| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Min-Chao Liu, Bing Liu, Xiang-Yu Sun, Hui-Chao Lin, Jia-Zheng Lu, Shu-Fang Jin, Si-Qi Yan, Yan-Yu Li, Ping Zha. Core/Shell Structured Fe₃O₄@TiO₂-DNM Nanospheres as Multifunctional Anticancer Platform: Chemotherapy and Photodynamic Therapy Research. Journal of nanoscience and nanotechnology. vol 18. issue 7. 2018-08-06. PMID:29442618. |
the cell apoptotic results revealed that the apoptosis induced by the fe3o4@tio2-dnm nps was in the early stage. |
2018-08-06 |
2023-08-13 |
Not clear |
| Vinay Kumar Tripathi, Allur Subramaniyan Sivakumar, Anupam Dhasmana, Inho Hwan. Crosstalk Between Co-Cultured 3T3-L1 and C2C12 Cells After the Exposure of Nano-Titanium Dioxide. Journal of nanoscience and nanotechnology. vol 18. issue 6. 2018-08-06. PMID:29442721. |
additionally, real-time pcr data analysis shown an increased in the expression of p53, bax, caspase-9, caspase-3 and decreased the level of bcl-2, by this means specifying that apoptosis induced by tio2 nps occurs via the caspase-dependent pathway. |
2018-08-06 |
2023-08-13 |
Not clear |
| Heng Zhang, Yu Jiang, XiaoLing Ni, LongXia Chen, Min Wu, Jing Liu, Bo Yang, Xu Shan, LingLin Yang, Juan Fan, Yue Chen, JingBo Wu, ShaoZhi F. Glycyrrhetinic Acid-Modified Norcantharidin Nanoparticles for Active Targeted Therapy of Hepatocellular Carcinoma. Journal of biomedical nanotechnology. vol 14. issue 1. 2018-07-31. PMID:29463369. |
determination of cell apoptosis and cell cycle phase showed that at nps resulted in increased cell apoptosis and a distinct increase in the g2 phase (65.30 ± 3.52%, p < 0.01) and s phase (46.39 ± 1.39%, p < 0.01). |
2018-07-31 |
2023-08-13 |
mouse |
| Sivakumar Allur Subramaniyan, Sunirmal Sheet, Mohanraj Vinothkannan, Dong Jin Yoo, Yang Soo Lee, Shah Ahmed Belal, Kwan Seob Shi. One-Pot Facile Synthesis of Pt Nanoparticles Using Cultural Filtrate of Microgravity Simulated Grown Journal of nanoscience and nanotechnology. vol 18. issue 5. 2018-07-30. PMID:29442810. |
moreover, the protein expression of both (i) apoptosis related proteins such as cas-3 and cas-9, (ii) inflammatory response proteins such as tnf-α, tgf-β and nf-κb were significantly upregulated in mg-pt nps treated cells than ng-pt nps treated cells. |
2018-07-30 |
2023-08-13 |
Not clear |
| Sivakumar Allur Subramaniyan, Sunirmal Sheet, Mohanraj Vinothkannan, Dong Jin Yoo, Yang Soo Lee, Shah Ahmed Belal, Kwan Seob Shi. One-Pot Facile Synthesis of Pt Nanoparticles Using Cultural Filtrate of Microgravity Simulated Grown Journal of nanoscience and nanotechnology. vol 18. issue 5. 2018-07-30. PMID:29442810. |
uptake and intracellular localization of mg-pt nps caused by accumulation of autophagosomes in c2c12 cells and bacterial cells, indicate that synthesized mg-pt nps enable for the swift cell apoptosis than ng-pt nps. |
2018-07-30 |
2023-08-13 |
Not clear |
| Ru Yuan, Huanli Xu, Xiaohui Liu, Ye Tian, Cong Li, Xiaoliang Chen, Shuonan Su, Ilana Perelshtein, Aharon Gedanken, Xiukun Li. Zinc-Doped Copper Oxide Nanocomposites Inhibit the Growth of Human Cancer Cells through Reactive Oxygen Species-Mediated NF-κB Activations. ACS applied materials & interfaces. vol 8. issue 46. 2018-07-18. PMID:27791350. |
hoechst 33342 staining and fitc-annexin v/pi staining showed that nzn-cuo nps could induce cell apoptosis in a dose dependent manner. |
2018-07-18 |
2023-08-13 |
human |
| Pawan K Mishra, Harshita Mishra, Adam Ekielski, Sushama Talegaonkar, Bhuvaneshwar Vaidy. Zinc oxide nanoparticles: a promising nanomaterial for biomedical applications. Drug discovery today. vol 22. issue 12. 2018-07-18. PMID:28847758. |
these activities are associated with the ability of zno nps to generate reactive oxygen species (ros) and induce apoptosis. |
2018-07-18 |
2023-08-13 |
Not clear |
| Yudong Song, Cui Tang, Chunhua Yi. Enhanced antitumor efficacy of arginine modified amphiphilic nanoparticles co-delivering doxorubicin and iSur-pDNA via the multiple synergistic effect. Biomaterials. vol 150. 2018-06-15. PMID:29028548. |
particularly, blank tas nps were selectively be toxic to tumor cells as evidenced by their capabilities to inhibit proliferation and induce apoptosis of tumor cells. |
2018-06-15 |
2023-08-13 |
mouse |
| Richard Nuccitelli, Amanda McDaniel, Snjezana Anand, John Cha, Zachary Mallon, Jon Casey Berridge, Darrin Uecke. Nano-Pulse Stimulation is a physical modality that can trigger immunogenic tumor cell death. Journal for immunotherapy of cancer. vol 5. 2018-06-08. PMID:28428881. |
here we present evidence that nps stimulates both caspase 3/7 activation indicative of apoptosis, as well as the emission of three critical damps: ecto-calreticulin (crt), atp and hmgb1. |
2018-06-08 |
2023-08-13 |
Not clear |
| Yang Xiong, Yi Zhao, Lei Miao, C Michael Lin, Leaf Huan. Co-delivery of polymeric metformin and cisplatin by self-assembled core-membrane nanoparticles to treat non-small cell lung cancer. Journal of controlled release : official journal of the Controlled Release Society. vol 244. issue Pt A. 2018-05-24. PMID:27840166. |
cddp delivered with nanoparticles (nps) exhibited significantly increased tumor accumulation over free cddp and suppressed tumor growth through apoptosis in nsclc h460 tumor-bearing mice without nephrotoxicity. |
2018-05-24 |
2023-08-13 |
mouse |
| Yuan Zhao, Meng-Lei Huan, Miao Liu, Ying Cheng, Yang Sun, Han Cui, Dao-Zhou Liu, Qi-Bing Mei, Si-Yuan Zho. Doxorubicin and resveratrol co-delivery nanoparticle to overcome doxorubicin resistance. Scientific reports. vol 6. 2018-05-02. PMID:27731405. |
furthermore, dox/res-loaded nps could overcome dox resistance by inhibiting the expression of drug resistance-related protein such as p-gp, mrp-1 and bcrp, and induce apoptosis through down-regulating the expression of nf-κb and bcl-2. |
2018-05-02 |
2023-08-13 |
mouse |
| Allur Subramaniyan Sivakumar, Chandran Krishnaraj, Sunirmal Sheet, Dileep Reddy Rampa, Da Rae Kang, Shah Ahmed Belal, Abhay Kumar, In Ho Hwang, Soon-Il Yun, Yang Soo Lee, Kwan Seob Shi. Interaction of silver and gold nanoparticles in mammalian cancer: as real topical bullet for wound healing- A comparative study. In vitro cellular & developmental biology. Animal. vol 53. issue 7. 2018-04-09. PMID:28462492. |
the intracellular localization of ag and au nps in ht-1080 cells and their subsequent effect on apoptosis and necrosis were analyzed by flow cytometry while the mode of interaction was established by scanning electron microscopy under field emission mode and by bio-transmission electron microscopy. |
2018-04-09 |
2023-08-13 |
mouse |
| Allur Subramaniyan Sivakumar, Chandran Krishnaraj, Sunirmal Sheet, Dileep Reddy Rampa, Da Rae Kang, Shah Ahmed Belal, Abhay Kumar, In Ho Hwang, Soon-Il Yun, Yang Soo Lee, Kwan Seob Shi. Interaction of silver and gold nanoparticles in mammalian cancer: as real topical bullet for wound healing- A comparative study. In vitro cellular & developmental biology. Animal. vol 53. issue 7. 2018-04-09. PMID:28462492. |
these methods of analysis clearly revealed that the ag and au nps have easily entered and accumulated into the cytosol and nucleus, resulting in activation of inflammatory and apoptosis pathways, which in turn cause damage in dna. |
2018-04-09 |
2023-08-13 |
mouse |
| Yang Li, Guihua Liu, Jinyuan Ma, Jinyan Lin, Huirong Lin, Guanghao Su, Dengyue Chen, Shefang Ye, Xiaoyuan Chen, Xuan Zhu, Zhenqing Ho. Chemotherapeutic drug-photothermal agent co-self-assembling nanoparticles for near-infrared fluorescence and photoacoustic dual-modal imaging-guided chemo-photothermal synergistic therapy. Journal of controlled release : official journal of the Controlled Release Society. vol 258. 2018-03-29. PMID:28501673. |
moreover, in comparison with individual chemotherapy or ptt, the combinational chemo-ptt therapy of icg-epi nps with nir laser irradiation synergistically induced apoptosis and death of cancer cells in vitro, and showed synergistic chemo-ptt efficiency in vivo as evidenced by highly efficient tumor ablation. |
2018-03-29 |
2023-08-13 |
Not clear |
| Salma N Tammam, Hassan M E Azzazy, Alf Lamprech. The effect of nanoparticle size and NLS density on nuclear targeting in cancer and normal cells; impaired nuclear import and aberrant nanoparticle intracellular trafficking in glioma. Journal of controlled release : official journal of the Controlled Release Society. vol 253. 2018-03-21. PMID:28254629. |
however, to evade apoptosis and stimulate tumor growth cancer cells are capable of manipulating the nuclear-cytoplasmic transport on many levels, making nps that are capable of nuclear targeting in normal cells incapable of doing so in cancer. |
2018-03-21 |
2023-08-13 |
human |
| Fatemeh Ahmadi, Maryam Ghasemi-Kasman, Shahram Ghasemi, Maryam Gholamitabar Tabari, Roghayeh Pourbagher, Sohrab Kazemi, Ali Alinejad-Mi. Induction of apoptosis in HeLa cancer cells by an ultrasonic-mediated synthesis of curcumin-loaded chitosan-alginate-STPP nanoparticles. International journal of nanomedicine. vol 12. 2018-03-19. PMID:29238191. |
collectively, our results suggest that curcumin-loaded nps significantly suppressed proliferation and promoted the induction of apoptosis in human cervical epithelioid carcinoma cancer cells, which might be regarded as an effective alternative strategy for cancer therapy. |
2018-03-19 |
2023-08-13 |
human |
| Elanur Aydın, Hasan Türkez, Fazıl Hacımüftüoğlu, Abdulgani Tatar, Fatime Geyikoğl. Molecular genetic and biochemical responses in human airway epithelial cell cultures exposed to titanium nanoparticles in vitro. Journal of biomedical materials research. Part A. vol 105. issue 7. 2018-03-09. PMID:28028929. |
determining and analyzing the gene expression profiles of hpaepic and hppc cells, titanium nps showed more changes in genes related to dna damage or repair, oxidative stress, and apoptosis. |
2018-03-09 |
2023-08-13 |
human |
| Ding-Ping Bai, Xi-Feng Zhang, Guo-Liang Zhang, Yi-Fan Huang, Sangiliyandi Gurunatha. Zinc oxide nanoparticles induce apoptosis and autophagy in human ovarian cancer cells. International journal of nanomedicine. vol 12. 2018-03-08. PMID:28919752. |
therefore, this study was undertaken to investigate the effect of zno nps on cytotoxicity, apoptosis, and autophagy in human ovarian cancer cells (skov3). |
2018-03-08 |
2023-08-13 |
human |
| Zhilei Mao, Mengmeng Yao, Bo Xu, Xiaoli Ji, Hua Jiang, Xiumei Han, Qiusha Tang, Zuomin Zhou, Rui Chen, Xiaobo Li, Yankai Xi. Cytoskeletons of Two Reproductive Germ Cell Lines Response Differently to Titanium Dioxide Nanoparticles Mediating Vary Reproductive Toxicity. Journal of biomedical nanotechnology. vol 13. issue 4. 2018-02-23. PMID:29384604. |
our results showed that tio2 nps did not affect cell viability but induced cell apoptosis of both gc-2 and tm4 cells up to 100 μg/ml. |
2018-02-23 |
2023-08-13 |
Not clear |
| Zhilei Mao, Mengmeng Yao, Bo Xu, Xiaoli Ji, Hua Jiang, Xiumei Han, Qiusha Tang, Zuomin Zhou, Rui Chen, Xiaobo Li, Yankai Xi. Cytoskeletons of Two Reproductive Germ Cell Lines Response Differently to Titanium Dioxide Nanoparticles Mediating Vary Reproductive Toxicity. Journal of biomedical nanotechnology. vol 13. issue 4. 2018-02-23. PMID:29384604. |
totally tio2 nps is toxic to gc-2 cells by inducing cell apoptosis, disturbing microtubule arrangement and microtubule dynamic, and impairing cell migration ability. |
2018-02-23 |
2023-08-13 |
Not clear |