| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Si Hyoung Kim, Jun Goo Kang, Chul Sik Kim, Sung-Hee Ihm, Moon Gi Choi, Hyung Joon Yoo, Seong Jin Le. Apigenin induces c-Myc-mediated apoptosis in FRO anaplastic thyroid carcinoma cells. Molecular and cellular endocrinology. vol 369. issue 1-2. 2013-09-16. PMID:23376608. |
in conclusion, our results indicate that apigenin induces apoptosis mediated via c-myc with concomitant phosphorylation of p53 and p38 in fro atc cells. |
2013-09-16 |
2023-08-12 |
Not clear |
| Tsan-Hung Chiu, Kai-Ying Lan, Mei-Due Yang, Jen-Jyh Lin, Te-Chun Hsia, Chin-Tung Wu, Jai-Sing Yang, Fu-Shin Chueh, Jing-Gung Chun. Diallyl sulfide promotes cell-cycle arrest through the p53 expression and triggers induction of apoptosis via caspase- and mitochondria-dependent signaling pathways in human cervical cancer Ca Ski cells. Nutrition and cancer. vol 65. issue 3. 2013-09-16. PMID:23530650. |
diallyl sulfide promotes cell-cycle arrest through the p53 expression and triggers induction of apoptosis via caspase- and mitochondria-dependent signaling pathways in human cervical cancer ca ski cells. |
2013-09-16 |
2023-08-12 |
human |
| Gui-Bo Sun, Meng Qin, Jing-xue Ye, Rui-le Pan, Xiang-bao Meng, Min Wang, Yun Luo, Zong-yang Li, Hong-wei Wang, Xiao-bo Su. Inhibitory effects of myricitrin on oxidative stress-induced endothelial damage and early atherosclerosis in ApoE-/- mice. Toxicology and applied pharmacology. vol 271. issue 1. 2013-09-16. PMID:23639522. |
myricitrin treatment also significantly decreased h2o2-induced apoptosis in vecs, which was associated with significant inhibition of p53 gene expression, activation of caspase-3 and the mapk signaling pathway, and alteration of the patterns of pro-apoptotic and anti-apoptotic gene expression. |
2013-09-16 |
2023-08-12 |
mouse |
| Saurabh Wadhwa, Russell J Mumpe. D-penicillamine and other low molecular weight thiols: review of anticancer effects and related mechanisms. Cancer letters. vol 337. issue 1. 2013-09-16. PMID:23727371. |
some of the mechanisms that have been proposed include a p53 mediated apoptosis, thiyl radical induced dna damage, membrane damage through lipid peroxidation, anti-angiogenic effects induced by inhibition of matrix metalloproteinase enzymes and angiostatin generation. |
2013-09-16 |
2023-08-12 |
Not clear |
| Leslie Calapre, Elin S Gray, Mel Zima. Heat stress: a risk factor for skin carcinogenesis. Cancer letters. vol 337. issue 1. 2013-09-16. PMID:23748013. |
here we review studies demonstrating that heat stress-activated heat shock proteins such as hsp72 and hsp90 can influence signalling pathways such as mapk, jnk and p53, which are all involved in regulating cell proliferation, survival and apoptosis. |
2013-09-16 |
2023-08-12 |
Not clear |
| Bilegtsaikhan Tsolmongyn, Naoki Koide, Erdenezaya Odkhuu, Abedul Haque, Yoshikazu Naiki, Takayuki Komatsu, Tomoaki Yoshida, Takashi Yokoch. Lipopolysaccharide prevents valproic acid-induced apoptosis via activation of nuclear factor-κB and inhibition of p53 activation. Cellular immunology. vol 282. issue 2. 2013-09-16. PMID:23770718. |
lipopolysaccharide prevents valproic acid-induced apoptosis via activation of nuclear factor-κb and inhibition of p53 activation. |
2013-09-16 |
2023-08-12 |
mouse |
| Bilegtsaikhan Tsolmongyn, Naoki Koide, Erdenezaya Odkhuu, Abedul Haque, Yoshikazu Naiki, Takayuki Komatsu, Tomoaki Yoshida, Takashi Yokoch. Lipopolysaccharide prevents valproic acid-induced apoptosis via activation of nuclear factor-κB and inhibition of p53 activation. Cellular immunology. vol 282. issue 2. 2013-09-16. PMID:23770718. |
lps inhibited vpa-induced p53 activation and pifithrin-α as a p53 inhibitor as well as lps prevented vpa-induced apoptosis. |
2013-09-16 |
2023-08-12 |
mouse |
| Bilegtsaikhan Tsolmongyn, Naoki Koide, Erdenezaya Odkhuu, Abedul Haque, Yoshikazu Naiki, Takayuki Komatsu, Tomoaki Yoshida, Takashi Yokoch. Lipopolysaccharide prevents valproic acid-induced apoptosis via activation of nuclear factor-κB and inhibition of p53 activation. Cellular immunology. vol 282. issue 2. 2013-09-16. PMID:23770718. |
taken together, lps was suggested to prevent vpa-induced apoptosis via activation of anti-apoptotic nf-κb and inhibition of pro-apoptotic p53 activation. |
2013-09-16 |
2023-08-12 |
mouse |
| Soham Mitra, Tarun Keswani, Nabanita Ghosh, Suranjana Goswami, Anuradha Datta, Salomie Das, Subhajit Maity, Arindam Bhattacharyy. Copper induced immunotoxicity promote differential apoptotic pathways in spleen and thymus. Toxicology. vol 306. 2013-09-13. PMID:23313662. |
in case of spleen, ros generation and mitochondrial trans-membrane potential changes promotes intrinsic pathway of apoptosis that was p53 independent, ultimately leads to decrease in cd4(+) t cell population and increase in cd8(+) t cell population. |
2013-09-13 |
2023-08-12 |
mouse |
| Soham Mitra, Tarun Keswani, Nabanita Ghosh, Suranjana Goswami, Anuradha Datta, Salomie Das, Subhajit Maity, Arindam Bhattacharyy. Copper induced immunotoxicity promote differential apoptotic pathways in spleen and thymus. Toxicology. vol 306. 2013-09-13. PMID:23313662. |
however in case of thymus, ros generation and mitochondrial trans-membrane potential changes lead to death receptor that regulate extrinsic and intrinsic pathways of apoptosis and the apoptotic mechanism which was p53 dependent. |
2013-09-13 |
2023-08-12 |
mouse |
| Shenggui Liu, Wenqiang Cao, Lianling Yu, Wenjie Zheng, Linlin Li, Cundong Fan, Tianfeng Che. Zinc(II) complexes containing bis-benzimidazole derivatives as a new class of apoptosis inducers that trigger DNA damage-mediated p53 phosphorylation in cancer cells. Dalton transactions (Cambridge, England : 2003). vol 42. issue 16. 2013-09-13. PMID:23463103. |
zinc(ii) complexes containing bis-benzimidazole derivatives as a new class of apoptosis inducers that trigger dna damage-mediated p53 phosphorylation in cancer cells. |
2013-09-13 |
2023-08-12 |
human |
| Chao Dai, Dingding Shi, Wei G. Negative regulation of the acetyltransferase TIP60-p53 interplay by UHRF1 (ubiquitin-like with PHD and RING finger domains 1). The Journal of biological chemistry. vol 288. issue 27. 2013-09-13. PMID:23677994. |
in contrast, rnai-mediated knockdown of uhrf1 increases the endogenous levels of p53 acetylation at k120 and p53-mediated apoptosis is significantly enhanced in uhrf1-depleted cells. |
2013-09-13 |
2023-08-12 |
Not clear |
| Yuwarat Porameesanaporn, Wanlaya Uthaisang-Tanechpongtamb, Faongchat Jarintanan, Suchada Jongrungruangchok, Benjamas Thanomsub Wongsatayano. Terrein induces apoptosis in HeLa human cervical carcinoma cells through p53 and ERK regulation. Oncology reports. vol 29. issue 4. 2013-09-12. PMID:23417151. |
terrein induces apoptosis in hela human cervical carcinoma cells through p53 and erk regulation. |
2013-09-12 |
2023-08-12 |
human |
| Yuwarat Porameesanaporn, Wanlaya Uthaisang-Tanechpongtamb, Faongchat Jarintanan, Suchada Jongrungruangchok, Benjamas Thanomsub Wongsatayano. Terrein induces apoptosis in HeLa human cervical carcinoma cells through p53 and ERK regulation. Oncology reports. vol 29. issue 4. 2013-09-12. PMID:23417151. |
this study is the first to show that terrein has an effect on the anticancer properties in cervical cancer cells by inducing apoptosis through p53 and erk regulation. |
2013-09-12 |
2023-08-12 |
human |
| Chung-Hsien Liu, Chingju Lin, Kan-Jen Tsai, Yi-Ching Chuang, Ya-Ling Huang, Tsung-Hsien Lee, Li-Jiau Huang, Hsu-Chin Cha. Biological evaluation of 9-[(6-chloropyridin-4-yl)methyl]-9H-carbazole-3-carbinol as an anticancer agent. Oncology reports. vol 29. issue 4. 2013-09-12. PMID:23443304. |
also, hyl-6d treatment induced mcf-7 cell apoptosis and this was accompanied by a decreased expression of bcl-2, increased levels of p53 and bcl-xs and the activation of caspase-9. |
2013-09-12 |
2023-08-12 |
human |
| Michael Thornton, Mohammed A Aslam, Elizabeth M Tweedle, Chin Ang, Fiona Campbell, Richard Jackson, Eithne Costello, Paul S Rooney, Nikolina Vlatković, Mark T Boy. The unfolded protein response regulator GRP78 is a novel predictive biomarker in colorectal cancer. International journal of cancer. vol 133. issue 6. 2013-09-12. PMID:23456958. |
in vitro, inhibition of grp78 reduces apoptosis in response to 5-fu in p53 wild-type cells. |
2013-09-12 |
2023-08-12 |
Not clear |
| Raquel Espín, Francisco J Roca, Sergio Candel, María P Sepulcre, Juan M González-Rosa, Francisca Alcaraz-Pérez, José Meseguer, María L Cayuela, Nadia Mercader, Victoriano Muler. TNF receptors regulate vascular homeostasis in zebrafish through a caspase-8, caspase-2 and P53 apoptotic program that bypasses caspase-3. Disease models & mechanisms. vol 6. issue 2. 2013-09-11. PMID:22956347. |
similarly, tnfα promotes the apoptosis of human endothelial cells through tnfrsf1a and triggers caspase-2 and p53 activation. |
2013-09-11 |
2023-08-12 |
human |
| Haiwei Mou, Zongmeng Li, Pengle Yao, Shu Zhuo, Wei Luan, Bo Deng, Lihua Qian, Mengmei Yang, Hong Mei, Yingying L. Knockdown of FAM3B triggers cell apoptosis through p53-dependent pathway. The international journal of biochemistry & cell biology. vol 45. issue 3. 2013-09-11. PMID:23246487. |
silencing p53 could almost completely reverse fam3b knockdown induced upregulation of bax, downregulation of bcl-2, cleavage of caspases-8, -9, -3, and apoptotic cell death, suggesting p53-dependent pathway plays critical roles in fam3b silencing induced apoptosis. |
2013-09-11 |
2023-08-12 |
mouse |
| M Kracikova, G Akiri, A George, R Sachidanandam, S A Aaronso. A threshold mechanism mediates p53 cell fate decision between growth arrest and apoptosis. Cell death and differentiation. vol 20. issue 4. 2013-09-11. PMID:23306555. |
a threshold mechanism mediates p53 cell fate decision between growth arrest and apoptosis. |
2013-09-11 |
2023-08-12 |
Not clear |
| M Kracikova, G Akiri, A George, R Sachidanandam, S A Aaronso. A threshold mechanism mediates p53 cell fate decision between growth arrest and apoptosis. Cell death and differentiation. vol 20. issue 4. 2013-09-11. PMID:23306555. |
the p53 tumor suppressor responds to certain cellular stresses by inducing transcriptional programs that can lead to growth arrest or apoptosis. |
2013-09-11 |
2023-08-12 |
Not clear |