Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Mahadevaiah, Nawneet K Kurrey, G K Gowtham, R Somsheka. Laser-ablation-synthesized nanoparticles and animal cell lines studies. Journal of biosciences. vol 44. issue 6. 2020-05-27. PMID:31894116. |
nps exhibit cytotoxic effects in cancer cells by inducing apoptosis. |
2020-05-27 |
2023-08-13 |
Not clear |
Kuang-Chi Lai, Fu-Shin Chueh, Yung-Ting Hsiao, Zheng-Yu Cheng, Jin-Cherng Lien, Kuo-Ching Liu, Shu-Fen Peng, Jing-Gung Chun. Gefitinib and curcumin-loaded nanoparticles enhance cell apoptosis in human oral cancer SAS cells in vitro and inhibit SAS cell xenografted tumor in vivo. Toxicology and applied pharmacology. vol 382. 2020-05-20. PMID:31470033. |
however, there is no available information to show whether gef/cur nanoparticles (nps) increased cell apoptosis and anti-tumor effects on xenograft mice model in vivo. |
2020-05-20 |
2023-08-13 |
mouse |
Xi Li, Qi Wang, Guoying Deng, Yinping Liu, Boxuan Wei, Xijian Liu, Wei Bao, Qiugen Wang, Sufang W. Porous Se@SiO2 nanospheres attenuate cisplatin-induced acute kidney injury via activation of Sirt1. Toxicology and applied pharmacology. vol 380. 2020-05-19. PMID:31400413. |
in addition, therapy with nps attenuated apoptosis in cells and kidney tissues treated with cddp. |
2020-05-19 |
2023-08-13 |
human |
Behnaz Ghaemi, Arfa Moshiri, Inge K Herrmann, Mohammad Javad Hajipour, Peter Wick, Amir Amani, Sharmin Kharraz. Supramolecular Insights into Domino Effects of Ag@ZnO-Induced Oxidative Stress in Melanoma Cancer Cells. ACS applied materials & interfaces. vol 11. issue 50. 2020-05-06. PMID:31729218. |
taken together, ag@zno nps induce stress-related golgi fragmentation and autophagy, finally leading to melanoma cell apoptosis. |
2020-05-06 |
2023-08-13 |
Not clear |
Can Yang Zhang, Xinyue Dong, Jin Gao, Wenjing Lin, Ze Liu, Zhenjia Wan. Nanoparticle-induced neutrophil apoptosis increases survival in sepsis and alleviates neurological damage in stroke. Science advances. vol 5. issue 11. 2020-05-04. PMID:31723603. |
here, we report a method in which doxorubicin (dox)-conjugated protein nanoparticles (nps) can in situ selectively target inflammatory neutrophils for intracellular delivery of dox that induces neutrophil apoptosis. |
2020-05-04 |
2023-08-13 |
mouse |
N V Srikanth Vallabani, Souvik Sengupta, Ritesh Kumar Shukla, Ashutosh Kuma. ZnO nanoparticles-associated mitochondrial stress-induced apoptosis and G2/M arrest in HaCaT cells: a mechanistic approach. Mutagenesis. vol 34. issue 3. 2020-04-30. PMID:31271644. |
in together, our data revealed the mechanism of ros generation that triggers apoptosis and dna damage in hacat cell lines exposed to zno nps. |
2020-04-30 |
2023-08-13 |
Not clear |
Rong Ma, Zhigang Wang, Li Yan, Xianfeng Chen, Guangyu Zh. Novel Pt-loaded layered double hydroxide nanoparticles for efficient and cancer-cell specific delivery of a cisplatin prodrug. Journal of materials chemistry. B. vol 2. issue 30. 2020-04-08. PMID:32261778. |
we find that ldh is able to significantly improve both the cellular uptake of pt and genomic dna platination in cancer cells, and the pt-loaded nps induce severe apoptosis in cancer but not normal cells. |
2020-04-08 |
2023-08-13 |
Not clear |
Fangcheng Chen, Jun Wu, Chunli Zheng, Jiabi Zhu, Yajie Zhang, Xinru You, Fujuan Cai, Vishva Shah, Jianping Liu, Liang G. TPGS modified reduced bovine serum albumin nanoparticles as a lipophilic anticancer drug carrier for overcoming multidrug resistance. Journal of materials chemistry. B. vol 4. issue 22. 2020-04-08. PMID:32263095. |
in particular, enhanced cytotoxicity and ptx-induced apoptosis were observed in the drug-resistant mcf-7/adr cells compared to the taxol and ptx-loaded bsa nps. |
2020-04-08 |
2023-08-13 |
cattle |
Jing Li, Yue Gu, Wei Zhang, Cui-Yu Bao, Cai-Rong Li, Jing-Yi Zhang, Tao Liu, Shuai Li, Jia-Xi Huang, Zhi-Gang Xie, Shu-Cheng Hua, Ying Wa. Molecular Mechanism for Selective Cytotoxicity towards Cancer Cells of Diselenide-Containing Paclitaxel Nanoparticles. International journal of biological sciences. vol 15. issue 8. 2020-04-06. PMID:31360117. |
simultaneously, septx nps can successfully induce oxidative stress, cause mitochondrial dysfunction, resulting in mitochondrial pathway-mediated apoptosis, which is related to the upregulation of autophagy-related protein lc3-ii. |
2020-04-06 |
2023-08-13 |
mouse |
Xiaoyu Zhang, Manli Zhong, Pu Zhao, Xiancheng Zhang, You Li, Xuliang Wang, Jia Sun, Wang Lan, Hehong Sun, Zhanyou Wang, Huiling Ga. Screening a specific Zn(ii)-binding peptide for improving the cognitive decline of Alzheimer's disease in APP/PS1 transgenic mice by inhibiting Zn Biomaterials science. vol 7. issue 12. 2020-04-01. PMID:31588929. |
zn2+-induced neurotoxicity, oxidative stress, and apoptosis were attenuated by peg/pzn-cs nps. |
2020-04-01 |
2023-08-13 |
mouse |
Jie Gu, Zhen Ren, Jinfeng Zhao, Frank Addai Peprah, Yimin Xie, Dongrui Cheng, Yanwei Wang, Haitao Liu, Chris Kong Chu Wong, Yang Zhou, Haifeng Sh. Calcimimetic compound NPS R-467 protects against chronic cadmium-induced mouse kidney injury by restoring autophagy process. Ecotoxicology and environmental safety. vol 189. 2020-03-13. PMID:31830606. |
however, nps r-467 restored cd-inhibited autophagy flux and reduced cd-induced kidney apoptosis and injury. |
2020-03-13 |
2023-08-13 |
mouse |
Xinlong Zang, Xiaoxu Zhang, Haiyang Hu, Mingxi Qiao, Xiuli Zhao, Yihui Deng, Dawei Che. Targeted Delivery of Zoledronate to Tumor-Associated Macrophages for Cancer Immunotherapy. Molecular pharmaceutics. vol 16. issue 5. 2020-03-10. PMID:30969779. |
the nps specifically targeted tams and induced their apoptosis in vitro and in vivo. |
2020-03-10 |
2023-08-13 |
mouse |
Xin Zeng, Jie Sun, Suping Li, Jiyun Shi, Han Gao, Wei Sun Leong, Yiqi Wu, Minghui Li, Chengxin Liu, Ping Li, Jing Kong, Yi-Zhou Wu, Guangjun Nie, Yuming Fu, Gen Zhan. Blood-triggered generation of platinum nanoparticle functions as an anti-cancer agent. Nature communications. vol 11. issue 1. 2020-02-18. PMID:31992692. |
additionally, the pt nps are safe for use in humans and can act as anti-cancer agents to inhibit chemotherapy-resistant tumor growth by consuming intracellular glutathione and activating apoptosis. |
2020-02-18 |
2023-08-13 |
human |
Fanghong Luo, Zhongxiong Fan, Wen Yin, Liu Yang, Tingting Li, Lubin Zhong, Yang Li, Shengyu Wang, Jianghua Yan, Zhenqing Hou, Qiqing Zhan. pH-responsive stearic acid-O-carboxymethyl chitosan assemblies as carriers delivering small molecular drug for chemotherapy. Materials science & engineering. C, Materials for biological applications. vol 105. 2020-02-04. PMID:31546448. |
consequently, compared with cremophor el-based free ptx treatment, ptx-sa-cmc nps under ph-stimuli accomplished highly efficient apoptosis in cancer cells and effectively suppression of tumors by chemotherapy. |
2020-02-04 |
2023-08-13 |
Not clear |
Miao Hao, Chenfei Kong, Chengwei Jiang, Ruizhi Hou, Xiaoming Zhao, Jing Li, Yuqian Wang, Yiyao Gao, Hao Zhang, Bai Yang, Jinlan Jian. Polydopamine-coated Au-Ag nanoparticle-guided photothermal colorectal cancer therapy through multiple cell death pathways. Acta biomaterialia. vol 83. 2020-01-29. PMID:30366131. |
the results suggest that au-ag@pda nps significantly inhibited cell proliferation and induced apoptosis in colorectal cancer cells. |
2020-01-29 |
2023-08-13 |
mouse |
Miao Hao, Chenfei Kong, Chengwei Jiang, Ruizhi Hou, Xiaoming Zhao, Jing Li, Yuqian Wang, Yiyao Gao, Hao Zhang, Bai Yang, Jinlan Jian. Polydopamine-coated Au-Ag nanoparticle-guided photothermal colorectal cancer therapy through multiple cell death pathways. Acta biomaterialia. vol 83. 2020-01-29. PMID:30366131. |
the mechanisms through which au-ag@pda nps induced colorectal cancer cell death involved multiple pathways, including caspase-dependent and -independent apoptosis, mitochondrial damage, lysosomal membrane permeability, and autophagy. |
2020-01-29 |
2023-08-13 |
mouse |
Jingcao Shen, Dan Yang, Xingfan Zhou, Yuqian Wang, Shichuan Tang, Hong Yin, Jinglei Wang, Rui Chen, Jiaxiang Che. Role of Autophagy in Zinc Oxide Nanoparticles-Induced Apoptosis of Mouse LEYDIG Cells. International journal of molecular sciences. vol 20. issue 16. 2020-01-23. PMID:31430870. |
zinc oxide nanoparticles (zno nps) have shown adverse health impact on the human male reproductive system, with evidence of inducing apoptosis. |
2020-01-23 |
2023-08-13 |
mouse |
Jingcao Shen, Dan Yang, Xingfan Zhou, Yuqian Wang, Shichuan Tang, Hong Yin, Jinglei Wang, Rui Chen, Jiaxiang Che. Role of Autophagy in Zinc Oxide Nanoparticles-Induced Apoptosis of Mouse LEYDIG Cells. International journal of molecular sciences. vol 20. issue 16. 2020-01-23. PMID:31430870. |
however, whether or not zno nps could promote autophagy, and the possible role of autophagy in the progress of apoptosis, remain unclear. |
2020-01-23 |
2023-08-13 |
mouse |
Jingcao Shen, Dan Yang, Xingfan Zhou, Yuqian Wang, Shichuan Tang, Hong Yin, Jinglei Wang, Rui Chen, Jiaxiang Che. Role of Autophagy in Zinc Oxide Nanoparticles-Induced Apoptosis of Mouse LEYDIG Cells. International journal of molecular sciences. vol 20. issue 16. 2020-01-23. PMID:31430870. |
in vitro tests showed that zno nps could induce apoptosis and autophagy with the generation of oxidative stress. |
2020-01-23 |
2023-08-13 |
mouse |
Jingcao Shen, Dan Yang, Xingfan Zhou, Yuqian Wang, Shichuan Tang, Hong Yin, Jinglei Wang, Rui Chen, Jiaxiang Che. Role of Autophagy in Zinc Oxide Nanoparticles-Induced Apoptosis of Mouse LEYDIG Cells. International journal of molecular sciences. vol 20. issue 16. 2020-01-23. PMID:31430870. |
in summary, zno nps can induce apoptosis and autophagy via oxidative stress, and autophagy might play a protective role in zno nps-induced apoptosis of mouse leydig cells. |
2020-01-23 |
2023-08-13 |
mouse |