| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L C Penning, R G Schipper, D Vercammen, A A Verhofstad, T Denecker, R Beyaert, P Vandenabeel. Sensitization of tnf-induced apoptosis with polyamine synthesis inhibitors in different human and murine tumour cell lines. Cytokine. vol 10. issue 6. 1998-07-15. PMID:9632528. |
rat/mouse t cell hybridoma-derived pc60 r55/r75 cells were used as a model to study tumour necrosis factor (tnf)-induced apoptosis. |
1998-07-15 |
2023-08-12 |
human |
| L C Penning, R G Schipper, D Vercammen, A A Verhofstad, T Denecker, R Beyaert, P Vandenabeel. Sensitization of tnf-induced apoptosis with polyamine synthesis inhibitors in different human and murine tumour cell lines. Cytokine. vol 10. issue 6. 1998-07-15. PMID:9632528. |
these results suggest that a decrease of intracellular spm levels rather then odc activity per se is involved in the sensitization towards apoptosis induced by tnf or alphafas. |
1998-07-15 |
2023-08-12 |
human |
| W Declercq, G Denecker, W Fiers, P Vandenabeel. Cooperation of both TNF receptors in inducing apoptosis: involvement of the TNF receptor-associated factor binding domain of the TNF receptor 75. Journal of immunology (Baltimore, Md. : 1950). vol 161. issue 1. 1998-07-09. PMID:9647248. |
cooperation of both tnf receptors in inducing apoptosis: involvement of the tnf receptor-associated factor binding domain of the tnf receptor 75. |
1998-07-09 |
2023-08-12 |
Not clear |
| H Qian, G J Hausman, M M Compton, M J Azain, D L Hartzell, C A Bail. Leptin regulation of peroxisome proliferator-activated receptor-gamma, tumor necrosis factor, and uncoupling protein-2 expression in adipose tissues. Biochemical and biophysical research communications. vol 246. issue 3. 1998-07-02. PMID:9618269. |
the present study suggests that expression of ppar gamma may be directly involved in the leptin-induced adipocyte apoptosis signal pathway, whereas ucp2 and tnf alpha may play roles in the leptin-induced lipolysis process. |
1998-07-02 |
2023-08-12 |
rat |
| D K Giri, B B Aggarwa. Constitutive activation of NF-kappaB causes resistance to apoptosis in human cutaneous T cell lymphoma HuT-78 cells. Autocrine role of tumor necrosis factor and reactive oxygen intermediates. The Journal of biological chemistry. vol 273. issue 22. 1998-07-01. PMID:9593751. |
in the present report, we investigated apoptosis induction by tumor necrosis factor (tnf) in two human t cell lines, jurkat and hut-78. |
1998-07-01 |
2023-08-12 |
human |
| D K Giri, B B Aggarwa. Constitutive activation of NF-kappaB causes resistance to apoptosis in human cutaneous T cell lymphoma HuT-78 cells. Autocrine role of tumor necrosis factor and reactive oxygen intermediates. The Journal of biological chemistry. vol 273. issue 22. 1998-07-01. PMID:9593751. |
overall, these results suggest that constitutive activation of nf-kappab, tnf, and prooxidant pathway in certain t cell lymphomas causes resistance to apoptosis, and this can be reversed by antioxidants. |
1998-07-01 |
2023-08-12 |
human |
| G Senaldi, C L Shaklee, B Simon, C G Rowan, D L Lacey, T Hartun. Keratinocyte growth factor protects murine hepatocytes from tumor necrosis factor-induced apoptosis in vivo and in vitro. Hepatology (Baltimore, Md.). vol 27. issue 6. 1998-06-30. PMID:9620331. |
mechanistically, lps-induced tumor necrosis factor (tnf) triggers hepatocyte apoptosis, which is enhanced by galn-arrested transcription. |
1998-06-30 |
2023-08-12 |
mouse |
| G Senaldi, C L Shaklee, B Simon, C G Rowan, D L Lacey, T Hartun. Keratinocyte growth factor protects murine hepatocytes from tumor necrosis factor-induced apoptosis in vivo and in vitro. Hepatology (Baltimore, Md.). vol 27. issue 6. 1998-06-30. PMID:9620331. |
similarly, the combination of tnf and actinomycin d (actd) causes hepatocyte apoptosis in vitro. |
1998-06-30 |
2023-08-12 |
mouse |
| T Takehara, N Hayashi, E Mita, T Kanto, T Tatsumi, Y Sasaki, A Kasahara, M Hor. Delayed Fas-mediated hepatocyte apoptosis during liver regeneration in mice: hepatoprotective role of TNF alpha. Hepatology (Baltimore, Md.). vol 27. issue 6. 1998-06-30. PMID:9620338. |
delayed fas-mediated hepatocyte apoptosis during liver regeneration in mice: hepatoprotective role of tnf alpha. |
1998-06-30 |
2023-08-12 |
mouse |
| T Takehara, N Hayashi, E Mita, T Kanto, T Tatsumi, Y Sasaki, A Kasahara, M Hor. Delayed Fas-mediated hepatocyte apoptosis during liver regeneration in mice: hepatoprotective role of TNF alpha. Hepatology (Baltimore, Md.). vol 27. issue 6. 1998-06-30. PMID:9620338. |
these results indicate that fas-signaling events at the level or upstream of caspase-3-like protease are suppressed during liver regeneration, resulting in delayed hepatocyte apoptosis, and also that tnf alpha acts as one of the protective factors against fas-mediated hepatocyte apoptosis. |
1998-06-30 |
2023-08-12 |
mouse |
| S K Manna, H J Zhang, T Yan, L W Oberley, B B Aggarwa. Overexpression of manganese superoxide dismutase suppresses tumor necrosis factor-induced apoptosis and activation of nuclear transcription factor-kappaB and activated protein-1. The Journal of biological chemistry. vol 273. issue 21. 1998-06-25. PMID:9582369. |
several recently identified intracellular proteins associate with the tumor necrosis factor (tnf) receptor and activate nuclear transcription factor (nf)-kappab, c-jun kinase, and apoptosis. |
1998-06-25 |
2023-08-12 |
human |
| S K Manna, H J Zhang, T Yan, L W Oberley, B B Aggarwa. Overexpression of manganese superoxide dismutase suppresses tumor necrosis factor-induced apoptosis and activation of nuclear transcription factor-kappaB and activated protein-1. The Journal of biological chemistry. vol 273. issue 21. 1998-06-25. PMID:9582369. |
overall, these results demonstrate that, in addition to several recently identified signaling molecules, reactive oxygen intermediates play a critical role in activation of nf-kappab, activated protein-1, c-jun kinase, and apoptosis induced by tnf and other agents. |
1998-06-25 |
2023-08-12 |
human |
| M Saitoh, H Nishitoh, M Fujii, K Takeda, K Tobiume, Y Sawada, M Kawabata, K Miyazono, H Ichij. Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1. The EMBO journal. vol 17. issue 9. 1998-06-18. PMID:9564042. |
apoptosis signal-regulating kinase (ask) 1 was recently identified as a mitogen-activated protein (map) kinase kinase kinase which activates the c-jun n-terminal kinase (jnk) and p38 map kinase pathways and is required for tumor necrosis factor (tnf)-alpha-induced apoptosis; however, the mechanism regulating ask1 activity is unknown. |
1998-06-18 |
2023-08-12 |
Not clear |
| M Oddo, T Renno, A Attinger, T Bakker, H R MacDonald, P R Meyla. Fas ligand-induced apoptosis of infected human macrophages reduces the viability of intracellular Mycobacterium tuberculosis. Journal of immunology (Baltimore, Md. : 1950). vol 160. issue 11. 1998-06-11. PMID:9605147. |
these data suggest that apoptosis of infected macrophages induced through receptors of the tnf family could be an immune effector mechanism not only depriving mycobacteria from their growth environment but also reducing viable bacterial counts by an unknown mechanism. |
1998-06-11 |
2023-08-12 |
human |
| W Wuttke, L Pitzel, I Knoke, K Theiling, H Jarr. Immune-endocrine interactions affecting luteal function in pigs. Journal of reproduction and fertility. Supplement. vol 52. 1998-06-09. PMID:9602717. |
furthermore, tnf alpha stimulates programmed cell death (apoptosis) in luteal cells kept under culture conditions. |
1998-06-09 |
2023-08-12 |
Not clear |
| Y Jiang, A G Porte. Prevention of tumor necrosis factor (TNF)-mediated induction of p21WAF1/CIP1 sensitizes MCF-7 carcinoma cells to TNF-induced apoptosis. Biochemical and biophysical research communications. vol 245. issue 3. 1998-06-05. PMID:9588176. |
prevention of tumor necrosis factor (tnf)-mediated induction of p21waf1/cip1 sensitizes mcf-7 carcinoma cells to tnf-induced apoptosis. |
1998-06-05 |
2023-08-12 |
Not clear |
| Y Jiang, A G Porte. Prevention of tumor necrosis factor (TNF)-mediated induction of p21WAF1/CIP1 sensitizes MCF-7 carcinoma cells to TNF-induced apoptosis. Biochemical and biophysical research communications. vol 245. issue 3. 1998-06-05. PMID:9588176. |
the mcf-7 breast carcinoma and mrc-5 lung fibroblast cell lines are sensitive and resistant to tumor necrosis factor (tnf)-induced apoptosis, respectively. |
1998-06-05 |
2023-08-12 |
Not clear |
| S C Wright, U Schellenberger, H Wang, Y Wang, D H Kinde. Chemotherapeutic drug activation of the AP24 protease in apoptosis: requirement for caspase 3-like-proteases. Biochemical and biophysical research communications. vol 245. issue 3. 1998-06-05. PMID:9588194. |
ap24 is a serine protease that is activated during tnf or uv light-induced apoptosis and stimulates dna fragmentation in isolated nuclei. |
1998-06-05 |
2023-08-12 |
Not clear |
| P Pantazis, A DeJesus, J Early, B Giovanell. Altered sensitivities to anticancer and differentiation agents in etoposide-resistant human myeloid leukemia U-937 cells. Journal of hematotherapy. vol 7. issue 1. 1998-06-04. PMID:9507384. |
further, the u-937/re cells exhibit differential sensitivities to compounds that induce maturation of u-937 cells, as judged by the ability to reduce nitroblue tetrazolium and by morphologic changes, and increased sensitivities to apoptosis induction by the cytokines tumor necrosis factor (tnf) and lymphotoxin (lt) and the anticancer drugs 9-nitrocamptothecin and doxorubicin. |
1998-06-04 |
2023-08-12 |
mouse |
| S M Mariani, P H Kramme. Surface expression of TRAIL/Apo-2 ligand in activated mouse T and B cells. European journal of immunology. vol 28. issue 5. 1998-06-03. PMID:9603453. |
like other members of the tnf family, trail/apo-2 ligand induces apoptosis in sensitive target cells in a caspase-dependent fashion. |
1998-06-03 |
2023-08-12 |
mouse |