| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Peng Xiao, Yingjie Hao, Xu Zhu, Xuejian W. p53 contributes to quercetin-induced apoptosis in human rheumatoid arthritis fibroblast-like synoviocytes. Inflammation. vol 36. issue 2. 2013-08-23. PMID:22983795. |
small interfering rnas were used to knock down the expression of protein 53 (p53) and analyze the role of p53 in quercetin-induced apoptosis in raflss. |
2013-08-23 |
2023-08-12 |
human |
| Peng Xiao, Yingjie Hao, Xu Zhu, Xuejian W. p53 contributes to quercetin-induced apoptosis in human rheumatoid arthritis fibroblast-like synoviocytes. Inflammation. vol 36. issue 2. 2013-08-23. PMID:22983795. |
pretreatment with pifithrin-α, a p53 inhibitor, significantly diminished p53 phosphorylation at the concentration of 30 μm and abrogated quercetin-induced apoptosis in a dose-dependent manner. |
2013-08-23 |
2023-08-12 |
human |
| Peng Xiao, Yingjie Hao, Xu Zhu, Xuejian W. p53 contributes to quercetin-induced apoptosis in human rheumatoid arthritis fibroblast-like synoviocytes. Inflammation. vol 36. issue 2. 2013-08-23. PMID:22983795. |
quercetin-induced apoptosis was also significantly blocked by p53 silencing, further suggesting the involvement of p53 in quercetin-induced apoptosis in raflss. |
2013-08-23 |
2023-08-12 |
human |
| Peng Xiao, Yingjie Hao, Xu Zhu, Xuejian W. p53 contributes to quercetin-induced apoptosis in human rheumatoid arthritis fibroblast-like synoviocytes. Inflammation. vol 36. issue 2. 2013-08-23. PMID:22983795. |
our study indicated that quercetin-induced apoptosis of raflss is through mitochondrial pathway, in which p53 plays an important role. |
2013-08-23 |
2023-08-12 |
human |
| Y K Adlakha, N Sain. miR-128 exerts pro-apoptotic effect in a p53 transcription-dependent and -independent manner via PUMA-Bak axis. Cell death & disease. vol 4. 2013-08-23. PMID:23492773. |
furthermore, mir-128 induces apoptosis in wild (wt) p53 as well as in mutant p53-expressing cells in a p53-dependent and -independent manner via induction of puma. |
2013-08-23 |
2023-08-12 |
human |
| Y K Adlakha, N Sain. miR-128 exerts pro-apoptotic effect in a p53 transcription-dependent and -independent manner via PUMA-Bak axis. Cell death & disease. vol 4. 2013-08-23. PMID:23492773. |
this study emphasizes that mir-128 is a novel mitochondria-targeted mirna that can be further evaluated as a chemotherapeutic agent for human cancers as it induces apoptosis irrespective of p53 status. |
2013-08-23 |
2023-08-12 |
human |
| E M Messier, K Bahmed, R M Tuder, H W Chu, R P Bowler, B Kosmide. Trolox contributes to Nrf2-mediated protection of human and murine primary alveolar type II cells from injury by cigarette smoke. Cell death & disease. vol 4. 2013-08-23. PMID:23559007. |
we analyzed oxidative stress by 4-hydroxynonenal expression, reactive oxygen species (ros) generation by amplex red hydrogen peroxide assay, nrf2, heme oxygenase 1, p53 and p53-binding protein 1 (53bp1) expression by immonoblotting, nrf2 nuclear translocation, nrf2 and p53 dna-binding activities, apoptosis by terminal deoxynucleotidyl transferase-mediated dutp nick-end labeling assay and cytokine production by elisa. |
2013-08-23 |
2023-08-12 |
mouse |
| Salina Y Saddic. In vivo and in vitro studies on apoptosis in OSE cells and inclusion cysts of pregnant heifers. Saudi journal of biological sciences. vol 20. issue 3. 2013-08-20. PMID:23961245. |
this study was undertaken to decipher whether or not there is any relationship between progesterone (also oestrogen)-mediated ovarian surface epithelium (ose) apoptosis and expression of p53, a cell-cycle arresting protein and potential tumour suppressor. |
2013-08-20 |
2023-08-12 |
Not clear |
| Salina Y Saddic. In vivo and in vitro studies on apoptosis in OSE cells and inclusion cysts of pregnant heifers. Saudi journal of biological sciences. vol 20. issue 3. 2013-08-20. PMID:23961245. |
the steroid dosage dependence for apoptosis and p53 expression was also somewhat similar. |
2013-08-20 |
2023-08-12 |
Not clear |
| Salina Y Saddic. In vivo and in vitro studies on apoptosis in OSE cells and inclusion cysts of pregnant heifers. Saudi journal of biological sciences. vol 20. issue 3. 2013-08-20. PMID:23961245. |
assuming that progesterone action is mediated through p53-caused apoptosis as a mechanism to evade malignant transformation of ose cells, p53 expression at mrna and protein level was investigated in the ose layer in proximity to stroma, antrum and corpus luteum (cl). |
2013-08-20 |
2023-08-12 |
Not clear |
| Salina Y Saddic. In vivo and in vitro studies on apoptosis in OSE cells and inclusion cysts of pregnant heifers. Saudi journal of biological sciences. vol 20. issue 3. 2013-08-20. PMID:23961245. |
we conclude that progesterone during cycling and pregnancy may reduce the risk of developing ovarian cancer by ceasing cell cycle and diverting damaged and mutagenized ose cells for apoptosis, and the process may be mediated through elevated p53 synthesis. |
2013-08-20 |
2023-08-12 |
Not clear |
| Hongbo Wang, Pengfei Yu, Jing Bai, Jianqiao Zhang, Liang Kong, Fangxi Zhang, Guangying Du, Shiqian Pei, Lixia Zhang, Yongtao Jiang, Jingwei Tian, Fenghua F. Ocotillol Enhanced the Antitumor Activity of Doxorubicin via p53-Dependent Apoptosis. Evidence-based complementary and alternative medicine : eCAM. vol 2013. 2013-08-19. PMID:23956772. |
compared with dox alone, dox with ocotillol (dox-o) could induce much more cell apoptosis and activate p53 to a much greater degree, which in turn markedly increased expression of proapoptosis genes. |
2013-08-19 |
2023-08-12 |
mouse |
| M-L Dichtel-Danjoy, D Ma, P Dourlen, G Chatelain, F Napoletano, M Robin, M Corbet, C Levet, H Hafsi, P Hainaut, H D Ryoo, J-C Bourdon, B Mollerea. Drosophila p53 isoforms differentially regulate apoptosis and apoptosis-induced proliferation. Cell death and differentiation. vol 20. issue 1. 2013-08-15. PMID:22898807. |
drosophila p53 isoforms differentially regulate apoptosis and apoptosis-induced proliferation. |
2013-08-15 |
2023-08-12 |
drosophila_melanogaster |
| M-L Dichtel-Danjoy, D Ma, P Dourlen, G Chatelain, F Napoletano, M Robin, M Corbet, C Levet, H Hafsi, P Hainaut, H D Ryoo, J-C Bourdon, B Mollerea. Drosophila p53 isoforms differentially regulate apoptosis and apoptosis-induced proliferation. Cell death and differentiation. vol 20. issue 1. 2013-08-15. PMID:22898807. |
understanding the roles of drosophila p53 isoforms in apoptosis and in apoptosis-induced proliferation may shed new light on the roles of p53 isoforms in humans, with important implications in cancer biology. |
2013-08-15 |
2023-08-12 |
drosophila_melanogaster |
| Guanghui Cheng, Dejuan Kong, Xue Hou, Bing Liang, Mengzi He, Nan Liang, Shumei Ma, Xiaodong Li. The tumor suppressor, p53, contributes to radiosensitivity of lung cancer cells by regulating autophagy and apoptosis. Cancer biotherapy & radiopharmaceuticals. vol 28. issue 2. 2013-08-15. PMID:23268708. |
the tumor suppressor, p53, contributes to radiosensitivity of lung cancer cells by regulating autophagy and apoptosis. |
2013-08-15 |
2023-08-12 |
Not clear |
| Guanghui Cheng, Dejuan Kong, Xue Hou, Bing Liang, Mengzi He, Nan Liang, Shumei Ma, Xiaodong Li. The tumor suppressor, p53, contributes to radiosensitivity of lung cancer cells by regulating autophagy and apoptosis. Cancer biotherapy & radiopharmaceuticals. vol 28. issue 2. 2013-08-15. PMID:23268708. |
the tumor suppressor p53 participates not only in regulation of apoptosis, but also in autophagy mechanism. |
2013-08-15 |
2023-08-12 |
Not clear |
| Jie Mei, Ming-Qing Li, Ding Ding, Da-Jin Li, Li-Ping Jin, Wei-Guo Hu, Xiao-Yong Zh. Indoleamine 2,3-dioxygenase-1 (IDO1) enhances survival and invasiveness of endometrial stromal cells via the activation of JNK signaling pathway. International journal of clinical and experimental pathology. vol 6. issue 3. 2013-08-15. PMID:23411497. |
as a result, ido1-overexpression in escs was markedly linked to reduction of apoptosis and p53 expression, and upregulation of survival, proliferation, invasion, as well as expression of mmp-9, cox-2 expression, rather than expression of survivin, mmp-2 and timp-1. |
2013-08-15 |
2023-08-12 |
Not clear |
| Nada Al-Ajmi, May Al-Maghrebi, Waleed Mohammed Renn. (-)-Epigallocatechin-3-gallate Modulates the Differential Expression of Survivin Splice Variants and Protects Spermatogenesis During Testicular Torsion. The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology. vol 17. issue 4. 2013-08-15. PMID:23946684. |
the expression of the survivin variants (140 and 40) and other apoptosis genes (p53, bax and bcl-2) was measured with semi-quantitative rt-pcr. |
2013-08-15 |
2023-08-12 |
mouse |
| Nada Al-Ajmi, May Al-Maghrebi, Waleed Mohammed Renn. (-)-Epigallocatechin-3-gallate Modulates the Differential Expression of Survivin Splice Variants and Protects Spermatogenesis During Testicular Torsion. The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology. vol 17. issue 4. 2013-08-15. PMID:23946684. |
in parallel, there was an increase in the mrna level of p53 and the bax to bcl-2 ratio in support of apoptosis induction. |
2013-08-15 |
2023-08-12 |
mouse |
| Yun-Hee Bae, Jong Hyo Ryu, Hyun-Joo Park, Kwang Rok Kim, Hee-Jun Wee, Ok-Hee Lee, Hye-Ock Jang, Moon-Kyoung Bae, Kyu-Won Kim, Soo-Kyung Ba. Mutant p53-Notch1 Signaling Axis Is Involved in Curcumin-Induced Apoptosis of Breast Cancer Cells. The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology. vol 17. issue 4. 2013-08-15. PMID:23946688. |
the present study aimed to determine whether the mutant p53 can be a potent transcriptional activator of the notch1 in mda-mb-231 cells, and explore the role of this mutant p53-notch1 axis in curcumin-induced apoptosis. |
2013-08-15 |
2023-08-12 |
human |