| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hai Wang, Zhigang J. Inhibition of p53 alleviates prostate cell apoptosis in Escherichia coli‑induced bacterial prostatitis. Molecular medicine reports. vol 20. issue 2. 2019-12-13. PMID:31173258. |
following transfection with p53 sirna, the promotion of cell apoptosis induced by escherichia coli infection was decreased, and the p53 and bax protein expression were additionally decreased. |
2019-12-13 |
2023-08-13 |
human |
| Hai Wang, Zhigang J. Inhibition of p53 alleviates prostate cell apoptosis in Escherichia coli‑induced bacterial prostatitis. Molecular medicine reports. vol 20. issue 2. 2019-12-13. PMID:31173258. |
therefore, it was suggested that escherichia coli increases cell apoptosis in bacterial prostatitis by activating the death receptor pathway involving p53. |
2019-12-13 |
2023-08-13 |
human |
| Hai Wang, Zhigang J. Inhibition of p53 alleviates prostate cell apoptosis in Escherichia coli‑induced bacterial prostatitis. Molecular medicine reports. vol 20. issue 2. 2019-12-13. PMID:31173258. |
inhibition of p53 alleviated prostate cell apoptosis induced by escherichia coli. |
2019-12-13 |
2023-08-13 |
human |
| Ru-Wei Lin, Cheng-Jung Ho, Hsin-Wen Chen, Yu-Hsuan Pao, Li-En Chen, Min-Chi Yang, Shih-Bo Huang, Shiaw Wang, Chung-Hwan Chen, Chihuei Wan. P53 enhances apoptosis induced by doxorubicin only under conditions of severe DNA damage. Cell cycle (Georgetown, Tex.). vol 17. issue 17. 2019-12-12. PMID:30198376. |
p53 enhances apoptosis induced by doxorubicin only under conditions of severe dna damage. |
2019-12-12 |
2023-08-13 |
Not clear |
| Ru-Wei Lin, Cheng-Jung Ho, Hsin-Wen Chen, Yu-Hsuan Pao, Li-En Chen, Min-Chi Yang, Shih-Bo Huang, Shiaw Wang, Chung-Hwan Chen, Chihuei Wan. P53 enhances apoptosis induced by doxorubicin only under conditions of severe DNA damage. Cell cycle (Georgetown, Tex.). vol 17. issue 17. 2019-12-12. PMID:30198376. |
however, the comparison of doxorubicin treatment between lncap cells carrying p53-wild type and pc3 cells carrying p53-null suggested that p53 might be essential for maximizing apoptosis. |
2019-12-12 |
2023-08-13 |
Not clear |
| Ru-Wei Lin, Cheng-Jung Ho, Hsin-Wen Chen, Yu-Hsuan Pao, Li-En Chen, Min-Chi Yang, Shih-Bo Huang, Shiaw Wang, Chung-Hwan Chen, Chihuei Wan. P53 enhances apoptosis induced by doxorubicin only under conditions of severe DNA damage. Cell cycle (Georgetown, Tex.). vol 17. issue 17. 2019-12-12. PMID:30198376. |
overexpression of p53 did not affect abt-263-induced apoptosis and nevertheless, the combination of doxorubicin with abt-263 induced higher apoptotic responses than did doxorubicin or abt-263 alone. |
2019-12-12 |
2023-08-13 |
Not clear |
| Ru-Wei Lin, Cheng-Jung Ho, Hsin-Wen Chen, Yu-Hsuan Pao, Li-En Chen, Min-Chi Yang, Shih-Bo Huang, Shiaw Wang, Chung-Hwan Chen, Chihuei Wan. P53 enhances apoptosis induced by doxorubicin only under conditions of severe DNA damage. Cell cycle (Georgetown, Tex.). vol 17. issue 17. 2019-12-12. PMID:30198376. |
these results advocated that doxorubicin-induced dna damage controls p53 function for intensifying apoptosis. |
2019-12-12 |
2023-08-13 |
Not clear |
| Ru-Wei Lin, Cheng-Jung Ho, Hsin-Wen Chen, Yu-Hsuan Pao, Li-En Chen, Min-Chi Yang, Shih-Bo Huang, Shiaw Wang, Chung-Hwan Chen, Chihuei Wan. P53 enhances apoptosis induced by doxorubicin only under conditions of severe DNA damage. Cell cycle (Georgetown, Tex.). vol 17. issue 17. 2019-12-12. PMID:30198376. |
indeed, overexpression of p53 only enhanced apoptosis under conditions of severe dna damage induced by high concentrations of doxorubicin in lncap cells. |
2019-12-12 |
2023-08-13 |
Not clear |
| Ru-Wei Lin, Cheng-Jung Ho, Hsin-Wen Chen, Yu-Hsuan Pao, Li-En Chen, Min-Chi Yang, Shih-Bo Huang, Shiaw Wang, Chung-Hwan Chen, Chihuei Wan. P53 enhances apoptosis induced by doxorubicin only under conditions of severe DNA damage. Cell cycle (Georgetown, Tex.). vol 17. issue 17. 2019-12-12. PMID:30198376. |
thus, we concluded that p53 is a sensor for enhanced apoptosis in response to dna damage stress, not dna replication stress, at least in prostate cancer. |
2019-12-12 |
2023-08-13 |
Not clear |
| C De Paepe, A Aberkane, D Dewandre, W Essahib, K Sermon, M Geens, G Verheyen, H Tournaye, H Van de Veld. BMP4 plays a role in apoptosis during human preimplantation development. Molecular reproduction and development. vol 86. issue 1. 2019-12-12. PMID:30372558. |
we focused on p53, which is known to play a major role in the apoptosis. |
2019-12-12 |
2023-08-13 |
mouse |
| Tamires Cunha Almeida, Camila Chaves Coelho Guerra, Bárbara Letícia Gonçalves De Assis, Rodrigo Dian de Oliveira Aguiar Soares, Camila Carriao Machado Garcia, Angélica Alves Lima, Glenda Nicioli da Silv. Antiproliferative and toxicogenomic effects of resveratrol in bladder cancer cells with different TP53 status. Environmental and molecular mutagenesis. vol 60. issue 8. 2019-12-12. PMID:31095781. |
cell proliferation, clonogenic survival, morphological changes, cell cycle progression, apoptosis rates, genotoxicity, global methylation, immunocytochemistry for p53 and pcna and relative expression profiles of the akt, mtor, rassf1a, hoxb3, src, plk1, and dnmt1 were evaluated. |
2019-12-12 |
2023-08-13 |
Not clear |
| Xin-Tong Wu, Abdur Rahman Ansari, Xin-Xin Pang, Hui-Zhen Li, Zhe-Wei Zhang, You Luo, Muhammad Arshad, Hui Son. Visfatin Plays a Significant Role in Alleviating Lipopolysaccharide-Induced Apoptosis and Autophagy Through PI3K/AKT Signaling Pathway During Acute Lung Injury in Mice. Archivum immunologiae et therapiae experimentalis. vol 67. issue 4. 2019-12-12. PMID:31143985. |
after visfatin treatment, the expression of pro-apoptotic genes bax, bik, and p53 decreased and the expression of anti-apoptotic genes bcl-2 and bcl-xl increased, and expression of autophagy factors lc3 and beclin1 decreased, indicating that visfatin inhibits apoptosis and reduces autophagy. |
2019-12-12 |
2023-08-13 |
mouse |
| Qi Wu, Junmou Hong, Zhiwei Wang, Junxia Hu, Ruoshi Chen, Zhipeng Hu, Bowen Li, Xiaoping Hu, Zhengpei Zhang, Yongle Rua. Abnormal Ribosome Biogenesis Partly Induced p53-Dependent Aortic Medial Smooth Muscle Cell Apoptosis and Oxidative Stress. Oxidative medicine and cellular longevity. vol 2019. 2019-12-11. PMID:31210846. |
in addition, overexpression of bop1 in human aortic smooth muscle cells (hasmcs) inhibited apoptosis and accumulation of p53 under hypoxic conditions, while knockdown of bop1 decreased the protein synthesis rate and motility of hasmcs. |
2019-12-11 |
2023-08-13 |
human |
| Qi Wu, Junmou Hong, Zhiwei Wang, Junxia Hu, Ruoshi Chen, Zhipeng Hu, Bowen Li, Xiaoping Hu, Zhengpei Zhang, Yongle Rua. Abnormal Ribosome Biogenesis Partly Induced p53-Dependent Aortic Medial Smooth Muscle Cell Apoptosis and Oxidative Stress. Oxidative medicine and cellular longevity. vol 2019. 2019-12-11. PMID:31210846. |
the rna polymerase i inhibitor cx-5461 induced apoptosis, ros production, and proliferative inhibition in the hasmcs, which was partly attenuated by p53 knockout. |
2019-12-11 |
2023-08-13 |
human |
| Zachary J Messenger, Jonathan R Hall, Dereje D Jima, John S House, Hann W Tam, Debra A Tokarz, Robert C Smar. C/EBPβ deletion in oncogenic Ras skin tumors is a synthetic lethal event. Cell death & disease. vol 9. issue 11. 2019-12-10. PMID:30323292. |
regressing tumors exhibited elevated levels of apoptosis and p53 protein/activity, while adjacent c/ebpβ-deleted skin did not. |
2019-12-10 |
2023-08-13 |
mouse |
| Zachary J Messenger, Jonathan R Hall, Dereje D Jima, John S House, Hann W Tam, Debra A Tokarz, Robert C Smar. C/EBPβ deletion in oncogenic Ras skin tumors is a synthetic lethal event. Cell death & disease. vol 9. issue 11. 2019-12-10. PMID:30323292. |
co-deletion of c/ebpβ and p53 in oncogenic ras tumors showed p53 is required for tumor regression and elevated apoptosis. |
2019-12-10 |
2023-08-13 |
mouse |
| Zachary J Messenger, Jonathan R Hall, Dereje D Jima, John S House, Hann W Tam, Debra A Tokarz, Robert C Smar. C/EBPβ deletion in oncogenic Ras skin tumors is a synthetic lethal event. Cell death & disease. vol 9. issue 11. 2019-12-10. PMID:30323292. |
rnaseq data analysis of regressing tumors deleted of c/ebpβ indicates a novel interface between p53, type-1 interferon response, and death receptor pathways, which function in concert to produce activation of extrinsic apoptosis pathways. |
2019-12-10 |
2023-08-13 |
mouse |
| Ryo Uehara, Susana M Cerritelli, Naushaba Hasin, Kiran Sakhuja, Mariya London, Jaime Iranzo, Hyongi Chon, Alexander Grinberg, Robert J Crouc. Two RNase H2 Mutants with Differential rNMP Processing Activity Reveal a Threshold of Ribonucleotide Tolerance for Embryonic Development. Cell reports. vol 25. issue 5. 2019-12-10. PMID:30380406. |
estimations of the number of rnmps in dna in these two mutants define a ribonucleotide threshold above which p53 induces apoptosis. |
2019-12-10 |
2023-08-13 |
mouse |
| Svetlana Demyanenko, Valentina Dzreyan, Anatoly Uzdensk. Axotomy-Induced Changes of the Protein Profile in the Crayfish Ventral Cord Ganglia. Journal of molecular neuroscience : MN. vol 68. issue 4. 2019-12-10. PMID:31066008. |
using proteomic antibody microarrays, we showed upregulation of apoptosis execution proteins (bcl-10, caspases 3, 6, and 7, smac/diablo, aif), proapoptotic signaling proteins and transcription factors (c-myc, p38, e2f1, p53, gadd153), and multifunctional proteins capable of initiating apoptosis in specific situations (p75, nmdar2a) in the axotomized vnc ganglia. |
2019-12-10 |
2023-08-13 |
Not clear |
| Shaolong Ma, Chao Zhang, Ziyan Zhang, Yuxuan Dai, Rui Gu, Rui Jian. Geniposide protects PC12 cells from lipopolysaccharide-evoked inflammatory injury via up-regulation of miR-145-5p. Artificial cells, nanomedicine, and biotechnology. vol 47. issue 1. 2019-12-10. PMID:31307231. |
meanwhile, apoptosis driven by lps was mitigated by geniposide, which accompanied with p53, bax and cleaved caspase-3 down-regulation, and bcl-2 up-regulation. |
2019-12-10 |
2023-08-13 |
Not clear |