| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R Net. Modulation with cytokines of radiation injury: suggested mechanisms of action. Environmental health perspectives. vol 105 Suppl 6. 1998-04-09. PMID:9467064. |
the radioprotective effects of cytokines can be based on induction of cycling of primitive progenitor cells (il-1, scf), prevention of apoptosis (scf), and induction of scavenging proteins and enzymes (il-1, tnf) that reduce oxidative damage. |
1998-04-09 |
2023-08-12 |
mouse |
| S Andjelic, H C Lio. Antigen receptor-induced B lymphocyte apoptosis mediated via a protease of the caspase family. European journal of immunology. vol 28. issue 2. 1998-03-31. PMID:9521067. |
it is well established that the caspases are essential for the apoptosis mediated by fas (cd95) and tnf receptor p55, molecules that contain the "death domain" in the cytoplasmic tail. |
1998-03-31 |
2023-08-12 |
Not clear |
| D Guy-Grand, J P DiSanto, P Henchoz, M Malassis-Séris, P Vassall. Small bowel enteropathy: role of intraepithelial lymphocytes and of cytokines (IL-12, IFN-gamma, TNF) in the induction of epithelial cell death and renewal. European journal of immunology. vol 28. issue 2. 1998-03-31. PMID:9521083. |
on the other hand, injection of tnf induces fulminant apoptosis of villus epithelial cells, starting at the top of the villi; however tnf is not required for il-12-induced enteropathy, which is unmodified in mutant mice lacking tnf. |
1998-03-31 |
2023-08-12 |
mouse |
| N J Donato, M Pere. Tumor necrosis factor-induced apoptosis stimulates p53 accumulation and p21WAF1 proteolysis in ME-180 cells. The Journal of biological chemistry. vol 273. issue 9. 1998-03-25. PMID:9478957. |
tumor necrosis factor (tnf)-mediated apoptotic signaling has been characterized by activation of specific protease or protein kinase cascades that regulate the onset of apoptosis. |
1998-03-25 |
2023-08-12 |
Not clear |
| N J Donato, M Pere. Tumor necrosis factor-induced apoptosis stimulates p53 accumulation and p21WAF1 proteolysis in ME-180 cells. The Journal of biological chemistry. vol 273. issue 9. 1998-03-25. PMID:9478957. |
to determine the role of genotoxic stress in tnf-mediated apoptosis, we examined cellular accumulation of p53 in tnf-treated me-180 cells selected for apoptotic sensitivity (me-180s) or resistance (me-180r) to tnf. |
1998-03-25 |
2023-08-12 |
Not clear |
| A Algeciras, D H Dockrell, D H Lynch, C V Pay. CD4 regulates susceptibility to Fas ligand- and tumor necrosis factor-mediated apoptosis. The Journal of experimental medicine. vol 187. issue 5. 1998-03-24. PMID:9480981. |
immediately after cd4 cross-linking, cd4+ t cells are rendered susceptible to apoptosis mediated by tnf or fasl. |
1998-03-24 |
2023-08-12 |
human |
| A Algeciras, D H Dockrell, D H Lynch, C V Pay. CD4 regulates susceptibility to Fas ligand- and tumor necrosis factor-mediated apoptosis. The Journal of experimental medicine. vol 187. issue 5. 1998-03-24. PMID:9480981. |
the cd4-dependent induction of susceptibility to apoptosis that is mediated by tnf or fasl is protein synthesis independent but phosphorylation dependent. |
1998-03-24 |
2023-08-12 |
human |
| A Srinivasan, F Li, A Wong, L Kodandapani, R Smidt, J F Krebs, L C Fritz, J C Wu, K J Tomasell. Bcl-xL functions downstream of caspase-8 to inhibit Fas- and tumor necrosis factor receptor 1-induced apoptosis of MCF7 breast carcinoma cells. The Journal of biological chemistry. vol 273. issue 8. 1998-03-19. PMID:9468507. |
in some cells, bcl-xl overexpression can inhibit anti-fas- and tumor necrosis factor (tnf)-alpha-induced apoptosis. |
1998-03-19 |
2023-08-12 |
human |
| Y L Wu, X R Jiang, D M Lillington, P D Allen, A C Newland, S M Kelse. 1,25-Dihydroxyvitamin D3 protects human leukemic cells from tumor necrosis factor-induced apoptosis via inactivation of cytosolic phospholipase A2. Cancer research. vol 58. issue 4. 1998-03-19. PMID:9485014. |
prior incubation of cells with 1,25(oh)2d3 significantly inhibited (a) tnf-induced [3h]arachidonic acid release and apoptosis, (b) tnf-induced translocation of cpla2 to the membrane, and (c) the up-regulation of cpla2 mrna with tnf. |
1998-03-19 |
2023-08-12 |
human |
| I Jeremias, I Herr, T Boehler, K M Debati. TRAIL/Apo-2-ligand-induced apoptosis in human T cells. European journal of immunology. vol 28. issue 1. 1998-03-19. PMID:9485194. |
members of the tumor necrosis factor (tnf) family such as cd95 (apo-1/fas) ligand (l) trigger apoptosis in lymphoid cells. |
1998-03-19 |
2023-08-12 |
human |
| Y Li, J Kang, M S Horwit. Interaction of an adenovirus E3 14.7-kilodalton protein with a novel tumor necrosis factor alpha-inducible cellular protein containing leucine zipper domains. Molecular and cellular biology. vol 18. issue 3. 1998-03-19. PMID:9488477. |
fip-2 by itself does not cause cell death; however, it can reverse the protective effect of e3-14.7k on cell killing induced by overexpression of the intracellular domain of the 55-kda tnf receptor or by rip, a death protein involved in the tnf-alpha and fas apoptosis pathways. |
1998-03-19 |
2023-08-12 |
human |
| J Langstein, J Michel, J Fritsche, M Kreutz, R Andreesen, H Schwar. CD137 (ILA/4-1BB), a member of the TNF receptor family, induces monocyte activation via bidirectional signaling. Journal of immunology (Baltimore, Md. : 1950). vol 160. issue 5. 1998-03-18. PMID:9498794. |
cd137 (ila/4-1bb), a member of the tnf receptor family, was shown previously to inhibit proliferation and to induce apoptosis in t lymphocytes. |
1998-03-18 |
2023-08-12 |
Not clear |
| B Combadière, C Reis e Sousa, R N Germain, M J Lenard. Selective induction of apoptosis in mature T lymphocytes by variant T cell receptor ligands. The Journal of experimental medicine. vol 187. issue 3. 1998-03-13. PMID:9449715. |
here we describe altered ligands for mature mouse cd4(+) t helper 1 cells that lead to t cell apoptosis by the selective expression of fas ligand (fasl) and tumor necrosis factor (tnf) without concomitant il-2, il-3, or interferon gamma production. |
1998-03-13 |
2023-08-12 |
mouse |
| R Kettritz, M L Gaido, H Haller, F C Luft, C J Jennette, R J Fal. Interleukin-8 delays spontaneous and tumor necrosis factor-alpha-mediated apoptosis of human neutrophils. Kidney international. vol 53. issue 1. 1998-03-05. PMID:9453003. |
interleukin-8 also inhibited tnf alpha-mediated pmn apoptosis. |
1998-03-05 |
2023-08-12 |
human |
| R B Ray, K Meyer, R Steele, A Shrivastava, B B Aggarwal, R Ra. Inhibition of tumor necrosis factor (TNF-alpha)-mediated apoptosis by hepatitis C virus core protein. The Journal of biological chemistry. vol 273. issue 4. 1998-03-03. PMID:9442069. |
since tumor necrosis factor (tnf) plays an important role in controlling viral infection, in this study the effect of the core protein was investigated on the tnf-alpha induced apoptosis of human breast carcinoma cells (mcf7). |
1998-03-03 |
2023-08-12 |
human |
| S P Srivastava, K U Kumar, R J Kaufma. Phosphorylation of eukaryotic translation initiation factor 2 mediates apoptosis in response to activation of the double-stranded RNA-dependent protein kinase. The Journal of biological chemistry. vol 273. issue 4. 1998-03-03. PMID:9442091. |
expression of a trans-dominant negative, catalytically inactive mutant pkr protected nih3t3 cells from apoptosis in response to either treatment with tumor necrosis factor alpha (tnf alpha), serum deprivation. |
1998-03-03 |
2023-08-12 |
Not clear |
| S P Srivastava, K U Kumar, R J Kaufma. Phosphorylation of eukaryotic translation initiation factor 2 mediates apoptosis in response to activation of the double-stranded RNA-dependent protein kinase. The Journal of biological chemistry. vol 273. issue 4. 1998-03-03. PMID:9442091. |
tnf alpha-induced apoptosis correlated with increased phosphorylation of the alpha subunit of eukaryotic translation initiation factor 2 (eif-2 alpha), the primary physiological substrate of the pkr. |
1998-03-03 |
2023-08-12 |
Not clear |
| S P Srivastava, K U Kumar, R J Kaufma. Phosphorylation of eukaryotic translation initiation factor 2 mediates apoptosis in response to activation of the double-stranded RNA-dependent protein kinase. The Journal of biological chemistry. vol 273. issue 4. 1998-03-03. PMID:9442091. |
furthermore, forced expression of a nonphosphorylatable s51a mutant eif-2 alpha partially protected cells from tnf alpha-induced apoptosis, and expression of a s51d mutant eif-2 alpha, a mutant that mimics phosphorylated eif-2 alpha, was sufficient to induce apoptosis. |
1998-03-03 |
2023-08-12 |
Not clear |
| S A Marsters, J P Sheridan, R M Pitti, A Huang, M Skubatch, D Baldwin, J Yuan, A Gurney, A D Goddard, P Godowski, A Ashkenaz. A novel receptor for Apo2L/TRAIL contains a truncated death domain. Current biology : CB. vol 7. issue 12. 1998-02-19. PMID:9382840. |
apo2 ligand (apo2l [1], also called trail for tumor necrosis factor (tnf)-related apoptosis-inducing ligand [2]) belongs to the tnf family and activates apoptosis in tumor cells. |
1998-02-19 |
2023-08-12 |
human |
| J Klefstrom, E Arighi, T Littlewood, M Jäättelä, E Saksela, G I Evan, K Alital. Induction of TNF-sensitive cellular phenotype by c-Myc involves p53 and impaired NF-kappaB activation. The EMBO journal. vol 16. issue 24. 1998-02-19. PMID:9405367. |
tnf, with c-myc, induced apoptosis in mouse primary fibroblasts but only weakly in p53-deficient primary fibroblasts. |
1998-02-19 |
2023-08-12 |
mouse |