| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Marion Vanharen, Denis Girar. Activation of Human Eosinophils with Nanoparticles: a New Area of Research. Inflammation. vol 43. issue 1. 2020-11-16. PMID:31376094. |
indeed, activation of eosinophils with nps could lead to modulation of spontaneous apoptosis, caspase activation, and cytoskeleton breakdown when apoptosis is induced; cytokine production, de novo protein synthesis, cellular adhesion onto a cell substratum, and cell signalling events such as activation of the phosphoinositide 3-kinase/akt pathway and actin re-localization are involved in np-induced adhesion. |
2020-11-16 |
2023-08-13 |
human |
| Somayeh Vandghanooni, Morteza Eskandani, Jaleh Barar, Yadollah Omid. Antisense LNA-loaded nanoparticles of star-shaped glucose-core PCL-PEG copolymer for enhanced inhibition of oncomiR-214 and nucleolin-mediated therapy of cisplatin-resistant ovarian cancer cells. International journal of pharmaceutics. vol 573. 2020-10-23. PMID:31705975. |
the oncomir-214 in a2780 r cells were harnessed by ap-lna-pcl nps, and nucleolin-mediated endocytosis of targeted polymeric ddss containing cis into mir-214-inhibited a2780 r cells caused enhanced apoptosis, which was further confirmed by apoptosis detection and evaluation of downstream genes expression. |
2020-10-23 |
2023-08-13 |
Not clear |
| Owais Mohammad, Syed Mohd Faisal, Nadeem Ahmad, Mohd Ahmar Rauf, Mohd Saad Umar, Anzar Abdul Mujeeb, Piyush Pachauri, Anees Ahmed, Mohammad Kashif, Mohammad Ajmal, Swaleha Zubai. Bio-mediated synthesis of 5-FU based nanoparticles employing orange fruit juice: a novel drug delivery system to treat skin fibrosarcoma in model animals. Scientific reports. vol 9. issue 1. 2020-10-21. PMID:31444363. |
the as-synthesized 5-fu nanoparticles (nps) retained the anti-neoplastic efficacy of the parent compound and induced apoptosis in cancer cells. |
2020-10-21 |
2023-08-13 |
mouse |
| Peng Gao, Mengzhen Wang, Yuanyuan Chen, Wei Pan, Ping Zhou, Xiuyan Wan, Na Li, Bo Tan. A COF-based nanoplatform for highly efficient cancer diagnosis, photodynamic therapy and prognosis. Chemical science. vol 11. issue 26. 2020-10-10. PMID:33033601. |
under nir laser irradiation, cof nps generated abundant reactive oxygen species (ros) to induce cancer cell apoptosis owing to their crystalline reticular structure. |
2020-10-10 |
2023-08-13 |
Not clear |
| Lipika Ray, Manish Kumar Pal, Ratan Singh Ra. Synergism of co-delivered nanosized antioxidants displayed enhanced anticancer efficacy in human colon cancer cell lines. Bioactive materials. vol 2. issue 2. 2020-10-01. PMID:29744415. |
triplex chemopreventive and/or therapeutic agents-loaded nps were synergistically inducing apoptosis in hct-116 cells compared to two-chemopreventive agents-loaded nps as evident by an increase in sub-g |
2020-10-01 |
2023-08-13 |
human |
| Valeria De Matteis, Mariafrancesca Cascione, Chiara Cristina Toma, Stefano Leporatt. Silver Nanoparticles: Synthetic Routes, In Vitro Toxicity and Theranostic Applications for Cancer Disease. Nanomaterials (Basel, Switzerland). vol 8. issue 5. 2020-10-01. PMID:29748469. |
in particular, we analyzed the physiological cellular pathway perturbations in terms of oxidative stress induction, mitochondrial membrane potential alteration, cell death, apoptosis, dna damage and cytokines secretion after ag nps exposure. |
2020-10-01 |
2023-08-13 |
Not clear |
| Iwona Inkielewicz-Stepniak, Lidia Tajber, Gavin Behan, Hongzhou Zhang, Marek W Radomski, Carlos Medina, Maria J Santos-Martine. The Role of Mucin in the Toxicological Impact of Polystyrene Nanoparticles. Materials (Basel, Switzerland). vol 11. issue 5. 2020-10-01. PMID:29751544. |
positive nps affected cell viability and induced apoptosis in all cell lines independently of their ability of produce mucin. |
2020-10-01 |
2023-08-13 |
Not clear |
| Jinhuan Jiang, Jiang Pi, Jiye Ca. The Advancing of Zinc Oxide Nanoparticles for Biomedical Applications. Bioinorganic chemistry and applications. vol 2018. 2020-10-01. PMID:30073019. |
zno nps have emerged a promising potential in biomedicine, especially in the fields of anticancer and antibacterial fields, which are involved with their potent ability to trigger excess reactive oxygen species (ros) production, release zinc ions, and induce cell apoptosis. |
2020-10-01 |
2023-08-13 |
Not clear |
| Yunlu Cai, Tiantian Gao, Shiping Fu, Ping Su. Development of zoledronic acid functionalized hydroxyapatite loaded polymeric nanoparticles for the treatment of osteoporosis. Experimental and therapeutic medicine. vol 16. issue 2. 2020-09-30. PMID:30116324. |
furthermore, hzl nps increased the cytotoxicity of hfob 1.19 cells and increased the proportion of cells in the early (18.1±12.4%), late (28.7±3.7%) and necrotic (67.5±1.2%) phases of apoptosis. |
2020-09-30 |
2023-08-13 |
Not clear |
| Jie Tang, Bei Li, Christopher B Howard, Stephen M Mahler, Kristofer J Thurecht, Yilun Wu, Leaf Huang, Zhi Ping X. Multifunctional lipid-coated calcium phosphate nanoplatforms for complete inhibition of large triple negative breast cancer via targeted combined therapy. Biomaterials. vol 216. 2020-09-30. PMID:31195300. |
such lcp-bsab nps loaded with cell death (cd)-sirna and indocyanine green (icg) were efficiently taken up by mda-mb-468 cells, significantly inducing cell apoptosis and synergistically suppressing cell proliferation upon irradiation of 808 nm near-infrared laser. |
2020-09-30 |
2023-08-13 |
Not clear |
| Shengliang Li, Qingyuan Deng, Xiao Li, Yongwei Huang, Xiaozhen Li, Fang Liu, Huijuan Wang, Weixia Qing, Zhonghua Liu, Chun-Sing Le. Bis-diketopyrrolopyrrole conjugated polymer nanoparticles as photothermic nanoagonist for specific and synergistic glioblastoma therapy. Biomaterials. vol 216. 2020-09-30. PMID:31212086. |
in particular, precise glioblastoma-specific capability and killing ability for glioblastoma cells were effectively achieved in vitro by treating with only pbdpp nps to induce cell apoptosis or by interaction with pbdpp nps under nir laser irradiation to trigger cell necrosis. |
2020-09-30 |
2023-08-13 |
Not clear |
| Daniel Hauser, Manuela Estermann, Ana Milosevic, Lukas Steinmetz, Dimitri Vanhecke, Dedy Septiadi, Barbara Drasler, Alke Petri-Fink, Vincent Ball, Barbara Rothen-Rutishause. Polydopamine/Transferrin Hybrid Nanoparticles for Targeted Cell-Killing. Nanomaterials (Basel, Switzerland). vol 8. issue 12. 2020-09-29. PMID:30562983. |
when irradiated, the melanoma cells exposed to pda/tf nps underwent apoptosis, faster than the control cells, pointing towards the ability of pda/tf to mediate uv-light-induced cell death. |
2020-09-29 |
2023-08-13 |
mouse |
| Daniel Hauser, Manuela Estermann, Ana Milosevic, Lukas Steinmetz, Dimitri Vanhecke, Dedy Septiadi, Barbara Drasler, Alke Petri-Fink, Vincent Ball, Barbara Rothen-Rutishause. Polydopamine/Transferrin Hybrid Nanoparticles for Targeted Cell-Killing. Nanomaterials (Basel, Switzerland). vol 8. issue 12. 2020-09-29. PMID:30562983. |
therefore, the herein presented polydopamine/protein nps constitute a versatile and stable system for cancer cell-targeting and photothermal apoptosis induction. |
2020-09-29 |
2023-08-13 |
mouse |
| Dong-Yung Kim, Jun-Hyung Kim, Jae-Chul Lee, Moo-Ho Won, Se-Ran Yang, Hyoung-Chun Kim, Myung-Bok Wi. Zinc Oxide Nanoparticles Exhibit Both Cyclooxygenase- and Lipoxygenase-Mediated Apoptosis in Human Bone Marrow-Derived Mesenchymal Stem Cells. Toxicological research. vol 35. issue 1. 2020-09-29. PMID:30766660. |
conclusively, these results suggest that zno nps exhibit both cox-2- and lox-mediated apoptosis by the participation of mitochondrial dysfunction in human msc cultures. |
2020-09-29 |
2023-08-13 |
human |
| Xiao Li, Huanli Xu, Cong Li, Gan Qiao, Ammad Ahmad Farooqi, Aharon Gedanken, Xiaohui Liu, Xiukun Li. Zinc-Doped Copper Oxide Nanocomposites Inhibit the Growth of Pancreatic Cancer by Inducing Autophagy Through AMPK/mTOR Pathway. Frontiers in pharmacology. vol 10. 2020-09-29. PMID:31001120. |
our previous studies have shown that zn-cuo nps could inhibit cancer cell proliferation by inducing apoptosis via ros-mediated pathway. |
2020-09-29 |
2023-08-13 |
human |
| Bashir Ahmad, Suliman Khan, Yang Liu, Mengzhou Xue, Ghulam Nabi, Sunjeet Kumar, Mohammed Alshwmi, Abdul Wakeel Qarlu. Molecular Mechanisms of Anticancer Activities of Puerarin. Cancer management and research. vol 12. 2020-09-28. PMID:32021425. |
medicinal plants are a vital source of natural products (nps) that can cure cancer through modulation of different pathways, including oxidative stress, extrinsic and intrinsic apoptosis, cell cycle, inflammation, nf-kb, pi3k/akt/mtor, ampk (jnk), mek/erk (raf)-mek-erk and autophagy. |
2020-09-28 |
2023-08-13 |
Not clear |
| Bolu Chen, Wuding Hong, Pengfei Yang, Yizhou Tang, Yu Zhao, Zoraida P Aguilar, Hengyi X. Nano Zinc Oxide Induced Fetal Mice Growth Restriction, Based on Oxide Stress and Endoplasmic Reticulum Stress. Nanomaterials (Basel, Switzerland). vol 10. issue 2. 2020-09-28. PMID:32024284. |
the rt-qpcr and immunocytochemistry data indicated that zno nps could induce placenta oxide stress, endoplasmic reticulum stress responses, apoptosis, and altered placental function. |
2020-09-28 |
2023-08-13 |
mouse |
| Bolu Chen, Wuding Hong, Pengfei Yang, Yizhou Tang, Yu Zhao, Zoraida P Aguilar, Hengyi X. Nano Zinc Oxide Induced Fetal Mice Growth Restriction, Based on Oxide Stress and Endoplasmic Reticulum Stress. Nanomaterials (Basel, Switzerland). vol 10. issue 2. 2020-09-28. PMID:32024284. |
reproductive toxicity of zno nps may be due to placental injury and function alteration caused by apoptosis, oxide stress, and endoplasmic reticulum stress after zno nps exposure. |
2020-09-28 |
2023-08-13 |
mouse |
| Ana Rita Pinho, Sandra Rebelo, Maria de Lourdes Pereir. The Impact of Zinc Oxide Nanoparticles on Male (In)Fertility. Materials (Basel, Switzerland). vol 13. issue 4. 2020-09-28. PMID:32069903. |
the capacity of zno nps to induce reactive oxygen species (ros) production, dna damage, and apoptosis represents a promise for their use in both cancer therapy and microbial treatment. |
2020-09-28 |
2023-08-13 |
Not clear |
| Enrica Chiesa, Federica Riva, Rossella Dorati, Antonietta Greco, Stefania Ricci, Silvia Pisani, Maddalena Patrini, Tiziana Modena, Bice Conti, Ida Gent. On-Chip Synthesis of Hyaluronic Acid-Based Nanoparticles for Selective Inhibition of CD44+ Human Mesenchymal Stem Cell Proliferation. Pharmaceutics. vol 12. issue 3. 2020-09-28. PMID:32183027. |
ha/cs nps were successfully loaded with a challenging water-insoluble molecule, everolimus (eve), an fda- and ema-approved anticancer drug able to lead to cell cycle arrest, reduced angiogenesis and promotion of apoptosis. |
2020-09-28 |
2023-08-13 |
human |