| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiaoyun Zhang, Yalei Zhao, Peng Kong, Mei Han, Binghui L. Expression of circZNF609 is Down-Regulated in Colorectal Cancer Tissue and Promotes Apoptosis in Colorectal Cancer Cells by Upregulating p53. Medical science monitor : international medical journal of experimental and clinical research. vol 25. 2020-01-24. PMID:31401644. |
expression of circznf609 is down-regulated in colorectal cancer tissue and promotes apoptosis in colorectal cancer cells by upregulating p53. |
2020-01-24 |
2023-08-13 |
human |
| Xiaoyun Zhang, Yalei Zhao, Peng Kong, Mei Han, Binghui L. Expression of circZNF609 is Down-Regulated in Colorectal Cancer Tissue and Promotes Apoptosis in Colorectal Cancer Cells by Upregulating p53. Medical science monitor : international medical journal of experimental and clinical research. vol 25. 2020-01-24. PMID:31401644. |
expression of circznf609 induced apoptosis and upregulated expression of the pro-apoptotic protein, bax, down-regulated the expression of the anti-apoptotic protein, bcl-2, and upregulated p53. |
2020-01-24 |
2023-08-13 |
human |
| Xiaoyun Zhang, Yalei Zhao, Peng Kong, Mei Han, Binghui L. Expression of circZNF609 is Down-Regulated in Colorectal Cancer Tissue and Promotes Apoptosis in Colorectal Cancer Cells by Upregulating p53. Medical science monitor : international medical journal of experimental and clinical research. vol 25. 2020-01-24. PMID:31401644. |
conclusions expression of circznf609 was down-regulated in colorectal cancer tissue and promoted apoptosis in colorectal cancer cells in vitro by upregulating p53. |
2020-01-24 |
2023-08-13 |
human |
| Rebeca Lapresa, Jesús Agulla, Irene Sánchez-Morán, Rubén Zamarreño, Estefanía Prieto, Juan P Bolaños, Angeles Almeid. Amyloid-ß promotes neurotoxicity by Cdk5-induced p53 stabilization. Neuropharmacology. vol 146. 2020-01-23. PMID:30452955. |
the p53 tumor suppressor protein, a key regulator of cell apoptosis, has been described to accumulate in affected brain areas from ad patients. |
2020-01-23 |
2023-08-13 |
Not clear |
| Rebeca Lapresa, Jesús Agulla, Irene Sánchez-Morán, Rubén Zamarreño, Estefanía Prieto, Juan P Bolaños, Angeles Almeid. Amyloid-ß promotes neurotoxicity by Cdk5-induced p53 stabilization. Neuropharmacology. vol 146. 2020-01-23. PMID:30452955. |
to address this issue, here we investigated the involvement of p53 on aß-induced neuronal apoptosis. |
2020-01-23 |
2023-08-13 |
Not clear |
| Hema Negi, Siva Bharath Merugu, Hitesh Bhagavanbhai Mangukiya, Zheqi Li, Bingjie Zhou, Qudsia Sehar, Suchitra Kamle, Fakhar-Un-Nisa Yunus, Dhahiri Saidi Mashausi, Zhenghua Wu, Dawei L. Anterior Gradient-2 monoclonal antibody inhibits lung cancer growth and metastasis by upregulating p53 pathway and without exerting any toxicological effects: A preclinical study. Cancer letters. vol 449. 2020-01-21. PMID:30685412. |
furthermore, mab18a4-treated cancer cell lines showed attenuated proliferation and colony formation, enhanced apoptosis, increased p53 expression, and reduced phosphorylated erk1/2 expression. |
2020-01-21 |
2023-08-13 |
mouse |
| Jinghao Wang, Xiaosong Wu, Jingxin Wang, Luchen Sha. JARID1B modulates breast cancer cell apoptosis by regulating p53 expression. International journal of clinical and experimental pathology. vol 11. issue 9. 2020-01-21. PMID:31949850. |
jarid1b modulates breast cancer cell apoptosis by regulating p53 expression. |
2020-01-21 |
2023-08-13 |
Not clear |
| Jinghao Wang, Xiaosong Wu, Jingxin Wang, Luchen Sha. JARID1B modulates breast cancer cell apoptosis by regulating p53 expression. International journal of clinical and experimental pathology. vol 11. issue 9. 2020-01-21. PMID:31949850. |
the inhibition of p53 by small interfering rna (sirna) reverses the jarid1b sirna-induced increase of apoptosis. |
2020-01-21 |
2023-08-13 |
Not clear |
| Jinghao Wang, Xiaosong Wu, Jingxin Wang, Luchen Sha. JARID1B modulates breast cancer cell apoptosis by regulating p53 expression. International journal of clinical and experimental pathology. vol 11. issue 9. 2020-01-21. PMID:31949850. |
our results collectively suggest that jarid1b plays a key role in breast cancer cell apoptosis, and it may partially achieve this role through p53. |
2020-01-21 |
2023-08-13 |
Not clear |
| Shaoshuai Liang, Danwen Liu, Xixi Li, Maokai Wei, Xiaohan Yu, Qi Li, Huixin Ma, Zhifeng Zhang, Zhenkui Qi. SOX2 participates in spermatogenesis of Zhikong scallop Chlamys farreri. Scientific reports. vol 9. issue 1. 2020-01-20. PMID:30635613. |
go and kegg analysis showed that most degs were related to cell apoptosis (casp2, casp3, casp8), cell proliferation (samd9, crebzf, iqsec1) and spermatogenesis (htt, tusc3, zmynd10, nipbl, mfge8), and enriched in p53, tnf and apoptosis pathways. |
2020-01-20 |
2023-08-13 |
Not clear |
| Zhiqiang Wang, Lili Ding, Jun Zhu, Yinxia Su, Li Wang, Lina Liu, Qi Ma, Hua Ya. Long non-coding RNA MEG3 mediates high glucose-induced endothelial cell dysfunction. International journal of clinical and experimental pathology. vol 11. issue 3. 2020-01-19. PMID:31938204. |
interestingly, meg3 knockdown in huvecs significantly induced proliferation and inhibited apoptosis by upregulating bcl-2 and downregulating bax, caspase-3, and p53. |
2020-01-19 |
2023-08-13 |
Not clear |
| Qian Li, Lei Pang, Hui Shi, Wei Yang, Xin Liu, Guanfang Su, Yu Don. High glucose concentration induces retinal endothelial cell apoptosis by activating p53 signaling pathway. International journal of clinical and experimental pathology. vol 11. issue 5. 2020-01-19. PMID:31938352. |
high glucose concentration induces retinal endothelial cell apoptosis by activating p53 signaling pathway. |
2020-01-19 |
2023-08-13 |
Not clear |
| Qian Li, Lei Pang, Hui Shi, Wei Yang, Xin Liu, Guanfang Su, Yu Don. High glucose concentration induces retinal endothelial cell apoptosis by activating p53 signaling pathway. International journal of clinical and experimental pathology. vol 11. issue 5. 2020-01-19. PMID:31938352. |
in conclusion, high glucose concentration induces apoptosis in retinal endothelial cells by activating p53 signaling pathway. |
2020-01-19 |
2023-08-13 |
Not clear |
| Xiayida Tuerxun, Huerxidan Abudumijiti, Guo Chun Fen, Axiangu Hasim. The functional role of RNF113A in cervical carcinogenesis. International journal of clinical and experimental pathology. vol 12. issue 9. 2020-01-17. PMID:31934207. |
by silencing rnf113a in cscc cell lines, we observed an up-regulation of the p53 protein level, indicating that p53 may function as a target of the rnf113a e3 ligase, and rnf113a may inhibit tumor cell apoptosis by degrading the tp53 protein. |
2020-01-17 |
2023-08-13 |
Not clear |
| Reddymasu Sreenivasulu, Kotthireddy Thirumal Reddy, Pombala Sujitha, C Ganesh Kumar, Rudraraju Ramesh Raj. Synthesis, antiproliferative and apoptosis induction potential activities of novel bis(indolyl)hydrazide-hydrazone derivatives. Bioorganic & medicinal chemistry. vol 27. issue 6. 2020-01-15. PMID:30773423. |
compound 14a induced apoptosis via caspase independent pathway through the participation of mitogen-activated protein kinases (mapk) such as extracellular signal related kinase (erk) and p38 as well as p53 pathways. |
2020-01-15 |
2023-08-13 |
Not clear |
| Xiaofei Zhang, Zihao Qi, Huijing Yin, Gong Yan. Interaction between p53 and Ras signaling controls cisplatin resistance via HDAC4- and HIF-1α-mediated regulation of apoptosis and autophagy. Theranostics. vol 9. issue 4. 2020-01-15. PMID:30867818. |
interaction between p53 and ras signaling controls cisplatin resistance via hdac4- and hif-1α-mediated regulation of apoptosis and autophagy. |
2020-01-15 |
2023-08-13 |
Not clear |
| Alaa El-Din H Sayed, Ahmed M Kotb, Shoji Oda, Shosaku Kashiwada, Hiroshi Mitan. Protective effect of p53 knockout on 4-nonylphenol-induced nephrotoxicity in medaka (Oryzias latipes). Chemosphere. vol 236. 2020-01-15. PMID:31310970. |
therefore, the present study aimed to investigate the protective blocking effect of apoptosis (deficient p53 gene) on 4-nonylphenol (4-np)-induced nephrotoxicity of medaka (oryzias latipes). |
2020-01-15 |
2023-08-13 |
Not clear |
| Fuminori Sakanashi, Michiko Shintani, Masazumi Tsuneyoshi, Hiroyuki Ohsaki, Shingo Kamoshid. Apoptosis, necroptosis and autophagy in colorectal cancer: Associations with tumor aggressiveness and p53 status. Pathology, research and practice. vol 215. issue 7. 2020-01-14. PMID:31097354. |
apoptosis, necroptosis and autophagy in colorectal cancer: associations with tumor aggressiveness and p53 status. |
2020-01-14 |
2023-08-13 |
human |
| Monika Marcinkute, Saeed Afshinjavid, Amos A Fatokun, Farideh A Javi. Fluoxetine selectively induces p53-independent apoptosis in human colorectal cancer cells. European journal of pharmacology. vol 857. 2020-01-14. PMID:31181210. |
in conclusion, fluoxetine's cytotoxicity induces mainly apoptosis and causes dna fragmentation in human colorectal cancer cells, which seemed to be independent of the p53 protein, as no significant difference in death profiles in response to fluoxetine treatment was observed in both the p53-intact and the p53-deleted cell lines. |
2020-01-14 |
2023-08-13 |
human |
| Misato Moriguchi, Tadashi Watanabe, Masahiro Fujimur. Capsaicin Induces ATF4 Translation with Upregulation of CHOP, GADD34 and PUMA. Biological & pharmaceutical bulletin. vol 42. issue 8. 2020-01-14. PMID:31366879. |
chop is associated with apoptosis induction and upregulates growth arrest and dna damage-inducible protein 34 (gadd34) and p53 up-regulated modulator of apoptosis (puma) mrna expression. |
2020-01-14 |
2023-08-13 |
Not clear |