| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sheng-An Su, Du Yang, Wei Zhu, Zhejun Cai, Na Zhang, Lina Zhao, Jian-An Wang, Meixiang Xian. Interleukin-17A mediates cardiomyocyte apoptosis through Stat3-iNOS pathway. Biochimica et biophysica acta. vol 1863. issue 11. 2017-06-26. PMID:27566322. |
finally, using an in vivo myocardial ischemia/reperfusion injury model, we verified that stat3 inhibition increased inos expression and exacerbated cardiomyocyte apoptosis. |
2017-06-26 |
2023-08-13 |
mouse |
| Sheng-An Su, Du Yang, Wei Zhu, Zhejun Cai, Na Zhang, Lina Zhao, Jian-An Wang, Meixiang Xian. Interleukin-17A mediates cardiomyocyte apoptosis through Stat3-iNOS pathway. Biochimica et biophysica acta. vol 1863. issue 11. 2017-06-26. PMID:27566322. |
thus, our data strongly support the notion that stat3 plays a compensatory anti-apoptotic role in il-17a/inos-mediated cardiomyocyte apoptosis via inhibiting inos transcription, providing a novel molecular mechanism of apoptosis regulation and complicated interactions between il-17a/inos and il-17a/stat3 signalings. |
2017-06-26 |
2023-08-13 |
mouse |
| Xiaojuan Wu, Yang Cao, Hui Xiao, Chenglong Li, Jiayuh Li. Bazedoxifene as a Novel GP130 Inhibitor for Pancreatic Cancer Therapy. Molecular cancer therapeutics. vol 15. issue 11. 2017-06-15. PMID:27535971. |
here, we observed bazedoxifene inhibited stat3 phosphorylation and stat3 dna binding, induced apoptosis, and suppressed tumor growth in pancreatic cancer cells with persistent il6/gp130/stat3 signaling in vitro and in vivo in addition, il6, but not infγ, rescued bazedoxifene-mediated reduction of cell viability. |
2017-06-15 |
2023-08-13 |
mouse |
| Patrick Geraghty, Eran Hadas, Boe-Hyun Kim, Abdoulaye J Dabo, David J Volsky, Robert Foronj. HIV infection model of chronic obstructive pulmonary disease in mice. American journal of physiology. Lung cellular and molecular physiology. vol 312. issue 4. 2017-06-12. PMID:28104604. |
these changes coincided with enhanced iκbα, erk1/2, p38, and stat3 phosphorylation and lung cell apoptosis. |
2017-06-12 |
2023-08-13 |
mouse |
| Chunwa Jiang, Muqaddas Masood, Azhar Rasul, Wei Wei, Ya Wang, Muhammad Ali, Muhammad Mustaqeem, Jiang Li, Xiaomeng L. Altholactone Inhibits NF-κB and STAT3 Activation and Induces Reactive Oxygen Species-Mediated Apoptosis in Prostate Cancer DU145 Cells. Molecules (Basel, Switzerland). vol 22. issue 2. 2017-06-05. PMID:28178219. |
altholactone inhibits nf-κb and stat3 activation and induces reactive oxygen species-mediated apoptosis in prostate cancer du145 cells. |
2017-06-05 |
2023-08-13 |
Not clear |
| Yinzi Liu, Diane S Sepich, Lilianna Solnica-Kreze. Stat3/Cdc25a-dependent cell proliferation promotes embryonic axis extension during zebrafish gastrulation. PLoS genetics. vol 13. issue 2. 2017-05-26. PMID:28222105. |
zebrafish embryos lacking maternal and zygotic stat3 expression exhibit normal convergence movements and planar cell polarity signaling, but transient axis elongation defect due to insufficient number of cells resulting largely from reduced cell proliferation and increased apoptosis. |
2017-05-26 |
2023-08-13 |
human |
| Do-Hee Kim, Ki-Woong Park, In Gyeong Chae, Juthika Kundu, Eun-Hee Kim, Joydeb Kumar Kundu, Kyung-Soo Chu. Carnosic acid inhibits STAT3 signaling and induces apoptosis through generation of ROS in human colon cancer HCT116 cells. Molecular carcinogenesis. vol 55. issue 6. 2017-05-23. PMID:26152521. |
carnosic acid inhibits stat3 signaling and induces apoptosis through generation of ros in human colon cancer hct116 cells. |
2017-05-23 |
2023-08-13 |
human |
| Do-Hee Kim, Ki-Woong Park, In Gyeong Chae, Juthika Kundu, Eun-Hee Kim, Joydeb Kumar Kundu, Kyung-Soo Chu. Carnosic acid inhibits STAT3 signaling and induces apoptosis through generation of ROS in human colon cancer HCT116 cells. Molecular carcinogenesis. vol 55. issue 6. 2017-05-23. PMID:26152521. |
in conclusion, our study provides the first report that ca induced apoptosis in hct116 cells via generation of ros, induction of p53, activation of caspases, and inhibition of stat3 signaling pathway. |
2017-05-23 |
2023-08-13 |
human |
| Li Qiao, Zhusong Mei, Zhiyong Yang, Xinji Li, Hong Cai, Wei Li. ALA-PDT inhibits proliferation and promotes apoptosis of SCC cells through STAT3 signal pathway. Photodiagnosis and photodynamic therapy. vol 14. 2017-05-17. PMID:26805005. |
ala-pdt inhibits proliferation and promotes apoptosis of scc cells through stat3 signal pathway. |
2017-05-17 |
2023-08-13 |
Not clear |
| Li Qiao, Zhusong Mei, Zhiyong Yang, Xinji Li, Hong Cai, Wei Li. ALA-PDT inhibits proliferation and promotes apoptosis of SCC cells through STAT3 signal pathway. Photodiagnosis and photodynamic therapy. vol 14. 2017-05-17. PMID:26805005. |
ala-pdt could inhibit proliferation of a431 and colo-16 cells, stat3 knock down could enhance ala-pdt's inhibition of cell proliferation, and promote apoptosis induced by ala-pdt. |
2017-05-17 |
2023-08-13 |
Not clear |
| Chunwei Lv, Qunshu Su, Yupei Liang, Jinqing Hu, Sujing Yua. Oncolytic vaccine virus harbouring the IL-24 gene suppresses the growth of lung cancer by inducing apoptosis. Biochemical and biophysical research communications. vol 476. issue 1. 2017-05-16. PMID:27208781. |
interleukin-24 (il-24/mda-7) is an important cytokine that belongs to the activating caspase family and facilitates the inhibition of stat3 when a cell enters the apoptosis pathway. |
2017-05-16 |
2023-08-13 |
human |
| Chunwei Lv, Qunshu Su, Yupei Liang, Jinqing Hu, Sujing Yua. Oncolytic vaccine virus harbouring the IL-24 gene suppresses the growth of lung cancer by inducing apoptosis. Biochemical and biophysical research communications. vol 476. issue 1. 2017-05-16. PMID:27208781. |
our results showed that vv-il-24 efficiently infected and destroyed lung cancer cells via caspase-dependent apoptosis and decreased the expression of stat3. |
2017-05-16 |
2023-08-13 |
human |
| Chunwei Lv, Qunshu Su, Yupei Liang, Jinqing Hu, Sujing Yua. Oncolytic vaccine virus harbouring the IL-24 gene suppresses the growth of lung cancer by inducing apoptosis. Biochemical and biophysical research communications. vol 476. issue 1. 2017-05-16. PMID:27208781. |
in vivo, vv-il-24 expressed il-24 at a high level in the transplanted tumour, reduced stat3 activity, and eventually led to apoptosis. |
2017-05-16 |
2023-08-13 |
human |
| Jiayu Diao, Jin Wei, Rui Yan, Xin Liu, Qing Li, Lin Lin, Yanhe Zhu, Hong L. Rosmarinic Acid suppressed high glucose-induced apoptosis in H9c2 cells by ameliorating the mitochondrial function and activating STAT3. Biochemical and biophysical research communications. vol 477. issue 4. 2017-05-15. PMID:27402269. |
rosmarinic acid suppressed high glucose-induced apoptosis in h9c2 cells by ameliorating the mitochondrial function and activating stat3. |
2017-05-15 |
2023-08-13 |
Not clear |
| Jiayu Diao, Jin Wei, Rui Yan, Xin Liu, Qing Li, Lin Lin, Yanhe Zhu, Hong L. Rosmarinic Acid suppressed high glucose-induced apoptosis in H9c2 cells by ameliorating the mitochondrial function and activating STAT3. Biochemical and biophysical research communications. vol 477. issue 4. 2017-05-15. PMID:27402269. |
the present study was undertaken to determine the relationship between ra and stat3 activation, as well as their effects on high glucose-induced mitochondrial injury and apoptosis in h9c2 cardiomyocyte. |
2017-05-15 |
2023-08-13 |
Not clear |
| Jiayu Diao, Jin Wei, Rui Yan, Xin Liu, Qing Li, Lin Lin, Yanhe Zhu, Hong L. Rosmarinic Acid suppressed high glucose-induced apoptosis in H9c2 cells by ameliorating the mitochondrial function and activating STAT3. Biochemical and biophysical research communications. vol 477. issue 4. 2017-05-15. PMID:27402269. |
importantly, inhibition of stat3 expression by using stat3-sirna partly suppressed the effect of ra on high glucose-induced apoptosis. |
2017-05-15 |
2023-08-13 |
Not clear |
| Jiayu Diao, Jin Wei, Rui Yan, Xin Liu, Qing Li, Lin Lin, Yanhe Zhu, Hong L. Rosmarinic Acid suppressed high glucose-induced apoptosis in H9c2 cells by ameliorating the mitochondrial function and activating STAT3. Biochemical and biophysical research communications. vol 477. issue 4. 2017-05-15. PMID:27402269. |
taken together, pretreatment with ra suppressed high glucose-induced apoptosis in cardiomyocyte by ameliorating mitochondrial function and activating stat3. |
2017-05-15 |
2023-08-13 |
Not clear |
| Sanya-Eduarda Kuzet, Cedric Gaggiol. Fibroblast activation in cancer: when seed fertilizes soil. Cell and tissue research. vol 365. issue 3. 2017-05-15. PMID:27474009. |
upon lif stimulation, jak is phosphorylated and further activates stat3, a transcriptional factor that is then translocated into the nucleus where it promotes the transcription of genes responsible for cell growth, differentiation, proliferation and apoptosis. |
2017-05-15 |
2023-08-13 |
Not clear |
| M A Crookenden, A Heiser, A Murray, V S R Dukkipati, J K Kay, J J Loor, S Meier, M D Mitchell, K M Moyes, C G Walker, J R Roch. Parturition in dairy cows temporarily alters the expression of genes in circulating neutrophils. Journal of dairy science. vol 99. issue 8. 2017-05-12. PMID:27179873. |
genes that were differentially expressed over the transition period included those involved in neutrophil adhesion (sell, itgb2, and itgbx), mediation of the immune response (tlr4, hla-dra, and cxcr2), maturation, cell cycle progression, apoptosis (mcl1, bcl2, faslg, and ripk1), and control of gene expression (pparg, ppard, and stat3). |
2017-05-12 |
2023-08-13 |
Not clear |
| Xing Bao, Tingting Ren, Yi Huang, Chongmin Ren, Kang Yang, Hongliang Zhang, Wei Gu. Bortezomib induces apoptosis and suppresses cell growth and metastasis by inactivation of Stat3 signaling in chondrosarcoma. International journal of oncology. vol 50. issue 2. 2017-04-27. PMID:28000897. |
bortezomib induces apoptosis and suppresses cell growth and metastasis by inactivation of stat3 signaling in chondrosarcoma. |
2017-04-27 |
2023-08-13 |
Not clear |