| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Anamaria Magdalena Tomşa, Andrei Picoş, Alina Monica Picoş, Andreea Liana Răchişa. Mitochondrial nanotargeting in malignancies (Review). Experimental and therapeutic medicine. vol 20. issue 4. 2020-09-28. PMID:32905128. |
nps can be designed in various ways, many of them targeting mitochondria causing cellular apoptosis. |
2020-09-28 |
2023-08-13 |
Not clear |
| Tingting Cui, Zhengqing Yan, Hongshuang Qin, Yuhuan Sun, Jinsong Ren, Xiaogang Q. A Sequential Target-Responsive Nanocarrier with Enhanced Tumor Penetration and Neighboring Effect In Vivo. Small (Weinheim an der Bergstrasse, Germany). vol 15. issue 42. 2020-09-24. PMID:31468717. |
zno-dox nps can release dox in lysosomes (ph 4.5) to induce cell apoptosis, and exert a neighboring effect with size reduction to infect neighboring cells. |
2020-09-24 |
2023-08-13 |
Not clear |
| Ya-Fang Xiao, Fei-Fei An, Jia-Xiong Chen, Jia Yu, Wen-Wen Tao, Zhiqiang Yu, Richard Ting, Chun-Sing Lee, Xiao-Hong Zhan. The Nanoassembly of an Intrinsically Cytotoxic Near-Infrared Dye for Multifunctionally Synergistic Theranostics. Small (Weinheim an der Bergstrasse, Germany). vol 15. issue 38. 2020-09-21. PMID:31379108. |
the prepared peg-ir-797 nanoparticles (peg-ir-797 nps) possess inherent cytotoxicity from the ir-797 dye and work as a chemotherapeutic drug which induces apoptosis of cancer cells. |
2020-09-21 |
2023-08-13 |
Not clear |
| Ankita Borah, Sindhu C Pillai, Ankit K Rochani, Vivekanandan Palaninathan, Yoshikata Nakajima, Toru Maekawa, D Sakthi Kuma. GANT61 and curcumin-loaded PLGA nanoparticles for GLI1 and PI3K/Akt-mediated inhibition in breast adenocarcinoma. Nanotechnology. vol 31. issue 18. 2020-09-17. PMID:31952056. |
the nps induced cytotoxic effects in breast cancer cells at a mid-minimal dosage followed by cell death via autophagy and apoptosis, reduction in their target protein expression along with compromising the self-renewal property of cscs as revealed by their in vitro cell studies. |
2020-09-17 |
2023-08-13 |
Not clear |
| Yongya Wu, Lu Kon. Advance on toxicity of metal nickel nanoparticles. Environmental geochemistry and health. vol 42. issue 7. 2020-09-16. PMID:31894452. |
ni nps can lead to oxidative stress, apoptosis, dna damage and inflammation and induce the increase of intracellular reactive oxygen species. |
2020-09-16 |
2023-08-13 |
Not clear |
| Dan Yang, Meijuan Zhang, Yu Gan, Si Yang, Jinglei Wang, Mei Yu, Jie Wei, Jiaxiang Che. Involvement of oxidative stress in ZnO NPs-induced apoptosis and autophagy of mouse GC-1 spg cells. Ecotoxicology and environmental safety. vol 202. 2020-09-07. PMID:32800232. |
herein, mouse-derived spermatogonia cell line gc-1 spg cells were treated with zno nps for 24 h in the presence or absence of radical scavenger n-acetyl-l-cysteine (nac) or autophagy inhibitor 3-methyladenine (3-ma), then cell viability was observed by mtt assay; apoptosis was observed by western blotting analysis and annexinv-fitc/pi assay, respectively; autophagy was detected by western blotting analysis and transmission electron microscopy, respectively; and the contents of mda and gsh and the activities of sod and gsh-px were measured by oxidative stress kits. |
2020-09-07 |
2023-08-13 |
mouse |
| Dan Yang, Meijuan Zhang, Yu Gan, Si Yang, Jinglei Wang, Mei Yu, Jie Wei, Jiaxiang Che. Involvement of oxidative stress in ZnO NPs-induced apoptosis and autophagy of mouse GC-1 spg cells. Ecotoxicology and environmental safety. vol 202. 2020-09-07. PMID:32800232. |
the present study showed that zno nps exposure inhibited viability and induced apoptosis of mouse gc-1 spg cells. |
2020-09-07 |
2023-08-13 |
mouse |
| Dan Yang, Meijuan Zhang, Yu Gan, Si Yang, Jinglei Wang, Mei Yu, Jie Wei, Jiaxiang Che. Involvement of oxidative stress in ZnO NPs-induced apoptosis and autophagy of mouse GC-1 spg cells. Ecotoxicology and environmental safety. vol 202. 2020-09-07. PMID:32800232. |
oxidative stress could be induced by zno nps; moreover, inhibition of oxidative stress could alleviate the induction of apoptosis and autophagy by zno nps. |
2020-09-07 |
2023-08-13 |
mouse |
| Dan Yang, Meijuan Zhang, Yu Gan, Si Yang, Jinglei Wang, Mei Yu, Jie Wei, Jiaxiang Che. Involvement of oxidative stress in ZnO NPs-induced apoptosis and autophagy of mouse GC-1 spg cells. Ecotoxicology and environmental safety. vol 202. 2020-09-07. PMID:32800232. |
inhibition of autophagy by 3-ma could rescue the inhibition of cell viability and induction of apoptosis by zno nps, which indicated that autophagy might have cytotoxic effect on zno nps-induced apoptosis. |
2020-09-07 |
2023-08-13 |
mouse |
| Peng Ji, Haiqin Huang, Shirui Yuan, Le Wang, Siqi Wang, Yiwei Chen, Na Feng, Hanitrarimalala Veroniaina, Ziheng Wu, Zhenghong Wu, Xiaole Q. ROS-Mediated Apoptosis and Anticancer Effect Achieved by Artesunate and Auxiliary Fe(II) Released from Ferriferous Oxide-Containing Recombinant Apoferritin. Advanced healthcare materials. vol 8. issue 23. 2020-08-31. PMID:31701665. |
after being captured in the acidic cavity of endosomes, m-hfn@as nps can simultaneously release fe(ii) and allow as to activate satisfactory ros-mediated apoptosis. |
2020-08-31 |
2023-08-13 |
human |
| Badriyah Alotaibi, Ehab Tousson, Thanaa A El-Masry, Najla Altwaijry, Asmaa Sale. Ehrlich ascites carcinoma as model for studying the cardiac protective effects of curcumin nanoparticles against cardiac damage in female mice. Environmental toxicology. 2020-08-31. PMID:32865349. |
current work aimed to define the cardiac defensive effects of curcumin nanoparticles (cur nps) against eac induced cardiac toxicity, injury, and alterations in apoptosis, proliferation, and cytokines immunoreactivity. |
2020-08-31 |
2023-08-13 |
mouse |
| Srishti Agarwal, M Sheikh Mohamed, Toru Mizuki, Toru Maekawa, D Sakthi Kuma. Chlorotoxin modified morusin-PLGA nanoparticles for targeted glioblastoma therapy. Journal of materials chemistry. B. vol 7. issue 39. 2020-08-20. PMID:31423502. |
antiproliferative, cell apoptosis, and other cell-based assays demonstrated that the plga-mor-ctx nps resulted in enhanced inhibitory effects on u87 and gi-1 glioma cells. |
2020-08-20 |
2023-08-13 |
human |
| Danielle M Valcourt, Megan N Dang, Emily S Da. IR820-loaded PLGA nanoparticles for photothermal therapy of triple-negative breast cancer. Journal of biomedical materials research. Part A. vol 107. issue 8. 2020-08-12. PMID:30920169. |
the results demonstrate that these nps are potent mediators of ptt that induce cell death primarily through apoptosis to effectively hinder the growth of tnbc tumors. |
2020-08-12 |
2023-08-13 |
Not clear |
| Di Liu, Feiyang Jin, Gaofeng Shu, Xiaoling Xu, Jing Qi, Xuqi Kang, Hui Yu, Kongjun Lu, Saiping Jiang, Feng Han, Jian You, Yongzhong Du, Jiansong J. Enhanced efficiency of mitochondria-targeted peptide SS-31 for acute kidney injury by pH-responsive and AKI-kidney targeted nanopolyplexes. Biomaterials. vol 211. 2020-08-12. PMID:31085359. |
it was found that nps had excellent ability to decrease oxidative stress, protect mitochondrial structure, reduce inflammatory response, reduce apoptosis and necrosis of tubular cells after intravenious administration. |
2020-08-12 |
2023-08-13 |
mouse |
| Di Liu, Feiyang Jin, Gaofeng Shu, Xiaoling Xu, Jing Qi, Xuqi Kang, Hui Yu, Kongjun Lu, Saiping Jiang, Feng Han, Jian You, Yongzhong Du, Jiansong J. Enhanced efficiency of mitochondria-targeted peptide SS-31 for acute kidney injury by pH-responsive and AKI-kidney targeted nanopolyplexes. Biomaterials. vol 211. 2020-08-12. PMID:31085359. |
overall, the results suggest that the nps have significant potential to enhance the specific biodistribution and delivery of ss-31, therefore have good effects on reducing oxidative stress and inflammation, preventing tubular apoptosis and necrosis. |
2020-08-12 |
2023-08-13 |
mouse |
| Wangcheng Hu, Zhou Yu, Xiaojie Gao, Yongya Wu, Meng Tang, Lu Kon. Study on the damage of sperm induced by nickel nanoparticle exposure. Environmental geochemistry and health. vol 42. issue 6. 2020-08-11. PMID:31278585. |
many studies have shown that ni nps can induce apoptosis, oxidative stress and dna damage. |
2020-08-11 |
2023-08-13 |
mouse |
| Fashui Hong, Yingjun Zho. Spermatogenic Apoptosis and the Involvement of the Nrf2 Pathway in Male Mice Following Exposure to Nano Titanium Dioxide. Journal of biomedical nanotechnology. vol 16. issue 3. 2020-08-03. PMID:32493547. |
our findings suggested that tio₂ nps could cross the blood-testis barrier and were aggregated or deposed in spermatogenic cells, which resulted in spermatogenic apoptosis. |
2020-08-03 |
2023-08-13 |
mouse |
| Fashui Hong, Yingjun Zho. Spermatogenic Apoptosis and the Involvement of the Nrf2 Pathway in Male Mice Following Exposure to Nano Titanium Dioxide. Journal of biomedical nanotechnology. vol 16. issue 3. 2020-08-03. PMID:32493547. |
the present study implies that tio₂ nps could lead to spermatogenic apoptosis, and nrf2 is the initial factor that responded to such reproductive toxicity by regulating the expression of antioxidative proteins. |
2020-08-03 |
2023-08-13 |
mouse |
| Xuejing Huang, Fengjie Wan, Lun Ma, Jonathan B Phan, Rebecca Xueyi Lim, Cuiping Li, Jiagui Chen, Jinghuan Deng, Yasi Li, Wei Chen, Min H. Investigation of copper-cysteamine nanoparticles as a new photosensitizer for anti-hepatocellular carcinoma. Cancer biology & therapy. vol 20. issue 6. 2020-07-27. PMID:30727796. |
in addition, we found that cell death was induced by cu-cy nps, which is associated with cellular apoptosis. |
2020-07-27 |
2023-08-13 |
Not clear |
| Qiong Wang, Chenming Zou, Lingying Wang, Xueqin Gao, Jindan Wu, Songwei Tan, Gang W. Doxorubicin and adjudin co-loaded pH-sensitive nanoparticles for the treatment of drug-resistant cancer. Acta biomaterialia. vol 94. 2020-07-21. PMID:31141733. |
the nps can realize precise ratiometric control of drugs being loaded, increase cellular uptake of the drugs, induce mitochondrial dysfunction and augment tumor treatment efficiency by inducing apoptosis. |
2020-07-21 |
2023-08-13 |
Not clear |