| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lei Luo, Yiming Qi, Hong Zhong, Shinan Jiang, Hu Zhang, Hao Cai, Yahui Wu, Zhongwei Gu, Qiyong Gong, Kui Lu. GSH-sensitive polymeric prodrug: Synthesis and loading with photosensitizers as nanoscale chemo-photodynamic anti-cancer nanomedicine. Acta pharmaceutica Sinica. B. vol 12. issue 1. 2022-02-07. PMID:35127396. |
nps(ce6) showed a chemo-photodynamic therapeutic effect to kill 4t1 murine breast cancer cells, which was confirmed from a collapsed cell morphology, a lifted level in the intracellular reactive oxygen species, a reduced viability and induced apoptosis. |
2022-02-07 |
2023-08-13 |
Not clear |
| Saad Alkahtani, Saud Alarifi, Nada H Aljarba, Hamzah A Alghamdi, Abdullah A Alkahtan. Mesoporous SBA-15 Silica-Loaded Nano-formulation of Quercetin: A Probable Radio-Sensitizer for Lung Carcinoma. Dose-response : a publication of International Hormesis Society. vol 20. issue 1. 2022-02-03. PMID:35110975. |
moreover, the apoptotic pathway of synthesized q-sba-15 nps examined that the q-sba-15-mediated apoptosis |
2022-02-03 |
2023-08-13 |
human |
| Xiaoyu Li, Peng Zhou, Zhen Luo, Ru Feng, Lu Wan. Hohenbuehelia serotina polysaccharides self-assembled nanoparticles for delivery of quercetin and their anti-proliferative activities during gastrointestinal digestion in vitro. International journal of biological macromolecules. 2022-01-30. PMID:35093441. |
compared with undigested ones, qc-hsp nps after gastrointestinal digestion exhibited the more significant anti-proliferative activity on hela cells through accumulation of intracellular ros, arrest of cell cycle at g2/m phase by regulation of cyclin b1, cdk1, p53 and p21 and induction of apoptosis by er apoptosis pathway. |
2022-01-30 |
2023-08-13 |
Not clear |
| Xiaoli Cai, Shichao Ding, Qiurong Shi, Zhaoyuan Lyu, Dong Liu, Wen-Ji Dong, Min Du, Prashanta Dutta, Yang Song, Dan Du, Yuehe Li. Eyeball-Like Yolk-Shell Bimetallic Nanoparticles for Synergistic Photodynamic-Photothermal Therapy. ACS applied bio materials. vol 3. issue 9. 2022-01-13. PMID:35021820. |
results showed that the obtained au@pd-peg-fa-ce6 (appfc) nps were selectively accumulated at the tumor site and induced cell apoptosis effectively due to the target specificity and synergistic phototherapy effect. |
2022-01-13 |
2023-08-13 |
Not clear |
| Nabil A Alhakamy, Mohammed W Al-Rabia, Hani Z Asfour, Samah Alshehri, Waleed S Alharbi, Abdulrahman Halawani, Abdulmohsin J Alamoudi, Ahmad O Noor, Douha F Bannan, Usama A Fahmy, Sabna Kott. 2-Methoxy-estradiol Loaded Alpha Lipoic Acid Nanoparticles Augment Cytotoxicity in MCF-7 Breast Cancer Cells. Dose-response : a publication of International Hormesis Society. vol 19. issue 4. 2022-01-06. PMID:34987331. |
there was a 1.2-fold increase in apoptosis and a 3.46-fold increase in necrosis of the mcf-7 cells when incubated with 2me-ala nps when compared to control cells. |
2022-01-06 |
2023-08-13 |
Not clear |
| Nabil A Alhakamy, Mohammed W Al-Rabia, Hani Z Asfour, Samah Alshehri, Waleed S Alharbi, Abdulrahman Halawani, Abdulmohsin J Alamoudi, Ahmad O Noor, Douha F Bannan, Usama A Fahmy, Sabna Kott. 2-Methoxy-estradiol Loaded Alpha Lipoic Acid Nanoparticles Augment Cytotoxicity in MCF-7 Breast Cancer Cells. Dose-response : a publication of International Hormesis Society. vol 19. issue 4. 2022-01-06. PMID:34987331. |
this increased apoptosis was also associated with increased ros and increased p53 expression in 2me-ala nps treated cells compared to the raw-2 me group. |
2022-01-06 |
2023-08-13 |
Not clear |
| Kang Pa Lee, Suji Baek, Myeong Sik Yoon, Ji Soo Park, Bok Sil Hong, Sang Ju Lee, Seung Jun Oh, Seung Hae Kwon, Ruda Lee, Dae Ho Lee, Kang-Seo Park, Byung Seok Moo. Potential anticancer effect of aspirin and 2'-hydroxy-2,3,5'-trimethoxychalcone-linked polymeric micelles against cervical cancer through apoptosis. Oncology letters. vol 23. issue 1. 2021-12-30. PMID:34966447. |
in the present study, we investigated whether certain nanoparticles (nps), comprising aspirin conjugated 2'-hydroxy-2,3,5'-trimethoxychalcone chemicals, could induce the apoptosis of cancer cells. |
2021-12-30 |
2023-08-13 |
Not clear |
| Xiaoxia Yang, Pengfei Shang, Jianbo Ji, Christina Malichewe, Zhiyin Yao, Jing Liao, Dandan Du, Chao Sun, Lei Wang, Ya-Jie Tang, Xiuli Gu. Hyaluronic Acid-Modified Nanoparticles Self-Assembled from Linoleic Acid-Conjugated Chitosan for the Codelivery of miR34a and Doxorubicin in Resistant Breast Cancer. Molecular pharmaceutics. 2021-12-15. PMID:34910493. |
in addition, the ccmdh nps could inhibit proliferation and promote apoptosis by regulating the protein expression of b-cell lymphoma-2 (bcl-2) and poly(adp-ribose) polymerase (parp) and inhibit invasion, metastasis, and adhesion by regulating e-cadherin, n-cadherin, mmp2, cd44, and snail molecules. |
2021-12-15 |
2023-08-13 |
mouse |
| Shengli Liu, Honglian Liu, Hao Sun, Shengming Deng, Ling Yue, Zhen Weng, Jianfeng Yang, Bin Zuo, Yang He, Bin Zhan. (cRGD)2 peptides modified nanoparticles increase tumor-targeting therapeutic effects by co-delivery of albendazole and iodine-131. Anti-cancer drugs. vol 33. issue 1. 2021-12-14. PMID:34261920. |
western blotting analysis showed that the nps, as well as free abz, cell-dependently induced autophagy and apoptosis by restraining or promoting the expression of p-p38 and p-jnk mapk. |
2021-12-14 |
2023-08-15 |
mouse |
| Shengli Liu, Honglian Liu, Hao Sun, Shengming Deng, Ling Yue, Zhen Weng, Jianfeng Yang, Bin Zuo, Yang He, Bin Zhan. (cRGD)2 peptides modified nanoparticles increase tumor-targeting therapeutic effects by co-delivery of albendazole and iodine-131. Anti-cancer drugs. vol 33. issue 1. 2021-12-14. PMID:34261920. |
furthermore, 131i-(crgd)2/hsa@abz nps significantly suppressed tumor growth by restraining proliferation and promoting apoptosis in vivo. |
2021-12-14 |
2023-08-15 |
mouse |
| Xiang Hui Li, Zhiqiang Zhang, Xia Ma, Zhen Huan Guo, Xueting Ban, Zheng Tian, Li Zhao, Qiqi Liu, Qigai H. Biomimetic amphiphilic FAAP NPs nanoparticles: Synthesis, characterization and antivirus activity. International immunopharmacology. vol 101. issue Pt A. 2021-12-09. PMID:34619499. |
in addition, we found that faap nps inhibited ppv infection-induced pk-15 cell apoptosis, which was associated with regulating antioxidant and anti-inflammatory signaling pathways. |
2021-12-09 |
2023-08-13 |
Not clear |
| Xiang Hui Li, Zhiqiang Zhang, Xia Ma, Zhen Huan Guo, Xueting Ban, Zheng Tian, Li Zhao, Qiqi Liu, Qigai H. Biomimetic amphiphilic FAAP NPs nanoparticles: Synthesis, characterization and antivirus activity. International immunopharmacology. vol 101. issue Pt A. 2021-12-09. PMID:34619499. |
importantly, we showed that faap nps blocked ppv infection-induced mitochondrial apoptosis in pk-15 cells via a p53/bh3 domain molecular-dependent mechanism. |
2021-12-09 |
2023-08-13 |
Not clear |
| Sha-Sha Li, Cheng-Mei Zhang, Jing-De Wu, Chao Liu, Zhao-Peng Li. A branched small molecule-drug conjugate nanomedicine strategy for the targeted HCC chemotherapy. European journal of medicinal chemistry. vol 228. 2021-12-09. PMID:34883290. |
in cellular level, the bsmdc 1 nps targeted asialoglycoprotein receptor (asgpr)-overexpressing hepg2 cells, were effectively taken up in the cells and released in tumor microenvironments, inhibited the hepg2 cell proliferation, arrested hepg2 cell in g2/m phase and induced tumor cell apoptosis. |
2021-12-09 |
2023-08-13 |
mouse |
| Lingling Qi, Chao Liu, Yingying Zhang, Zheao Zhang, Hongxia Duan, Heming Zhao, Xin Xin, Liqing Chen, Mingji Jin, Youyan Guan, Zhonggao Gao, Wei Huan. Development of Mitomycin C-Loaded Nanoparticles Prepared Using the Micellar Assembly Driven by the Combined Effect of Hydrogen Bonding and π-π Stacking and Its Therapeutic Application in Bladder Cancer. Pharmaceutics. vol 13. issue 11. 2021-11-30. PMID:34834192. |
the results show that mmc nps had a high uptake efficiency, could promote cell apoptosis, and had a strong inhibitory effect on cell proliferation. |
2021-11-30 |
2023-08-13 |
Not clear |
| Lingling Qi, Chao Liu, Yingying Zhang, Zheao Zhang, Hongxia Duan, Heming Zhao, Xin Xin, Liqing Chen, Mingji Jin, Youyan Guan, Zhonggao Gao, Wei Huan. Development of Mitomycin C-Loaded Nanoparticles Prepared Using the Micellar Assembly Driven by the Combined Effect of Hydrogen Bonding and π-π Stacking and Its Therapeutic Application in Bladder Cancer. Pharmaceutics. vol 13. issue 11. 2021-11-30. PMID:34834192. |
more importantly, the as-prepared nps could effectively induce tumor cell apoptosis and inhibit tumor growth and metastasis in vivo. |
2021-11-30 |
2023-08-13 |
Not clear |
| Hongwei Zheng, Wenlun Wang, Shichang Li, Lin Ha. The Effect of Zbxz23ir-21 NANO(nanomaterials) Delivery Vector on Apoptosis and PTEN(phosphatase and tensin homolog deleted on chromosome ten)/PI3K(Intracellular phosphatidylinositol kinase)/AKT(related to the A and C kinase) in Children with CHOLESTEATOMA in Middle Ear. Bioengineered. vol 12. issue 1. 2021-11-24. PMID:34696703. |
the results of cell level experiments in vitro showed that free rubine caused about 15% apoptosis, which was not different from rc nps. |
2021-11-24 |
2023-08-13 |
mouse |
| Isidora Tošić, Lisa N Heppler, Susana P Egusquiaguirre, Natalie Boehnke, Santiago Correa, Daniel F Costa, Elizabeth A Grossman Moore, Sharmistha Pal, Douglas S Richardson, Alexander R Ivanov, Daphne A Haas-Kogan, Daniel K Nomura, Paula T Hammond, David A Fran. Lipidome-based Targeting of STAT3-driven Breast Cancer Cells Using Poly-l-glutamic Acid-coated Layer-by-Layer Nanoparticles. Molecular cancer therapeutics. vol 20. issue 4. 2021-11-19. PMID:33536189. |
we found that cisplatin-loaded ple-nps induced apoptosis of stat3-driven cells at lower doses compared with both unencapsulated cisplatin and cisplatin-loaded nontargeted nps. |
2021-11-19 |
2023-08-13 |
Not clear |
| Paulina Wigner, Krzysztof Zielinski, Sylwia Michlewska, Paulina Danielska, Agnieszka Marczak, Eduardo Junior Ricci, Ralph Santos-Oliveira, Marzena Szwe. Disturbance of cellular homeostasis as a molecular risk evaluation of human endothelial cells exposed to nanoparticles. Scientific reports. vol 11. issue 1. 2021-11-15. PMID:33589697. |
the tested nps induced not only dna strand-breaks and alkali-labile sites, but also internucleosomal dna fragmentation, visualized as a dna ladder pattern typical of apoptosis. |
2021-11-15 |
2023-08-13 |
human |
| Hriday Bera, Mohammed A Abosheasha, Yoshihiro Ito, Motoki Ued. Hypoxia-responsive pullulan-based nanoparticles as erlotinib carriers. International journal of biological macromolecules. vol 191. 2021-11-11. PMID:34600326. |
the erl-loaded nps suppressed hela cell proliferation and induced apoptosis more efficiently than the pristine drug. |
2021-11-11 |
2023-08-13 |
Not clear |
| Wen Li, Zhiwen Cao, Liuchunyang Yu, Qingcai Huang, Dongjie Zhu, Cheng Lu, Aiping Lu, Yuanyan Li. Hierarchical drug release designed Au @PDA-PEG-MTX NPs for targeted delivery to breast cancer with combined photothermal-chemotherapy. Journal of nanobiotechnology. vol 19. issue 1. 2021-11-08. PMID:34001161. |
au @pda-peg-mtx nps under near infra-red region (nir) irradiation showed effective photothermal therapy against mda-mb-231 human bc cells growth in vitro by inducing apoptosis through triggering reactive oxygen species (ros) overproduction and generating excessive heat. |
2021-11-08 |
2023-08-13 |
human |