| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Qiong Wang, Chenming Zou, Lingying Wang, Xueqin Gao, Jindan Wu, Songwei Tan, Gang W. Doxorubicin and adjudin co-loaded pH-sensitive nanoparticles for the treatment of drug-resistant cancer. Acta biomaterialia. vol 94. 2020-07-21. PMID:31141733. |
western blot and polymerase chain reaction analyses showed that inhibition of p-glycoprotein and x-linked inhibitor of apoptosis protein expression may underlie inhibition of tumor resistance mediated by nps. |
2020-07-21 |
2023-08-13 |
Not clear |
| Qiong Wang, Chenming Zou, Lingying Wang, Xueqin Gao, Jindan Wu, Songwei Tan, Gang W. Doxorubicin and adjudin co-loaded pH-sensitive nanoparticles for the treatment of drug-resistant cancer. Acta biomaterialia. vol 94. 2020-07-21. PMID:31141733. |
the mcf-7/adr xenograft tumor model also revealed that in comparison with dox, the nps exhibited satisfactory performance in promoting apoptosis of tumor cells and achieved high therapeutic outcomes for mdr tumors. |
2020-07-21 |
2023-08-13 |
Not clear |
| Yongya Wu, Jun Ma, Yufei Sun, Meng Tang, Lu Kon. Effect and mechanism of PI3K/AKT/mTOR signaling pathway in the apoptosis of GC-1 cells induced by nickel nanoparticles. Chemosphere. vol 255. 2020-07-02. PMID:32402875. |
the purpose of this study was to investigate the toxicity of ni nps on gc-1 cells, a mouse spermatogonia cell line, and to explore the possible mechanism underlying the induction of apoptosis via pi3k/akt/mtor signaling pathway. |
2020-07-02 |
2023-08-13 |
mouse |
| Yongya Wu, Jun Ma, Yufei Sun, Meng Tang, Lu Kon. Effect and mechanism of PI3K/AKT/mTOR signaling pathway in the apoptosis of GC-1 cells induced by nickel nanoparticles. Chemosphere. vol 255. 2020-07-02. PMID:32402875. |
the results showed that ni nps could not only cause changes in cell ultrastructure, decreased survival rate and arrested g1 phase cell cycle, but also activated apoptosis pathway by inhibiting the pi3k/akt/mtor signaling pathway. |
2020-07-02 |
2023-08-13 |
mouse |
| Naser Javan, Mohammad Hassan Khadem Ansari, Mehdi Dadashpour, Mehran Khojastehfard, Milad Bastami, Mohammad Rahmati-Yamchi, Nosratollah Zargham. Synergistic Antiproliferative Effects of Co-nanoencapsulated Curcumin and Chrysin on MDA-MB-231 Breast Cancer Cells Through Upregulating miR-132 and miR-502c. Nutrition and cancer. vol 71. issue 7. 2020-06-05. PMID:30955355. |
in addition, highest percentage of cell apoptosis was acquired in cells treated with curchr-loaded nps according to apoptosis analysis. |
2020-06-05 |
2023-08-13 |
Not clear |
| Fahimeh Hadi, Shima Tavakkol, Sophie Laurent, Vahid Pirhajati, Seied Rabi Mahdavi, Ali Neshastehriz, Ali Shakeri-Zade. Combinatorial effects of radiofrequency hyperthermia and radiotherapy in the presence of magneto-plasmonic nanoparticles on MCF-7 breast cancer cells. Journal of cellular physiology. vol 234. issue 11. 2020-06-02. PMID:30982979. |
the results obtained from mtt assay and qrt-pcr studies showed that nps and rf hyperthermia had no significant effect when applied separately, while their combination had synergistic effects on cell viability percentage and the level of apoptosis induction. |
2020-06-02 |
2023-08-13 |
human |
| Nidhi Chaubey, Amaresh Kumar Sahoo, Arun Chattopadhyay, Siddhartha Sankar Ghos. Silver nanoparticle loaded PLGA composite nanoparticles for improving therapeutic efficacy of recombinant IFNγ by targeting the cell surface. Biomaterials science. vol 2. issue 8. 2020-06-02. PMID:32482003. |
the interaction between the recombinant ifnγ with its cell surface receptors facilitated the delivery of the composite nps, and thus the combination of the duos ultimately led to induction of apoptosis in the cancer cells. |
2020-06-02 |
2023-08-13 |
human |
| Maqusood Ahamed, Mohd Javed Akhtar, Hisham A Alhadla. Influence of silica nanoparticles on cadmium-induced cytotoxicity, oxidative stress, and apoptosis in human liver HepG2 cells. Environmental toxicology. vol 35. issue 5. 2020-06-01. PMID:31904905. |
coexposure of si nps and cd also augmented mitochondria-mediated apoptosis in hepg2 cells indicated by altered regulation of apoptotic genes (p53, bax, bcl-2, caspase-3, and caspase-9) along with reduced mitochondrial membrane potential. |
2020-06-01 |
2023-08-13 |
human |
| Mahadevaiah, Nawneet K Kurrey, G K Gowtham, R Somsheka. Laser-ablation-synthesized nanoparticles and animal cell lines studies. Journal of biosciences. vol 44. issue 6. 2020-05-27. PMID:31894116. |
nps exhibit cytotoxic effects in cancer cells by inducing apoptosis. |
2020-05-27 |
2023-08-13 |
Not clear |
| Kuang-Chi Lai, Fu-Shin Chueh, Yung-Ting Hsiao, Zheng-Yu Cheng, Jin-Cherng Lien, Kuo-Ching Liu, Shu-Fen Peng, Jing-Gung Chun. Gefitinib and curcumin-loaded nanoparticles enhance cell apoptosis in human oral cancer SAS cells in vitro and inhibit SAS cell xenografted tumor in vivo. Toxicology and applied pharmacology. vol 382. 2020-05-20. PMID:31470033. |
however, there is no available information to show whether gef/cur nanoparticles (nps) increased cell apoptosis and anti-tumor effects on xenograft mice model in vivo. |
2020-05-20 |
2023-08-13 |
mouse |
| Xi Li, Qi Wang, Guoying Deng, Yinping Liu, Boxuan Wei, Xijian Liu, Wei Bao, Qiugen Wang, Sufang W. Porous Se@SiO2 nanospheres attenuate cisplatin-induced acute kidney injury via activation of Sirt1. Toxicology and applied pharmacology. vol 380. 2020-05-19. PMID:31400413. |
in addition, therapy with nps attenuated apoptosis in cells and kidney tissues treated with cddp. |
2020-05-19 |
2023-08-13 |
human |
| Behnaz Ghaemi, Arfa Moshiri, Inge K Herrmann, Mohammad Javad Hajipour, Peter Wick, Amir Amani, Sharmin Kharraz. Supramolecular Insights into Domino Effects of Ag@ZnO-Induced Oxidative Stress in Melanoma Cancer Cells. ACS applied materials & interfaces. vol 11. issue 50. 2020-05-06. PMID:31729218. |
taken together, ag@zno nps induce stress-related golgi fragmentation and autophagy, finally leading to melanoma cell apoptosis. |
2020-05-06 |
2023-08-13 |
Not clear |
| Can Yang Zhang, Xinyue Dong, Jin Gao, Wenjing Lin, Ze Liu, Zhenjia Wan. Nanoparticle-induced neutrophil apoptosis increases survival in sepsis and alleviates neurological damage in stroke. Science advances. vol 5. issue 11. 2020-05-04. PMID:31723603. |
here, we report a method in which doxorubicin (dox)-conjugated protein nanoparticles (nps) can in situ selectively target inflammatory neutrophils for intracellular delivery of dox that induces neutrophil apoptosis. |
2020-05-04 |
2023-08-13 |
mouse |
| N V Srikanth Vallabani, Souvik Sengupta, Ritesh Kumar Shukla, Ashutosh Kuma. ZnO nanoparticles-associated mitochondrial stress-induced apoptosis and G2/M arrest in HaCaT cells: a mechanistic approach. Mutagenesis. vol 34. issue 3. 2020-04-30. PMID:31271644. |
in together, our data revealed the mechanism of ros generation that triggers apoptosis and dna damage in hacat cell lines exposed to zno nps. |
2020-04-30 |
2023-08-13 |
Not clear |
| Rong Ma, Zhigang Wang, Li Yan, Xianfeng Chen, Guangyu Zh. Novel Pt-loaded layered double hydroxide nanoparticles for efficient and cancer-cell specific delivery of a cisplatin prodrug. Journal of materials chemistry. B. vol 2. issue 30. 2020-04-08. PMID:32261778. |
we find that ldh is able to significantly improve both the cellular uptake of pt and genomic dna platination in cancer cells, and the pt-loaded nps induce severe apoptosis in cancer but not normal cells. |
2020-04-08 |
2023-08-13 |
Not clear |
| Fangcheng Chen, Jun Wu, Chunli Zheng, Jiabi Zhu, Yajie Zhang, Xinru You, Fujuan Cai, Vishva Shah, Jianping Liu, Liang G. TPGS modified reduced bovine serum albumin nanoparticles as a lipophilic anticancer drug carrier for overcoming multidrug resistance. Journal of materials chemistry. B. vol 4. issue 22. 2020-04-08. PMID:32263095. |
in particular, enhanced cytotoxicity and ptx-induced apoptosis were observed in the drug-resistant mcf-7/adr cells compared to the taxol and ptx-loaded bsa nps. |
2020-04-08 |
2023-08-13 |
cattle |
| Jing Li, Yue Gu, Wei Zhang, Cui-Yu Bao, Cai-Rong Li, Jing-Yi Zhang, Tao Liu, Shuai Li, Jia-Xi Huang, Zhi-Gang Xie, Shu-Cheng Hua, Ying Wa. Molecular Mechanism for Selective Cytotoxicity towards Cancer Cells of Diselenide-Containing Paclitaxel Nanoparticles. International journal of biological sciences. vol 15. issue 8. 2020-04-06. PMID:31360117. |
simultaneously, septx nps can successfully induce oxidative stress, cause mitochondrial dysfunction, resulting in mitochondrial pathway-mediated apoptosis, which is related to the upregulation of autophagy-related protein lc3-ii. |
2020-04-06 |
2023-08-13 |
mouse |
| Xiaoyu Zhang, Manli Zhong, Pu Zhao, Xiancheng Zhang, You Li, Xuliang Wang, Jia Sun, Wang Lan, Hehong Sun, Zhanyou Wang, Huiling Ga. Screening a specific Zn(ii)-binding peptide for improving the cognitive decline of Alzheimer's disease in APP/PS1 transgenic mice by inhibiting Zn Biomaterials science. vol 7. issue 12. 2020-04-01. PMID:31588929. |
zn2+-induced neurotoxicity, oxidative stress, and apoptosis were attenuated by peg/pzn-cs nps. |
2020-04-01 |
2023-08-13 |
mouse |
| Jie Gu, Zhen Ren, Jinfeng Zhao, Frank Addai Peprah, Yimin Xie, Dongrui Cheng, Yanwei Wang, Haitao Liu, Chris Kong Chu Wong, Yang Zhou, Haifeng Sh. Calcimimetic compound NPS R-467 protects against chronic cadmium-induced mouse kidney injury by restoring autophagy process. Ecotoxicology and environmental safety. vol 189. 2020-03-13. PMID:31830606. |
however, nps r-467 restored cd-inhibited autophagy flux and reduced cd-induced kidney apoptosis and injury. |
2020-03-13 |
2023-08-13 |
mouse |
| Xinlong Zang, Xiaoxu Zhang, Haiyang Hu, Mingxi Qiao, Xiuli Zhao, Yihui Deng, Dawei Che. Targeted Delivery of Zoledronate to Tumor-Associated Macrophages for Cancer Immunotherapy. Molecular pharmaceutics. vol 16. issue 5. 2020-03-10. PMID:30969779. |
the nps specifically targeted tams and induced their apoptosis in vitro and in vivo. |
2020-03-10 |
2023-08-13 |
mouse |