| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shumei Wang, Liyun Qiu, Haiyan Song, Ningning Dan. NPS - 2143 (hydrochloride) inhibits melanoma cancer cell proliferation and induces autophagy and apoptosis. Medecine sciences : M/S. vol 34 Focus issue F1. 2019-02-13. PMID:30403181. |
nps - 2143 (hydrochloride) inhibits melanoma cancer cell proliferation and induces autophagy and apoptosis. |
2019-02-13 |
2023-08-13 |
human |
| Ying-Yi Chen, Yu-Jung Lin, Wei-Ting Huang, Chin-Chuan Hung, Hui-Yi Lin, Yu-Chen Tu, Dean-Mo Liu, Shou-Jen Lan, Ming-Jyh She. Demethoxycurcumin-Loaded Chitosan Nanoparticle Downregulates DNA Repair Pathway to Improve Cisplatin-Induced Apoptosis in Non-Small Cell Lung Cancer. Molecules (Basel, Switzerland). vol 23. issue 12. 2019-02-12. PMID:30563166. |
we aimed to understand whether dmc-chc nps efficiently potentiate cisplatin-induced apoptosis through downregulation of ercc1 in nsclc. |
2019-02-12 |
2023-08-13 |
Not clear |
| Qian Guo, Zengyan Chang, Naveed Ullah Khan, Tongtong Miao, Xiufeng Ju, Huaxiang Feng, Lei Zhang, Zhenglong Sun, Hui Li, Liang Ha. Nanosizing Noncrystalline and Porous Silica Material-Naturally Occurring Opal Shale for Systemic Tumor Targeting Drug Delivery. ACS applied materials & interfaces. vol 10. issue 31. 2019-02-11. PMID:30020771. |
interestingly, os nps possessed strong binding with the nuclear envelope, which can be beneficial to the nucleus localization and apoptosis inducing of loaded dox. |
2019-02-11 |
2023-08-13 |
Not clear |
| Nasim Rahmani Kukia, Yousef Rasmi, Ardeshir Abbasi, Nana Koshoridze, Alireza Shirpoor, George Burjanadze, Ehsan Saboor. Bio-Effects of TiO2 Nanoparticles on Human Colorectal Cancer and Umbilical Vein Endothelial Cell Lines Asian Pacific journal of cancer prevention : APJCP. vol 19. issue 10. 2019-02-06. PMID:30361551. |
results: exposure to increasing concentrations of tio2 nps enhanced overall cell survivalof hct116 cells and reduced the bcl-2 and caspase 3 expression while the ratio of bax/bcl-2 was down-regulated.tio2 nps at 400 and 50 μg/ml concentrations suppressed cell proliferation and induced apoptosis of ht29 cells andalso up-regulated p53 and bax at the mrna level, enhanced the bax/bcl-2 ratio and eventually up-regulated caspase3 mrna. |
2019-02-06 |
2023-08-13 |
human |
| N Sanoj Rejinold, Jisang Yoo, Sangyong Jon, Yeu-Chun Ki. Curcumin as a Novel Nanocarrier System for Doxorubicin Delivery to MDR Cancer Cells: In Vitro and In Vivo Evaluation. ACS applied materials & interfaces. vol 10. issue 34. 2019-02-04. PMID:30064206. |
the developed peg-coated crc/dox nanoparticles (nps) (peg-crc/dox nps) were well localized within the resistant cancer cells inducing apoptosis confirmed by flow cytometry and dna fragmentation assays. |
2019-02-04 |
2023-08-13 |
Not clear |
| Ruolan Wang, Bin Song, Junrong Wu, Yanli Zhang, Aijie Chen, Longquan Sha. Potential adverse effects of nanoparticles on the reproductive system. International journal of nanomedicine. vol 13. 2019-02-04. PMID:30587973. |
previous studies have shown that nps can increase inflammation, oxidative stress, and apoptosis and induce ros, causing damage at the molecular and genetic levels which results in cytotoxicity. |
2019-02-04 |
2023-08-13 |
Not clear |
| Hyungjoo Kim, Sunhwa Oh, Myung Chan Gye, Incheol Shi. Comparative toxicological evaluation of nonylphenol and nonylphenol polyethoxylates using human keratinocytes. Drug and chemical toxicology. vol 41. issue 4. 2019-01-30. PMID:29124983. |
nps and npeos also induced apoptosis and dna damage as shown by the activation of poly(adp-ribose) polymerase, caspase-3, and histone h2a.x. |
2019-01-30 |
2023-08-13 |
human |
| Yingming Sun, Hongtao Miao, Shijing Ma, Lei Zhang, Chengcheng You, Fang Tang, Cui Yang, Xiaoli Tian, Feng Wang, Yuan Luo, Xiangjie Lin, Hui Wang, Chunyang Li, Zhijun Li, Hongnv Yu, Xuefeng Liu, Yu Xiao, Yan Gong, Junhong Zhang, Hong Quan, Conghua Xi. FePt-Cys nanoparticles induce ROS-dependent cell toxicity, and enhance chemo-radiation sensitivity of NSCLC cells in vivo and in vitro. Cancer letters. vol 418. 2019-01-30. PMID:29331422. |
in the in vitro study, fept-cys nps induced a reactive oxygen species (ros) burst, which suppressed the antioxidant protein expression and induced cell apoptosis. |
2019-01-30 |
2023-08-13 |
Not clear |
| Yating Xiao, Jing Liu, Mengyu Guo, Huige Zhou, Jun Jin, Jiaming Liu, Ying Liu, Zhanjun Zhang, Chunying Che. Synergistic combination chemotherapy using carrier-free celastrol and doxorubicin nanocrystals for overcoming drug resistance. Nanoscale. vol 10. issue 26. 2019-01-30. PMID:29943786. |
these spherical cst/dox nps can improve the water-solubility of cst, reduce the dosage of dox, and therefore significantly enhance cellular drug accumulation by activating heat shock factor 1 (hsf-1) and inhibiting nf-κb to depress p-gp expression, which results in apoptosis and autophagy of dox resistant cells through the ros/jnk signaling pathway. |
2019-01-30 |
2023-08-13 |
Not clear |
| Xing Chen, Xiang Ling, Lili Zhao, Fei Xiong, Geoffrey Hollett, Yang Kang, Austin Barrett, Jun W. Biomimetic Shells Endow Sub-50 nm Nanoparticles with Ultrahigh Paclitaxel Payloads for Specific and Robust Chemotherapy. ACS applied materials & interfaces. vol 10. issue 40. 2019-01-23. PMID:30203956. |
in vitro results showed that after being trafficked through caveolae-mediated endocytosis, app1i@e nps successfully escaped from endo-/lysosomes and then rapidly released cargos in the acidic cytosol, which continued to enhance cytotoxicity by mitochondrial control of apoptosis and suppression of microtubule dynamics. |
2019-01-23 |
2023-08-13 |
Not clear |
| Xiaoli Cai, Yanan Luo, Yang Song, Dong Liu, Hongye Yan, He Li, Dan Du, Chengzhou Zhu, Yuehe Li. Integrating in situ formation of nanozymes with three-dimensional dendritic mesoporous silica nanospheres for hypoxia-overcoming photodynamic therapy. Nanoscale. vol 10. issue 48. 2018-12-26. PMID:30500027. |
in a combination of the peroxidase-like pt nps with mitochondria-targeting ability of tpp, a reactive oxygen species (ros) burst in the mitochondria was achieved and resulted in the cell apoptosis. |
2018-12-26 |
2023-08-13 |
Not clear |
| Mahaveer P Purohit, Neeraj K Verma, Aditya K Kar, Amrita Singh, Debabrata Ghosh, Satyakam Patnai. Inhibition of Thioredoxin Reductase by Targeted Selenopolymeric Nanocarriers Synergizes the Therapeutic Efficacy of Doxorubicin in MCF7 Human Breast Cancer Cells. ACS applied materials & interfaces. vol 9. issue 42. 2018-12-19. PMID:28945070. |
detailed molecular studies on mcf7 cells also established that upon exposure to se@cmha-dox nps, mcf7 cells endure g2/m cell cycle arrest and p53-mediated caspase-independent apoptosis. |
2018-12-19 |
2023-08-13 |
human |
| Xiang Ling, Xing Chen, Imogen A Riddell, Wei Tao, Junqing Wang, Geoffrey Hollett, Stephen J Lippard, Omid C Farokhzad, Jinjun Shi, Jun W. Glutathione-Scavenging Poly(disulfide amide) Nanoparticles for the Effective Delivery of Pt(IV) Prodrugs and Reversal of Cisplatin Resistance. Nano letters. vol 18. issue 7. 2018-12-14. PMID:29902013. |
following systematic screening, the optimized nps (referred to as cp5 nps) showed a small particle size (76.2 nm), high loading of pt(iv) prodrugs (15.50% pt), a sharp response to gsh, the rapid release of platinum (pt) ions, and notable apoptosis of cisplatin-resistant a2780cis cells. |
2018-12-14 |
2023-08-13 |
Not clear |
| Elham Ahmadian, Solmaz Maleki Dizaj, Elaheh Rahimpour, Amir Hasanzadeh, Aziz Eftekhari, Hasan Hosain Zadegan, Jamal Halajzadeh, Hale Ahmadia. Effect of silver nanoparticles in the induction of apoptosis on human hepatocellular carcinoma (HepG2) cell line. Materials science & engineering. C, Materials for biological applications. vol 93. 2018-12-12. PMID:30274079. |
ag nps cytotoxicity was associated with induction of ros and cell apoptosis in hepg2 cell line. |
2018-12-12 |
2023-08-13 |
human |
| N Sanoj Rejinold, Yunho Han, Jisang Yoo, Hae Yong Seok, Ji Ho Park, Yeu-Chun Ki. Evaluation of cell penetrating peptide coated Mn:ZnS nanoparticles for paclitaxel delivery to cancer cells. Scientific reports. vol 8. issue 1. 2018-12-11. PMID:29382898. |
the developed ptx loaded mn:zns nps with different cpps (pen, pvec and r9) showed enhanced anti-cancer effect compared to bare ptx, which has been validated by mtt assay followed by apoptosis assay and dna fragmentation analysis. |
2018-12-11 |
2023-08-13 |
Not clear |
| Qian Lv, Meng-Yue Gao, Zi-He Cheng, Qiao Chen, Ai-Guo Shen, Ji-Ming H. Rational synthesis of hollow cubic CuS@Spiky Au core-shell nanoparticles for enhanced photothermal and SERS effects. Chemical communications (Cambridge, England). vol 54. issue 95. 2018-11-27. PMID:30426112. |
hollow cubic cus@spiky au core-shell nanoparticles (nps) were rationally synthesized both for guided highly efficient damage to cancer cells by the photothermal effect and for the real-time monitoring of biochemical responses during cellular apoptosis, totally based on label-free sers intracellular imaging. |
2018-11-27 |
2023-08-13 |
Not clear |
| Giovanna Gomes Lara, Gracielle Ferreira Andrade, Marcelo Fernandes Cipreste, Wellington Marcos da Silva, Pedro Lana Gastelois, Dawidson Assis Gomes, Marcelo Coutinho de Miranda, Waldemar Augusto de Almeida Macedo, Maria Jose Neves, Edésia Martins Barros de Sous. Protection of normal cells from irradiation bystander effects by silica-flufenamic acid nanoparticles. Journal of materials science. Materials in medicine. vol 29. issue 8. 2018-11-26. PMID:30074096. |
our results show that mcm-41 and functionalized samples have high biocompatibility with mcr-5 and hela cells, and most importantly, the ffa delivered by these nps was able to halt apoptosis, one of main bystander effects. |
2018-11-26 |
2023-08-13 |
Not clear |
| By Jihye Choi, Kyung Oh Jung, Edward E Graves, Guillem Prat. A gold nanoparticle system for the enhancement of radiotherapy and simultaneous monitoring of reactive-oxygen-species formation. Nanotechnology. vol 29. issue 50. 2018-11-26. PMID:30229748. |
these nps were able to effectively radiosensitize cells, as measured by increased cell apoptosis following rt. |
2018-11-26 |
2023-08-13 |
Not clear |
| Zhenyu Duan, Hao Cai, Hu Zhang, Kai Chen, Ning Li, Zhuping Xu, Qiyong Gong, Kui Lu. PEGylated Multistimuli-Responsive Dendritic Prodrug-Based Nanoscale System for Enhanced Anticancer Activity. ACS applied materials & interfaces. vol 10. issue 42. 2018-11-26. PMID:30246536. |
in vitro studies on dox released from the nps induced mitochondrial dysfunction during apoptosis. |
2018-11-26 |
2023-08-13 |
mouse |
| Zhenyu Duan, Hao Cai, Hu Zhang, Kai Chen, Ning Li, Zhuping Xu, Qiyong Gong, Kui Lu. PEGylated Multistimuli-Responsive Dendritic Prodrug-Based Nanoscale System for Enhanced Anticancer Activity. ACS applied materials & interfaces. vol 10. issue 42. 2018-11-26. PMID:30246536. |
in the 4t1 breast cancer model, these nps exhibited a superior antitumor efficacy confirmed by inhibiting angiogenesis, proliferation of tumor tissues, and inducing procedural apoptosis of tumor cells. |
2018-11-26 |
2023-08-13 |
mouse |