| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xuewei Yin, Zonghong Li, Chunyi Lyu, Yan Wang, Shumin Ding, Chenchen Ma, Jingyi Wang, Siyuan Cui, Jinxin Wang, Dadong Guo, Ruirong X. Induced Effect of Zinc oxide nanoparticles on human acute myeloid leukemia cell apoptosis by regulating mitochondrial division. IUBMB life. 2022-04-06. PMID:35383422. |
next, the expression of drp-1, bcl-2, bax mrna and protein was detected, and the effects of zno nps on the levels of reactive oxygen species (ros), mitochondrial membrane potential (Δψm), apoptosis and atp generation in thp-1 cells were measured. |
2022-04-06 |
2023-08-13 |
human |
| Xuewei Yin, Zonghong Li, Chunyi Lyu, Yan Wang, Shumin Ding, Chenchen Ma, Jingyi Wang, Siyuan Cui, Jinxin Wang, Dadong Guo, Ruirong X. Induced Effect of Zinc oxide nanoparticles on human acute myeloid leukemia cell apoptosis by regulating mitochondrial division. IUBMB life. 2022-04-06. PMID:35383422. |
zno nps can reduce the cell Δψm and atp levels, induce the ros production, and increase the levels of mitochondrial division and apoptosis. |
2022-04-06 |
2023-08-13 |
human |
| Xuewei Yin, Zonghong Li, Chunyi Lyu, Yan Wang, Shumin Ding, Chenchen Ma, Jingyi Wang, Siyuan Cui, Jinxin Wang, Dadong Guo, Ruirong X. Induced Effect of Zinc oxide nanoparticles on human acute myeloid leukemia cell apoptosis by regulating mitochondrial division. IUBMB life. 2022-04-06. PMID:35383422. |
in contrast, the apoptotic level was significantly reduced after intervention of drp-1 inhibitor, suggesting that zno nps can induce the apoptosis of thp-1 cells by regulating mitochondrial division. |
2022-04-06 |
2023-08-13 |
human |
| Sajedeh Daei, Roghayeh Abbasalipourkabir, Maryam Khajvand-Abedini, Nasrin Ziamajid. The Alleviative Efficacy of Vitamins A, C, and E Against Zinc Oxide Nanoparticles-Induced Hepatic Damage by Reducing Apoptosis in Rats. Biological trace element research. 2022-04-02. PMID:35364806. |
according to previous reports, zinc oxide (zno) nps cause toxic effects in tissues via inducing apoptosis. |
2022-04-02 |
2023-08-13 |
human |
| Sajedeh Daei, Roghayeh Abbasalipourkabir, Maryam Khajvand-Abedini, Nasrin Ziamajid. The Alleviative Efficacy of Vitamins A, C, and E Against Zinc Oxide Nanoparticles-Induced Hepatic Damage by Reducing Apoptosis in Rats. Biological trace element research. 2022-04-02. PMID:35364806. |
thus, administration of vits a, c, and e may be effective in preventing liver damage and apoptosis caused by zno nps. |
2022-04-02 |
2023-08-13 |
human |
| Xiangyang Zhang, Min Wang, Junyi Feng, Bin Qin, Chenglin Zhang, Chengshen Zhu, Wentao Liu, Yaohe Wang, Wei Liu, Lei Huang, Shuangshuang Lu, Zhimin Wan. Multifunctional nanoparticles co-loaded with Adriamycin and MDR-targeting siRNAs for treatment of chemotherapy-resistant esophageal cancer. Journal of nanobiotechnology. vol 20. issue 1. 2022-03-29. PMID:35346194. |
we have designed a novel and versatile self-assembling nanoparticle (np) platform on a multifunctional carboxymethyl chitosan base to simultaneously deliver adriamycin, and sirnas targeting mvp and bcl2 (ceamb nps), thus reducing drug efflux and promoting apoptosis of esophageal cancer cells. |
2022-03-29 |
2023-08-13 |
mouse |
| Alaa A A Aljabali, Mohammad A Obeid, Hamid A Bakshi, Walhan Alshaer, Raed M Ennab, Bahaa Al-Trad, Wesam Al Khateeb, Khalid M Al-Batayneh, Abdulfattah Al-Kadash, Shrouq Alsotari, Hamdi Nsairat, Murtaza M Tambuwal. Synthesis, Characterization, and Assessment of Anti-Cancer Potential of ZnO Nanoparticles in an In Vitro Model of Breast Cancer. Molecules (Basel, Switzerland). vol 27. issue 6. 2022-03-26. PMID:35335190. |
in cancer treatment, zno nanoparticles (nps) have the capacity to specifically and compellingly activate apoptosis of cancer cells. |
2022-03-26 |
2023-08-13 |
Not clear |
| Yin Yin Myat, Tanasait Ngawhirunpat, Theerasak Rojanarata, Praneet Opanasopit, Mark Bradley, Prasopchai Patrojanasophon, Chaiyakarn Pornpitchanaron. Synthesis of Polyethylene Glycol Diacrylate/Acrylic Acid Nanoparticles as Nanocarriers for the Controlled Delivery of Doxorubicin to Colorectal Cancer Cells. Pharmaceutics. vol 14. issue 3. 2022-03-26. PMID:35335856. |
dox-loaded pegda/aa nps (dox-nps) were able to effectively kill the colorectal cancer cell line (ht-29) with the dox-nps accumulating inside the cell and killing the cell through the apoptosis pathway. |
2022-03-26 |
2023-08-13 |
Not clear |
| Hector Katifelis, Maria-Paraskevi Nikou, Iuliia Mukha, Nadiia Vityuk, Nefeli Lagopati, Christina Piperi, Ammad Ahmad Farooqi, Natassa Pippa, Efstathios P Efstathopoulos, Maria Gazoul. Ag/Au Bimetallic Nanoparticles Trigger Different Cell Death Pathways and Affect Damage Associated Molecular Pattern Release in Human Cell Lines. Cancers. vol 14. issue 6. 2022-03-25. PMID:35326698. |
we studied the cytotoxic effects of agau nps, ag nps and au nps with regard to the programmed cell death (apoptosis, necroptosis, pyroptosis) and the secretion/release of hsp70 and hmgb1. |
2022-03-25 |
2023-08-13 |
human |
| Wenhao Zhong, Xinyu Zhang, Xiao Duan, Hengyu Liu, Yifen Fang, Moucheng Luo, Zhengwen Fang, Congxiu Miao, Dongjun Lin, Jun W. Redox-responsive Self-assembled Polymeric Nanoprodrug for Delivery of Gemcitabine in B-cell Lymphoma Therapy. Acta biomaterialia. 2022-03-25. PMID:35331940. |
the self-assembled subsize (< 100 nm) gem-s-s-peg (gsp nps) with considerable loading capacity (≈ 24.6%) exhibited on-demand and accurate control of gemcitabine release under a simulated tumor microenvironment and thus significantly induced the apoptosis of b-cell lymphoma in vitro. |
2022-03-25 |
2023-08-13 |
Not clear |
| Fengyan Song, Xinwen Ou, Tsu Yu Chou, Junkai Liu, Hui Gao, Ruoyao Zhang, Xiaolin Huang, Zujin Zhao, Jianwei Sun, Sijie Chen, Jacky W Y Lam, Ben Zhong Tan. Oxygen Quenching-Resistant Nanoaggregates with Aggregation-Induced Delayed Fluorescence for Time-Resolved Mapping of Intracellular Microviscosity. ACS nano. 2022-03-23. PMID:35318852. |
the feasibility of fkp-pta nanoparticles (nps) for microviscosity mapping through trli was demonstrated by monitoring the variation of microviscosity inside hepg2 cancer cells, which demonstrated a value change from 14.9 cp to 216.9 cp during the apoptosis. |
2022-03-23 |
2023-08-13 |
Not clear |
| Meng Yang, Wen-Xiong Wan. Differential cascading cellular and subcellular toxicity induced by two sizes of nanoplastics. The Science of the total environment. 2022-03-19. PMID:35304139. |
our study demonstrated a complicated relationship among lysosome damage, autophagy activation, and apoptosis, leading to contrasting toxicity of nps of different sizes. |
2022-03-19 |
2023-08-13 |
zebrafish |
| Shima Shahrad, Mohammad Rajabi, Hamidreza Javadi, Ali Akbar Karimi Zarchi, Mohammad Hasan Darvish. Targeting lung cancer cells with MUC1 aptamer-functionalized PLA-PEG nanocarriers. Scientific reports. vol 12. issue 1. 2022-03-19. PMID:35304550. |
targeted nanocarriers (pla-peg-apt/dox nps at w/w ratio 10:1) induced higher apoptosis rate (36.3 ± 3.44%) for 24 h in muc1 positive a-549 cancer cells in compare to non-targeted form (pla-peg/dox nps at w/w ratio 10:1, 11.37 ± 1.65%) and free dox (4.35 ± 0.81%). |
2022-03-19 |
2023-08-13 |
Not clear |
| Zhenkun Ren, Xibin Han, Lixin Wang, Yi Wan. Hyaluronic acid functionalized ZnO nanoparticles co-deliver AS and GOD for synergistic cancer starvation and oxidative damage. Scientific reports. vol 12. issue 1. 2022-03-18. PMID:35301389. |
the cellular and in vivo experiment showed that co-delivery of as and god via hazno nps could effectively induce the overproduction of ros and cut the glucose supply of tumor cells, and thus result in efficient cell apoptosis and tumor inhibition. |
2022-03-18 |
2023-08-13 |
Not clear |
| Xiuli Zheng, Dayi Pan, Guonian Zhu, Lu Zhang, Apanpreet Bhamra, Rongjun Chen, Hu Zhang, Qiyong Gong, Zhongwei Gu, Kui Lu. A dendritic polymer-based nanosystem mediates drug penetration and irreversible endoplasmic reticulum stresses in tumor via neighboring effect. Advanced materials (Deerfield Beach, Fla.). 2022-03-15. PMID:35289966. |
herein, we develop ph/redox-responsive dendritic polymer-based nps to amplify the neighboring effect for improving drug penetration and driving cell apoptosis via combination therapy. |
2022-03-15 |
2023-08-13 |
Not clear |
| Xiuli Zheng, Dayi Pan, Guonian Zhu, Lu Zhang, Apanpreet Bhamra, Rongjun Chen, Hu Zhang, Qiyong Gong, Zhongwei Gu, Kui Lu. A dendritic polymer-based nanosystem mediates drug penetration and irreversible endoplasmic reticulum stresses in tumor via neighboring effect. Advanced materials (Deerfield Beach, Fla.). 2022-03-15. PMID:35289966. |
pyropheophorbide a (ppa) is conjugated with pegylated dendritic peptides via disulfide bonds and doxorubicin (dox) encapsulated in the conjugate to construct dual-responsive nps, pdpp@d. delayed released dox and ppa from pdpp@d exert their combination therapeutic effect to induce cell apoptosis, and then they are liberated out of dying cells to amplify the neighboring effect, resulting in their diffusion through the dense ecm and penetration into solid tumors. |
2022-03-15 |
2023-08-13 |
Not clear |
| Ke Sun, Xiao Lu, Chuanrong Yin, Jinsong Gu. In vitro antitumor activity of nano-pulse stimulation on human anaplastic thyroid cancer cells through nitric oxide-dependent mechanisms. Bioelectrochemistry (Amsterdam, Netherlands). vol 145. 2022-03-11. PMID:35276436. |
the cell line 8305c were treated with nps and the cck-8 assay, clonogenic assay, apoptosis assay and nitric oxide synthase (nos) activity assay were used to test cell proliferation, apoptosis and nos changes respectively. |
2022-03-11 |
2023-08-13 |
human |
| Ke Sun, Xiao Lu, Chuanrong Yin, Jinsong Gu. In vitro antitumor activity of nano-pulse stimulation on human anaplastic thyroid cancer cells through nitric oxide-dependent mechanisms. Bioelectrochemistry (Amsterdam, Netherlands). vol 145. 2022-03-11. PMID:35276436. |
our results showed that nps can significantly (p < 0.05) inhibit atc cell proliferation and induce apoptosis in a field strength-dependent manner. |
2022-03-11 |
2023-08-13 |
human |
| Pouya Dehghankelishadi, Michelle F Maritz, Parisa Badiee, Benjamin Thierr. High density lipoprotein nanoparticle as delivery system for radio-sensitising miRNA; An investigation in 2D/3D head and neck cancer models. International journal of pharmaceutics. 2022-02-17. PMID:35176332. |
profiling of the radiation response in the um-scc-1 head and neck cancer cell line confirmed reduced metabolic activity and increased radiation induced apoptosis upon treatment with mir-34a-hdl nps. |
2022-02-17 |
2023-08-13 |
Not clear |
| Lei Luo, Yiming Qi, Hong Zhong, Shinan Jiang, Hu Zhang, Hao Cai, Yahui Wu, Zhongwei Gu, Qiyong Gong, Kui Lu. GSH-sensitive polymeric prodrug: Synthesis and loading with photosensitizers as nanoscale chemo-photodynamic anti-cancer nanomedicine. Acta pharmaceutica Sinica. B. vol 12. issue 1. 2022-02-07. PMID:35127396. |
nps(ce6) showed a chemo-photodynamic therapeutic effect to kill 4t1 murine breast cancer cells, which was confirmed from a collapsed cell morphology, a lifted level in the intracellular reactive oxygen species, a reduced viability and induced apoptosis. |
2022-02-07 |
2023-08-13 |
Not clear |