| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yun-Hee Bae, Jong Hyo Ryu, Hyun-Joo Park, Kwang Rok Kim, Hee-Jun Wee, Ok-Hee Lee, Hye-Ock Jang, Moon-Kyoung Bae, Kyu-Won Kim, Soo-Kyung Ba. Mutant p53-Notch1 Signaling Axis Is Involved in Curcumin-Induced Apoptosis of Breast Cancer Cells. The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology. vol 17. issue 4. 2013-08-15. PMID:23946688. |
overexpression of mutant p53 increased notch1 promoter activity, whereas knockdown of mutant p53 by small interfering rna suppressed notch1 expression, leading to the induction of cellular apoptosis. |
2013-08-15 |
2023-08-12 |
human |
| Yun-Hee Bae, Jong Hyo Ryu, Hyun-Joo Park, Kwang Rok Kim, Hee-Jun Wee, Ok-Hee Lee, Hye-Ock Jang, Moon-Kyoung Bae, Kyu-Won Kim, Soo-Kyung Ba. Mutant p53-Notch1 Signaling Axis Is Involved in Curcumin-Induced Apoptosis of Breast Cancer Cells. The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology. vol 17. issue 4. 2013-08-15. PMID:23946688. |
moreover, curcumin-induced apoptosis was further enhanced by the knockdown of notch1 or mutant p53, but it was decreased by the overexpression of active notch1. |
2013-08-15 |
2023-08-12 |
human |
| Juliana Noguti, Tathiana Aparecida Alvarenga, Mônica Levy Andersen, Sergio Tufik, Celina Tijuko Fujiyama Oshima, Daniel Araki Ribeir. The influence of sleep deprivation on expression of apoptosis regulatory proteins p53, bcl-2 and bax following rat tongue carcinogenesis induced by 4-nitroquinoline 1-oxide. Dental research journal. vol 10. issue 2. 2013-08-15. PMID:23946744. |
the influence of sleep deprivation on expression of apoptosis regulatory proteins p53, bcl-2 and bax following rat tongue carcinogenesis induced by 4-nitroquinoline 1-oxide. |
2013-08-15 |
2023-08-12 |
rat |
| Melissa M Fox, Kathryn N Phoenix, Stavros G Kopsiaftis, Kevin P Claffe. AMP-Activated Protein Kinase α 2 Isoform Suppression in Primary Breast Cancer Alters AMPK Growth Control and Apoptotic Signaling. Genes & cancer. vol 4. issue 1-2. 2013-08-15. PMID:23946867. |
furthermore, ampkα2 xenografts exhibited diminished cyclin d1 levels along with an increased amount of nuclear p53, thereby implicating the ampkα2-p53 signaling axis as a mediator of cell apoptosis. |
2013-08-15 |
2023-08-12 |
human |
| Alexis Díaz-García, Luis Morier-Díaz, Yahima Frión-Herrera, Hermis Rodríguez-Sánchez, Yamira Caballero-Lorenzo, Dianeya Mendoza-Llanes, Yanelis Riquenes-Garlobo, José A Fraga-Castr. In vitro anticancer effect of venom from Cuban scorpion Rhopalurus junceus against a panel of human cancer cell lines. Journal of venom research. vol 4. 2013-08-15. PMID:23946884. |
scorpion venom demonstrated to induce apoptosis in less sensitive tumor cells (hela) as evidenced by chromatin condensation, over expression of p53 and bax mrna, down expression of bcl-2 mrna and increase of activated caspases 3, 8, 9. |
2013-08-15 |
2023-08-12 |
human |
| Shang-Jui Wang, Guowu Yu, Le Jiang, Tongyuan Li, Qing Lin, Yi Tang, Wei G. p53-Dependent regulation of metabolic function through transcriptional activation of pantothenate kinase-1 gene. Cell cycle (Georgetown, Tex.). vol 12. issue 5. 2013-08-14. PMID:23343762. |
it is well established that the p53 tumor suppressor plays a crucial role in controlling cell proliferation and apoptosis upon various types of stress. |
2013-08-14 |
2023-08-12 |
mouse |
| Shang-Jui Wang, Guowu Yu, Le Jiang, Tongyuan Li, Qing Lin, Yi Tang, Wei G. p53-Dependent regulation of metabolic function through transcriptional activation of pantothenate kinase-1 gene. Cell cycle (Georgetown, Tex.). vol 12. issue 5. 2013-08-14. PMID:23343762. |
although dna damage-induced p53 upregulates pank1 expression, depletion of pank1 expression does not affect p53-dependent growth arrest or apoptosis. |
2013-08-14 |
2023-08-12 |
mouse |
| Shang-Jui Wang, Guowu Yu, Le Jiang, Tongyuan Li, Qing Lin, Yi Tang, Wei G. p53-Dependent regulation of metabolic function through transcriptional activation of pantothenate kinase-1 gene. Cell cycle (Georgetown, Tex.). vol 12. issue 5. 2013-08-14. PMID:23343762. |
together, our findings show that p53 plays an important role in regulating energy homeostasis through transcriptional control of pank1, independent of its canonical functions in apoptosis and cell cycle arrest. |
2013-08-14 |
2023-08-12 |
mouse |
| Kristina Mitic, Mirjana Popovska, Maja Pandilova, Rubens Jovanovic, Goce Spasovski, Vladimir Nikolo. The role of inflammation and apoptosis in cyclosporine A-induced gingival overgrowth. Bosnian journal of basic medical sciences. vol 13. issue 1. 2013-08-14. PMID:23448605. |
the aim of our study was to detect the level of apoptosis, expression bcl-2 and p53, associated with the different doses of csa. |
2013-08-14 |
2023-08-12 |
Not clear |
| Kristina Mitic, Mirjana Popovska, Maja Pandilova, Rubens Jovanovic, Goce Spasovski, Vladimir Nikolo. The role of inflammation and apoptosis in cyclosporine A-induced gingival overgrowth. Bosnian journal of basic medical sciences. vol 13. issue 1. 2013-08-14. PMID:23448605. |
however, a statistically significant positive correlation between the medicament dose, p53, apoptosis, and bcl-2 was registered (p<0.05). |
2013-08-14 |
2023-08-12 |
Not clear |
| Jing Zhou, Gang Li, Zhi-Hua Wang, Li-Ping Wang, Pu-Jiang Don. Effects of low-dose hydroxychloroquine on expression of phosphorylated Akt and p53 proteins and cardiomyocyte apoptosis in peri-infarct myocardium in rats. Experimental and clinical cardiology. vol 18. issue 2. 2013-08-13. PMID:23940455. |
effects of low-dose hydroxychloroquine on expression of phosphorylated akt and p53 proteins and cardiomyocyte apoptosis in peri-infarct myocardium in rats. |
2013-08-13 |
2023-08-12 |
rat |
| Jing Zhou, Gang Li, Zhi-Hua Wang, Li-Ping Wang, Pu-Jiang Don. Effects of low-dose hydroxychloroquine on expression of phosphorylated Akt and p53 proteins and cardiomyocyte apoptosis in peri-infarct myocardium in rats. Experimental and clinical cardiology. vol 18. issue 2. 2013-08-13. PMID:23940455. |
low-dose hydroxychloroquine (hcq) and ataxia-telangiectasia-mutated (atm) protein kinase have recently been postulated to be beneficial for the prevention of the age-associated metabolic syndrome including hypertension, hypercholesterolemia and glucose intolerance; however, the effects of low-dose hcq on the expression of atm downstream phosphorylated akt (protein kinase b) and p53 proteins and cardiomyocyte apoptosis in the peri-infarct myocardium remain unclear. |
2013-08-13 |
2023-08-12 |
rat |
| James A McCubrey, Zoya N Demidenk. Recent discoveries in the cycling, growing and aging of the p53 field. Aging. vol 4. issue 12. 2013-08-12. PMID:23425920. |
here we review such topics as suppression of epigenetic silencing of a large number of non-coding rnas, role of p53 in suppression of the senescence phenotype, inhibition of oncogenic metabolism, protection of normal cells from chemotherapy and even tumor suppression without apoptosis and cell cycle arrest. |
2013-08-12 |
2023-08-12 |
Not clear |
| Kyoung-Hee Lee, Chul-Gyu Yo. Simultaneous inactivation of GSK-3β suppresses quercetin-induced apoptosis by inhibiting the JNK pathway. American journal of physiology. Lung cellular and molecular physiology. vol 304. issue 11. 2013-08-09. PMID:23564507. |
blockade of jnk activation by overexpression of dominant negative jnk1 suppressed apoptosis by quercetin via inhibition of caspase-3 activation and reduction of p53 and bax expression. |
2013-08-09 |
2023-08-12 |
Not clear |
| Annapina Russo, Davide Esposito, Morena Catillo, Concetta Pietropaolo, Elvira Crescenzi, Giulia Russ. Human rpL3 induces G₁/S arrest or apoptosis by modulating p21 (waf1/cip1) levels in a p53-independent manner. Cell cycle (Georgetown, Tex.). vol 12. issue 1. 2013-08-08. PMID:23255119. |
many evidences show that a subset of ribosomal proteins are involved in the regulation of the cell cycle and apoptosis through modulation of p53 activity. |
2013-08-08 |
2023-08-12 |
human |
| Delu Zhang, Chunxiang Hu, Gaohong Wang, Dunhai Li, Genbao Li, Yongding Li. Zebrafish neurotoxicity from aphantoxins--cyanobacterial paralytic shellfish poisons (PSPs) from Aphanizomenon flos-aquae DC-1. Environmental toxicology. vol 28. issue 5. 2013-08-07. PMID:21710505. |
rt-pcr revealed that mrna levels of the apoptosis-related genes encoding p53, bax, caspase-3, and c-jun were upregulated after aphantoxin exposure, but there was no evidence of dna laddering; apoptosis could take place by pathways independent of dna fragmentation. |
2013-08-07 |
2023-08-12 |
human |
| Qiong Cai, Liang Lv, Qian Shao, Xiao Li, Aiping Dia. Human papillomavirus early proteins and apoptosis. Archives of gynecology and obstetrics. vol 287. issue 3. 2013-08-07. PMID:23263171. |
the oncoproteins e6 can inhibit the apoptosis mainly through p53 pathway. |
2013-08-07 |
2023-08-12 |
human |
| Ryosuke Fukuda, Mary Ann Suico, Kosuke Koyama, Kohei Omachi, Yukari Kai, Shingo Matsuyama, Kazunori Mitsutake, Manabu Taura, Saori Morino-Koga, Tsuyoshi Shuto, Hirofumi Ka. Mild electrical stimulation at 0.1-ms pulse width induces p53 protein phosphorylation and G2 arrest in human epithelial cells. The Journal of biological chemistry. vol 288. issue 22. 2013-08-06. PMID:23599430. |
considering that mes is a form of physiological stress, we hypothesized that it can activate the tumor suppressor p53, which is a key modulator of the cell cycle and apoptosis in response to cell stresses. |
2013-08-06 |
2023-08-12 |
human |
| Seong-Jun Cho, Andrea Rossi, Yong-Sam Jung, Wensheng Yan, Gang Liu, Jin Zhang, Min Zhang, Xinbin Che. Ninjurin1, a target of p53, regulates p53 expression and p53-dependent cell survival, senescence, and radiation-induced mortality. Proceedings of the National Academy of Sciences of the United States of America. vol 110. issue 23. 2013-08-06. PMID:23690620. |
the tumor suppressor protein p53 plays a crucial role in coordinating cellular processes, such as cell cycle arrest, apoptosis, and senescence. |
2013-08-06 |
2023-08-12 |
mouse |
| Seong-Jun Cho, Andrea Rossi, Yong-Sam Jung, Wensheng Yan, Gang Liu, Jin Zhang, Min Zhang, Xinbin Che. Ninjurin1, a target of p53, regulates p53 expression and p53-dependent cell survival, senescence, and radiation-induced mortality. Proceedings of the National Academy of Sciences of the United States of America. vol 110. issue 23. 2013-08-06. PMID:23690620. |
taken together, we provided evidence that ninj1 is a p53 target and modulates p53 mrna translation and p53-dependent premature senescence, cell proliferation, apoptosis, and radiation-induced mortality in vitro and in vivo. |
2013-08-06 |
2023-08-12 |
mouse |