| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mingyu He, Lillian Ro, Jing Liu, Chih-Chang Ch. Folate-decorated arginine-based poly(ester urea urethane) nanoparticles as carriers for gambogic acid and effect on cancer cells. Journal of biomedical materials research. Part A. vol 105. issue 2. 2017-11-02. PMID:27706899. |
the ga at 2 µg/ml concentration delivered by the fa-arg-peuu np carriers had higher cytotoxicity and induced a higher apoptosis percentage against folate receptor (fr)-overexpressed hela or hct116 than arg-peuu nps. |
2017-11-02 |
2023-08-13 |
Not clear |
| Paromita Kundu, Manasi Das, Kalpalata Tripathy, Sanjeeb K Saho. Delivery of Dual Drug Loaded Lipid Based Nanoparticles across the Blood-Brain Barrier Impart Enhanced Neuroprotection in a Rotenone Induced Mouse Model of Parkinson's Disease. ACS chemical neuroscience. vol 7. issue 12. 2017-10-20. PMID:27642670. |
in vitro results demonstrated augmented inhibition of αs protein into oligomers and fibrils, reduced rotenone induced toxicity, oxidative stress, and apoptosis, and activation of autophagic pathway by dual drug loaded nps compared to native counterpart. |
2017-10-20 |
2023-08-13 |
mouse |
| Fei Gao, Jinming Zhang, Chaomei Fu, Xiaoming Xie, Fu Peng, Jieshu You, Hailin Tang, Zhiyu Wang, Peng Li, Jianping Che. iRGD-modified lipid-polymer hybrid nanoparticles loaded with isoliquiritigenin to enhance anti-breast cancer effect and tumor-targeting ability. International journal of nanomedicine. vol 12. 2017-10-16. PMID:28615942. |
compared to free isl and non-irgd-modified counterparts, isl-irgd nps showed higher cytotoxicity and cell apoptosis against the different type of breast cancer cells. |
2017-10-16 |
2023-08-13 |
mouse |
| Sudeshna Mukherjee, Sayan Ghosh, Dipesh Kr Das, Priyanka Chakraborty, Sreetama Choudhury, Payal Gupta, Arghya Adhikary, Sanjit Dey, Sreya Chattopadhya. Gold-conjugated green tea nanoparticles for enhanced anti-tumor activities and hepatoprotection--synthesis, characterization and in vitro evaluation. The Journal of nutritional biochemistry. vol 26. issue 11. 2017-09-25. PMID:26310506. |
these nps significantly decreased nuclear translocation of nf-κb, coupled with decreased phosphorylation of iĸb and down-regulation of nf-κb-dependent anti-apoptotic proteins bcl2 and akt in a dose-dependent manner, triggering onset of apoptosis. |
2017-09-25 |
2023-08-13 |
mouse |
| Yi Cao, Jimin Long, Liangliang Liu, Tong He, Leying Jiang, Chunxue Zhao, Zhen L. A review of endoplasmic reticulum (ER) stress and nanoparticle (NP) exposure. Life sciences. vol 186. 2017-09-19. PMID:28782531. |
meanwhile, nanomedicinal studies also used er stress inducing nps or nps loaded with er stress inducer to selectively induce er stress mediated apoptosis in cancer cells for cancer therapy. |
2017-09-19 |
2023-08-13 |
human |
| Mansour I Almansour, Mosaid A Alferah, Ziad A Shraideh, Bashir M Jarra. Zinc oxide nanoparticles hepatotoxicity: Histological and histochemical study. Environmental toxicology and pharmacology. vol 51. 2017-08-08. PMID:28236584. |
in comparison with the control rats, the following histological and histochemical alterations were demonstrated in the hepatic tissues of rats exposed to zno nps: sinusoidal dilatation, kupffer cells hyperplasia, lobular and portal triads inflammatory cells infiltration, necrosis, hydropic degeneration, hepatocytes apoptosis, anisokaryosis, karyolysis, nuclear membrane irregularity, glycogen content depletion and hemosidrosis. |
2017-08-08 |
2023-08-13 |
human |
| Jing Tian, Shasha Xu, Hongbing Deng, Xinxing Song, Xiujuan Li, Jiajia Chen, Feng Cao, Bin L. Fabrication of self-assembled chitosan-dispersed LDL nanoparticles for drug delivery with a one-step green method. International journal of pharmaceutics. vol 517. issue 1-2. 2017-06-13. PMID:27845214. |
in addition, flow cytometry and terminal-deoxynucleotidyl-transferase-mediated dutp nick-end labeling assay demonstrated that cs-ldl-dox nps induced the apoptosis of cancer cells. |
2017-06-13 |
2023-08-13 |
Not clear |
| Sumeet Kapoor, Dikishi Gupta, Manoj Kumar, Sapna Sharma, Amit K Gupta, M M Misro, Harpal Sing. Intracellular delivery of peptide cargos using polyhydroxybutyrate based biodegradable nanoparticles: Studies on antitumor efficacy of BCL-2 converting peptide, NuBCP-9. International journal of pharmaceutics. vol 511. issue 2. 2017-05-18. PMID:27492021. |
confocal laser microscopy confirmed efficient cellular uptake and induction of apoptosis by peptide loaded nps in a time dependent manner. |
2017-05-18 |
2023-08-13 |
mouse |
| Fangrong Zhang, Xiaoyi Wang, Xiangting Xu, Min Li, Jianping Zhou, Wei Wan. Reconstituted high density lipoprotein mediated targeted co-delivery of HZ08 and paclitaxel enhances the efficacy of paclitaxel in multidrug-resistant MCF-7 breast cancer cells. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. vol 92. 2017-04-06. PMID:27343697. |
results demonstrated that ptx-hz08-rhdl nps significantly enhanced anticancer efficacy in vitro, including higher cytotoxicity and better ability to induce cell apoptosis against both ptx-sensitive and -resistant mcf-7 human breast cancer cell lines (mcf-7 and mcf-7/ptx cells). |
2017-04-06 |
2023-08-13 |
human |
| Suk Ju Jang, In Jun Yang, Clement O Tettey, Ki Mo Kim, Heung Mook Shi. In-vitro anticancer activity of green synthesized silver nanoparticles on MCF-7 human breast cancer cells. Materials science & engineering. C, Materials for biological applications. vol 68. 2017-04-06. PMID:27524038. |
silver nps were found to be significantly toxic to mcf-7 cells via the induction of apoptosis whereas sparing normal immune system (raw 264.7) cells. |
2017-04-06 |
2023-08-13 |
human |
| Fei Gao, Ningjie Ma, Hong Zhou, Qing Wang, Hao Zhang, Pu Wang, Haoli Hou, Huan Wen, Lijia L. Zinc oxide nanoparticles-induced epigenetic change and G2/M arrest are associated with apoptosis in human epidermal keratinocytes. International journal of nanomedicine. vol 11. 2017-03-13. PMID:27570453. |
these findings suggest that the zno nps induced cell cycle arrest at g2/m, which was associated with epigenetic changes and accompanied by p53-bax mitochondrial pathway-mediated apoptosis. |
2017-03-13 |
2023-08-13 |
human |
| Zuojin Liu, Dechao Niu, Junyong Zhang, Wenfeng Zhang, Yuan Yao, Pei Li, Jianping Gon. Amphiphilic core-shell nanoparticles containing dense polyethyleneimine shells for efficient delivery of microRNA to Kupffer cells. International journal of nanomedicine. vol 11. 2017-02-27. PMID:27366061. |
the cell counting kit-8 assay and flow cytometry results showed that the pei@pmma/mirna nps displayed low cytotoxicity and cell apoptosis activity against the kcs. |
2017-02-27 |
2023-08-13 |
Not clear |
| Ying-Ying Wang, Dan-Dan Zhang, Yan-Yan Kong, Luan-Luan Shao, Fen-Yi Zhang, Yu Gao, Xu Mu, Jie Wang, Hao-Fan Li, Shu-Qin Yu, Qian X. CS/PAA@TPGS/PLGA nanoparticles with intracellular pH-sensitive sequential release for delivering drug to the nucleus of MDR cells. Colloids and surfaces. B, Biointerfaces. vol 145. 2017-02-22. PMID:27289313. |
simultaneously, s@l nps enhanced the anticancer effect of the loaded drug by inducing autophagy and apoptosis of mdr cells. |
2017-02-22 |
2023-08-13 |
Not clear |
| M Seifi-Najmi, M Hajivalili, R Safaralizadeh, S Sadreddini, S Esmaeili, R Razavi, M Ahmadi, H Mikaeili, B Baradaran, K Shams-Asenjan, M Yousef. SiRNA/DOX lodeded chitosan based nanoparticles: Development, Characterization and in vitro evaluation on A549 lung cancer cell line. Cellular and molecular biology (Noisy-le-Grand, France). vol 62. issue 11. 2017-02-08. PMID:27755958. |
in addition capability of apoptosis induction and anti-migratory features of formulated nps were analyzed by flowcytometry and wound healing assays. |
2017-02-08 |
2023-08-13 |
Not clear |
| M Seifi-Najmi, M Hajivalili, R Safaralizadeh, S Sadreddini, S Esmaeili, R Razavi, M Ahmadi, H Mikaeili, B Baradaran, K Shams-Asenjan, M Yousef. SiRNA/DOX lodeded chitosan based nanoparticles: Development, Characterization and in vitro evaluation on A549 lung cancer cell line. Cellular and molecular biology (Noisy-le-Grand, France). vol 62. issue 11. 2017-02-08. PMID:27755958. |
nps loaded with dox and sirna were the most efficient drug formulations in a549 cell cytotoxicity, altering of emt markers, apoptosis induction and migration inhibition. |
2017-02-08 |
2023-08-13 |
Not clear |
| Shuhang Liang, Kuo Sun, Yue Wang, Shuying Dong, Cheng Wang, LianXin Liu, YongHui W. Role of Cyt-C/caspases-9,3, Bax/Bcl-2 and the FAS death receptor pathway in apoptosis induced by zinc oxide nanoparticles in human aortic endothelial cells and the protective effect by alpha-lipoic acid. Chemico-biological interactions. vol 258. 2017-01-31. PMID:27544635. |
exposure to zno nps was found to induce apoptosis at 12 h and necrosis after 24 h. |
2017-01-31 |
2023-08-13 |
human |
| Shuhang Liang, Kuo Sun, Yue Wang, Shuying Dong, Cheng Wang, LianXin Liu, YongHui W. Role of Cyt-C/caspases-9,3, Bax/Bcl-2 and the FAS death receptor pathway in apoptosis induced by zinc oxide nanoparticles in human aortic endothelial cells and the protective effect by alpha-lipoic acid. Chemico-biological interactions. vol 258. 2017-01-31. PMID:27544635. |
in addition, the antioxidant la was able to protect haecs from apoptosis induced by zno nps. |
2017-01-31 |
2023-08-13 |
human |
| Zhe Liu, Meng Zhang, Xueying Han, Haiming Xu, Biao Zhang, Qilin Yu, Mingchun L. TiO2 nanoparticles cause cell damage independent of apoptosis and autophagy by impairing the ROS-scavenging system in Pichia pastoris. Chemico-biological interactions. vol 252. 2017-01-26. PMID:27041071. |
results showed that the nps entered cells and had toxicity to this fungus, and their toxicity was attributed to cell wall damage, cell membrane damage, and ros accumulation, but not apoptosis or autophagy. |
2017-01-26 |
2023-08-13 |
Not clear |
| Xiwei Yu, Jiahui Hou, Yijie Shi, Chang Su, Liang Zha. Preparation and characterization of novel chitosan-protamine nanoparticles for nucleus-targeted anticancer drug delivery. International journal of nanomedicine. vol 11. 2017-01-23. PMID:27881917. |
the anticancer effects of nuclear targeted-delivery of drugs in nps were also evaluated by investigating cytotoxicity, cellular uptake mechanism, and cell apoptosis on cells. |
2017-01-23 |
2023-08-13 |
Not clear |
| Xiwei Yu, Jiahui Hou, Yijie Shi, Chang Su, Liang Zha. Preparation and characterization of novel chitosan-protamine nanoparticles for nucleus-targeted anticancer drug delivery. International journal of nanomedicine. vol 11. 2017-01-23. PMID:27881917. |
compared with free 5-fu and 5-fu-loaded chitosan nps, treatment of a549 cells and hela cells with 5-fu-loaded chitosan-protamine nps showed the highest cytotoxicity and further induced the significant apoptosis of cells. |
2017-01-23 |
2023-08-13 |
Not clear |