| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sue Chin Lee, Kuan-Hung Lin, Andrea Balogh, Derek D Norman, Mitul Bavaria, Bryan Kuo, Junming Yue, Louisa Balázs, Zoltán Benyó, Gábor Tigy. Dysregulation of lysophospholipid signaling by p53 in malignant cells and the tumor microenvironment. Cellular signalling. vol 78. 2021-06-01. PMID:33253914. |
in this review, we will provide an account on the seminal contributions of prof. lina obeid, who deciphered the crosstalk between p53 and the sphingolipid pathway particularly in modulating dna damage repair and apoptosis in non-transformed as well as transformed cells. |
2021-06-01 |
2023-08-13 |
human |
| Chaoqun Wang, Quan Xie, Wen Sun, Ying Zhou, Yu Li. lncRNA WT1-AS is upregulated in osteoporosis and regulates the apoptosis of osteoblasts by interacting with p53. Experimental and therapeutic medicine. vol 22. issue 1. 2021-06-01. PMID:34055051. |
lncrna wt1-as is upregulated in osteoporosis and regulates the apoptosis of osteoblasts by interacting with p53. |
2021-06-01 |
2023-08-13 |
Not clear |
| Chaoqun Wang, Quan Xie, Wen Sun, Ying Zhou, Yu Li. lncRNA WT1-AS is upregulated in osteoporosis and regulates the apoptosis of osteoblasts by interacting with p53. Experimental and therapeutic medicine. vol 22. issue 1. 2021-06-01. PMID:34055051. |
p53 overexpression attenuated the effects of wt1-as sirna silencing on cell apoptosis. |
2021-06-01 |
2023-08-13 |
Not clear |
| Chaoqun Wang, Quan Xie, Wen Sun, Ying Zhou, Yu Li. lncRNA WT1-AS is upregulated in osteoporosis and regulates the apoptosis of osteoblasts by interacting with p53. Experimental and therapeutic medicine. vol 22. issue 1. 2021-06-01. PMID:34055051. |
therefore, wt1-as was upregulated during osteoporosis and regulated the apoptosis of osteoblasts by interacting with p53. |
2021-06-01 |
2023-08-13 |
Not clear |
| Yongshan Cheng, Shanying Wu, Xinting Tie, Xiaodong Huang, Lihua Cu. Growth Inhibition of Nasopharyngeal Carcinoma Cells Mediated by p53 Gene-Containing Nanolipid Composites. Journal of nanoscience and nanotechnology. vol 20. issue 10. 2021-05-31. PMID:32384948. |
through the investigation of apoptosis and cell cycle changes in cne1 cells we found that the nanoliposome-encapsulated p53 gene can inhibit growth in these cells, and might therefore serve as a novel treatment strategy for adjuvant treatment of nasopharyngeal carcinoma and ca also reduce incompatibility issues with radiotherapy and chemotherapy. |
2021-05-31 |
2023-08-13 |
Not clear |
| Jie Li, Lijuan Long, Yiyang Zou, Si Zhan. Microbial community and transcriptional responses to increased temperatures in coral Pocillopora damicornis holobiont. Environmental microbiology. vol 23. issue 2. 2021-05-31. PMID:32686311. |
furthermore, apoptosis in p. damicornis is presumably induced through tumour necrosis factor and p53 signalling and caspase pathways. |
2021-05-31 |
2023-08-13 |
Not clear |
| Masahiro Nishimura, Yasuhiro Arimura, Kayo Nozawa, Hitoshi Kurumizak. Linker DNA and histone contributions in nucleosome binding by p53. Journal of biochemistry. vol 168. issue 6. 2021-05-31. PMID:32702132. |
the tumour suppressor protein p53 regulates various genes involved in cell-cycle arrest, apoptosis and dna repair in response to cellular stress, and apparently functions as a pioneer transcription factor. |
2021-05-31 |
2023-08-13 |
Not clear |
| Kathleen M Farmer, Gaurav Ghag, Nicha Puangmalai, Mauro Montalbano, Nemil Bhatt, Rakez Kaye. P53 aggregation, interactions with tau, and impaired DNA damage response in Alzheimer's disease. Acta neuropathologica communications. vol 8. issue 1. 2021-05-31. PMID:32778161. |
the transcription factor, p53, is critical for many important cellular functions involved in genome integrity, including cell cycle control, dna damage response, and apoptosis. |
2021-05-31 |
2023-08-13 |
mouse |
| Shailendra Anoopkumar-Dukie, Tom Conere, Aileen Houston, Liam King, David Christie, Catherine McDermott, Ashley Allshir. The COX-2 inhibitor NS398 selectively sensitizes hypoxic HeLa cells to ionising radiation by mechanisms both dependent and independent of COX-2. Prostaglandins & other lipid mediators. vol 148. 2021-05-28. PMID:32004752. |
we also show that ionising radiation at 5 gy results in phosphorylation of p53 at serine 15, a key phosphorylation site for p53-mediated apoptosis, and that hypoxia attenuates this phosphorylation. |
2021-05-28 |
2023-08-13 |
Not clear |
| Anil K Shendge, Sourav Panja, Tapasree Basu, Nripendranath Manda. A Tropical Lichen, Dirinaria consimilis Selectively Induces Apoptosis in MCF-7 Cells through the Regulation of p53 and Caspase-Cascade Pathway. Anti-cancer agents in medicinal chemistry. vol 20. issue 10. 2021-05-28. PMID:32188391. |
a tropical lichen, dirinaria consimilis selectively induces apoptosis in mcf-7 cells through the regulation of p53 and caspase-cascade pathway. |
2021-05-28 |
2023-08-13 |
Not clear |
| Xiang Li, Liangchun Ni, Weixin Wang, Liang Zong, Bi Ya. LncRNA Fendrr inhibits hypoxia/reoxygenation-induced cardiomyocyte apoptosis by downregulating p53 expression. The Journal of pharmacy and pharmacology. vol 72. issue 9. 2021-05-28. PMID:32537758. |
lncrna fendrr inhibits hypoxia/reoxygenation-induced cardiomyocyte apoptosis by downregulating p53 expression. |
2021-05-28 |
2023-08-13 |
Not clear |
| Xiang Li, Liangchun Ni, Weixin Wang, Liang Zong, Bi Ya. LncRNA Fendrr inhibits hypoxia/reoxygenation-induced cardiomyocyte apoptosis by downregulating p53 expression. The Journal of pharmacy and pharmacology. vol 72. issue 9. 2021-05-28. PMID:32537758. |
p53 has been shown to be an important regulator of apoptosis and is involved in myocardial i/r-induced apoptosis. |
2021-05-28 |
2023-08-13 |
Not clear |
| Xiang Li, Liangchun Ni, Weixin Wang, Liang Zong, Bi Ya. LncRNA Fendrr inhibits hypoxia/reoxygenation-induced cardiomyocyte apoptosis by downregulating p53 expression. The Journal of pharmacy and pharmacology. vol 72. issue 9. 2021-05-28. PMID:32537758. |
this study aims at investigating whether fendrr affects hypoxia/reoxygenation (h/r)-induced cardiomyocyte apoptosis through p53. |
2021-05-28 |
2023-08-13 |
Not clear |
| Amr Ahmed El-Arabey, Mohnad Abdalla, Adel Rashad Abd-Alla. SnapShot: TP53 status and macrophages infiltration in TCGA-analyzed tumors. International immunopharmacology. vol 86. 2021-05-27. PMID:32663767. |
tumor protein p53(tp53) plays a role in the regulation or progression of dna damage and repair through multiple mechanisms of the cell cycle, apoptosis, and genomic stability. |
2021-05-27 |
2023-08-13 |
Not clear |
| Junke Wang, Tianxin Zhao, Jiadong Chen, Lian Kang, Yuexin Wei, Yuhao Wu, Lindong Han, Lianju Shen, Chunlan Long, Shengde Wu, Guanghui We. Multiple transcriptomic profiling: p53 signaling pathway is involved in DEHP-induced prepubertal testicular injury via promoting cell apoptosis and inhibiting cell proliferation of Leydig cells. Journal of hazardous materials. vol 406. 2021-05-27. PMID:33162236. |
multiple transcriptomic profiling: p53 signaling pathway is involved in dehp-induced prepubertal testicular injury via promoting cell apoptosis and inhibiting cell proliferation of leydig cells. |
2021-05-27 |
2023-08-13 |
mouse |
| Junke Wang, Tianxin Zhao, Jiadong Chen, Lian Kang, Yuexin Wei, Yuhao Wu, Lindong Han, Lianju Shen, Chunlan Long, Shengde Wu, Guanghui We. Multiple transcriptomic profiling: p53 signaling pathway is involved in DEHP-induced prepubertal testicular injury via promoting cell apoptosis and inhibiting cell proliferation of Leydig cells. Journal of hazardous materials. vol 406. 2021-05-27. PMID:33162236. |
cumulatively, these findings revealed the involvement of the p53 signaling pathway in dehp-induced prepubertal testicular injury by promoting cell apoptosis and inhibiting cell proliferation of leydig cells. |
2021-05-27 |
2023-08-13 |
mouse |
| Ming Xu, Jing Zhu, Shuiping Liu, Chan Wang, Qinglan Shi, Yeye Kuang, Xiao Fang, Xiaotong H. FOXD3, frequently methylated in colorectal cancer, acts as a tumor suppressor and induces tumor cell apoptosis under ER stress via p53. Carcinogenesis. vol 41. issue 9. 2021-05-26. PMID:31784734. |
foxd3, frequently methylated in colorectal cancer, acts as a tumor suppressor and induces tumor cell apoptosis under er stress via p53. |
2021-05-26 |
2023-08-13 |
Not clear |
| Ming Xu, Jing Zhu, Shuiping Liu, Chan Wang, Qinglan Shi, Yeye Kuang, Xiao Fang, Xiaotong H. FOXD3, frequently methylated in colorectal cancer, acts as a tumor suppressor and induces tumor cell apoptosis under ER stress via p53. Carcinogenesis. vol 41. issue 9. 2021-05-26. PMID:31784734. |
knockdown of p53 impaired the effect of apoptosis induced by foxd3. |
2021-05-26 |
2023-08-13 |
Not clear |
| Ming Xu, Jing Zhu, Shuiping Liu, Chan Wang, Qinglan Shi, Yeye Kuang, Xiao Fang, Xiaotong H. FOXD3, frequently methylated in colorectal cancer, acts as a tumor suppressor and induces tumor cell apoptosis under ER stress via p53. Carcinogenesis. vol 41. issue 9. 2021-05-26. PMID:31784734. |
in conclusion, we showed for the first time that foxd3, which is frequently methylated in crc, acted as a tumor suppressor inducing tumor cell apoptosis under er stress via p53. |
2021-05-26 |
2023-08-13 |
Not clear |
| Jiahua Zhang, Yubang Shen, Xiaoyan Xu, Yafan Dai, Jiale L. Transcriptome Analysis of the Liver and Muscle Tissues of Black Carp (Mylopharyngodon piceus) of Different Growth Rates. Marine biotechnology (New York, N.Y.). vol 22. issue 5. 2021-05-26. PMID:32914204. |
the kegg pathway analysis showed significant differences in the expression of some genes involved in growth- and development-related metabolic pathways such as the foxo signaling pathway, p53 signaling pathway, pi3k-akt signaling pathway, apoptosis, tgf-β signaling pathway, and insulin signaling pathway. |
2021-05-26 |
2023-08-13 |
Not clear |