| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Se-Mi Oh, Jinhee Kim, Jun Lee, Jin-Mu Yi, Dal-Seok Oh, Ok-Sun Bang, No Soo Ki. Anticancer potential of an ethanol extract of Asiasari radix against HCT-116 human colon cancer cells in vitro. Oncology letters. vol 5. issue 1. 2021-10-21. PMID:23255939. |
taken together, these results suggest that eear inhibits the growth of the hct-116 cells through induction of g2/m cell cycle arrest and apoptosis, which are mediated by p53 expression. |
2021-10-21 |
2023-08-12 |
human |
| Kaishan Liu, Xiaomei Zhuang, Zhuoying Ma. p73 expression is associated with cellular chemosensitivity in human non-small cell lung cancer cell lines. Oncology letters. vol 5. issue 2. 2021-10-21. PMID:23420689. |
p73 is a member of the p53 tumor suppressor protein family and induces apoptosis in tumor cells that lack functional p53. |
2021-10-21 |
2023-08-12 |
human |
| Jonathan F Arambula, Jonathan L Sessler, Zahid H Siddi. A texaphyrin-oxaliplatin conjugate that overcomes both pharmacologic and molecular mechanisms of cisplatin resistance in cancer cells. MedChemComm. vol 3. issue 10. 2021-10-21. PMID:23936624. |
unlike cisplatin, oxalitex accumulated and formed dna adducts, stabilized and activated p53 at similar levels in both sensitive and resistant cells, and induced apoptosis in both models. |
2021-10-21 |
2023-08-12 |
Not clear |
| Manunya Nuth, Ann R Kenned. Mitigating effects of L-selenomethionine on low-dose iron ion radiation-induced changes in gene expression associated with cellular stress. Oncology letters. vol 6. issue 1. 2021-10-21. PMID:23946774. |
even at low doses of radiation from iron ions, global genome profiling of the irradiated cells revealed the upregulation of genes associated with the activation of stress-related signaling pathways (ubiquitin-mediated proteolysis, p53 signaling, cell cycle and apoptosis), which occurred in a dose-dependent manner. |
2021-10-21 |
2023-08-12 |
human |
| Chunyan Li, Lin Wang, Jing Su, Ruhui Zhang, Li Fu, Yanmin Zho. mRNA expression and hypermethylation of tumor suppressor genes apoptosis protease activating factor-1 and death-associated protein kinase in oral squamous cell carcinoma. Oncology letters. vol 6. issue 1. 2021-10-21. PMID:23946818. |
apoptosis protease activating factor-1 (apaf-1) and death-associated protein kinase (dapk) are p53 pathway-related genes that play significant roles in the activation of caspases, which are involved in mitochondrial-mediated apoptosis. |
2021-10-21 |
2023-08-12 |
human |
| Sevil Oskay Halacli, Hande Canpinar, Eren Cimen, Asuman Sungurogl. Effects of gamma irradiation on cell cycle, apoptosis and telomerase activity in p53 wild-type and deficient HCT116 colon cancer cell lines. Oncology letters. vol 6. issue 3. 2021-10-21. PMID:24137415. |
effects of gamma irradiation on cell cycle, apoptosis and telomerase activity in p53 wild-type and deficient hct116 colon cancer cell lines. |
2021-10-21 |
2023-08-12 |
Not clear |
| Sevil Oskay Halacli, Hande Canpinar, Eren Cimen, Asuman Sungurogl. Effects of gamma irradiation on cell cycle, apoptosis and telomerase activity in p53 wild-type and deficient HCT116 colon cancer cell lines. Oncology letters. vol 6. issue 3. 2021-10-21. PMID:24137415. |
however, the cellular response to irradiation varies depending on the expression of tumor suppressor p53, which plays a significant role in the regulation of cell cycle arrest, apoptosis and telomerase activity in various cancers. |
2021-10-21 |
2023-08-12 |
Not clear |
| Sevil Oskay Halacli, Hande Canpinar, Eren Cimen, Asuman Sungurogl. Effects of gamma irradiation on cell cycle, apoptosis and telomerase activity in p53 wild-type and deficient HCT116 colon cancer cell lines. Oncology letters. vol 6. issue 3. 2021-10-21. PMID:24137415. |
the present study aimed to investigate cell cycle arrest, apoptosis and telomerase activity with respect to p53 expression in p53 wild-type (+/+) and deficient (-/-) hct116 colon cancer cell lines following 5 gy γ-irradiation. |
2021-10-21 |
2023-08-12 |
Not clear |
| Song Yi Park, Chang Hee Jung, Bokyung Song, Ock Jin Park, Young-Min Ki. Pro-apoptotic and migration-suppressing potential of EGCG, and the involvement of AMPK in the p53-mediated modulation of VEGF and MMP-9 expression. Oncology letters. vol 6. issue 5. 2021-10-21. PMID:24179522. |
egcg treatment induced apoptosis in the presence of wild-type and mutant p53, indicating that a p53-independent pathway may contribute to egcg-induced apoptosis in these cells. |
2021-10-21 |
2023-08-12 |
Not clear |
| Zhong-Hai Zhao, LE Lin, A Liang, Hong-Qiu Li, Yue Zh. UNC5H4-induced apoptosis in non-small cell lung cancer is not dependent on p53 status only. Oncology letters. vol 6. issue 5. 2021-10-21. PMID:24179525. |
unc5h4-induced apoptosis in non-small cell lung cancer is not dependent on p53 status only. |
2021-10-21 |
2023-08-12 |
Not clear |
| Zhong-Hai Zhao, LE Lin, A Liang, Hong-Qiu Li, Yue Zh. UNC5H4-induced apoptosis in non-small cell lung cancer is not dependent on p53 status only. Oncology letters. vol 6. issue 5. 2021-10-21. PMID:24179525. |
unc5h4 and p53 expression levels were detected by immunohistochemistry, apoptosis was determined by a terminal deoxynucleotidyl transferase-mediated dutp nick end labeling assay and caspase 3 activation was determined by western blotting. |
2021-10-21 |
2023-08-12 |
Not clear |
| Zhong-Hai Zhao, LE Lin, A Liang, Hong-Qiu Li, Yue Zh. UNC5H4-induced apoptosis in non-small cell lung cancer is not dependent on p53 status only. Oncology letters. vol 6. issue 5. 2021-10-21. PMID:24179525. |
in conclusion, these results indicate that x-rays induce apoptosis via the p53 pathway, and when this pathway is compromised, an additional pathway is utilized. |
2021-10-21 |
2023-08-12 |
Not clear |
| Zong-Gang Xie, Ye Xie, Qi-Rong Don. Inhibition of the mammalian target of rapamycin leads to autophagy activation and cell death of MG63 osteosarcoma cells. Oncology letters. vol 6. issue 5. 2021-10-21. PMID:24179542. |
western blot analysis was used to determine the expression of the proteins that are involved in apoptosis and autophagy, including p53, p62, light chain 3 (lc3) and beclin-1. |
2021-10-21 |
2023-08-12 |
Not clear |
| F L Jiang, S Leo, X G Wang, H Li, L Y Gong, Y Kuang, X F X. Effect of tanshinone IIA on cardiomyocyte hypertrophy and apoptosis in spontaneously hypertensive rats. Experimental and therapeutic medicine. vol 6. issue 6. 2021-10-21. PMID:24255684. |
evaluation of bcl-2, bax and p53 expression levels for apoptosis analysis was performed using western blotting. |
2021-10-21 |
2023-08-12 |
rat |
| F L Jiang, S Leo, X G Wang, H Li, L Y Gong, Y Kuang, X F X. Effect of tanshinone IIA on cardiomyocyte hypertrophy and apoptosis in spontaneously hypertensive rats. Experimental and therapeutic medicine. vol 6. issue 6. 2021-10-21. PMID:24255684. |
it was observed that the sbp, lvmi, cardiomyocyte size and diameter, cvf, pcva and cardiomyocyte apoptosis index (bax and p53 expression) were increased significantly in group s18 compared with group s8. |
2021-10-21 |
2023-08-12 |
rat |
| F L Jiang, S Leo, X G Wang, H Li, L Y Gong, Y Kuang, X F X. Effect of tanshinone IIA on cardiomyocyte hypertrophy and apoptosis in spontaneously hypertensive rats. Experimental and therapeutic medicine. vol 6. issue 6. 2021-10-21. PMID:24255684. |
tsn may inhibit the development of lvh and decrease the level of apoptosis in shrs, possibly via the upregulation of bcl-2 and the downregulation of bax and p53 expression. |
2021-10-21 |
2023-08-12 |
rat |
| Hirendra Nath Banerjee, Millon Blackshear, Jordan Williams, Zack Hawkins, Crystal Sawyer, Vinod Manglik, Shailendra Gir. C-6 Ceramide Induces p53 Dependent Apoptosis in Human Astrocytoma Grade4 (Glioblastoma Multiforme) Cells. Journal of cancer science & therapy. vol 4. issue 2. 2021-10-21. PMID:24319543. |
c-6 ceramide induces p53 dependent apoptosis in human astrocytoma grade4 (glioblastoma multiforme) cells. |
2021-10-21 |
2023-08-12 |
human |
| Peiyue Jiang, Ying Yu. Human papillomavirus oncoproteins and apoptosis (Review). Experimental and therapeutic medicine. vol 7. issue 1. 2021-10-21. PMID:24348754. |
e5 protein protects cells from tumor necrosis factor-associated apoptosis; the oncoprotein e6 predominantly inhibits apoptosis through the p53 pathway; and oncoprotein e7 is involved in apoptosis activation and inhibition. |
2021-10-21 |
2023-08-12 |
human |
| Dehua Wei, Qinghua Wu, Huirong Sh. Apoptosis and p53 expression in the placental villi of females with unexplained recurrent spontaneous abortion. Experimental and therapeutic medicine. vol 7. issue 1. 2021-10-21. PMID:24348788. |
apoptosis and p53 expression in the placental villi of females with unexplained recurrent spontaneous abortion. |
2021-10-21 |
2023-08-12 |
human |
| Dehua Wei, Qinghua Wu, Huirong Sh. Apoptosis and p53 expression in the placental villi of females with unexplained recurrent spontaneous abortion. Experimental and therapeutic medicine. vol 7. issue 1. 2021-10-21. PMID:24348788. |
the aim of this study was to explore the level of apoptosis and p53 expression in the placental villi of patients with unexplained recurrent spontaneous abortion (ursa). |
2021-10-21 |
2023-08-12 |
human |