| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yusra Al Dhaheri, Ali Eid, Synan AbuQamar, Samir Attoub, Mohammad Khasawneh, Ghenima Aiche, Soleiman Hisaindee, Rabah Iratn. Mitotic arrest and apoptosis in breast cancer cells induced by Origanum majorana extract: upregulation of TNF-α and downregulation of survivin and mutant p53. PloS one. vol 8. issue 2. 2013-09-03. PMID:23451065. |
mitotic arrest and apoptosis in breast cancer cells induced by origanum majorana extract: upregulation of tnf-α and downregulation of survivin and mutant p53. |
2013-09-03 |
2023-08-12 |
Not clear |
| Bi-cheng Yang, Xiu-jie Pan, Zhi-hua Yang, Feng-jun Xiao, Xing-yu Liu, Mao-xiang Zhu, Jian-ping Xi. Crotonaldehyde induces apoptosis in alveolar macrophages through intracellular calcium, mitochondria and p53 signaling pathways. The Journal of toxicological sciences. vol 38. issue 2. 2013-09-03. PMID:23535401. |
crotonaldehyde induces apoptosis in alveolar macrophages through intracellular calcium, mitochondria and p53 signaling pathways. |
2013-09-03 |
2023-08-12 |
Not clear |
| Bi-cheng Yang, Xiu-jie Pan, Zhi-hua Yang, Feng-jun Xiao, Xing-yu Liu, Mao-xiang Zhu, Jian-ping Xi. Crotonaldehyde induces apoptosis in alveolar macrophages through intracellular calcium, mitochondria and p53 signaling pathways. The Journal of toxicological sciences. vol 38. issue 2. 2013-09-03. PMID:23535401. |
crotonaldehyde-induced apoptosis was characterized by ros generation, gsh depletion, loss of mitochondrial membrane potential (ΔΨm), the release of cytochrome c from mitochondria, caspase-3/7 and caspase-9 activation, elevation of intracellular ca(2+) concentration and the increase of p53 expression. |
2013-09-03 |
2023-08-12 |
Not clear |
| Bi-cheng Yang, Xiu-jie Pan, Zhi-hua Yang, Feng-jun Xiao, Xing-yu Liu, Mao-xiang Zhu, Jian-ping Xi. Crotonaldehyde induces apoptosis in alveolar macrophages through intracellular calcium, mitochondria and p53 signaling pathways. The Journal of toxicological sciences. vol 38. issue 2. 2013-09-03. PMID:23535401. |
furthermore, pretreatment with either p53 inhibitor pifithrin-α or calcium chelator bapta-am effectively attenuated apoptosis induced by crotonaldehyde. |
2013-09-03 |
2023-08-12 |
Not clear |
| Bi-cheng Yang, Xiu-jie Pan, Zhi-hua Yang, Feng-jun Xiao, Xing-yu Liu, Mao-xiang Zhu, Jian-ping Xi. Crotonaldehyde induces apoptosis in alveolar macrophages through intracellular calcium, mitochondria and p53 signaling pathways. The Journal of toxicological sciences. vol 38. issue 2. 2013-09-03. PMID:23535401. |
taken together, our results showed that crotonaldehyde induce apoptosis in alveolar macrophages through intracellular calcium, mitochondria and p53 signaling pathways. |
2013-09-03 |
2023-08-12 |
Not clear |
| Nansong Liu, Jiadong Wang, Jifeng Wang, Rukai Wang, Zhongle Liu, Yao Yu, Hong L. ING5 is a Tip60 cofactor that acetylates p53 in response to DNA damage. Cancer research. vol 73. issue 12. 2013-08-30. PMID:23576563. |
ing5 was required for acetylation of p53 at k120, and p53 acetylated at k120 subsequently bound to the promoters of its target apoptotic genes, bax and gadd45, to promote their expression and lead to apoptosis. |
2013-08-30 |
2023-08-12 |
Not clear |
| Samir S El-Dahr, Zubaida Saifudee. Interactions between BdkrB2 and p53 genes in the developing kidney. Biological chemistry. vol 394. issue 3. 2013-08-29. PMID:23152407. |
the underlying mechanism is p53 stabilization and mediated apoptosis and repression of the terminal epithelial differentiation program. |
2013-08-29 |
2023-08-12 |
mouse |
| Gangadhara R Sareddy, Binoj C Nair, Samaya K Krishnan, Vijay K Gonugunta, Quan-guang Zhang, Takayoshi Suzuki, Naoki Miyata, Andrew J Brenner, Darrell W Brann, Ratna K Vadlamud. KDM1 is a novel therapeutic target for the treatment of gliomas. Oncotarget. vol 4. issue 1. 2013-08-29. PMID:23248157. |
inhibition of kdm1 increased levels of h3k4-me2 and h3k9-ac histone modifications, reduced h3k9-me2 modification and promoted expression of p53 target genes (p21 and puma), leading to apoptosis of glioma xenograft tumors. |
2013-08-29 |
2023-08-12 |
mouse |
| Mélodie B Plourde, Aïda Morchid, Lolita Iranezereza, Lionel Berthou. The Bcl-2/Bcl-xL inhibitor BH3I-2' affects the dynamics and subcellular localization of sumoylated proteins. The international journal of biochemistry & cell biology. vol 45. issue 4. 2013-08-29. PMID:23375957. |
sumoylation modulates many proteins implicated in apoptosis such as fas, tnfr1, daxx, p53 and its regulator mdm2. |
2013-08-29 |
2023-08-12 |
Not clear |
| Norma Serrano-García, José Pedraza-Chaverri, José Juan Mares-Sámano, Marisol Orozco-Ibarra, Arturo Cruz-Salgado, Anabel Jiménez-Anguiano, Julio Sotelo, Cristina Trejo-Solí. Antiapoptotic Effects of EGb 761. Evidence-based complementary and alternative medicine : eCAM. vol 2013. 2013-08-28. PMID:23983787. |
other effects include the reduction of oxidative stress (which has been related to the occurrence of vascular, degenerative, and proliferative diseases), coupled to strong induction of phase ii-detoxifying and cellular defense enzymes by nrf2/are activation, in addition to the modulation of transcription factors, such as creb, hif-1 α , nf- κ b, ap-1, and p53, involved in the apoptosis process. |
2013-08-28 |
2023-08-12 |
Not clear |
| Kun-Han Chuang, Chih-Shen Lu, Yu Ru Kou, Yuh-Lin W. Cell cycle regulation by glucosamine in human pulmonary epithelial cells. Pulmonary pharmacology & therapeutics. vol 26. issue 2. 2013-08-27. PMID:23128353. |
altogether, our results suggest that a high dose of glucosamine may inhibit cell proliferation through apoptosis and disturb cell cycle progression with a halt at g(0)/g(1) phase, and that this occurs, at least in part, by a reduction in rb phosphorylation together with modulation of p21, p53 and ho-1 expression, and nuclear p21 accumulation. |
2013-08-27 |
2023-08-12 |
human |
| Feng Gao, Min Yao, Yonghong Shi, Jun Hao, Yunzhuo Ren, Qingjuan Liu, Xiaomeng Wang, Huijun Dua. Notch pathway is involved in high glucose-induced apoptosis in podocytes via Bcl-2 and p53 pathways. Journal of cellular biochemistry. vol 114. issue 5. 2013-08-27. PMID:23129176. |
notch pathway is involved in high glucose-induced apoptosis in podocytes via bcl-2 and p53 pathways. |
2013-08-27 |
2023-08-12 |
Not clear |
| Feng Gao, Min Yao, Yonghong Shi, Jun Hao, Yunzhuo Ren, Qingjuan Liu, Xiaomeng Wang, Huijun Dua. Notch pathway is involved in high glucose-induced apoptosis in podocytes via Bcl-2 and p53 pathways. Journal of cellular biochemistry. vol 114. issue 5. 2013-08-27. PMID:23129176. |
here we demonstrated that high glucose (hg) upregulated notch pathway in podocytes accompanied with the alteration of bcl-2 and p53 pathways, subsequently leading to podocytes apoptosis. |
2013-08-27 |
2023-08-12 |
Not clear |
| Feng Gao, Min Yao, Yonghong Shi, Jun Hao, Yunzhuo Ren, Qingjuan Liu, Xiaomeng Wang, Huijun Dua. Notch pathway is involved in high glucose-induced apoptosis in podocytes via Bcl-2 and p53 pathways. Journal of cellular biochemistry. vol 114. issue 5. 2013-08-27. PMID:23129176. |
these findings suggest that notch pathway mediates hg-induced podocytes apoptosis via bcl-2 and p53 pathways. |
2013-08-27 |
2023-08-12 |
Not clear |
| Nozomu Kamiura, Junichi Hirahashi, Yumi Matsuzaki, Mana Idei, Osamu Takase, Toshiro Fujita, Tsuyoshi Takato, Keiichi Hishikaw. Basic helix-loop-helix transcriptional factor MyoR regulates BMP-7 in acute kidney injury. American journal of physiology. Renal physiology. vol 304. issue 9. 2013-08-27. PMID:23515721. |
to clarify the mechanism of severe cisplatin-induced damage and apoptosis in myor(-/-) mice, we focused on the p53 signaling pathway and bone morphogenic protein-7 (bmp-7). |
2013-08-27 |
2023-08-12 |
mouse |
| Fernando J López-Díaz, Philippe Gascard, Sri Kripa Balakrishnan, Jianxin Zhao, Sonia V Del Rincon, Charles Spruck, Thea D Tlsty, Beverly M Emerso. Coordinate transcriptional and translational repression of p53 by TGF-β1 impairs the stress response. Molecular cell. vol 50. issue 4. 2013-08-27. PMID:23706820. |
we demonstrate that tgf-β1 signaling interferes with the stress response through coordinate transcriptional and translational repression of p53 levels, which reduces p53-activated transcription, and apoptosis in precancerous cells. |
2013-08-27 |
2023-08-12 |
Not clear |
| Gurpreet Kaur Dhami, Huadong Liu, Marek Galka, Courtney Voss, Ran Wei, Kimberly Muranko, Tomonori Kaneko, Sean P Cregan, Lin Li, Shawn Shun-Cheng L. Dynamic methylation of Numb by Set8 regulates its binding to p53 and apoptosis. Molecular cell. vol 50. issue 4. 2013-08-27. PMID:23706821. |
dynamic methylation of numb by set8 regulates its binding to p53 and apoptosis. |
2013-08-27 |
2023-08-12 |
Not clear |
| Mehdi Nikbakht Dastjerdi, Mohammad R Salahshoor, Mohammad Mardani, Batool Hashemibeni, Shiva Roshankha. The effect of CTB on P53 protein acetylation and consequence apoptosis on MCF-7 and MRC-5 cell lines. Advanced biomedical research. vol 2. 2013-08-26. PMID:23977652. |
the effect of ctb on p53 protein acetylation and consequence apoptosis on mcf-7 and mrc-5 cell lines. |
2013-08-26 |
2023-08-12 |
Not clear |
| Mehdi Nikbakht Dastjerdi, Mohammad R Salahshoor, Mohammad Mardani, Batool Hashemibeni, Shiva Roshankha. The effect of CTB on P53 protein acetylation and consequence apoptosis on MCF-7 and MRC-5 cell lines. Advanced biomedical research. vol 2. 2013-08-26. PMID:23977652. |
p300 is a member of the mammalian histone acetyl transferase (hat) family, an enzyme that acetylates histones and several non-histone proteins including p53 (the most important tumor suppressor gene) during stress, which plays an important role in the apoptosis of tumor cells. |
2013-08-26 |
2023-08-12 |
Not clear |
| Peng Xiao, Yingjie Hao, Xu Zhu, Xuejian W. p53 contributes to quercetin-induced apoptosis in human rheumatoid arthritis fibroblast-like synoviocytes. Inflammation. vol 36. issue 2. 2013-08-23. PMID:22983795. |
p53 contributes to quercetin-induced apoptosis in human rheumatoid arthritis fibroblast-like synoviocytes. |
2013-08-23 |
2023-08-12 |
human |