| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Timur Yagudin, Yue Zhao, Haiyu Gao, Yang Zhang, Ying Yang, Xiaofang Zhang, Wenbo Ma, Tolessa Muleta Daba, Vladimir Ishmetov, Kai Kang, Baofeng Yang, Zhenwei Pa. iASPP protects the heart from ischemia injury by inhibiting p53 expression and cardiomyocyte apoptosis. Acta biochimica et biophysica Sinica. vol 53. issue 1. 2021-06-17. PMID:33128543. |
mechanistically, overexpression of iaspp inhibited, while knockdown of iaspp increased the expressions of p53 and bax, the key regulators of apoptosis. |
2021-06-17 |
2023-08-13 |
mouse |
| Chawalit Chatupheeraphat, Sittiruk Roytrakul, Narumon Phaonakrop, Kamolchanok Deesrisak, Sucheewin Krobthong, Usanarat Anurathapan, Dalina Tanyon. A Novel Peptide Derived from Ginger Induces Apoptosis through the Modulation of p53, BAX, and BCL2 Expression in Leukemic Cell Lines. Planta medica. vol 87. issue 7. 2021-06-17. PMID:33757145. |
a novel peptide derived from ginger induces apoptosis through the modulation of p53, bax, and bcl2 expression in leukemic cell lines. |
2021-06-17 |
2023-08-13 |
Not clear |
| Gustavo Martínez-Noël, Valdimara Corrêa Vieira, Patricia Szajner, Erin M Lilienthal, Rebecca E Kramer, Kathleen A Boyland, Jennifer A Smith, Peter M Howle. Live cell, image-based high-throughput screen to quantitate p53 stabilization and viability in human papillomavirus positive cancer cells. Virology. vol 560. 2021-06-17. PMID:34051479. |
since p53 is generally wildtype in hrhpv-associated cancers, p53 stabilization arrests proliferation, induces apoptosis and/or results in senescence. |
2021-06-17 |
2023-08-13 |
human |
| Mohammad Javad Mousavi, Elham Farhadi, Mohammad Vodjgani, Jafar Karami, Mohammad Naghi Tahmasebi, Arash Sharafat Vaziri, Marzieh Asgari, Nima Rezaei, Shayan Mostafaei, Ahmadreza Jamshidi, Mahdi Mahmoud. Role of Fibroblast Activation Protein Alpha in Fibroblast-like Synoviocytes of Rheumatoid Arthritis. Iranian journal of allergy, asthma, and immunology. vol 20. issue 3. 2021-06-17. PMID:34134455. |
flss were divided into un-treated and talabostat-treated groups to evaluate the fap-α effect on the selected genes involved in cell cycle regulation (p21, p53, ccnd1), apoptosis (bcl-2, puma), and inflammatory and destructive behavior of flss (il-6, tgf-β1, mmp-2, mmp-9, p2rx7). |
2021-06-17 |
2023-08-13 |
Not clear |
| Matthew D Galbraith, Zdenek Andrysik, Kelly D Sullivan, Joaquín M Espinos. Global Analyses to Identify Direct Transcriptional Targets of p53. Methods in molecular biology (Clifton, N.J.). vol 2267. 2021-06-16. PMID:33786783. |
the transcription factor p53 controls a gene expression program with pleiotropic effects on cell biology including cell cycle arrest and apoptosis. |
2021-06-16 |
2023-08-13 |
Not clear |
| Lois Resnick-Silverma. Using TUNEL Assay to Quantitate p53-Induced Apoptosis in Mouse Tissues. Methods in molecular biology (Clifton, N.J.). vol 2267. 2021-06-16. PMID:33786792. |
p53, fulfills its role as "guardian of the genome" by either arresting cells in the cell cycle in order to allow time for repair of dna damage or regulating a process of programmed cell death known as apoptosis. |
2021-06-16 |
2023-08-13 |
mouse |
| Valentina V Nenasheva, Irina V Makarova, Ekaterina A Stepanenko, Stanislav A Antonov, Ekaterina V Novosadova, Anastasia R Narsullaeva, Larisa V Kozikova, Ekaterina A Polteva, Lyudmila A Sleptsova, Natalya A Shcherbatova, Nella V Khaidarova, Lyudmila E Andreeva, Vyacheslav Z Tarantu. Human TAF-Iα promotes oncogenic transformation via enhancement of cell proliferation and suppression of apoptosis. In vitro cellular & developmental biology. Animal. vol 57. issue 5. 2021-06-16. PMID:34021475. |
tunel assay as well as downregulation of p53 gene and upregulation of bcl-2 gene in these transgenic loaches demonstrated that both isoforms suppressed apoptosis. |
2021-06-16 |
2023-08-13 |
human |
| Nour N Al Zouabi, Cai M Roberts, Z Ping Lin, Elena S Ratne. Flow Cytometric Analyses of p53-Mediated Cell Cycle Arrest and Apoptosis in Cancer Cells. Methods in molecular biology (Clifton, N.J.). vol 2255. 2021-06-16. PMID:34033093. |
p53 functions as a tumor suppressor by inducing cell cycle arrest and apoptosis in response to genotoxic and environmental insults. |
2021-06-16 |
2023-08-13 |
Not clear |
| Nour N Al Zouabi, Cai M Roberts, Z Ping Lin, Elena S Ratne. Flow Cytometric Analyses of p53-Mediated Cell Cycle Arrest and Apoptosis in Cancer Cells. Methods in molecular biology (Clifton, N.J.). vol 2255. 2021-06-16. PMID:34033093. |
this chapter describes a method of flow cytometric analysis of ectopic expression of p53 to better quantify cell cycle distribution and apoptosis in cells treated with dna damaging agents. |
2021-06-16 |
2023-08-13 |
Not clear |
| Javed Ahmad, Rizwan Wahab, Maqsood A Siddiqui, Quaiser Saquib, Naushad Ahmad, Abdulaziz A Al-Khedhair. Strontium-Doped Nickel Oxide Nanoparticles: Synthesis, Characterization, and Cytotoxicity Study in Human Lung Cancer A549 Cells. Biological trace element research. 2021-06-16. PMID:34131861. |
as a result, apoptosis was mediated by the p53, bax, caspase3, and bcl-2 pathways, implying a potential mechanism by which srnionps mediate their toxicity. |
2021-06-16 |
2023-08-13 |
human |
| Chawalit Chatupheeraphat, Sittiruk Roytrakul, Narumon Phaonakrop, Kamolchanok Deesrisak, Sucheewin Krobthong, Usanarat Anurathapan, Dalina Tanyon. Correction: A Novel Peptide Derived from Ginger Induces Apoptosis through the Modulation of p53, BAX, and BCL2 Expression in Leukemic Cell Lines. Planta medica. 2021-06-15. PMID:33784770. |
correction: a novel peptide derived from ginger induces apoptosis through the modulation of p53, bax, and bcl2 expression in leukemic cell lines. |
2021-06-15 |
2023-08-13 |
Not clear |
| Tomas Venit, Khairunnisa Semesta, Sannia Farrukh, Martin Endara-Coll, Robert Havalda, Pavel Hozak, Piergiorgio Percipall. Nuclear myosin 1 activates p21 gene transcription in response to DNA damage through a chromatin-based mechanism. Communications biology. vol 3. issue 1. 2021-06-14. PMID:32161327. |
nm1 ko cells exhibit increased dna damage and changes in cell cycle progression, proliferation, and apoptosis, compatible with a phenotype resulting from impaired p53 signaling. |
2021-06-14 |
2023-08-13 |
mouse |
| Leijun Ye, Zhuoqing Song, Chunhe L. Landscape and flux quantify the stochastic transition dynamics for p53 cell fate decision. The Journal of chemical physics. vol 154. issue 2. 2021-06-14. PMID:33445890. |
the p53 transcription factor is a key mediator in cellular responses to various stress signals including dna repair, cell cycle arrest, and apoptosis. |
2021-06-14 |
2023-08-13 |
Not clear |
| Leijun Ye, Zhuoqing Song, Chunhe L. Landscape and flux quantify the stochastic transition dynamics for p53 cell fate decision. The Journal of chemical physics. vol 154. issue 2. 2021-06-14. PMID:33445890. |
the landscape topography unifies and quantifies three cell fate states, including the limit cycle oscillations (representing cell cycle arrest), high p53 state (characterizing apoptosis), and low p53 state (characterizing the normal proliferative state). |
2021-06-14 |
2023-08-13 |
Not clear |
| Angelica Judith Granados-López, Eduardo Manzanares-Acuña, Yamilé López-Hernández, Julio Enrique Castañeda-Delgado, Ixamail Fraire-Soto, Claudia Araceli Reyes-Estrada, Rosalinda Gutiérrez-Hernández, Jesús Adrián Lópe. UVB Inhibits Proliferation, Cell Cycle and Induces Apoptosis via p53, E2F1 and Microtubules System in Cervical Cancer Cell Lines. International journal of molecular sciences. vol 22. issue 10. 2021-06-10. PMID:34068980. |
uvb inhibits proliferation, cell cycle and induces apoptosis via p53, e2f1 and microtubules system in cervical cancer cell lines. |
2021-06-10 |
2023-08-13 |
Not clear |
| Pragalathan Naidoo, Rajen N Naidoo, Prithiksha Ramkaran, Anil A Chuturgoo. Effect of maternal HIV infection, BMI and NOx air pollution exposure on birth outcomes in South African pregnant women genotyped for the p53 Pro72Arg (rs1042522). International journal of immunogenetics. vol 47. issue 5. 2021-06-09. PMID:32080966. |
tumour suppressor protein, p53, plays a role in modulating innate immune responses, dna repair, cell cycle arrest, senescence and apoptosis. |
2021-06-09 |
2023-08-13 |
human |
| Jessica Beck, Casmir Turnquist, Izumi Horikawa, Curtis Harri. Targeting cellular senescence in cancer and aging: roles of p53 and its isoforms. Carcinogenesis. vol 41. issue 8. 2021-06-09. PMID:32619002. |
these truncated p53 isoform proteins are endogenously expressed in normal human cells and maintain important functional roles, including modulation of full-length p53-mediated cellular senescence, apoptosis and dna repair. |
2021-06-09 |
2023-08-13 |
human |
| Shweta Singh, Hien Nguyen, David Michels, Hannah Bazinet, Pratiek N Matkar, Zongyi Liu, Lilian Esene, Mohamed Adam, Antoinette Bugyei-Twum, Elizabeth Mebrahtu, Jameela Joseph, Mehroz Ehsan, Hao H Chen, Mohammad Qadura, Krishna K Sing. BReast CAncer susceptibility gene 2 deficiency exacerbates oxidized LDL-induced DNA damage and endothelial apoptosis. Physiological reports. vol 8. issue 13. 2021-06-09. PMID:32638521. |
increased dsbs were associated with enhanced expression and activation of pro-apoptotic p53 and significant apoptosis in oxldl-treated brca2-silenced ecs. |
2021-06-09 |
2023-08-13 |
human |
| Yiqun Liu, Fangjuan Hu, Long Zha. Effect of Nano-Platinum on Proliferation and Apoptosis of Non-Small Cell Lung Cancer Cells via P53 Pathway. Journal of nanoscience and nanotechnology. vol 21. issue 2. 2021-06-09. PMID:33183422. |
effect of nano-platinum on proliferation and apoptosis of non-small cell lung cancer cells via p53 pathway. |
2021-06-09 |
2023-08-13 |
Not clear |
| Yiqun Liu, Fangjuan Hu, Long Zha. Effect of Nano-Platinum on Proliferation and Apoptosis of Non-Small Cell Lung Cancer Cells via P53 Pathway. Journal of nanoscience and nanotechnology. vol 21. issue 2. 2021-06-09. PMID:33183422. |
the relationship between the inhibition of non-small cell lung cancer cell proliferation, apoptosis, and the expression of its related apoptotic protein p53. |
2021-06-09 |
2023-08-13 |
Not clear |