hua Tan, Shiyin Ooi, Pei San Yee, Shi Mun Yee, Howard Lightfoot, Syd Barthorpe, Mathew J Garnett, Sok Ching Cheon. High TNF and NF-ĸB pathway dependency are associated with AZD5582 sensitivity in OSCC via CASP8-dependent apoptosis. Cancer research communications. 2024-10-03. PMID:39360810. |
high tnf and nf-ĸb pathway dependency are associated with azd5582 sensitivity in oscc via casp8-dependent apoptosis. |
2024-10-03 |
2024-10-05 |
Not clear |
| Kelly Xue Jing Jong, Elsa Haniffah Mejia Mohamed, Saiful Effendi Syafruddin, Farid Nazer Faruqu, Kumutha Malar Vellasamy, Kamariah Ibrahim, Zaridatul Aini Ibrahi. IL-8 and PI3K pathway influence the susceptibility of TRAIL-sensitive colorectal cancer cells to TRAIL-induced cell death. Molecular biology reports. vol 51. issue 1. 2024-09-13. PMID:39269555. |
tumour necrosis factor (tnf)-related apoptosis-inducing ligand (trail) is an apoptosis inducer that exhibits an ideal therapeutic safety profile with less adverse effects than conventional chemotherapy. |
2024-09-13 |
2024-09-16 |
Not clear |
| Zebing Ma, Peng Zeng, Haibo Feng, Lili N. Network pharmacology and molecular docking to explore the treatment potential and molecular mechanism of Si-Miao decoction against gouty arthritis. Medicine. vol 103. issue 22. 2024-09-11. PMID:39259129. |
go and kegg analyses showed that the mechanism of anti-ga in si-miao decoction may proceed by regulating biological processes such as inflammatory factor levels, cell proliferation, apoptosis, and lipid and glucose metabolism, and modulating the nod-like receptor signaling pathway, il-17 signaling pathway, tnf signaling pathway, nf-kappa b signaling pathway, and toll-like receptor signaling pathway. |
2024-09-11 |
2024-09-13 |
Not clear |
| Emily J Lelliott, Jonathan Naddaf, Katherine Ganio, Jessica Michie, Shelly Wang, Lin Liu, Natasha Silke, Antonio Ahn, Kelly M Ramsbottom, Amelia J Brennan, Andrew J Freeman, Shom Goel, Stephin J Vervoort, Conor J Kearney, Paul A Beavis, Christopher A McDevitt, John Silke, Jane Oliar. Intracellular zinc protects tumours from T cell-mediated cytotoxicity. Cell death and differentiation. 2024-09-11. PMID:39261596. |
moreover, we demonstrated that modulation of cellular zinc, achieved by supplementation or chelation, significantly altered tumour cell susceptibility to tnf by regulating the levels of inhibitor of apoptosis proteins. |
2024-09-11 |
2024-09-14 |
Not clear |
| Fatmawati Lambuk, Nor Asyikin Nordin, Ali Mussa, Lidawani Lambuk, Suhana Ahmad, Rosline Hassan, Ramlah Kadir, Rohimah Mohamud, Nurul Khaiza Yahy. Towards understanding the role of nanomedicine in targeting TNFR2 in rheumatoid arthritis. Immunology. 2024-08-27. PMID:39191474. |
it promotes inflammatory, apoptosis and necroptosis via tnf receptor-1 (tnfr1) but elicit anti-inflammatory effects via tnfr2. |
2024-08-27 |
2024-08-30 |
Not clear |
| Muhammad S Alam, Matthias M Gaida, Hagen R Witzel, Shizuka Otsuka, Aamna Abbasi, Theresa Guerin, Abdalla Abdelmaksoud, Nathan Wong, Margaret C Cam, Serguei Kozlov, Jonathan D Ashwel. TNFR1 signaling promotes pancreatic tumor growth by limiting dendritic cell number and function. Cell reports. Medicine. 2024-08-23. PMID:39178856. |
this may reflect a direct effect on dcs, because tnf induced tnfr1-dependent apoptosis of bone-marrow-derived dcs. |
2024-08-23 |
2024-08-27 |
Not clear |
| Mayra Fernanda Martínez-López, Cátia Rebelo de Almeida, Márcia Fontes, Raquel Valente Mendes, Stefan H E Kaufmann, Rita Fio. Macrophages directly kill bladder cancer cells through TNF signaling as an early response to BCG therapy. Disease models & mechanisms. vol 17. issue 8. 2024-08-08. PMID:39114912. |
macrophages directly induced apoptosis of human cancer cells through zebrafish tnf signaling. |
2024-08-08 |
2024-08-10 |
human |
| Hanliang Zhu, Yiwen Chen, Yuantang Zhong, Xiangwei Xie, Xiangjian Zeng, Wangdong Den. Knockdown of long non-coding RNA SBF2-AS1 inhibits calcium oxalate-induced HK-2 cell injury by regulating the miR-302e/NLRP3 pathway. Urolithiasis. vol 52. issue 1. 2024-08-06. PMID:39105900. |
proliferation and apoptosis rates, as well as levels of malondialdehyde (mda), lactate dehydrogenase (ldh), superoxide dismutase (sod), tumor necrosis factor (tnf)-α, interleukin (il)-1β, and il-6 were measured. |
2024-08-06 |
2024-08-08 |
human |
| Gabriella de Oliveira, Lucas de Andrade Rodrigues, André Acácio Souza da Silva, Lays Cristina Gouvea, Renata Cristina Lima Silva, Estela Sasso-Cerri, Paulo Sérgio Cerr. Reduction of osteoclast formation and survival following suppression of cytokines by diacerein in periodontitis. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 177. 2024-07-16. PMID:39013222. |
diacerein inhibits osteoclastogenesis by decreasing tnf and il1b mrna levels, resulting in decreased rankl/opg ratio, and induces apoptosis in osteoclasts of alveolar process of rat molars with periodontitis. |
2024-07-16 |
2024-07-19 |
rat |
| Valentina R Minciacchi, Christina Karantanou, Jimena Bravo, Raquel S Pereira, Costanza Zanetti, Theresa Krack, Rahul Kumar, Katrin Bankov, Sylvia Hartmann, Brian Jp Huntly, Eshwar Meduri, Wolfram Ruf, Daniela S Kraus. Differential inflammatory conditioning of the bone marrow by acute myeloid leukemia and its impact on progression. Blood advances. 2024-07-12. PMID:38996202. |
using annexin a5 (anxa 5), a calcium-binding protein known for apoptosis, which we discovered to be differentially expressed in the bone marrow microenvironment (bmm) of mice with acute myeloid (aml) versus chronic myeloid leukemia, as a model system, we unravel here a circuit in which aml-derived tumor necrosis factor (tnf)α dose-dependently reduces anxa5 in the bmm. |
2024-07-12 |
2024-07-15 |
mouse |
| Dengyong Zheng, Xinglin Ruan, Qiang Wu, Yuliang Qiu, Shiwei Rua. Yishen Jiangzhuo decoction attenuates cisplatin‑induced acute kidney injury by inhibiting inflammation, oxidative stress and apoptosis through the TNF signal pathway. Experimental and therapeutic medicine. vol 28. issue 2. 2024-07-10. PMID:38979022. |
yishen jiangzhuo decoction attenuates cisplatin‑induced acute kidney injury by inhibiting inflammation, oxidative stress and apoptosis through the tnf signal pathway. |
2024-07-10 |
2024-07-12 |
mouse |
| Dengyong Zheng, Xinglin Ruan, Qiang Wu, Yuliang Qiu, Shiwei Rua. Yishen Jiangzhuo decoction attenuates cisplatin‑induced acute kidney injury by inhibiting inflammation, oxidative stress and apoptosis through the TNF signal pathway. Experimental and therapeutic medicine. vol 28. issue 2. 2024-07-10. PMID:38979022. |
the results of the transcriptomic and enrichment analyses showed that the mechanisms of ysjzd may be associated with inflammation, oxidation, apoptosis and the tnf signal pathway. |
2024-07-10 |
2024-07-12 |
mouse |
| Wenyu Wu, Wanning Lan, Xin Jiao, Axue Shao, Peng Wu, Kai Wang, Shaofeng Zha. Mechanisms underlying the therapeutic effects of Gang Huo Qing wen granules in the treatment of influenza based on network pharmacology, molecular docking and molecular dynamics. Scientific reports. vol 14. issue 1. 2024-07-09. PMID:38982082. |
ghqwg's effects are mediated via genes involved in inflammation, apoptosis, and oxidative stress, as well as the tnf and il-17 signaling pathways, according to go and kegg pathway enrichment analysis. |
2024-07-09 |
2024-07-12 |
Not clear |
| Qiumin Deng, Luxuan Chen, Gui Zhang, Langxia Liu, Shi-Ming Luo, Xuejuan Ga. TRIAL-based combination therapies in cancers. International immunopharmacology. vol 138. 2024-07-06. PMID:38971105. |
tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail) shows promising therapeutic potential in cancer treatment as it is able to trigger extrinsic apoptotic pathways by binding to the cognate death receptor, causing broad-spectrum apoptosis in cancer cells with negligible toxicity to normal cells. |
2024-07-06 |
2024-07-12 |
Not clear |
| Mengqi Zheng, Yunjiao Zhai, Yanbo Yu, Jing Shen, Shuzheng Chu, Enrico Focaccia, Wenyu Tian, Sui Wang, Xuesong Liu, Xi Yuan, Yue Wang, Lixiang Li, Bingcheng Feng, Zhen Li, Xiaohuan Guo, Ju Qiu, Cuijuan Zhang, Jiajie Hou, Yiyuan Sun, Xiaoyun Yang, Xiuli Zuo, Mathias Heikenwalder, Yanqing Li, Detian Yuan, Shiyang L. TNF compromises intestinal bile-acid tolerance dictating colitis progression and limited infliximab response. Cell metabolism. 2024-07-06. PMID:38971153. |
mechanistically, excessive tumor necrosis factor (tnf) produced at the onset of colitis interferes with bile-acid detoxification through the receptor-interacting serine/threonine-protein kinase 1/extracellular signal-regulated kinase pathway in intestinal epithelial cells, leading to bile acid overload in the endoplasmic reticulum and consequent apoptosis. |
2024-07-06 |
2024-07-12 |
Not clear |
| Dapeng Zhao, Jian Song, Chongyao J. Endoplasmic reticulum stress regulates apoptosis and chemotherapeutic via enhancing TNFRSF10B recycling to the cell membrane in triple-negative breast cancer. Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico. 2024-07-05. PMID:38967737. |
the expression and cell surface levels of tnf receptor superfamily member 10b (tnfrsf10b) are associated with apoptosis and chemotherapy. |
2024-07-05 |
2024-07-11 |
Not clear |