| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jingcao Shen, Dan Yang, Xingfan Zhou, Yuqian Wang, Shichuan Tang, Hong Yin, Jinglei Wang, Rui Chen, Jiaxiang Che. Role of Autophagy in Zinc Oxide Nanoparticles-Induced Apoptosis of Mouse LEYDIG Cells. International journal of molecular sciences. vol 20. issue 16. 2020-01-23. PMID:31430870. |
in vitro tests showed that zno nps could induce apoptosis and autophagy with the generation of oxidative stress. |
2020-01-23 |
2023-08-13 |
mouse |
| Jingcao Shen, Dan Yang, Xingfan Zhou, Yuqian Wang, Shichuan Tang, Hong Yin, Jinglei Wang, Rui Chen, Jiaxiang Che. Role of Autophagy in Zinc Oxide Nanoparticles-Induced Apoptosis of Mouse LEYDIG Cells. International journal of molecular sciences. vol 20. issue 16. 2020-01-23. PMID:31430870. |
in summary, zno nps can induce apoptosis and autophagy via oxidative stress, and autophagy might play a protective role in zno nps-induced apoptosis of mouse leydig cells. |
2020-01-23 |
2023-08-13 |
mouse |
| Xiang Ling, Jiasheng Tu, Junqing Wang, Aram Shajii, Na Kong, Chan Feng, Ye Zhang, Mikyung Yu, Tian Xie, Zameer Bharwani, Bader M Aljaeid, Bingyang Shi, Wei Tao, Omid C Farokhza. Glutathione-Responsive Prodrug Nanoparticles for Effective Drug Delivery and Cancer Therapy. ACS nano. vol 13. issue 1. 2020-01-21. PMID:30485068. |
upon reduction by cytoplasmic reductants, particularly gsh, p6 nps under disintegration released sufficient active pt(ii) metabolites, which covalently bound to target dna and induced significant apoptosis. |
2020-01-21 |
2023-08-13 |
Not clear |
| Paula Kielbik, Jaroslaw Kaszewski, Sebastian Dabrowski, Ricardo Faundez, Barlomiej S Witkowski, Lukasz Wachnicki, Yaroslav Zhydachevskyy, Rafal Sapierzynski, Zdzislaw Gajewski, Marek Godlewski, Michal M Godlewsk. Transfer of orally administered ZnO:Eu nanoparticles through the blood-testis barrier: the effect on kinetic sperm parameters and apoptosis in mice testes. Nanotechnology. vol 30. issue 45. 2020-01-21. PMID:31362276. |
the aim of our study was to determine the effect of fluorescent europium-doped zinc oxide nanoparticles (zno:eu nps) on sperm parameters, cell apoptosis and integrity of the blood-testis barrier (btb) in mice. |
2020-01-21 |
2023-08-13 |
mouse |
| Lu Kong, Wangcheng Hu, Xiaojie Gao, Yongya Wu, Yuying Xue, Keping Cheng, Meng Tan. Molecular mechanisms underlying nickel nanoparticle induced rat Sertoli-germ cells apoptosis. The Science of the total environment. vol 692. 2020-01-13. PMID:31349165. |
a series of investigations were performed to observe the role of ni nps on the apoptosis of sertoli-germ cells and to explore the long-chain non-coding rna (lncrna) functions on key signaling pathways and regulatory mechanisms. |
2020-01-13 |
2023-08-13 |
rat |
| Xueran Lin, Junhao Zhao, Wei Huang, Hongxing Liu, Pengju Feng, Fang Yang, Tianfeng Che. Simple Aggregation-Induced Emission-Based Multifunctional Fluorescent Dots for Cancer Therapy In Vitro. Chemistry, an Asian journal. vol 14. issue 23. 2020-01-13. PMID:31657112. |
moreover, the synthesized nanoparticles (nps) demonstrate potent cytotoxicity against human u87 glioblastoma cells by inducing cell apoptosis via triggering intracellular ros overproduction. |
2020-01-13 |
2023-08-13 |
human |
| Jingyi Zhang, Ying Wang, Cuiyu Bao, Tao Liu, Shuai Li, Jiaxi Huang, Ying Wan, Jing L. Curcumin‑loaded PEG‑PDLLA nanoparticles for attenuating palmitate‑induced oxidative stress and cardiomyocyte apoptosis through AMPK pathway. International journal of molecular medicine. vol 44. issue 2. 2019-12-23. PMID:31173176. |
it was found that cur nps were able to control the release of cur and to deliver cur to h9c2 cells, and they could prevent palmitate‑treated h9c2 cells from apoptosis. |
2019-12-23 |
2023-08-13 |
Not clear |
| Jingyi Zhang, Ying Wang, Cuiyu Bao, Tao Liu, Shuai Li, Jiaxi Huang, Ying Wan, Jing L. Curcumin‑loaded PEG‑PDLLA nanoparticles for attenuating palmitate‑induced oxidative stress and cardiomyocyte apoptosis through AMPK pathway. International journal of molecular medicine. vol 44. issue 2. 2019-12-23. PMID:31173176. |
results suggest that cur nps can attenuate palmitate‑induced oxidative stress in cardiomyocytes and protect cardiomyocytes from apoptosis through the ampk pathway. |
2019-12-23 |
2023-08-13 |
Not clear |
| Cátia A Sousa, Helena M V M Soares, Eduardo V Soare. Nickel Oxide Nanoparticles Trigger Caspase- and Mitochondria-Dependent Apoptosis in the Yeast Saccharomyces cerevisiae. Chemical research in toxicology. vol 32. issue 2. 2019-12-20. PMID:30656935. |
yeast cells exposed to nio nps exhibited typical hallmarks of regulated cell death (rcd) by apoptosis [loss of cell proliferation capacity (cell viability), exposure of phosphatidylserine at the outer cytoplasmic membrane leaflet, nuclear chromatin condensation, and dna damage] in a process that required de novo protein synthesis. |
2019-12-20 |
2023-08-13 |
Not clear |
| Cátia A Sousa, Helena M V M Soares, Eduardo V Soare. Nickel Oxide Nanoparticles Trigger Caspase- and Mitochondria-Dependent Apoptosis in the Yeast Saccharomyces cerevisiae. Chemical research in toxicology. vol 32. issue 2. 2019-12-20. PMID:30656935. |
cells deficient in the apoptosis-inducing factor ( aif1Δ) displayed higher tolerance to nio nps, which reinforces the involvement of mitochondria in rcd by apoptosis. |
2019-12-20 |
2023-08-13 |
Not clear |
| Cátia A Sousa, Helena M V M Soares, Eduardo V Soare. Nickel Oxide Nanoparticles Trigger Caspase- and Mitochondria-Dependent Apoptosis in the Yeast Saccharomyces cerevisiae. Chemical research in toxicology. vol 32. issue 2. 2019-12-20. PMID:30656935. |
in summary, this study shows that nio nps induce caspase- and mitochondria-dependent apoptosis in yeast. |
2019-12-20 |
2023-08-13 |
Not clear |
| Pakatip Ruenraroengsak, Darya Kiryushko, Ioannis G Theodorou, Michał M Klosowski, Erik R Taylor, Thisa Niriella, Carlo Palmieri, Ernesto Yagüe, Mary P Ryan, R Charles Coombes, Fang Xie, Alexandra E Porte. Frizzled-7-targeted delivery of zinc oxide nanoparticles to drug-resistant breast cancer cells. Nanoscale. vol 11. issue 27. 2019-12-18. PMID:31157349. |
zno nanoparticles (nps) have potential in cancer therapy due to their ability to potently and selectively induce cancer cell apoptosis. |
2019-12-18 |
2023-08-13 |
Not clear |
| Xuejing Zhang, Shiwei Niu, Gareth R Williams, Jianrong Wu, Xia Chen, Hong Zheng, Li-Min Zh. Dual-responsive nanoparticles based on chitosan for enhanced breast cancer therapy. Carbohydrate polymers. vol 221. 2019-12-03. PMID:31227170. |
histopathological studies revealed that the nps led to enhanced apoptosis in the tumor site, which resulted in reduced tumor growth. |
2019-12-03 |
2023-08-13 |
mouse |
| Amin Boroumand Moghaddam, Mona Moniri, Susan Azizi, Raha Abdul Rahim, Arbakariya Bin Ariff, Mohammad Navaderi, Rosfarizan Mohama. Eco-Friendly Formulated Zinc Oxide Nanoparticles: Induction of Cell Cycle Arrest and Apoptosis in the MCF-7 Cancer Cell Line. Genes. vol 8. issue 10. 2019-11-20. PMID:29053567. |
the present study aims to examine the cell cycle profile, status of cell death, and pathways of apoptosis in breast cancer cells (mcf-7) treated with biosynthesized zno nps. |
2019-11-20 |
2023-08-13 |
Not clear |
| Cong-Cong Hou, Jun-Quan Zh. Nanoparticles and female reproductive system: how do nanoparticles affect oogenesis and embryonic development. Oncotarget. vol 8. issue 65. 2019-11-20. PMID:29312650. |
when nps enter a pregnant woman's body through inhalation, venous injection, ingestion or skin permeation, maternal toxic stress reactions such as reactive oxygen species (ros), inflammation, apoptosis and endocrine dyscrasia are induced in different organs, particularly in the reproductive organs. |
2019-11-20 |
2023-08-13 |
Not clear |
| Cong-Cong Hou, Jun-Quan Zh. Nanoparticles and female reproductive system: how do nanoparticles affect oogenesis and embryonic development. Oncotarget. vol 8. issue 65. 2019-11-20. PMID:29312650. |
some nps can cross the placenta into the fetus by passive diffusion or endocytosis, which can trigger fetal inflammation, apoptosis, genotoxicity, cytotoxicity, low weight, reproductive deficiency, nervous damage, and immunodeficiency, among others. |
2019-11-20 |
2023-08-13 |
Not clear |
| Ali Masjedi, Hadi Hassannia, Fatemeh Atyabi, Ali Rastegari, Mohammad Hojjat-Farsangi, Afshin Namdar, Hassan Soleimanpour, Gholamreza Azizi, Afshin Nikkhoo, Ghasem Ghalamfarsa, Abbas Mirshafiey, Farhad Jadidi-Niarag. Downregulation of A2AR by siRNA loaded PEG-chitosan-lactate nanoparticles restores the T cell mediated anti-tumor responses through blockage of PKA/CREB signaling pathway. International journal of biological macromolecules. vol 133. 2019-11-14. PMID:30936011. |
t cells were treated with a2ar sirna-loaded nps demonstrated suppressed expression of a2ar which was associated with increased proliferation, reduced apoptosis, increased production of inflammatory and reduced secretion of inhibitory cytokines compared to untreated t cells. |
2019-11-14 |
2023-08-13 |
mouse |
| Guanping He, Yunlong Ma, Ye Zhu, Lei Yong, Xiao Liu, Peng Wang, Chen Liang, Chenlong Yang, Zhigang Zhao, Bao Hai, Xiaoyu Pan, Zhongjun Liu, Xiaoguang Liu, Chuanbin Ma. Cross Talk Between Autophagy and Apoptosis Contributes to ZnO Nanoparticle-Induced Human Osteosarcoma Cell Death. Advanced healthcare materials. vol 7. issue 17. 2019-11-08. PMID:29900694. |
here, it is found that the nps induce cross talk between apoptosis and autophagy, which leads to osteosarcoma cell death. |
2019-11-08 |
2023-08-13 |
human |
| Yibing Jiang, Xiwei Yu, Chang Su, Liang Zhao, Yijie Sh. Chitosan nanoparticles induced the antitumor effect in hepatocellular carcinoma cells by regulating ROS-mediated mitochondrial damage and endoplasmic reticulum stress. Artificial cells, nanomedicine, and biotechnology. vol 47. issue 1. 2019-10-17. PMID:30873872. |
in this study, we found that cs nps induced the massive generation of ros and resulted in apoptosis of hepatocellular carcinoma cells (smmc-7721) through activating the mitochondrial pathway and endoplasmic reticulum stress. |
2019-10-17 |
2023-08-13 |
Not clear |
| Yuquan Wang, Lanlan Li, Weibo Zhao, Yin Dou, Huijie An, Hui Tao, Xiaoqiu Xu, Yi Jia, Shan Lu, Jianxiang Zhang, Houyuan H. Targeted Therapy of Atherosclerosis by a Broad-Spectrum Reactive Oxygen Species Scavenging Nanoparticle with Intrinsic Anti-inflammatory Activity. ACS nano. vol 12. issue 9. 2019-10-07. PMID:30114351. |
tpcd nps significantly attenuated ros-induced inflammation and cell apoptosis in macrophages, by eliminating overproduced intracellular ros. |
2019-10-07 |
2023-08-13 |
Not clear |