Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
A H Koyama, T Arakawa, A Adach. Acceleration of virus-induced apoptosis by tumor necrosis factor. FEBS letters. vol 426. issue 2. 1998-06-02. PMID:9599003. |
comparison of the kinetics of virus multiplication and that of virus-induced apoptosis in the tnf-treated cells revealed that the antiviral effect of tnf is accompanied by a rapid induction of apoptosis in the cells upon infection, suggesting that tnf can inhibit virus multiplication by accelerating an apoptotic response in the infected cells. |
1998-06-02 |
2023-08-12 |
Not clear |
M Zörnig, A O Hueber, G Eva. p53-dependent impairment of T-cell proliferation in FADD dominant-negative transgenic mice. Current biology : CB. vol 8. issue 8. 1998-05-26. PMID:9550704. |
members of the tumour necrosis factor (tnf) receptor family exert pleiotropic effects and can trigger both apoptosis and proliferation [1]. |
1998-05-26 |
2023-08-12 |
mouse |
Y Hitoshi, J Lorens, S I Kitada, J Fisher, M LaBarge, H Z Ring, U Francke, J C Reed, S Kinoshita, G P Nola. Toso, a cell surface, specific regulator of Fas-induced apoptosis in T cells. Immunity. vol 8. issue 4. 1998-05-26. PMID:9586636. |
toso appeared limited to inhibition of apoptosis mediated by members of the tnf receptor family and was capable of inhibiting t cell self-killing induced by tcr activation processes that up-regulate fas ligand. |
1998-05-26 |
2023-08-12 |
Not clear |
A Roulston, C Reinhard, P Amiri, L T William. Early activation of c-Jun N-terminal kinase and p38 kinase regulate cell survival in response to tumor necrosis factor alpha. The Journal of biological chemistry. vol 273. issue 17. 1998-05-22. PMID:9553074. |
stimulation by fas ligand results in apoptosis, whereas tnf induces multiple effects including proliferation, differentiation, and apoptosis. |
1998-05-22 |
2023-08-12 |
Not clear |
A Roulston, C Reinhard, P Amiri, L T William. Early activation of c-Jun N-terminal kinase and p38 kinase regulate cell survival in response to tumor necrosis factor alpha. The Journal of biological chemistry. vol 273. issue 17. 1998-05-22. PMID:9553074. |
activation of the c-jun n-terminal kinase (jnk) and p38 kinase pathways is common to fas and tnf signaling; however, their role in apoptosis is controversial. |
1998-05-22 |
2023-08-12 |
Not clear |
A Roulston, C Reinhard, P Amiri, L T William. Early activation of c-Jun N-terminal kinase and p38 kinase regulate cell survival in response to tumor necrosis factor alpha. The Journal of biological chemistry. vol 273. issue 17. 1998-05-22. PMID:9553074. |
in contrast, tnf requires actinomycin d for apoptosis and activates jnk and p38 kinase with biphasic kinetics. |
1998-05-22 |
2023-08-12 |
Not clear |
A Roulston, C Reinhard, P Amiri, L T William. Early activation of c-Jun N-terminal kinase and p38 kinase regulate cell survival in response to tumor necrosis factor alpha. The Journal of biological chemistry. vol 273. issue 17. 1998-05-22. PMID:9553074. |
thus, early stress kinase activation initiated by tnf plays a key role in regulating apoptosis. |
1998-05-22 |
2023-08-12 |
Not clear |
C Trautwein, T Rakemann, D A Brenner, K Streetz, L Licato, M P Manns, G Tieg. Concanavalin A-induced liver cell damage: activation of intracellular pathways triggered by tumor necrosis factor in mice. Gastroenterology. vol 114. issue 5. 1998-05-22. PMID:9558294. |
concanavalin a (con a) induces tumor necrosis factor (tnf)-dependent hepatocyte apoptosis resembling immune-mediated fulminant hepatic failure in humans. |
1998-05-22 |
2023-08-12 |
mouse |
C Trautwein, T Rakemann, D A Brenner, K Streetz, L Licato, M P Manns, G Tieg. Concanavalin A-induced liver cell damage: activation of intracellular pathways triggered by tumor necrosis factor in mice. Gastroenterology. vol 114. issue 5. 1998-05-22. PMID:9558294. |
intracellular pathways originating at the tnf receptor are either linked to apoptosis, nuclear factor (nf)-kappab translocation, or jun kinase (jnk) activation. |
1998-05-22 |
2023-08-12 |
mouse |
R U Jänicke, M L Sprengart, M R Wati, A G Porte. Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis. The Journal of biological chemistry. vol 273. issue 16. 1998-05-21. PMID:9545256. |
although mcf-7 cells were still sensitive to tumor necrosis factor (tnf)- or staurosporine-induced apoptosis, no dna fragmentation was observed. |
1998-05-21 |
2023-08-12 |
mouse |
N Zhu, A Khoshnan, R Schneider, M Matsumoto, G Dennert, C Ware, M M La. Hepatitis C virus core protein binds to the cytoplasmic domain of tumor necrosis factor (TNF) receptor 1 and enhances TNF-induced apoptosis. Journal of virology. vol 72. issue 5. 1998-05-20. PMID:9557650. |
hepatitis c virus core protein binds to the cytoplasmic domain of tumor necrosis factor (tnf) receptor 1 and enhances tnf-induced apoptosis. |
1998-05-20 |
2023-08-12 |
mouse |
N Zhu, A Khoshnan, R Schneider, M Matsumoto, G Dennert, C Ware, M M La. Hepatitis C virus core protein binds to the cytoplasmic domain of tumor necrosis factor (TNF) receptor 1 and enhances TNF-induced apoptosis. Journal of virology. vol 72. issue 5. 1998-05-20. PMID:9557650. |
we have further shown that stable expression of the core protein in a mouse cell line (bc10me) or human cell lines (hepg2 and hela cells) sensitized them to tnf-induced apoptosis, as determined by the tnf cytotoxicity or annexin v apoptosis assay. |
1998-05-20 |
2023-08-12 |
mouse |
A E Tollefson, T W Hermiston, D L Lichtenstein, C F Colle, R A Tripp, T Dimitrov, K Toth, C E Wells, P C Doherty, W S Wol. Forced degradation of Fas inhibits apoptosis in adenovirus-infected cells. Nature. vol 392. issue 6677. 1998-05-14. PMID:9565035. |
in adenovirus-infected cells, programmed cell death (apoptosis) induced by the cytokine tumour necrosis factor (tnf) is inhibited by several adenovirus-encoded proteins. |
1998-05-14 |
2023-08-12 |
Not clear |
J Delic, P Masdehors, S Omura, J M Cosset, J Dumont, J L Binet, H Magdeléna. The proteasome inhibitor lactacystin induces apoptosis and sensitizes chemo- and radioresistant human chronic lymphocytic leukaemia lymphocytes to TNF-alpha-initiated apoptosis. British journal of cancer. vol 77. issue 7. 1998-05-11. PMID:9569046. |
proteasome inhibition by lactacystin prevents the nuclear translocation of both p50 and p65 nf-kappab subunits and sensitizes these cells to apoptosis by tumour necrosis factor (tnf)-alpha treatment. |
1998-05-11 |
2023-08-12 |
human |
C Rüegg, A Yilmaz, G Bieler, J Bamat, P Chaubert, F J Lejeun. Evidence for the involvement of endothelial cell integrin alphaVbeta3 in the disruption of the tumor vasculature induced by TNF and IFN-gamma. Nature medicine. vol 4. issue 4. 1998-04-29. PMID:9546785. |
detachment and apoptosis of angiogenic endothelial cells was demonstrated in vivo in melanoma metastases of patients treated with tnf and ifn-gamma. |
1998-04-29 |
2023-08-12 |
human |
S M Mariani, P H Kramme. Differential regulation of TRAIL and CD95 ligand in transformed cells of the T and B lymphocyte lineage. European journal of immunology. vol 28. issue 3. 1998-04-23. PMID:9541592. |
trail (apo-2 ligand) and cd95l (cd95/apo-1/fas ligand) share the highest homology among the tnf family members and the ability to induce apoptosis. |
1998-04-23 |
2023-08-12 |
mouse |
W G Telford, S Y Nam, E R Podack, R A Mille. CD30-regulated apoptosis in murine CD8 T cells after cessation of TCR signals. Cellular immunology. vol 182. issue 2. 1998-04-21. PMID:9514701. |
apoptosis induced by agonist withdrawal was not blocked by fas antigen fusion protein or by anti-tnf alpha-neutralizing antibodies, suggesting a mechanism independent of fas/fasl and tnf alpha/tnf-r interactions. |
1998-04-21 |
2023-08-12 |
Not clear |
V Haridas, B G Darnay, K Natarajan, R Heller, B B Aggarwa. Overexpression of the p80 TNF receptor leads to TNF-dependent apoptosis, nuclear factor-kappa B activation, and c-Jun kinase activation. Journal of immunology (Baltimore, Md. : 1950). vol 160. issue 7. 1998-04-21. PMID:9531270. |
overexpression of the p80 tnf receptor leads to tnf-dependent apoptosis, nuclear factor-kappa b activation, and c-jun kinase activation. |
1998-04-21 |
2023-08-12 |
Not clear |
V Haridas, B G Darnay, K Natarajan, R Heller, B B Aggarwa. Overexpression of the p80 TNF receptor leads to TNF-dependent apoptosis, nuclear factor-kappa B activation, and c-Jun kinase activation. Journal of immunology (Baltimore, Md. : 1950). vol 160. issue 7. 1998-04-21. PMID:9531270. |
hela cells, which express only p60 receptors, were transfected with p80 receptor cdna and then examined for apoptosis, nf-kappa b activation, and c-jun kinase activation induced by tnf and by p60 or p80 receptor-specific muteins. |
1998-04-21 |
2023-08-12 |
Not clear |
V Haridas, B G Darnay, K Natarajan, R Heller, B B Aggarwa. Overexpression of the p80 TNF receptor leads to TNF-dependent apoptosis, nuclear factor-kappa B activation, and c-Jun kinase activation. Journal of immunology (Baltimore, Md. : 1950). vol 160. issue 7. 1998-04-21. PMID:9531270. |
the p80 mutein, like tnf and the p60 mutein, induced apoptosis and activation of nf-kappa b and c-jun kinase in cells overexpressing recombinant p80 receptor but had no effect on cells expressing a high level of endogenous p80 receptor. |
1998-04-21 |
2023-08-12 |
Not clear |