| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J Shi, B H Sun, L R Zhou, X S Wan. Role of IL-10 and TNF-α during Mycobacterium tuberculosis infection in murine alveolar macrophages. Genetics and molecular research : GMR. vol 15. issue 3. 2017-02-27. PMID:27706765. |
taken together, our results suggest that the stat3 signaling pathway might play a key role in the regulation of cell proliferation and alveolar macrophage apoptosis in response to mtb. |
2017-02-27 |
2023-08-13 |
mouse |
| Li Shen, Guangshun Zhang, Zhaohuan Lou, Guanhua Xu, Guangji Zhan. Cryptotanshinone enhances the effect of Arsenic trioxide in treating liver cancer cell by inducing apoptosis through downregulating phosphorylated- STAT3 in vitro and in vivo. BMC complementary and alternative medicine. vol 17. issue 1. 2017-02-24. PMID:28187727. |
cryptotanshinone enhances the effect of arsenic trioxide in treating liver cancer cell by inducing apoptosis through downregulating phosphorylated- stat3 in vitro and in vivo. |
2017-02-24 |
2023-08-13 |
Not clear |
| Juan Peng, Qiongyao Wang, Huanxin Liu, Minting Ye, Xiaoxia Wu, Linlang Gu. EPHA3 regulates the multidrug resistance of small cell lung cancer via the PI3K/BMX/STAT3 signaling pathway. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 37. issue 9. 2017-02-16. PMID:27101199. |
to explore the possible role of epha3 in mdr, we assessed the influence of epha3 on chemoresistance, cell cycle, apoptosis, and tumor growth, as well as the relationship between epha3 and the expression of pi3k, bmx, and stat3 in sclc. |
2017-02-16 |
2023-08-13 |
Not clear |
| Suman Labala, Anup Jose, Venkata Vamsi Krishna Venugant. Transcutaneous iontophoretic delivery of STAT3 siRNA using layer-by-layer chitosan coated gold nanoparticles to treat melanoma. Colloids and surfaces. B, Biointerfaces. vol 146. 2017-02-10. PMID:27318964. |
overexpression of signal transducer and activator of transcription 3 (stat3) protein prevents apoptosis and enhances proliferation of melanocytes. |
2017-02-10 |
2023-08-13 |
Not clear |
| Suman Labala, Anup Jose, Venkata Vamsi Krishna Venugant. Transcutaneous iontophoretic delivery of STAT3 siRNA using layer-by-layer chitosan coated gold nanoparticles to treat melanoma. Colloids and surfaces. B, Biointerfaces. vol 146. 2017-02-10. PMID:27318964. |
similarly, apoptosis assay showed 29% and 44% of early and late apoptotic events, respectively after treatment with stat3 sirna loaded lbl-aunp. |
2017-02-10 |
2023-08-13 |
Not clear |
| Shaojun Wang, Jun Zhou, Weijie Kang, Zhaoni Dong, Hezuo Wan. Tocilizumab inhibits neuronal cell apoptosis and activates STAT3 in cerebral infarction rat model. Bosnian journal of basic medical sciences. vol 16. issue 2. 2017-02-09. PMID:26773188. |
tocilizumab inhibits neuronal cell apoptosis and activates stat3 in cerebral infarction rat model. |
2017-02-09 |
2023-08-13 |
rat |
| Xin Wang, Hongtao Liu, Xiaqing Zhang, Xiaojuan Li, Hao Gu, Heng Zhang, Ruitai Fa. G6PD downregulation triggered growth inhibition and induced apoptosis by regulating STAT3 signaling pathway in esophageal squamous cell carcinoma. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 37. issue 1. 2017-02-06. PMID:26250461. |
g6pd downregulation triggered growth inhibition and induced apoptosis by regulating stat3 signaling pathway in esophageal squamous cell carcinoma. |
2017-02-06 |
2023-08-13 |
mouse |
| Wenbin Zhou, Xingjie Bi, Guojun Gao, Lijiang Su. miRNA-133b and miRNA-135a induce apoptosis via the JAK2/STAT3 signaling pathway in human renal carcinoma cells. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 84. 2017-02-03. PMID:27710896. |
our results demonstrate that mir-133b and mir-135a which are down-regulated in wildtype and mutated ccrccs, induce apoptosis in vitro by a signaling cascade involving jak2, stat3 and bcl-2. |
2017-02-03 |
2023-08-13 |
human |
| Na Shen, Xinsheng Huang, Jun L. Upregulation of miR-129-5p affects laryngeal cancer cell proliferation, invasiveness, and migration by affecting STAT3 expression. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 37. issue 2. 2017-01-30. PMID:26318305. |
cell proliferation, invasion, migration, cell cycle, and apoptosis assays were used to determine the role of mirna-129-5p in the growth, invasion, and migration of lscc cells and to determine the importance of stat3 in these effects. |
2017-01-30 |
2023-08-13 |
Not clear |
| E D Bazhanova, V N Anisimo. The role of STAT transcription factors in apoptosis regulation of hypothalamic neurons in aging in HER-2/neu transgenic mice and wild-type FVB/N mice. Doklady. Biochemistry and biophysics. vol 468. issue 1. 2017-01-25. PMID:27417725. |
we showed that suppression of stat3, stat5, and stat6 and overexpression of the proapoptotic factor stat1, which provides p53-mediated apoptosis, are the causes for increasing the number of apoptotic neurons in physiological aging. |
2017-01-25 |
2023-08-13 |
mouse |
| Junwei Zhang, Jiajun Du, Qi Liu, Yi Zhan. Down-regulation of STAT3 expression using vector-based RNA interference promotes apoptosis in Hepatocarcinoma cells. Artificial cells, nanomedicine, and biotechnology. vol 44. issue 5. 2017-01-12. PMID:26134753. |
down-regulation of stat3 expression using vector-based rna interference promotes apoptosis in hepatocarcinoma cells. |
2017-01-12 |
2023-08-13 |
Not clear |
| Junwei Zhang, Jiajun Du, Qi Liu, Yi Zhan. Down-regulation of STAT3 expression using vector-based RNA interference promotes apoptosis in Hepatocarcinoma cells. Artificial cells, nanomedicine, and biotechnology. vol 44. issue 5. 2017-01-12. PMID:26134753. |
in this study, we followed a dna vector-based rnai approach to silence the signal transducer and activator of transcription 3 (stat3) expression in bel-7402 cells, to explore how the janus kinase (jak)/stat3 signaling pathway influences the apoptosis of hepatocarcinoma cells. |
2017-01-12 |
2023-08-13 |
Not clear |
| Zubin Zhang, Hongwu Mao, Xiaolin Du, Jingyu Zhu, Yujia Xu, Siyu Wang, Xin Xu, Peng Ji, Yang Yu, Biyin Cao, Kunkun Han, Tingjun Hou, Zhuan Xu, Yan Kong, Gaofeng Jiang, Xiaowen Tang, Chunhua Qiao, Xinliang Ma. A novel small molecule agent displays potent anti-myeloma activity by inhibiting the JAK2-STAT3 signaling pathway. Oncotarget. vol 7. issue 8. 2017-01-06. PMID:26814430. |
by inhibiting the stat3 signaling, sc99 induced mm cell apoptosis which could be partly abolished by the ectopic expression of stat3. |
2017-01-06 |
2023-08-13 |
mouse |
| Chuntao Wu, Jinji Zhang, Tienan Liu, Guimei Jiao, Changzai Li, Baoshan H. [Astaxanthin inhibits proliferation and promotes apoptosis of A549 lung cancer cells via blocking JAK1/STAT3 pathway]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. vol 32. issue 6. 2017-01-06. PMID:27371847. |
the viability of a549 cells was detected by cck-8 assay; cell cycle and apoptosis were observed by flow cytometry; and the expressions of b-cell lymphoma-2 (bcl-2), bcl-2 associated x protein (bax), signal transducers and activators of transcription 3 (stat3), and janus kinase 1 (jak1) were evaluated by western blotting. |
2017-01-06 |
2023-08-13 |
Not clear |
| Lei Wang, Yanbo Liu, Xinli Zhao, Weigao She. [Knockdown of STAT3 reduces the level of survivin and promotes the apoptosis of U87MG glioma cells]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. vol 32. issue 6. 2017-01-06. PMID:27371848. |
[knockdown of stat3 reduces the level of survivin and promotes the apoptosis of u87mg glioma cells]. |
2017-01-06 |
2023-08-13 |
human |
| Lei Wang, Yanbo Liu, Xinli Zhao, Weigao She. [Knockdown of STAT3 reduces the level of survivin and promotes the apoptosis of U87MG glioma cells]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. vol 32. issue 6. 2017-01-06. PMID:27371848. |
objective to investigate the effect of signal transducer and activator of transcription (stat3)-specific sirna (sistat3) on the apoptosis of u87mg human glioma cells and its mechanism. |
2017-01-06 |
2023-08-13 |
human |
| Lei Wang, Yanbo Liu, Xinli Zhao, Weigao She. [Knockdown of STAT3 reduces the level of survivin and promotes the apoptosis of U87MG glioma cells]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. vol 32. issue 6. 2017-01-06. PMID:27371848. |
conclusion knockdown of stat3 in u87mg cells can downregulate the level of survivin and remarkably promote the apoptosis of glioma cells. |
2017-01-06 |
2023-08-13 |
human |
| Shengjun Ji, Yeliang Wen, Qiting Lai, Minjing Li, Peifang Zhan. [Hypoxia combined with TNF-α induces apoptosis of cultured human pulmonary microvascular endothelial cells via activation of the STAT3 rather than ERK1/2 signaling pathway]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. vol 32. issue 7. 2017-01-03. PMID:27363268. |
[hypoxia combined with tnf-α induces apoptosis of cultured human pulmonary microvascular endothelial cells via activation of the stat3 rather than erk1/2 signaling pathway]. |
2017-01-03 |
2023-08-13 |
human |
| Shengjun Ji, Yeliang Wen, Qiting Lai, Minjing Li, Peifang Zhan. [Hypoxia combined with TNF-α induces apoptosis of cultured human pulmonary microvascular endothelial cells via activation of the STAT3 rather than ERK1/2 signaling pathway]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. vol 32. issue 7. 2017-01-03. PMID:27363268. |
moreover, the stat3 inhibitor s3i-201 reduced the apoptosis rate in the combined treatment group. |
2017-01-03 |
2023-08-13 |
human |
| Shengjun Ji, Yeliang Wen, Qiting Lai, Minjing Li, Peifang Zhan. [Hypoxia combined with TNF-α induces apoptosis of cultured human pulmonary microvascular endothelial cells via activation of the STAT3 rather than ERK1/2 signaling pathway]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. vol 32. issue 7. 2017-01-03. PMID:27363268. |
conclusion combined hypoxia and tnf-α could promote hpmvec apoptosis by activating stat3 rather than erk1/2. |
2017-01-03 |
2023-08-13 |
human |