| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tingting Yao, Rongbiao Lu, Jun Zhang, Xingyu Fang, Li Fan, Chunxian Huang, Rongchun Lin, Zhongqiu Li. Growth arrest-specific 5 attenuates cisplatin-induced apoptosis in cervical cancer by regulating STAT3 signaling via miR-21. Journal of cellular physiology. vol 234. issue 6. 2020-04-13. PMID:30352127. |
growth arrest-specific 5 attenuates cisplatin-induced apoptosis in cervical cancer by regulating stat3 signaling via mir-21. |
2020-04-13 |
2023-08-13 |
human |
| Patrycja Kurowska, Ewa Mlyczyńska, Monika Dawid, Małgorzata Opydo-Chanek, Joelle Dupont, Agnieszka Ra. In Vitro Effects of Vaspin on Porcine Granulosa Cell Proliferation, Cell Cycle Progression, and Apoptosis by Activation of GRP78 Receptor and Several Kinase Signaling Pathways Including MAP3/1, AKT, and STAT3. International journal of molecular sciences. vol 20. issue 22. 2020-04-07. PMID:31752432. |
in vitro effects of vaspin on porcine granulosa cell proliferation, cell cycle progression, and apoptosis by activation of grp78 receptor and several kinase signaling pathways including map3/1, akt, and stat3. |
2020-04-07 |
2023-08-13 |
Not clear |
| Zi-Fei Zhou, Tuan-Wei Sun, Yun-Hao Qin, Ying-Jie Zhu, Ying-Ying Jiang, Yang Zhang, Jun-Jian Liu, Jin Wu, Shi-Sheng He, Feng Che. Selenium-doped hydroxyapatite biopapers with an anti-bone tumor effect by inducing apoptosis. Biomaterials science. vol 7. issue 12. 2020-04-01. PMID:31552923. |
the results demonstrate that se-ha/cs biopapers may inhibit the growth of hcs 2/8 and sjsa cells by synchronously inducing jnk activation and stat3 inhibition and consequently promote the apoptosis of these cells. |
2020-04-01 |
2023-08-13 |
human |
| Jianchu Wang, Libai Lu, Zongjiang Luo, Wenchuan Li, Yuan Lu, Qianli Tang, Jian P. miR-383 inhibits cell growth and promotes cell apoptosis in hepatocellular carcinoma by targeting IL-17 via STAT3 signaling pathway. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 120. 2020-03-31. PMID:31648164. |
mir-383 inhibits cell growth and promotes cell apoptosis in hepatocellular carcinoma by targeting il-17 via stat3 signaling pathway. |
2020-03-31 |
2023-08-13 |
Not clear |
| Yan-Qing Zang, Yan-Yu Feng, Ying-Hua Luo, Yu-Qing Zhai, Xue-Ying Ju, Yu-Chao Feng, Ya-Nan Sheng, Jia-Ru Wang, Chang-Qing Yu, Cheng-Hao Ji. Quinalizarin induces ROS‑mediated apoptosis via the MAPK, STAT3 and NF‑κB signaling pathways in human breast cancer cells. Molecular medicine reports. vol 20. issue 5. 2020-03-31. PMID:31702038. |
quinalizarin induces ros‑mediated apoptosis via the mapk, stat3 and nf‑κb signaling pathways in human breast cancer cells. |
2020-03-31 |
2023-08-13 |
human |
| Yan-Qing Zang, Yan-Yu Feng, Ying-Hua Luo, Yu-Qing Zhai, Xue-Ying Ju, Yu-Chao Feng, Ya-Nan Sheng, Jia-Ru Wang, Chang-Qing Yu, Cheng-Hao Ji. Quinalizarin induces ROS‑mediated apoptosis via the MAPK, STAT3 and NF‑κB signaling pathways in human breast cancer cells. Molecular medicine reports. vol 20. issue 5. 2020-03-31. PMID:31702038. |
the results from the present study suggested that quinalizarin induced g2/m phase cell cycle arrest and apoptosis in mcf‑7 cells through ros‑mediated mapk, stat3 and nf‑κb signaling pathways. |
2020-03-31 |
2023-08-13 |
human |
| Pei-Jun Chen, An-Quan Shang, Jian-Ping Yang, Wei-Wei Wan. microRNA-874 inhibition targeting STAT3 protects the heart from ischemia-reperfusion injury by attenuating cardiomyocyte apoptosis in a mouse model. Journal of cellular physiology. vol 234. issue 5. 2020-03-27. PMID:30370578. |
microrna-874 inhibition targeting stat3 protects the heart from ischemia-reperfusion injury by attenuating cardiomyocyte apoptosis in a mouse model. |
2020-03-27 |
2023-08-13 |
mouse |
| Pei-Jun Chen, An-Quan Shang, Jian-Ping Yang, Wei-Wei Wan. microRNA-874 inhibition targeting STAT3 protects the heart from ischemia-reperfusion injury by attenuating cardiomyocyte apoptosis in a mouse model. Journal of cellular physiology. vol 234. issue 5. 2020-03-27. PMID:30370578. |
terminal deoxynucleotidyl transferase (tdt)-mediated dutp biotin nick-end labeling (tunel) staining was used to detect cardiomyocyte apoptosis and dual luciferase reporter gene assay to identify the targeting relationship between mir-874 and stat3. |
2020-03-27 |
2023-08-13 |
mouse |
| Shengli Li, Song Yang, Bin Sun, Chunhua Han. Melatonin attenuates early brain injury after subarachnoid hemorrhage by the JAK-STAT signaling pathway. International journal of clinical and experimental pathology. vol 12. issue 3. 2020-03-25. PMID:31933900. |
mortality, neurological scores, brain edema, cell apoptosis, and the expression of jak1, stat3, and cleaved caspase-3 proteins were assayed after 24 h sah. |
2020-03-25 |
2023-08-13 |
rat |
| Jinghua Jiao, Yuheng Wang, Xiaofeng Sun, Xiaojing Jian. Midazolam induces A549 cell apoptosis International journal of clinical and experimental pathology. vol 11. issue 3. 2020-03-25. PMID:31938232. |
thus, midazolam can induce apoptosis of a549 cells by targeting stat3 via mir-520d-5p. |
2020-03-25 |
2023-08-13 |
Not clear |
| Shaoqing Lei, Wating Su, Zhong-Yuan Xia, Yafeng Wang, Lu Zhou, Shigang Qiao, Bo Zhao, Zhengyuan Xia, Michael G Irwi. Hyperglycemia-Induced Oxidative Stress Abrogates Remifentanil Preconditioning-Mediated Cardioprotection in Diabetic Rats by Impairing Caveolin-3-Modulated PI3K/Akt and JAK2/STAT3 Signaling. Oxidative medicine and cellular longevity. vol 2019. 2020-03-20. PMID:31583053. |
rpc significantly attenuated postischemic infarction, cardiac dysfunction, myocardial apoptosis, and 15-f2t-isoprostane production (a specific marker of oxidative stress), accompanied with increased cav-3 expression and enhanced akt and stat3 activation in control but not in diabetic rats. |
2020-03-20 |
2023-08-13 |
rat |
| Hao Tan, Xiang Li, Wei Han Yang, Yong Kan. A flavone, Wogonin from Scutellaria baicalensis inhibits the proliferation of human colorectal cancer cells by inducing of autophagy, apoptosis and G2/M cell cycle arrest via modulating the PI3K/AKT and STAT3 signalling pathways. Journal of B.U.ON. : official journal of the Balkan Union of Oncology. vol 24. issue 3. 2020-03-17. PMID:31424673. |
a flavone, wogonin from scutellaria baicalensis inhibits the proliferation of human colorectal cancer cells by inducing of autophagy, apoptosis and g2/m cell cycle arrest via modulating the pi3k/akt and stat3 signalling pathways. |
2020-03-17 |
2023-08-13 |
human |
| Qianqian Zhang, Hong Sun, Shougang Zhuang, Na Liu, Xiaowei Bao, Xiandong Liu, Huijuan Ren, Diyu Lv, Zhe Li, Jianwen Bai, Xiaohui Zhou, Lunxian Tan. Novel pharmacological inhibition of EZH2 attenuates septic shock by altering innate inflammatory responses to sepsis. International immunopharmacology. vol 76. 2020-03-17. PMID:31518916. |
blockage of ezh2 also suppressed the progression of lung injury and alleviated inflammation by decreasing the pulmonary cell apoptosis, reducing inflammatory cells infiltration and cytokines release through inhibition of the stat3 signaling pathway and recovery of pparγ activation. |
2020-03-17 |
2023-08-13 |
mouse |
| Yi Zhang, Ying-Hua Luo, Xian-Ji Piao, Gui-Nan Shen, Jia-Ru Wang, Yu-Chao Feng, Jin-Qian Li, Wan-Ting Xu, Yu Zhang, Tong Zhang, Chang-Yuan Wang, Cheng-Hao Ji. The design of 1,4-naphthoquinone derivatives and mechanisms underlying apoptosis induction through ROS-dependent MAPK/Akt/STAT3 pathways in human lung cancer cells. Bioorganic & medicinal chemistry. vol 27. issue 8. 2020-03-12. PMID:30846406. |
in addition, they induced the apoptosis of a549 lung cancer cells by increasing the phosphorylation of p38 and c-jun n-terminal kinase (p-jnk), and decreasing the phosphorylation of extracellular signal-related kinase (p-erk), protein kinase b (akt), and signal transducer and activator of transcription 3 (stat3). |
2020-03-12 |
2023-08-13 |
human |
| Yi Zhang, Ying-Hua Luo, Xian-Ji Piao, Gui-Nan Shen, Jia-Ru Wang, Yu-Chao Feng, Jin-Qian Li, Wan-Ting Xu, Yu Zhang, Tong Zhang, Chang-Yuan Wang, Cheng-Hao Ji. The design of 1,4-naphthoquinone derivatives and mechanisms underlying apoptosis induction through ROS-dependent MAPK/Akt/STAT3 pathways in human lung cancer cells. Bioorganic & medicinal chemistry. vol 27. issue 8. 2020-03-12. PMID:30846406. |
in conclusion, epdmnq and endmnq induced g1 phase cell cycle arrest and apoptosis in a549 cells via the ros-mediated activation of mitogen activated protein kinase (mapk), akt and stat3 signaling pathways. |
2020-03-12 |
2023-08-13 |
human |
| Xiao Huang, Mengru Cao, Shuhong Wu, Li Wang, Jing Hu, Reza J Mehran, Jack A Roth, Stephen G Swisher, Rui-Yu Wang, Hagop M Kantarjian, Michael Andreeff, Xiaoping Sun, Bingliang Fan. Anti-leukemia activity of NSC-743380 in SULT1A1-expressing acute myeloid leukemia cells is associated with inhibitions of cFLIP expression and PI3K/AKT/mTOR activities. Oncotarget. vol 8. issue 60. 2020-03-09. PMID:29254232. |
our recent study showed that acute myeloid leukemia (aml) cells expressing sult1a1 are highly sensitive to nsc-743380, a small molecule that inhibits stat3 activity and induces sult1a1-dependent apoptosis of various cancer cell lines. |
2020-03-09 |
2023-08-13 |
Not clear |
| Ning Li, Dong Mao, Yansha Cao, Hua Li, Fu Ren, Keyan L. Downregulation of SIRT6 by miR-34c-5p is associated with poor prognosis and promotes colon cancer proliferation through inhibiting apoptosis via the JAK2/STAT3 signaling pathway. International journal of oncology. vol 52. issue 5. 2020-03-06. PMID:29512698. |
the proliferation and apoptotic assays demonstrated that sirt6 was able to suppress colon cancer cell proliferation and induce apoptosis via the janus kinase 2 (jak2)/signal transducer and activator of transcription 3 (stat3) signaling pathway. |
2020-03-06 |
2023-08-13 |
Not clear |
| Pikun Cao, Bin Liu, Feng Du, Dong Li, Yongzheng Wang, Xiaoyan Yan, Xiao Li, Yuliang L. Scutellarin suppresses proliferation and promotes apoptosis in A549 lung adenocarcinoma cells via AKT/mTOR/4EBP1 and STAT3 pathways. Thoracic cancer. vol 10. issue 3. 2020-03-04. PMID:30666790. |
scutellarin suppresses proliferation and promotes apoptosis in a549 lung adenocarcinoma cells via akt/mtor/4ebp1 and stat3 pathways. |
2020-03-04 |
2023-08-13 |
Not clear |
| Shuli Yang, Lihui Si, Yan Jia, Wenwen Jian, Qing Yu, Min Wang, Ruixin Li. Kaempferol exerts anti-proliferative effects on human ovarian cancer cells by inducing apoptosis, G0/G1 cell cycle arrest and modulation of MEK/ERK and STAT3 pathways. Journal of B.U.ON. : official journal of the Balkan Union of Oncology. vol 24. issue 3. 2020-03-02. PMID:31424650. |
kaempferol exerts anti-proliferative effects on human ovarian cancer cells by inducing apoptosis, g0/g1 cell cycle arrest and modulation of mek/erk and stat3 pathways. |
2020-03-02 |
2023-08-13 |
human |
| Hongyi Li, Yanping Qian, Xi Wang, Ruyu Pi, Xia Zhao, Xiawei We. Targeted activation of Stat3 in combination with paclitaxel results in increased apoptosis in epithelial ovarian cancer cells and a reduced tumour burden. Cell proliferation. vol 53. issue 1. 2020-02-25. PMID:31778258. |
targeted activation of stat3 in combination with paclitaxel results in increased apoptosis in epithelial ovarian cancer cells and a reduced tumour burden. |
2020-02-25 |
2023-08-13 |
Not clear |