| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Muhammad Arza Putra, Normalina Sandora, Suwarti, Retno Wahyu Nurhayati, Raisa Nauli, Tyas Rahmah Kusuma, Nur Amalina Fitria, Ardiansyah, Chaidar Muttaqin, William Makdinata, Idrus Alw. Transport viable heart tissue at physiological temperature yielded higher human cardiomyocytes compared to the conventional temperature. Cell and tissue banking. 2022-01-07. PMID:34993730. |
although the 37 °c group expressed the apoptosis genes such as p21, p53 and caspase9 by 2.5-, 5.41-, 5-fold respectively (p > 0.05). |
2022-01-07 |
2023-08-13 |
human |
| Nabil A Alhakamy, Mohammed W Al-Rabia, Hani Z Asfour, Samah Alshehri, Waleed S Alharbi, Abdulrahman Halawani, Abdulmohsin J Alamoudi, Ahmad O Noor, Douha F Bannan, Usama A Fahmy, Sabna Kott. 2-Methoxy-estradiol Loaded Alpha Lipoic Acid Nanoparticles Augment Cytotoxicity in MCF-7 Breast Cancer Cells. Dose-response : a publication of International Hormesis Society. vol 19. issue 4. 2022-01-06. PMID:34987331. |
this increased apoptosis was also associated with increased ros and increased p53 expression in 2me-ala nps treated cells compared to the raw-2 me group. |
2022-01-06 |
2023-08-13 |
Not clear |
| Jianhong Shi, Ruizhi Li, Yuanxiao Yang, Liting Ji, Changyu L. Protective effect of α-asarone and β-asarone on Aβ -induced inflammatory response in PC12 cells and its. Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences. vol 50. issue 5. 2022-01-05. PMID:34986541. |
the levels of inflammatory cytokines interleukin (il)-1, , tumor necrosis factor (tnf)-α, oxidation-related inducible nitric oxide synthase (inos), nitric oxide (no), apoptosis factors caspase-3 and p53 were detected by elisa method. |
2022-01-05 |
2023-08-13 |
Not clear |
| Jianhong Shi, Ruizhi Li, Yuanxiao Yang, Liting Ji, Changyu L. Protective effect of α-asarone and β-asarone on Aβ -induced inflammatory response in PC12 cells and its. Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences. vol 50. issue 5. 2022-01-05. PMID:34986541. |
compared with model control group, cell survival rates of group, β-asarone group and vip group increased; the cell apoptosis rate decreased; levels of apoptosis-related factors caspase-3, p53, inflammatory factors il-1, tnf-α decreased; il-10 level increased; levels of oxidization-related factors inos and no decreased; the expression of jnk and p38mapk protein decreased (all <0.05). |
2022-01-05 |
2023-08-13 |
Not clear |
| Jianhong Shi, Ruizhi Li, Yuanxiao Yang, Liting Ji, Changyu L. Protective effect of α-asarone and β-asarone on Aβ -induced inflammatory response in PC12 cells and its. Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences. vol 50. issue 5. 2022-01-05. PMID:34986541. |
after vip antagonist intervention, the survival rate of β-asarone group decreased; apoptosis rate increased; apoptosis related factors caspase-3, p53, inflammatory factors il-1, tnf-α increased; il-10 decreased; oxidation related factors inos and no increased; the expression of jnk and p38mapk protein increased (all <0.05); while there were no significant changes in these indicators of α-asarone group (all >0.05). |
2022-01-05 |
2023-08-13 |
Not clear |
| Wagner J Fávaro, Eduardo A R Socca, Petra K Böckelmann, Ianny B Reis, Patrick V Garcia, Nelson Durá. Impact of intravesical instillation of a novel biological response modifier (P-MAPA) on progress of non-muscle invasive bladder cancer treatment in a rat model. Medical oncology (Northwood, London, England). vol 39. issue 2. 2022-01-04. PMID:34982270. |
p-mapa intravesical treatment increased the wild-type p53 levels and enhanced c-myc/coup-tfii-induced apoptosis mediated by p53. |
2022-01-04 |
2023-08-13 |
rat |
| Feng Yun Yang, Lu Zhang, Yan Zheng, He Don. Dexmedetomidine attenuates ischemia and reperfusion-induced cardiomyocyte injury through p53 and forkhead box O3a (FOXO3a)/p53-upregulated modulator of apoptosis (PUMA) signaling signaling. Bioengineered. vol 13. issue 1. 2022-01-03. PMID:34974801. |
dexmedetomidine attenuates ischemia and reperfusion-induced cardiomyocyte injury through p53 and forkhead box o3a (foxo3a)/p53-upregulated modulator of apoptosis (puma) signaling signaling. |
2022-01-03 |
2023-08-13 |
mouse |
| Feng Yun Yang, Lu Zhang, Yan Zheng, He Don. Dexmedetomidine attenuates ischemia and reperfusion-induced cardiomyocyte injury through p53 and forkhead box O3a (FOXO3a)/p53-upregulated modulator of apoptosis (PUMA) signaling signaling. Bioengineered. vol 13. issue 1. 2022-01-03. PMID:34974801. |
in addition, h/r and i/r injury increased p53 expression and forkhead box o3a (foxo3a)/p53-upregulated modulator of apoptosis (puma) signaling in h9c2 cardiomyocyte cells and cardiomyocytes. |
2022-01-03 |
2023-08-13 |
mouse |
| Feng Yun Yang, Lu Zhang, Yan Zheng, He Don. Dexmedetomidine attenuates ischemia and reperfusion-induced cardiomyocyte injury through p53 and forkhead box O3a (FOXO3a)/p53-upregulated modulator of apoptosis (PUMA) signaling signaling. Bioengineered. vol 13. issue 1. 2022-01-03. PMID:34974801. |
targeting p53 expression or foxo3a/puma signaling inhibited cell apoptosis and protected against h/r injury in h9c2 cardiomyocyte cells and cardiomyocytes. |
2022-01-03 |
2023-08-13 |
mouse |
| Feng Yun Yang, Lu Zhang, Yan Zheng, He Don. Dexmedetomidine attenuates ischemia and reperfusion-induced cardiomyocyte injury through p53 and forkhead box O3a (FOXO3a)/p53-upregulated modulator of apoptosis (PUMA) signaling signaling. Bioengineered. vol 13. issue 1. 2022-01-03. PMID:34974801. |
pretreatment with dex reduced the h/r or i/r injury-induced activation of p53 expression and foxo3a/puma signaling, and alleviated h/r or i/r injury-induced apoptosis and mitochondrial oxidative stress. |
2022-01-03 |
2023-08-13 |
mouse |
| Feng Yun Yang, Lu Zhang, Yan Zheng, He Don. Dexmedetomidine attenuates ischemia and reperfusion-induced cardiomyocyte injury through p53 and forkhead box O3a (FOXO3a)/p53-upregulated modulator of apoptosis (PUMA) signaling signaling. Bioengineered. vol 13. issue 1. 2022-01-03. PMID:34974801. |
therefore, dex could alleviate h/r- or i/r-induced cardiomyocytes injury by reducing cell apoptosis and blocking p53 expression and foxo3a/puma signaling. |
2022-01-03 |
2023-08-13 |
mouse |
| Fan Yang, Runjia Fan, Miaomiao Gou, Qinna Yang, Tianlan Zhang, Guanghai Dai, Niansong Qia. Research on Mechanism of miR-214 Packaged with Lipidosome Nanoparticles on Prompting the Apoptosis of Intestinal Cancer Through Regulating p53 Pathway. Journal of biomedical nanotechnology. vol 17. issue 12. 2022-01-03. PMID:34974862. |
research on mechanism of mir-214 packaged with lipidosome nanoparticles on prompting the apoptosis of intestinal cancer through regulating p53 pathway. |
2022-01-03 |
2023-08-13 |
Not clear |
| Fan Yang, Runjia Fan, Miaomiao Gou, Qinna Yang, Tianlan Zhang, Guanghai Dai, Niansong Qia. Research on Mechanism of miR-214 Packaged with Lipidosome Nanoparticles on Prompting the Apoptosis of Intestinal Cancer Through Regulating p53 Pathway. Journal of biomedical nanotechnology. vol 17. issue 12. 2022-01-03. PMID:34974862. |
our study aimed at studying mechanism of mir-214 packaged with lipidosome nanoparticles on prompting apoptosis of intestinal cancer through regulating p53 pathway. |
2022-01-03 |
2023-08-13 |
Not clear |
| Fan Yang, Runjia Fan, Miaomiao Gou, Qinna Yang, Tianlan Zhang, Guanghai Dai, Niansong Qia. Research on Mechanism of miR-214 Packaged with Lipidosome Nanoparticles on Prompting the Apoptosis of Intestinal Cancer Through Regulating p53 Pathway. Journal of biomedical nanotechnology. vol 17. issue 12. 2022-01-03. PMID:34974862. |
the effect of mir-214 packaged with lipidosome nanoparticles on proliferation and apoptosis of intestinal cancer cells and p53 pathway in intestinal cancer cells was observed. |
2022-01-03 |
2023-08-13 |
Not clear |
| Gang Nan, Shu-Hua Zhao, Ting Wang, Dong Chao, Ruo-Fei Tian, Wen-Jing Wang, Xin Fu, Peng Lin, Ting Guo, Bin Wang, Xiu-Xuan Sun, Xi Chen, Zhi-Nan Chen, Shi-Jie Wang, Hong-Yong Cu. CD147 supports paclitaxel resistance via interacting with RanBP1. Oncogene. 2022-01-02. PMID:34974521. |
cd147 protected cancer cells from paclitaxel-induced caspase-3 mediated apoptosis regardless of p53 status. |
2022-01-02 |
2023-08-13 |
human |
| Norihisa Bizen, Asim K Bepari, Li Zhou, Manabu Abe, Kenji Sakimura, Katsuhiko Ono, Hirohide Takebayash. Ddx20, an Olig2 binding factor, governs the survival of neural and oligodendrocyte progenitor cells via proper Mdm2 splicing and p53 suppression. Cell death and differentiation. 2022-01-02. PMID:34974536. |
a central nervous system (cns)-specific ddx20 conditional knockout (cko) demonstrated apoptosis and cell cycle arrest in npcs and opcs, through the potentiation of the p53 pathway in dna damage-dependent and independent manners, including smn complex disruption and the abnormal splicing of mdm2 mrna. |
2022-01-02 |
2023-08-13 |
Not clear |
| Eduardo García-Garrido, Marco Cordani, Álvaro Somoz. Modified Gold Nanoparticles to Overcome the Chemoresistance to Gemcitabine in Mutant p53 Cancer Cells. Pharmaceutics. vol 13. issue 12. 2021-12-28. PMID:34959348. |
the nanostructures generated here provide a non-toxic and powerful system for the delivery of gapmers in cancer cells, which significantly downregulated mutant p53 proteins and altered molecular markers related to cell growth and apoptosis, thus overcoming chemoresistance to gemcitabine. |
2021-12-28 |
2023-08-13 |
human |
| Sara Vanessa Bernhard, Katarzyna Seget-Trzensiok, Christian Kuffer, Dragomir B Krastev, Lisa-Marie Stautmeister, Mirko Theis, Kristina Keuper, Jan-Eric Boekenkamp, Maik Kschischo, Frank Buchholz, Zuzana Storchov. Loss of USP28 and SPINT2 expression promotes cancer cell survival after whole genome doubling. Cellular oncology (Dordrecht). 2021-12-28. PMID:34962618. |
yet, erroneously arising human tetraploid cells usually do not proliferate due to p53 activation that leads to cdkn1a expression, cell cycle arrest, senescence and/or apoptosis. |
2021-12-28 |
2023-08-13 |
human |
| Tzitzijanik Madrigal, Jesús Hernández-Monge, Luis A Herrera, Claudia Haydée González-De la Rosa, Guadalupe Domínguez-Gómez, Myrna Candelaria, Fernando Luna-Maldonado, Karla G Calderón González, José Díaz-Cháve. Regulation of miRNAs Expression by Mutant p53 Gain of Function in Cancer. Frontiers in cell and developmental biology. vol 9. 2021-12-27. PMID:34957087. |
the p53 roles have been largely described; among them, cell proliferation and apoptosis control are some of the best studied and understood. |
2021-12-27 |
2023-08-13 |
Not clear |
| Jinwoo Kim, Dabin Ahn, Chin-Ju Par. Biophysical investigation of the dual binding surfaces of human transcription factors FOXO4 and p53. The FEBS journal. 2021-12-26. PMID:34954873. |
inhibition of the interaction is a strategy for inducing apoptosis of senescent cells, but the binding surfaces that mediate the foxo4- p53 interaction remain elusive. |
2021-12-26 |
2023-08-13 |
human |