| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Fashui Hong, Xiaoyang Zhao, Ming Chen, Yingjun Zhou, Yuguan Ze, Ling Wang, Yajing Wang, Yushuang Ge, Qi Zhang, Lingqun Y. TiO2 nanoparticles-induced apoptosis of primary cultured Sertoli cells of mice. Journal of biomedical materials research. Part A. vol 104. issue 1. 2016-09-26. PMID:26238530. |
results showed that tio2 nps exposure from 5 to 30 μg/ml resulted in reduction of cell viability, lactate dehydrogenase release, and induction of apoptosis or death on sertoli cells. |
2016-09-26 |
2023-08-13 |
mouse |
| Manu Dalela, T G Shrivastav, Surender Kharbanda, Harpal Sing. pH-Sensitive Biocompatible Nanoparticles of Paclitaxel-Conjugated Poly(styrene-co-maleic acid) for Anticancer Drug Delivery in Solid Tumors of Syngeneic Mice. ACS applied materials & interfaces. vol 7. issue 48. 2016-09-26. PMID:26528585. |
confocal microscopy, western blotting, and flow cytometry results further supported that the cellular uptake and apoptosis of cancer cells with psmac-ptx nps. |
2016-09-26 |
2023-08-13 |
mouse |
| Manu Dalela, T G Shrivastav, Surender Kharbanda, Harpal Sing. pH-Sensitive Biocompatible Nanoparticles of Paclitaxel-Conjugated Poly(styrene-co-maleic acid) for Anticancer Drug Delivery in Solid Tumors of Syngeneic Mice. ACS applied materials & interfaces. vol 7. issue 48. 2016-09-26. PMID:26528585. |
administration of psmac-ptx nps showed significant tumor growth inhibition with improved apoptosis effects in vivo on ehrlich ascites tumor (eat)-bearing balb/c syngeneic mice in comparison with taxol, without showing any cytotoxicity. |
2016-09-26 |
2023-08-13 |
mouse |
| Paulo Emilio Feuser, Pamela Cristina Gaspar, Amanda Virtuoso Jacques, Antônio Claudio Tedesco, Maria Claudia Dos Santos Silva, Eduardo Ricci-Júnior, Claudia Sayer, Pedro Henrique Hermes de Araúj. Synthesis of ZnPc loaded poly(methyl methacrylate) nanoparticles via miniemulsion polymerization for photodynamic therapy in leukemic cells. Materials science & engineering. C, Materials for biological applications. vol 60. 2016-09-26. PMID:26706552. |
the results from fluorescence microscopy (eb/oa) and dna fragmentation suggest that the znpc loaded pmma nps induced cell death by apoptosis. |
2016-09-26 |
2023-08-13 |
human |
| Jun-Hyung Kim, Myeong Seon Jeong, Dong-Yung Kim, Song Her, Myung-Bok Wi. Zinc oxide nanoparticles induce lipoxygenase-mediated apoptosis and necrosis in human neuroblastoma SH-SY5Y cells. Neurochemistry international. vol 90. 2016-09-20. PMID:26364578. |
these results suggest that zno nps induce apoptosis via the pi3k/akt/caspase-3/7 pathway and necrosis by lox-mediated ros production elevation. |
2016-09-20 |
2023-08-13 |
human |
| Mohd Javed Akhtar, Hisham A Alhadlaq, Sudhir Kumar, Salman A Alrokayan, Maqusood Ahame. Selective cancer-killing ability of metal-based nanoparticles: implications for cancer therapy. Archives of toxicology. vol 89. issue 11. 2016-09-14. PMID:26223318. |
many in vitro and in vivo reports suggest that certain metal-based nps are able to induce apoptosis and autophagy in cancer cells at specific concentrations that are not significantly toxic to non-cancerous cells. |
2016-09-14 |
2023-08-13 |
Not clear |
| C Ganesh Kumar, Y Poornachandra, Cheemalamarri Chandrasekha. Green synthesis of bacterial mediated anti-proliferative gold nanoparticles: inducing mitotic arrest (G2/M phase) and apoptosis (intrinsic pathway). Nanoscale. vol 7. issue 44. 2016-09-07. PMID:26503300. |
mechanistic studies, such as ros, mmp, cyt-c, gsh, caspases 9, 8 and 3 activation and the annexin v-fitc staining, along with the above parameters tested provided sufficient evidence that the b-au nps induced apoptosis through the intrinsic pathway. |
2016-09-07 |
2023-08-13 |
human |
| Anne-Sophie Guedj, Arnold J Kell, Michael Barnes, Sandra Stals, David Gonçalves, Denis Girard, Carole Lavign. Preparation, characterization, and safety evaluation of poly(lactide-co-glycolide) nanoparticles for protein delivery into macrophages. International journal of nanomedicine. vol 10. 2016-08-31. PMID:26445538. |
plga nps were not cytotoxic for thp-1 mdm cells, did not modulate neutrophil apoptosis in vitro, and did not show inflammatory effect in vivo in the murine air pouch model of acute inflammation. |
2016-08-31 |
2023-08-13 |
human |
| Liang Zhao, Hongdan Li, Yijie Shi, Guan Wang, Liwei Liu, Chang Su, Rongjian S. Nanoparticles inhibit cancer cell invasion and enhance antitumor efficiency by targeted drug delivery via cell surface-related GRP78. International journal of nanomedicine. vol 10. 2016-08-19. PMID:25565817. |
our new findings suggest that mab grp78-nps could enhance drug accumulation by effectively transporting nps into cell surface grp78-overexpressed human hepatocellular carcinoma cells and then inhibit cell proliferation and viability and induce cell apoptosis by regulating caspase-3. |
2016-08-19 |
2023-08-13 |
human |
| Jung-Hwa Oh, Mi-Young Son, Mi-Sun Choi, Soojin Kim, A-Young Choi, Hyang-Ae Lee, Ki-Suk Kim, Janghwan Kim, Chang Woo Song, Seokjoo Yoo. Integrative analysis of genes and miRNA alterations in human embryonic stem cells-derived neural cells after exposure to silver nanoparticles. Toxicology and applied pharmacology. vol 299. 2016-08-18. PMID:26551752. |
in addition, ag nps induced cell cycle arrest and apoptosis following a significant increase in oxidative stress in these cells. |
2016-08-18 |
2023-08-13 |
human |
| Cuiping Yang, Fei Xiong, Jun Dou, Jun Xue, Xi Zhan, Fangfang Shi, Miao Li, Songyan Wu, Shouhua Luo, Tianzhu Zhang, Yu Zhang, Ji Ming, Ning G. Target therapy of multiple myeloma by PTX-NPs and ABCG2 antibody in a mouse xenograft model. Oncotarget. vol 6. issue 29. 2016-08-16. PMID:26314844. |
all the treated mice showed decrease in bone lesions, renal damages and anemia but increase in apoptosis compared with the mice treated with nps only. |
2016-08-16 |
2023-08-13 |
mouse |
| Lei Sheng, Ling Wang, Mingyu Su, Xiaoyang Zhao, Renping Hu, Xiaohong Yu, Jie Hong, Dong Liu, Bingqing Xu, Yunting Zhu, Han Wang, Fashui Hon. Mechanism of TiO2 nanoparticle-induced neurotoxicity in zebrafish (Danio rerio). Environmental toxicology. vol 31. issue 2. 2016-08-15. PMID:25059219. |
our data indicated that spatial recognition memory and levels of norepinephrine, dopamine, and 5-hydroxytryptamine were significantly decreased and no levels were markedly elevated, and over proliferation of glial cells, neuron apoptosis, and tio2 np aggregation were observed after low dose exposures of tio2 nps. |
2016-08-15 |
2023-08-13 |
zebrafish |
| Fashui Hong, Yajing Wang, Yingjun Zhou, Qi Zhang, Yushuang Ge, Ming Chen, Jie Hong, Ling Wan. Exposure to TiO2 Nanoparticles Induces Immunological Dysfunction in Mouse Testitis. Journal of agricultural and food chemistry. vol 64. issue 1. 2016-08-11. PMID:26720763. |
the results showed that male mice exhibited significant reduction of fertility, infiltration of inflammatory cells, rarefaction, apoptosis, and/or necrosis of spermatogenic cells and sertoli cells due to tio2 nps. |
2016-08-11 |
2023-08-13 |
mouse |
| Fengqian Chen, Jinming Zhang, Lu Wang, Yitao Wang, Meiwan Che. Tumor pH(e)-triggered charge-reversal and redox-responsive nanoparticles for docetaxel delivery in hepatocellular carcinoma treatment. Nanoscale. vol 7. issue 38. 2016-07-25. PMID:26355843. |
the positively charged nps exhibited a stronger inhibitory effect on cell proliferation, promoted cell cycle arrest in the g2/m phase, and increased the rate of apoptosis. |
2016-07-25 |
2023-08-13 |
mouse |
| De-Sheng Liang, Hai-Tao Su, Yu-Jie Liu, Ai-Ting Wang, Xian-Rong Q. Tumor-specific penetrating peptides-functionalized hyaluronic acid-d-α-tocopheryl succinate based nanoparticles for multi-task delivery to invasive cancers. Biomaterials. vol 71. 2016-07-12. PMID:26310359. |
in vitro studies demonstrated that the tlpts/hats nps exhibited enhanced intracellular delivery and much better anti-invasion ability, cytotoxicity, and apoptosis against both invasive pc-3 and mda-mb-231 cells as compared to the non-tlyp-1-functionalized hats nps. |
2016-07-12 |
2023-08-13 |
mouse |
| Hongmei Wang, Xin Zhao, Caihong Guo, Dunqiang Ren, Yandong Zhao, Wei Xiao, Wenjie Jia. Aptamer-Dendrimer Bioconjugates for Targeted Delivery of miR-34a Expressing Plasmid and Antitumor Effects in Non-Small Cell Lung Cancer Cells. PloS one. vol 10. issue 9. 2016-06-17. PMID:26406332. |
in addition, we revealed pam-ap/pmir-34a nps significantly inhibited cell growth, migration, invasion and induced apoptosis of lung cancer cells compared with non-targeted nps. |
2016-06-17 |
2023-08-13 |
Not clear |
| Bin Song, YanLi Zhang, Jia Liu, XiaoLi Feng, Ting Zhou, LongQuan Sha. Is Neurotoxicity of Metallic Nanoparticles the Cascades of Oxidative Stress? Nanoscale research letters. vol 11. issue 1. 2016-06-14. PMID:27295259. |
oxidative stress (os), apoptosis, and the inflammatory response are believed to be the main mechanisms underlying the neurotoxicity of metallic nps. |
2016-06-14 |
2023-08-13 |
human |
| Elisabetta Cenni, Sofia Avnet, Donatella Granchi, Caterina Fotia, Manuela Salerno, Dorotea Micieli, Maria Grazia Sarpietro, Rosario Pignatello, Francesco Castelli, Nicola Baldin. The effect of poly(d,l-lactide-co-glycolide)-alendronate conjugate nanoparticles on human osteoclast precursors. Journal of biomaterials science. Polymer edition. vol 23. issue 10. 2016-05-26. PMID:21781381. |
to show if ale retained the antiosteoclastic properties after the conjugation with plga and the production of nps, we treated human osteoclasts, derived from circulating precursors, with plga-ale nps and compared the effects on actin ring generation, apoptosis and type-i collagen degradation with those of free ale and with nps made of pure plga. |
2016-05-26 |
2023-08-12 |
human |
| Elisabetta Cenni, Sofia Avnet, Donatella Granchi, Caterina Fotia, Manuela Salerno, Dorotea Micieli, Maria Grazia Sarpietro, Rosario Pignatello, Francesco Castelli, Nicola Baldin. The effect of poly(d,l-lactide-co-glycolide)-alendronate conjugate nanoparticles on human osteoclast precursors. Journal of biomaterials science. Polymer edition. vol 23. issue 10. 2016-05-26. PMID:21781381. |
plga-ale nps disrupted actin ring, induced apoptosis and inhibited collagen degradation. |
2016-05-26 |
2023-08-12 |
human |
| Ester Boix-Garriga, Pilar Acedo, Ana Casadó, Angeles Villanueva, Juan Carlos Stockert, Magdalena Cañete, Margarita Mora, Maria Lluïsa Sagristá, Santi Nonel. Poly(D, L-lactide-co-glycolide) nanoparticles as delivery agents for photodynamic therapy: enhancing singlet oxygen release and photototoxicity by surface PEG coating. Nanotechnology. vol 26. issue 36. 2016-05-23. PMID:26293792. |
plga nps are internalized by endocytosis, deliver their cargo to lysosomes and induce cell death by apoptosis upon exposure to light. |
2016-05-23 |
2023-08-13 |
Not clear |