| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Meeta Gera, Nameun Kim, Mrinmoy Ghosh, Neelesh Sharma, Do Luong Huynh, Nisansala Chandimali, Hyebin Koh, Jiao Jiao Zhang, Tae Yoon Kang, Yang Ho Park, Taeho Kwon, Dong Kee Jeon. Synthesis and evaluation of the antiproliferative efficacy of BRM270 phytocomposite nanoparticles against human hepatoma cancer cell lines. Materials science & engineering. C, Materials for biological applications. vol 97. 2019-06-17. PMID:30678901. |
taken together, our findings demonstrated that these uniquely engineered brm270 nps effectively enter into the cancer cells due to its acidic microenvironment thereby inducing apoptosis and regulate the cell-proliferation in-vitro at extremely low dosages. |
2019-06-17 |
2023-08-13 |
human |
| Wenjing Wang, Jie Liu, Wenjie Feng, Shulin Du, Rui Ge, Jing Li, Yi Liu, Hongchen Sun, Daqi Zhang, Hao Zhang, Bai Yan. Targeting mitochondria with Au-Ag@Polydopamine nanoparticles for papillary thyroid cancer therapy. Biomaterials science. vol 7. issue 3. 2019-06-14. PMID:30628592. |
in addition, despite cancer cells being able to survive by an autophagy-mediated pathway to escape apoptosis or necrosis, targeting mitochondria by au-ag@pda nps enables the destructive thermal ablation of tpc-1 cells by combination with photothermal therapy. |
2019-06-14 |
2023-08-13 |
human |
| Meimei Wang, Juan Wang, Yun Liu, Jingjing Wang, Yaguang Nie, Bo Si, Ying Liu, Xue Wang, Shaopeng Chen, Tom K Hei, Lijun Wu, Guoping Zhao, An X. Subcellular targets of zinc oxide nanoparticles during the aging process: role of cross-talk between mitochondrial dysfunction and endoplasmic reticulum stress in the genotoxic response. Toxicological sciences : an official journal of the Society of Toxicology. 2019-06-07. PMID:31173148. |
the present study found that the acute cytotoxic effects of fresh zno nps was largely regulated by mitochondria-dependent apoptosis, which the level of cleaved caspase-3 and mitochondria damage were significantly higher than that of 60 day-aged zno nps. |
2019-06-07 |
2023-08-13 |
cat |
| Akash Sharma, Brian Gorey, Alan Case. In vitro comparative cytotoxicity study of aminated polystyrene, zinc oxide and silver nanoparticles on a cervical cancer cell line. Drug and chemical toxicology. vol 42. issue 1. 2019-06-03. PMID:29359584. |
these findings suggest that all three nps resulted in the decrease in cell viability, increase intracellular ros production, induce cell cycle arrest at the g2/m phase and finally result in cell death by caspase-mediated apoptosis, which is irrespective of their differences in physiochemical properties and attached surface groups. |
2019-06-03 |
2023-08-13 |
Not clear |
| J Taylor, J Milton, M Willett, J Wingfield, S Mahaja. What do we actually see in intracellular SERS? Investigating nanosensor-induced variation. Faraday discussions. vol 205. 2019-05-31. PMID:28901362. |
while aunps are generally considered non-toxic to cells, many biological and toxicity studies report that exposure to nps induces cell stress through the generation of reactive oxygen species (ros) and the upregulated transcription of pro-inflammatory genes, which can result in severe genotoxicity and apoptosis. |
2019-05-31 |
2023-08-13 |
Not clear |
| Carolina Sánchez-Rodríguez, Raquel Palao-Suay, Laura Rodrigáñez, María Rosa Aguilar, Sergio Martín-Saldaña, Julio San Román, Ricardo Sanz-Fernánde. α-Tocopheryl Succinate-Based Polymeric Nanoparticles for the Treatment of Head and Neck Squamous Cell Carcinoma. Biomolecules. vol 8. issue 3. 2019-05-29. PMID:30235821. |
we analyzed the effect of the newly synthetized α-tos-loaded nps in proliferating endothelial cells and hypopharynx carcinoma squamous cells and measured markers of angiogenesis, apoptosis and reactive oxygen species (ros). |
2019-05-29 |
2023-08-13 |
Not clear |
| Carolina Sánchez-Rodríguez, Raquel Palao-Suay, Laura Rodrigáñez, María Rosa Aguilar, Sergio Martín-Saldaña, Julio San Román, Ricardo Sanz-Fernánde. α-Tocopheryl Succinate-Based Polymeric Nanoparticles for the Treatment of Head and Neck Squamous Cell Carcinoma. Biomolecules. vol 8. issue 3. 2019-05-29. PMID:30235821. |
α-tos-loaded nps suppressed angiogenesis by inducing accumulation of ros and inducing apoptosis of proliferating endothelial cells. |
2019-05-29 |
2023-08-13 |
Not clear |
| Sara Haji Hosseinali, Zahra Pourmokhtar Boushehri, Behnam Rasti, Mirsasan Mirpour, Koorosh Shahpasand, Mojtaba Falahat. Biophysical, molecular dynamics and cellular studies on the interaction of nickel oxide nanoparticles with tau proteins and neuron-like cells. International journal of biological macromolecules. vol 125. 2019-05-16. PMID:30528999. |
cytotoxic activity of nio nps against sh-sy5y cell was determined by trypan blue exclusion, cell morphology, ros, and apoptosis assays. |
2019-05-16 |
2023-08-13 |
Not clear |
| Sara Haji Hosseinali, Zahra Pourmokhtar Boushehri, Behnam Rasti, Mirsasan Mirpour, Koorosh Shahpasand, Mojtaba Falahat. Biophysical, molecular dynamics and cellular studies on the interaction of nickel oxide nanoparticles with tau proteins and neuron-like cells. International journal of biological macromolecules. vol 125. 2019-05-16. PMID:30528999. |
nio nps also provided a significant impact on generating intracellular ros and apoptosis induction. |
2019-05-16 |
2023-08-13 |
Not clear |
| Somayeh Handali, Eskandar Moghimipour, Mohsen Rezaei, Sadegh Saremy, Farid Abedin Dorkoos. Co-delivery of 5-fluorouracil and oxaliplatin in novel poly(3-hydroxybutyrate-co-3-hydroxyvalerate acid)/poly(lactic-co-glycolic acid) nanoparticles for colon cancer therapy. International journal of biological macromolecules. vol 124. 2019-04-25. PMID:30248424. |
in the present study, a novel 5fu and oxa co-loaded phbv/plga nps was developed which induced apoptosis in cancer cells. |
2019-04-25 |
2023-08-13 |
Not clear |
| Jing Xia, Liuwei Zhang, Ming Qian, Yongming Bao, Jingyun Wang, Yachen L. Specific light-up pullulan-based nanoparticles with reduction-triggered emission and activatable photoactivity for the imaging and photodynamic killing of cancer cells. Journal of colloid and interface science. vol 498. 2019-04-18. PMID:28324723. |
in mcf-7 cells, compared to non-reducible p-ppix nps with stable amide linkages, p-s-s-ppix nps displayed higher cytotoxicity and induced higher apoptosis rate of tumor cells with light irradiation treatment. |
2019-04-18 |
2023-08-13 |
Not clear |
| Yonghong Wang, Baofang Wen, Hongli Yu, Dejun Ding, JingJing Zhang, Yunxiang Zhang, Limin Zhao, Weifen Zhan. Berberine Hydrochloride-Loaded Chitosan Nanoparticles Effectively Targets and Suppresses Human Nasopharyngeal Carcinoma. Journal of biomedical nanotechnology. vol 14. issue 8. 2019-04-16. PMID:29903063. |
in this study, folate acid modified chitosan nanoparticles loaded berberine hydrochloride (bh/fa-cts nps) were prepared by the ionic cross-linking technique, the physicochemical properties and the influence of bh/fa-cts nps on proliferation, migration and apoptosis in human nasopharyngeal carcinoma cne-1 cells were studied in vitro and in vivo. |
2019-04-16 |
2023-08-13 |
human |
| Yonghong Wang, Baofang Wen, Hongli Yu, Dejun Ding, JingJing Zhang, Yunxiang Zhang, Limin Zhao, Weifen Zhan. Berberine Hydrochloride-Loaded Chitosan Nanoparticles Effectively Targets and Suppresses Human Nasopharyngeal Carcinoma. Journal of biomedical nanotechnology. vol 14. issue 8. 2019-04-16. PMID:29903063. |
bh/fa-cts nps promoted apoptosis and necrosis of cne-1 cells. |
2019-04-16 |
2023-08-13 |
human |
| Vivek K Pawar, Yuvraj Singh, Komal Sharma, Arpita Shrivastav, Abhisheak Sharma, Akhilesh Singh, Jaya Gopal Meher, Pankaj Singh, Kavit Raval, Animesh Kumar, Himangshu K Bora, Dipak Datta, Jawahar Lal, Manish K Chourasi. Improved chemotherapy against breast cancer through immunotherapeutic activity of fucoidan decorated electrostatically assembled nanoparticles bearing doxorubicin. International journal of biological macromolecules. vol 122. 2019-04-08. PMID:30219515. |
fcd nps offered improved cytotoxicity (2.64 folds), cell cycle arrest in g1-s phase (34.65%) and apoptosis (66.12%) in tumor cells compared to free dox. |
2019-04-08 |
2023-08-13 |
mouse |
| Tao Wang, Xin Wen, Yadong Hu, Xinyu Zhang, Dan Wang, Shaowu Yi. Copper nanoparticles induced oxidation stress, cell apoptosis and immune response in the liver of juvenile Takifugu fasciatus. Fish & shellfish immunology. vol 84. 2019-03-22. PMID:30366095. |
we investigated the effects of cu nps exposure on oxidative stress, apoptosis and immune response in an economically important model species, takifugu fasciatus. |
2019-03-22 |
2023-08-13 |
cat |
| Tao Wang, Xin Wen, Yadong Hu, Xinyu Zhang, Dan Wang, Shaowu Yi. Copper nanoparticles induced oxidation stress, cell apoptosis and immune response in the liver of juvenile Takifugu fasciatus. Fish & shellfish immunology. vol 84. 2019-03-22. PMID:30366095. |
oxidative stress indicators [malondialdehyde (mda), total superoxide dismutase (t-sod), catalase (cat) and glutathione (gsh)], apoptosis index and activities of caspases (caspase-3, caspase-9) were all increased with the increase of cu nps concentration in liver. |
2019-03-22 |
2023-08-13 |
cat |
| Yuki Takabayashi, Masahiro Kuwabara, Yoko Sato, Masayuki Ishihara, Megumi Takikawa, Shingo Nakamura, Koichi Fukuda, Sumiyo Hiruma, Tomoharu Kiyosaw. FGF-2-containing dalteparin/protamine nanoparticles (FGF-2&D/P NPs) ameliorate UV-induced skin photoaging in hairless mice. Journal of plastic surgery and hand surgery. vol 52. issue 6. 2019-03-20. PMID:30442053. |
thus, fgf-2&d/p nps may be effective in preventing skin photoaging accelerated by uvb irradiation such as declining elasticity, acanthosis, and apoptosis of dfcs and ekcs. |
2019-03-20 |
2023-08-13 |
mouse |
| Pengyu Chen, Han Wang, Man He, Beibei Chen, Bin Yang, Bin H. Size-dependent cytotoxicity study of ZnO nanoparticles in HepG2 cells. Ecotoxicology and environmental safety. vol 171. 2019-03-18. PMID:30616150. |
the internalization, cytotoxic mechanism, death mechanism and elimination behavior of three sizes of zno nps were studied by electrothermal vaporization (etv)-inductively coupled plasma mass spectrometry (icp-ms), mtt assays, gsh measurements, ros measurements and analyses of apoptosis and gene expression. |
2019-03-18 |
2023-08-13 |
Not clear |
| Behnaz Ghaemi, Elnaz Shaabani, Roqya Najafi-Taher, Saeedeh Jafari Nodooshan, Amin Sadeghpour, Sharmin Kharrazi, Amir Aman. Intracellular ROS Induction by Ag@ZnO Core-Shell Nanoparticles: Frontiers of Permanent Optically Active Holes in Breast Cancer Theranostic. ACS applied materials & interfaces. vol 10. issue 29. 2019-02-20. PMID:29932633. |
in this context, upregulation of apoptotic cascade proteins (i.e., bax/bcl2 association, p53, cytochrome c, and caspase-3) along with activation of oxidative stress proteins suggested the occurrence of apoptosis by ag@zno nps in cancer cells through the mitochondrial pathway. |
2019-02-20 |
2023-08-13 |
human |
| Benyu Su, Qiangdong Guan, Sufang Y. The neurotoxicity of nanoparticles: A bibliometric analysis. Toxicology and industrial health. vol 34. issue 12. 2019-02-13. PMID:30317940. |
the main research hot spots might focus on the pathogenesis of nps, such as oxidative stress and apoptosis. |
2019-02-13 |
2023-08-13 |
mouse |